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The map label for this gene is pkn1 [H]

Identifier: 116626601

GI number: 116626601

Start: 9476850

End: 9477797

Strand: Direct

Name: pkn1 [H]

Synonym: Acid_7564

Alternate gene names: 116626601

Gene position: 9476850-9477797 (Clockwise)

Preceding gene: 116626600

Following gene: 116626602

Centisome position: 95.1

GC content: 63.61

Gene sequence:

>948_bases
ATGAACCTGGCCGGCGCACCGGCTCCCGGTATGATCCGGATACCAGGCGGGACGTTCCGCATGGGTTCCGAGGCCTTCTA
CCCGGAGGAGAGCCCGGTTCACGAAGTTGCGGTGGACGGCTTCTGGATCGACTGCCACGAAGTCACCAATCAGCGGTACG
GCGAATTCGTGGAAGCTACGGGCTATCTCACGGTCGCCGAGCGGCCGCTCAACGCCGCGGACTTTCCGGGTGCGCCTCCG
GAGAATCTCGTCCCGGGTTCGATGGTCTTTCGCAGAACCTCGGGGCCGGTTGACTTACACAACTACGTGAATTGGTGGGC
CTGGGTGCCGGGAGCGAGTTGGAAGCATCCGCAGGGTCCAGGCTCCTCGCTCGAAGGCATCGAACAGCACCCGGTGGTAC
ACGTCGCCTACGAAGATGCCGAGGCCTATGCGGGTTGGGCGGGCAAGGAACTGCCGACGGAGGCGGAGTGGGAATTCGCG
GCCCGCGGCGGGTTGGATGGCAAGAACTTTACCTGGGGCGATGAAGATTTCCCCGGCGGCAACGCGATGGCCAACAGCTG
GCAGGGGGAGTTTCCCTGGCAGAACCTCTTGGCAGACGGCTACGAAGGAACGTCTCCGGTCGGGTCATTTCCACCGAATG
GCTACGGGCTGTACGACATGGCGGGCAACGTATGGGAGTGGACCTCCGACTGGTTTGTTCCCCGGCACGCCGATGAAGTT
GTGCGCTCCTGCTGCGGTCCGGCGGTCAATCCGCGCATTTCGTCGCCTGCCAAGAGTTACGATCCAGCGCAGCCGCAGTT
TCAGATTCCGCGCAAAGTGGTCAAAGGCGGCTCGCACCTGTGCGCGCCCAACTATTGCCTGCGATACCGTCCGGCGGCCC
GCCAGCCGCAAATGCTCGATACCGGCATGACCCACATCGGCTTTCGCTGCATCGCTCGGGAGGCCTGA

Upstream 100 bases:

>100_bases
TGCCGGCACGCCGGGCAACGGCGGCGGACCCGATGAGGACGCTGCGGAGCGAATGAAGTCGCCCGCGCGCAGCTACTATT
GAATACAGGGAGGAGCTGTT

Downstream 100 bases:

>100_bases
AGAGCGCAAAAAATCCTGACTCTGCCGCCGGCCGGCGTCATCATGTCAGCGAATGGCATCACCCGAGGAGGTTCGAGGTT
TTTACGAACGCTATCCCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNLAGAPAPGMIRIPGGTFRMGSEAFYPEESPVHEVAVDGFWIDCHEVTNQRYGEFVEATGYLTVAERPLNAADFPGAPP
ENLVPGSMVFRRTSGPVDLHNYVNWWAWVPGASWKHPQGPGSSLEGIEQHPVVHVAYEDAEAYAGWAGKELPTEAEWEFA
ARGGLDGKNFTWGDEDFPGGNAMANSWQGEFPWQNLLADGYEGTSPVGSFPPNGYGLYDMAGNVWEWTSDWFVPRHADEV
VRSCCGPAVNPRISSPAKSYDPAQPQFQIPRKVVKGGSHLCAPNYCLRYRPAARQPQMLDTGMTHIGFRCIAREA

Sequences:

>Translated_315_residues
MNLAGAPAPGMIRIPGGTFRMGSEAFYPEESPVHEVAVDGFWIDCHEVTNQRYGEFVEATGYLTVAERPLNAADFPGAPP
ENLVPGSMVFRRTSGPVDLHNYVNWWAWVPGASWKHPQGPGSSLEGIEQHPVVHVAYEDAEAYAGWAGKELPTEAEWEFA
ARGGLDGKNFTWGDEDFPGGNAMANSWQGEFPWQNLLADGYEGTSPVGSFPPNGYGLYDMAGNVWEWTSDWFVPRHADEV
VRSCCGPAVNPRISSPAKSYDPAQPQFQIPRKVVKGGSHLCAPNYCLRYRPAARQPQMLDTGMTHIGFRCIAREA
>Mature_315_residues
MNLAGAPAPGMIRIPGGTFRMGSEAFYPEESPVHEVAVDGFWIDCHEVTNQRYGEFVEATGYLTVAERPLNAADFPGAPP
ENLVPGSMVFRRTSGPVDLHNYVNWWAWVPGASWKHPQGPGSSLEGIEQHPVVHVAYEDAEAYAGWAGKELPTEAEWEFA
ARGGLDGKNFTWGDEDFPGGNAMANSWQGEFPWQNLLADGYEGTSPVGSFPPNGYGLYDMAGNVWEWTSDWFVPRHADEV
VRSCCGPAVNPRISSPAKSYDPAQPQFQIPRKVVKGGSHLCAPNYCLRYRPAARQPQMLDTGMTHIGFRCIAREA

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=305, Percent_Identity=42.6229508196721, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI257470975, Length=306, Percent_Identity=40.8496732026144, Blast_Score=224, Evalue=5e-59,
Organism=Homo sapiens, GI257470977, Length=305, Percent_Identity=39.672131147541, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI194248088, Length=315, Percent_Identity=35.5555555555556, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI194248087, Length=315, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI194248090, Length=219, Percent_Identity=40.1826484018265, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI226437577, Length=211, Percent_Identity=38.8625592417062, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20130397, Length=311, Percent_Identity=38.2636655948553, Blast_Score=203, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 34617; Mature: 34617

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAGAPAPGMIRIPGGTFRMGSEAFYPEESPVHEVAVDGFWIDCHEVTNQRYGEFVEAT
CCCCCCCCCCEEECCCCCEECCCCCCCCCCCCHHEEEECCEEEEHHHHHHHHHHHHHHHC
GYLTVAERPLNAADFPGAPPENLVPGSMVFRRTSGPVDLHNYVNWWAWVPGASWKHPQGP
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEHHHHCEEEEECCCCCCCCCCCC
GSSLEGIEQHPVVHVAYEDAEAYAGWAGKELPTEAEWEFAARGGLDGKNFTWGDEDFPGG
CCCCCCHHHCCEEEEEECCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
NAMANSWQGEFPWQNLLADGYEGTSPVGSFPPNGYGLYDMAGNVWEWTSDWFVPRHADEV
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCHHHH
VRSCCGPAVNPRISSPAKSYDPAQPQFQIPRKVVKGGSHLCAPNYCLRYRPAARQPQMLD
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCEEECCCCCCCCHHHH
TGMTHIGFRCIAREA
HCHHHHCEEEEECCC
>Mature Secondary Structure
MNLAGAPAPGMIRIPGGTFRMGSEAFYPEESPVHEVAVDGFWIDCHEVTNQRYGEFVEAT
CCCCCCCCCCEEECCCCCEECCCCCCCCCCCCHHEEEECCEEEEHHHHHHHHHHHHHHHC
GYLTVAERPLNAADFPGAPPENLVPGSMVFRRTSGPVDLHNYVNWWAWVPGASWKHPQGP
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEHHHHCEEEEECCCCCCCCCCCC
GSSLEGIEQHPVVHVAYEDAEAYAGWAGKELPTEAEWEFAARGGLDGKNFTWGDEDFPGG
CCCCCCHHHCCEEEEEECCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
NAMANSWQGEFPWQNLLADGYEGTSPVGSFPPNGYGLYDMAGNVWEWTSDWFVPRHADEV
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCHHHH
VRSCCGPAVNPRISSPAKSYDPAQPQFQIPRKVVKGGSHLCAPNYCLRYRPAARQPQMLD
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCCEEECCCCCCCCHHHH
TGMTHIGFRCIAREA
HCHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]