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The map label for this gene is ctaC [H]

Identifier: 116626617

GI number: 116626617

Start: 9505543

End: 9506568

Strand: Direct

Name: ctaC [H]

Synonym: Acid_7580

Alternate gene names: 116626617

Gene position: 9505543-9506568 (Clockwise)

Preceding gene: 116626616

Following gene: 116626618

Centisome position: 95.38

GC content: 59.55

Gene sequence:

>1026_bases
ATGAACATGATGGGGGCGCCCCTCGCTTTGCTCTTCCTCGCGAACGCTGCCTTCGCACAGACTGCGCGTCCCGCACTGAG
TCCTACGACGATATTCTCGCCGGTCTCGACGCCAGCCGATTCGATCTTTCACCTTTCCCTCTTCGTACTTGCTGTTGCCG
CGGCCATATTCACGGTCGTCTTCAGCCTGCTGATCTACTCGCTCGTACGATTCCGAAAGCGGAGCGACGATGACGGGCGC
GAGCCGCCGCAAATCTATGGCAGCAATCAAGTGGAACTTGCATGGACAGTAGTTCCGATCCTGATCGTGGTGACTCTGTT
CATGGCAACGGCGCGAGTGATCGCCGGGACGCTGAAGGCTTCACGTCCGTCAAGCTCCGTTGAAGTGGTGGCCGTCGGTC
ATCAGTTCTGGTGGGAGTTTCGTTATCCGGGACTCAAGGTAGTGACAGCCAATGAACTGCACGTGCCGCTGAGCGAGCCA
GGGCATCCGACCCCGACGTTTATCACGCTGACTTCCGCCGATACGGATCACAGCTTCTGGGTCCCTCGCCTTGCGGGCAA
AACAGACTTGATCCCGAATCGCGTAAATACGATGTGGATTGATCCCCACGAACCGGGACTGTACCTGGGACAGTGCGCGC
AGTATTGCGGAACGCAGCACGCCAAGATGCTGCTTCGCGTCTACGTCCAGACCCGTGACGAGTTCGCCCGCTGGATTCAA
GAACAACGCCAGCCCGCACATGCAGAGGACAGCGTGTATGCGGGGCGGCAGATCTTCGAGACCACGGCCTGCATCAACTG
CCACACCGTAACCGGGACAACAGCCCATGGCACCTTCGGTCCCGATCTGACTCACCTGATGAGCCGGGACACGATTGCGT
CCGGAGCCGTGCCGAATTCGCCCGAGAACCTCCGTCAGTGGATTCGGAATCCTGACGCGATGAAGCCCGGGTGCAGAATG
CCGGCGATGAACTTGGGGGAGCGGGAGATAAGCGCCGTAGCCGCATACCTGGAGACACTTCGGTGA

Upstream 100 bases:

>100_bases
CGCATTCCTGGTGGTTGCCCGCGGGCCCAGAGCTCACGGGTAACGCAAATATTCTAAAGCTTCAATCCGCGCCGCTTCAT
CACGATCTTCAGGGTCTGCA

Downstream 100 bases:

>100_bases
ACGAACGTCCGATGTCGGCCGTGATTGAGGCGGCATCGTCCACCCGGCCCGCGCCGCCAGCGCTGGTAAACCGGCTTCAC
GGGTGGATCACCACTGTCGA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNMMGAPLALLFLANAAFAQTARPALSPTTIFSPVSTPADSIFHLSLFVLAVAAAIFTVVFSLLIYSLVRFRKRSDDDGR
EPPQIYGSNQVELAWTVVPILIVVTLFMATARVIAGTLKASRPSSSVEVVAVGHQFWWEFRYPGLKVVTANELHVPLSEP
GHPTPTFITLTSADTDHSFWVPRLAGKTDLIPNRVNTMWIDPHEPGLYLGQCAQYCGTQHAKMLLRVYVQTRDEFARWIQ
EQRQPAHAEDSVYAGRQIFETTACINCHTVTGTTAHGTFGPDLTHLMSRDTIASGAVPNSPENLRQWIRNPDAMKPGCRM
PAMNLGEREISAVAAYLETLR

Sequences:

>Translated_341_residues
MNMMGAPLALLFLANAAFAQTARPALSPTTIFSPVSTPADSIFHLSLFVLAVAAAIFTVVFSLLIYSLVRFRKRSDDDGR
EPPQIYGSNQVELAWTVVPILIVVTLFMATARVIAGTLKASRPSSSVEVVAVGHQFWWEFRYPGLKVVTANELHVPLSEP
GHPTPTFITLTSADTDHSFWVPRLAGKTDLIPNRVNTMWIDPHEPGLYLGQCAQYCGTQHAKMLLRVYVQTRDEFARWIQ
EQRQPAHAEDSVYAGRQIFETTACINCHTVTGTTAHGTFGPDLTHLMSRDTIASGAVPNSPENLRQWIRNPDAMKPGCRM
PAMNLGEREISAVAAYLETLR
>Mature_341_residues
MNMMGAPLALLFLANAAFAQTARPALSPTTIFSPVSTPADSIFHLSLFVLAVAAAIFTVVFSLLIYSLVRFRKRSDDDGR
EPPQIYGSNQVELAWTVVPILIVVTLFMATARVIAGTLKASRPSSSVEVVAVGHQFWWEFRYPGLKVVTANELHVPLSEP
GHPTPTFITLTSADTDHSFWVPRLAGKTDLIPNRVNTMWIDPHEPGLYLGQCAQYCGTQHAKMLLRVYVQTRDEFARWIQ
EQRQPAHAEDSVYAGRQIFETTACINCHTVTGTTAHGTFGPDLTHLMSRDTIASGAVPNSPENLRQWIRNPDAMKPGCRM
PAMNLGEREISAVAAYLETLR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=155, Percent_Identity=30.3225806451613, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1786635, Length=208, Percent_Identity=27.8846153846154, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6226540, Length=173, Percent_Identity=27.7456647398844, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 37675; Mature: 37675

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMMGAPLALLFLANAAFAQTARPALSPTTIFSPVSTPADSIFHLSLFVLAVAAAIFTVV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
FSLLIYSLVRFRKRSDDDGREPPQIYGSNQVELAWTVVPILIVVTLFMATARVIAGTLKA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRPSSSVEVVAVGHQFWWEFRYPGLKVVTANELHVPLSEPGHPTPTFITLTSADTDHSFW
CCCCCCEEEEEECHHHEEEEECCCEEEEECCCEECCCCCCCCCCCCEEEEEECCCCCCEE
VPRLAGKTDLIPNRVNTMWIDPHEPGLYLGQCAQYCGTQHAKMLLRVYVQTRDEFARWIQ
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EQRQPAHAEDSVYAGRQIFETTACINCHTVTGTTAHGTFGPDLTHLMSRDTIASGAVPNS
HHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PENLRQWIRNPDAMKPGCRMPAMNLGEREISAVAAYLETLR
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNMMGAPLALLFLANAAFAQTARPALSPTTIFSPVSTPADSIFHLSLFVLAVAAAIFTVV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
FSLLIYSLVRFRKRSDDDGREPPQIYGSNQVELAWTVVPILIVVTLFMATARVIAGTLKA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRPSSSVEVVAVGHQFWWEFRYPGLKVVTANELHVPLSEPGHPTPTFITLTSADTDHSFW
CCCCCCEEEEEECHHHEEEEECCCEEEEECCCEECCCCCCCCCCCCEEEEEECCCCCCEE
VPRLAGKTDLIPNRVNTMWIDPHEPGLYLGQCAQYCGTQHAKMLLRVYVQTRDEFARWIQ
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EQRQPAHAEDSVYAGRQIFETTACINCHTVTGTTAHGTFGPDLTHLMSRDTIASGAVPNS
HHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
PENLRQWIRNPDAMKPGCRMPAMNLGEREISAVAAYLETLR
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]