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The map label for this gene is macB [H]

Identifier: 116626600

GI number: 116626600

Start: 9474130

End: 9476805

Strand: Direct

Name: macB [H]

Synonym: Acid_7563

Alternate gene names: 116626600

Gene position: 9474130-9476805 (Clockwise)

Preceding gene: 116626599

Following gene: 116626601

Centisome position: 95.07

GC content: 64.05

Gene sequence:

>2676_bases
ATGAGGATCCGGCGCTGGCTCGATATCGCGCGGCTGCGGCTGCGGTCGCTTTTCGGCAAGCGCCGGGTAGAGCAGGAACT
GGACCGTGAGCTGCGCTTTCACGTGGACCAACAGATTCAGGAAAGCATCGCCGGAGGAATGTCCGCGGAGGAAGCGCGAC
TGGCCGCGATGCGGCGTTTTGGAGGAGTGGTTCAAATCCAGGAGGAGTGCCGCGATATGCGCCGAATCAATCAGCTGGAG
ACTGTCGGGAACGACCTGCGCTACGCCGCACGGATGCTGGCGCGATCTCCGGGATTTACGGTGGTCATCATCATGACGCT
GGCCTTGAGCATCGGAGCCAACAGCGCGATCTTCAGCGTAATCGAAGGGGTGCTGCTGCGGCCGCTACCCTATGCGCAGC
CGGATAGTATTGCGCGGATTTTTCTGAACAGCGACACTTATCCGAAATTCCCGCTGAATCCCTTCGACTTCCGTGATTTT
CGCGCCCGTAACCGGGCCTTCGAGAGCATCGCCGGTATTACGCGGGGAGACATGCAACTCTCCGGGGCCGGCGAGCCGGT
GATGCTGCATGCTTTCCGGGTGACCGCAGGGTACTTCCGAGTGCTGGGTTTTGCGCCGGCGCGCGGGCGGGAGTTCACCA
CAGACGACGAACTACCCGGACACTTCCAGCAGGTGATTTTGAGCGACCGCATCTGGCGCGCGCAGTTTGCCTCCGACCCC
AACATCGTCGGCCGCCTGATCACGCTGGACGCGCGGAGTTTCACGGTGGTGGGGGTGATGCCGCCCGGAGCGCAGCACCC
CGGCAACGACTACCACGCGGTAGCCGACGGTGACAGCGTGGATCTCTGGTATCCATTCACGTTTGAAGGGAATCCGAACA
ATCGCGGCTCGCACTACCTGGAAGGGATCGGGCGTCTCAAAGCCGGCGTTTCACCGGAGCAGGGCAACGCGGACCTGAGC
GCGGTGCTGTCGCAACTGGCGACGGAACATCCCGGCGACAAAGGCTGGCGGGTGCTGGTGATTCCGCTCTATCGCGAACT
GGTAGGCCGCACGCAGCACATGCTGCTGGTATTGCTGTCCGCGGTCGGGCTGCTGTTGCTGATCGCATGCGTGAACGCGG
CGAACCTGCTGCTGGCGCGATCGAACGCGCGGCAGCGGGAGATTGCGGTACGGGCGGCGGTGGGCGCGGCGCGCTCGCGG
ATCGTGCGCCAACTACTGACGGAGAGTGTGTTGATCGCGCTCGCGGGGGCCGCGCTGGGGACGGCGCTGGCGGTGGGCGG
GGTGCGGGCGCTGGTATCCCTGCTGCCGCCGGGCTTTCCGCGAGCATCGGCGATCCATCTGGATGCAACGGTCTTTGCGT
TCACGCTTGCGATCGCCATGCTTACCGGACTGCTATTCGGAATCGTGCCGGCGCTGGCGGCGTCGCGGACGGATCTGCAG
ACGTGCCTGCGCGAAGGCGGCCGGGGCGCGACCGGCGGGCGACGCCAGCATCGATTGCGAGACCTGCTGGTGGTGGGTGA
GACCGGACTGGCGTGCGTTCTGTTGATTGCTGCGGGGTTGATGCTGCACAGTTTCGTCAACCTGCTGCGCGCCGACCCGG
GCTTCCGTCCGCAACAGGTTTTGACGGCATCGATCGCGCTGCCCGCGGAACAGTACAAGACTATGCCGGAGACGGAGCGG
TTCTGCGCACAACTGATCGCGAACCTGGAGGCAGTTCGCACGGTGCGATCGGCCGGAGTAGGAACCGACCTGCCCTGGAC
CGGCTATGACGAAAACGCCGGCGGCTTCACGGTGGAGGGCCGCCCGGCCGCGTACAACGATAAGACTACGGCGCGTTATC
ATGCCGCTTCACGGGACTACTTCCGCGCGTTGGGAGTCCCGCTGCTACGCGGCAGATTTTTTGCCGAGACCGATGATCTG
AAGGCGCCGAACGTGCTCTTGATCAATGAGACGATGGCCAAGCGGTATTGGCCCGGCGAAGATGCCGTTGGGAAACGGAT
CGCGTTCGACGACCATCCGAAAGAGAAGGATTGGATGCGGATTGTGGGCGTGGTGGGCGACGTTCGGGATCAGGCGACGA
GCGAGGCAGCGCATCCGGCATTCTGGTGGCCGCTCAAGCAGATGCCGTTTCCAATGCGAGCAATGTCCATAGTGATCCAC
ACCGAGGGCGATCCGGCGCTACTGGCCGGCCAATTGCGGCGCAGCGTGCAGCAACTCAACGCGGGATTGGCAGTGGCGGA
GCTCCGCGTGATGCAACAGATCGCCGACGAATCGGTTTCCACACAGAGGTTCGCGATGTTTCTGGTGGGTCTGTTCGCTG
GACTCGCGCTGGTGCTGGCGACCATCGGTATGTACGGCGTGATTTCGTACTCGGTGAATCAGCGGATGCATGAGTTCGGG
ATGCGGATGGCGCTGGGCGCGCGGCCGTGGGACGTGATGCGGCTGATTCTCGGGCAGGGAATGAAGCTATCGATTGCGGG
GTCGGCAATCGGTTTGGTGTGCGCGGCGGCGTTCGCGCGGCTGTTGGGAAGCTTGTTGTATGGAGTGCGCGGCATGGACC
CGGTGACATTCGCAGGGGTAACGCTGGTAGCGCTGGCGACGGCGACGCTGGCGTGTTACCTGCCGGCACGCCGGGCAACG
GCGGCGGACCCGATGAGGACGCTGCGGAGCGAATGA

Upstream 100 bases:

>100_bases
CCCGGGCAGGGCGGACCCAGCTGCAGAAAGAGCTGGAACAGTGGGAACGGCTCTCGGGCGCCGTTGGCCTTGTGATCCGG
ATGCTGCCGGAGGGTTCGGT

Downstream 100 bases:

>100_bases
AGTCGCCCGCGCGCAGCTACTATTGAATACAGGGAGGAGCTGTTATGAACCTGGCCGGCGCACCGGCTCCCGGTATGATC
CGGATACCAGGCGGGACGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 891

Protein sequence:

>891_residues
MRIRRWLDIARLRLRSLFGKRRVEQELDRELRFHVDQQIQESIAGGMSAEEARLAAMRRFGGVVQIQEECRDMRRINQLE
TVGNDLRYAARMLARSPGFTVVIIMTLALSIGANSAIFSVIEGVLLRPLPYAQPDSIARIFLNSDTYPKFPLNPFDFRDF
RARNRAFESIAGITRGDMQLSGAGEPVMLHAFRVTAGYFRVLGFAPARGREFTTDDELPGHFQQVILSDRIWRAQFASDP
NIVGRLITLDARSFTVVGVMPPGAQHPGNDYHAVADGDSVDLWYPFTFEGNPNNRGSHYLEGIGRLKAGVSPEQGNADLS
AVLSQLATEHPGDKGWRVLVIPLYRELVGRTQHMLLVLLSAVGLLLLIACVNAANLLLARSNARQREIAVRAAVGAARSR
IVRQLLTESVLIALAGAALGTALAVGGVRALVSLLPPGFPRASAIHLDATVFAFTLAIAMLTGLLFGIVPALAASRTDLQ
TCLREGGRGATGGRRQHRLRDLLVVGETGLACVLLIAAGLMLHSFVNLLRADPGFRPQQVLTASIALPAEQYKTMPETER
FCAQLIANLEAVRTVRSAGVGTDLPWTGYDENAGGFTVEGRPAAYNDKTTARYHAASRDYFRALGVPLLRGRFFAETDDL
KAPNVLLINETMAKRYWPGEDAVGKRIAFDDHPKEKDWMRIVGVVGDVRDQATSEAAHPAFWWPLKQMPFPMRAMSIVIH
TEGDPALLAGQLRRSVQQLNAGLAVAELRVMQQIADESVSTQRFAMFLVGLFAGLALVLATIGMYGVISYSVNQRMHEFG
MRMALGARPWDVMRLILGQGMKLSIAGSAIGLVCAAAFARLLGSLLYGVRGMDPVTFAGVTLVALATATLACYLPARRAT
AADPMRTLRSE

Sequences:

>Translated_891_residues
MRIRRWLDIARLRLRSLFGKRRVEQELDRELRFHVDQQIQESIAGGMSAEEARLAAMRRFGGVVQIQEECRDMRRINQLE
TVGNDLRYAARMLARSPGFTVVIIMTLALSIGANSAIFSVIEGVLLRPLPYAQPDSIARIFLNSDTYPKFPLNPFDFRDF
RARNRAFESIAGITRGDMQLSGAGEPVMLHAFRVTAGYFRVLGFAPARGREFTTDDELPGHFQQVILSDRIWRAQFASDP
NIVGRLITLDARSFTVVGVMPPGAQHPGNDYHAVADGDSVDLWYPFTFEGNPNNRGSHYLEGIGRLKAGVSPEQGNADLS
AVLSQLATEHPGDKGWRVLVIPLYRELVGRTQHMLLVLLSAVGLLLLIACVNAANLLLARSNARQREIAVRAAVGAARSR
IVRQLLTESVLIALAGAALGTALAVGGVRALVSLLPPGFPRASAIHLDATVFAFTLAIAMLTGLLFGIVPALAASRTDLQ
TCLREGGRGATGGRRQHRLRDLLVVGETGLACVLLIAAGLMLHSFVNLLRADPGFRPQQVLTASIALPAEQYKTMPETER
FCAQLIANLEAVRTVRSAGVGTDLPWTGYDENAGGFTVEGRPAAYNDKTTARYHAASRDYFRALGVPLLRGRFFAETDDL
KAPNVLLINETMAKRYWPGEDAVGKRIAFDDHPKEKDWMRIVGVVGDVRDQATSEAAHPAFWWPLKQMPFPMRAMSIVIH
TEGDPALLAGQLRRSVQQLNAGLAVAELRVMQQIADESVSTQRFAMFLVGLFAGLALVLATIGMYGVISYSVNQRMHEFG
MRMALGARPWDVMRLILGQGMKLSIAGSAIGLVCAAAFARLLGSLLYGVRGMDPVTFAGVTLVALATATLACYLPARRAT
AADPMRTLRSE
>Mature_891_residues
MRIRRWLDIARLRLRSLFGKRRVEQELDRELRFHVDQQIQESIAGGMSAEEARLAAMRRFGGVVQIQEECRDMRRINQLE
TVGNDLRYAARMLARSPGFTVVIIMTLALSIGANSAIFSVIEGVLLRPLPYAQPDSIARIFLNSDTYPKFPLNPFDFRDF
RARNRAFESIAGITRGDMQLSGAGEPVMLHAFRVTAGYFRVLGFAPARGREFTTDDELPGHFQQVILSDRIWRAQFASDP
NIVGRLITLDARSFTVVGVMPPGAQHPGNDYHAVADGDSVDLWYPFTFEGNPNNRGSHYLEGIGRLKAGVSPEQGNADLS
AVLSQLATEHPGDKGWRVLVIPLYRELVGRTQHMLLVLLSAVGLLLLIACVNAANLLLARSNARQREIAVRAAVGAARSR
IVRQLLTESVLIALAGAALGTALAVGGVRALVSLLPPGFPRASAIHLDATVFAFTLAIAMLTGLLFGIVPALAASRTDLQ
TCLREGGRGATGGRRQHRLRDLLVVGETGLACVLLIAAGLMLHSFVNLLRADPGFRPQQVLTASIALPAEQYKTMPETER
FCAQLIANLEAVRTVRSAGVGTDLPWTGYDENAGGFTVEGRPAAYNDKTTARYHAASRDYFRALGVPLLRGRFFAETDDL
KAPNVLLINETMAKRYWPGEDAVGKRIAFDDHPKEKDWMRIVGVVGDVRDQATSEAAHPAFWWPLKQMPFPMRAMSIVIH
TEGDPALLAGQLRRSVQQLNAGLAVAELRVMQQIADESVSTQRFAMFLVGLFAGLALVLATIGMYGVISYSVNQRMHEFG
MRMALGARPWDVMRLILGQGMKLSIAGSAIGLVCAAAFARLLGSLLYGVRGMDPVTFAGVTLVALATATLACYLPARRAT
AADPMRTLRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=290, Percent_Identity=27.9310344827586, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 97324; Mature: 97324

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRRWLDIARLRLRSLFGKRRVEQELDRELRFHVDQQIQESIAGGMSAEEARLAAMRRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GGVVQIQEECRDMRRINQLETVGNDLRYAARMLARSPGFTVVIIMTLALSIGANSAIFSV
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
IEGVLLRPLPYAQPDSIARIFLNSDTYPKFPLNPFDFRDFRARNRAFESIAGITRGDMQL
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
SGAGEPVMLHAFRVTAGYFRVLGFAPARGREFTTDDELPGHFQQVILSDRIWRAQFASDP
CCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NIVGRLITLDARSFTVVGVMPPGAQHPGNDYHAVADGDSVDLWYPFTFEGNPNNRGSHYL
CCEEEEEEEECCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCCCHHHH
EGIGRLKAGVSPEQGNADLSAVLSQLATEHPGDKGWRVLVIPLYRELVGRTQHMLLVLLS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
AVGLLLLIACVNAANLLLARSNARQREIAVRAAVGAARSRIVRQLLTESVLIALAGAALG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALAVGGVRALVSLLPPGFPRASAIHLDATVFAFTLAIAMLTGLLFGIVPALAASRTDLQ
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TCLREGGRGATGGRRQHRLRDLLVVGETGLACVLLIAAGLMLHSFVNLLRADPGFRPQQV
HHHHCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LTASIALPAEQYKTMPETERFCAQLIANLEAVRTVRSAGVGTDLPWTGYDENAGGFTVEG
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECC
RPAAYNDKTTARYHAASRDYFRALGVPLLRGRFFAETDDLKAPNVLLINETMAKRYWPGE
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCC
DAVGKRIAFDDHPKEKDWMRIVGVVGDVRDQATSEAAHPAFWWPLKQMPFPMRAMSIVIH
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHCCCCCEEEEEEEE
TEGDPALLAGQLRRSVQQLNAGLAVAELRVMQQIADESVSTQRFAMFLVGLFAGLALVLA
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TIGMYGVISYSVNQRMHEFGMRMALGARPWDVMRLILGQGMKLSIAGSAIGLVCAAAFAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
LLGSLLYGVRGMDPVTFAGVTLVALATATLACYLPARRATAADPMRTLRSE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHCC
>Mature Secondary Structure
MRIRRWLDIARLRLRSLFGKRRVEQELDRELRFHVDQQIQESIAGGMSAEEARLAAMRRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GGVVQIQEECRDMRRINQLETVGNDLRYAARMLARSPGFTVVIIMTLALSIGANSAIFSV
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
IEGVLLRPLPYAQPDSIARIFLNSDTYPKFPLNPFDFRDFRARNRAFESIAGITRGDMQL
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
SGAGEPVMLHAFRVTAGYFRVLGFAPARGREFTTDDELPGHFQQVILSDRIWRAQFASDP
CCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NIVGRLITLDARSFTVVGVMPPGAQHPGNDYHAVADGDSVDLWYPFTFEGNPNNRGSHYL
CCEEEEEEEECCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCCCHHHH
EGIGRLKAGVSPEQGNADLSAVLSQLATEHPGDKGWRVLVIPLYRELVGRTQHMLLVLLS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
AVGLLLLIACVNAANLLLARSNARQREIAVRAAVGAARSRIVRQLLTESVLIALAGAALG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALAVGGVRALVSLLPPGFPRASAIHLDATVFAFTLAIAMLTGLLFGIVPALAASRTDLQ
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TCLREGGRGATGGRRQHRLRDLLVVGETGLACVLLIAAGLMLHSFVNLLRADPGFRPQQV
HHHHCCCCCCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LTASIALPAEQYKTMPETERFCAQLIANLEAVRTVRSAGVGTDLPWTGYDENAGGFTVEG
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECC
RPAAYNDKTTARYHAASRDYFRALGVPLLRGRFFAETDDLKAPNVLLINETMAKRYWPGE
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCC
DAVGKRIAFDDHPKEKDWMRIVGVVGDVRDQATSEAAHPAFWWPLKQMPFPMRAMSIVIH
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHCCCCCEEEEEEEE
TEGDPALLAGQLRRSVQQLNAGLAVAELRVMQQIADESVSTQRFAMFLVGLFAGLALVLA
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TIGMYGVISYSVNQRMHEFGMRMALGARPWDVMRLILGQGMKLSIAGSAIGLVCAAAFAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
LLGSLLYGVRGMDPVTFAGVTLVALATATLACYLPARRATAADPMRTLRSE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]