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The map label for this gene is flhA [H]

Identifier: 116626502

GI number: 116626502

Start: 9353957

End: 9356056

Strand: Direct

Name: flhA [H]

Synonym: Acid_7465

Alternate gene names: 116626502

Gene position: 9353957-9356056 (Clockwise)

Preceding gene: 116626501

Following gene: 116626503

Centisome position: 93.86

GC content: 63.76

Gene sequence:

>2100_bases
GTGACCCCATCCAAAGCCATCACCGCTCCCAAGCTCCCCGGGGATTGGCCCGATTGGGTCAAGAGCCTGCCGCTCGACAC
CCTGGGCCAGTTGGCGGTTCCTCTGGCGGTATTGGCGATCGTGATCGCATTGATCACGCCGCTGCCGGGGTTCCTGCTGG
ACCTGTTGATCGTGGTGGACATCCTGGTTTCGGTAACGGTGCTGATGGTGTCGCTCTACCTCGTCCGGCCGGTGGAGTTC
ACATCATTTCCAACGACGCTTTTGCTTTTGACGTTGTTCCGTCTGGCGCTGAACGTCTCCAGTTCTCGGCTGATTCTGCT
CAACGGAAATACCGGGACGGCGGCGGCCGGGGAAGTGATCGGCGCGTTCGGCAGCTTTGTGGTGGGCGGCAACTACGTGA
TCGGCGCGGTAATTTTCCTGGTACTGATCGCCATTCAATATGTCGTCATCAATCACGGCGCGGTCCGCATCAGCGAAGTC
ACGGCGCGATTTACCCTGGATGCGCTGCCCGGCAAACAGATGTCGATCGACGGCGATCTGAACGCGGGTTTGATCGACGA
GGCGGAGGCCAAGCGGCGGCGCAAGGCGCTCGCTACCGAGGCCGAATTCTATGGCGCGATGGATGGCGCTTCGCGTTTCA
CGCAGCGCGACGCGGTGGCGAGCATCCTGATCACCGCGATCAACATCATCGCCGGCTTCCTGATCGGTGTCACGCAGCAT
GGAATGGACTTCCGCCGCGCGCTCGAAACCTACACGGTGCTGACCATCGGGGATGGTCTGGTCACGGTGATTCCGGCGCT
GATGATCTCCATTTCGGGAGGCCTGATCGTCACGCGCGCAAGCTCGGAGGCCCGGCTCGGCGCGGAATTCCACAAGCAGA
TTCTCGGTAACTCACAGCCGTTGTTGCTCGCTGCCGGAGTGCTGGTTGCCCTGGCGGCGCTGCCCGGCATGCCCAAACTC
CCGTTCCTGGTGCTGGGGTTCGGGGCCGGAGCCGGCGGATGGCGAATGCGTAAAACGGAACTGGCGCAGATTGCCGCGCC
CCCGGAGGATACGGGCAAGCCGGCGCCCGCCAAGGACAGCGTGGAATCGCTGCTGCGTGTGGAACCGCTGGCGATCGAAG
TGGGACTGGGGCTGATCGGCCTGGTGGAAGGCGCGCAGGAGTCGCCGTTGCTCCGGCGGATCTCGGCAATCCGCCGGCAA
CTGGCCACCGACCTCGGGTACCTTCTGCCCCCGGTGCGGGTGACCGACAACCTGTCACTGCGCAGCCGGGAATACGTGAT
TTCGCTGAAAGGCGTCGAGATCGCGCGCTACGAATTGCCGCAGGGCTGTGAGCTGGCGATTGCCACCGGCGCCGCGAGCG
CTCCGCTGGAAGGCCAGGCGACGCGCGACCCGGCCTTCGGTATGAACGCCACCTGGATTCCCGCCGACCGCGCGGACCGG
GCGCGGCATTCGGGATATACCGTGGTCGATAGCGTGAGCGTGCTGGGAACTCACCTCTCGGAAATTATCAGGCGATACGC
GCATGAATTGTTCTCGCGTCAGGACGCCAAGCGGCTCCTGGACCGGGTCGGGGTGGAGCATCCCAAGGTCGTGGAAGACG
TGGTGCCGAAGCTCCTGCCGCTCTCCAGCGTACAGCGCGTGCTGCAGAATCTCTTGCGCGAGCGGGTATCGATCCGCGAC
GCAGTCTCGATTCTGGAGGCCCTGGGCGAGGCCGGCGCGTCGACTCGGAACCCCATCCTGCTCACCGAGTATGTGCGCCA
GGCCATCCGGCGCGCAGTCGTAAAACCGTATCTCAACCGGGCAGGCGATCTGCCGGCCTGGTTCGTGGATCCGGCGATAG
AGCATGCCGTGGAAGCGGCCGTGGAACACGGCGAACAGAACAGCCACATTCAACTGGCGCCGCAGCACATTCGCGAGATG
CTCAACCGGATTTCGGCGCGAATTCAGTCGCCGGAGACGCCAGTGGTGGCGATCACTTCGAGCGGAGCGCGCTACTTCCT
GCGGCAGATCGCGGAGCCCACGATGCCCAACCTGTTCTTCCTGGCGCACAACGAAGTTCCACCCGGAGTGCGGGTTCAGT
CACTAGGCAATATTCAGTAG

Upstream 100 bases:

>100_bases
GTCGAGGTCGGGCAGGAAATTCCTCCGCACCTCTACCGCGCGGTAGCCGAGATCCTGGCATACATCTTCAAACTGATGAA
CGGAAGGATGCCCGGCTAGC

Downstream 100 bases:

>100_bases
CAGTCGCCCTACAGAGAATCGTCGGACCCGCCGATAGATGCGGGAGAGACGACCCTGTGTGGACCGGTGAGCGACCGCGA
TGAAAATCAAATCCTACTAT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MTPSKAITAPKLPGDWPDWVKSLPLDTLGQLAVPLAVLAIVIALITPLPGFLLDLLIVVDILVSVTVLMVSLYLVRPVEF
TSFPTTLLLLTLFRLALNVSSSRLILLNGNTGTAAAGEVIGAFGSFVVGGNYVIGAVIFLVLIAIQYVVINHGAVRISEV
TARFTLDALPGKQMSIDGDLNAGLIDEAEAKRRRKALATEAEFYGAMDGASRFTQRDAVASILITAINIIAGFLIGVTQH
GMDFRRALETYTVLTIGDGLVTVIPALMISISGGLIVTRASSEARLGAEFHKQILGNSQPLLLAAGVLVALAALPGMPKL
PFLVLGFGAGAGGWRMRKTELAQIAAPPEDTGKPAPAKDSVESLLRVEPLAIEVGLGLIGLVEGAQESPLLRRISAIRRQ
LATDLGYLLPPVRVTDNLSLRSREYVISLKGVEIARYELPQGCELAIATGAASAPLEGQATRDPAFGMNATWIPADRADR
ARHSGYTVVDSVSVLGTHLSEIIRRYAHELFSRQDAKRLLDRVGVEHPKVVEDVVPKLLPLSSVQRVLQNLLRERVSIRD
AVSILEALGEAGASTRNPILLTEYVRQAIRRAVVKPYLNRAGDLPAWFVDPAIEHAVEAAVEHGEQNSHIQLAPQHIREM
LNRISARIQSPETPVVAITSSGARYFLRQIAEPTMPNLFFLAHNEVPPGVRVQSLGNIQ

Sequences:

>Translated_699_residues
MTPSKAITAPKLPGDWPDWVKSLPLDTLGQLAVPLAVLAIVIALITPLPGFLLDLLIVVDILVSVTVLMVSLYLVRPVEF
TSFPTTLLLLTLFRLALNVSSSRLILLNGNTGTAAAGEVIGAFGSFVVGGNYVIGAVIFLVLIAIQYVVINHGAVRISEV
TARFTLDALPGKQMSIDGDLNAGLIDEAEAKRRRKALATEAEFYGAMDGASRFTQRDAVASILITAINIIAGFLIGVTQH
GMDFRRALETYTVLTIGDGLVTVIPALMISISGGLIVTRASSEARLGAEFHKQILGNSQPLLLAAGVLVALAALPGMPKL
PFLVLGFGAGAGGWRMRKTELAQIAAPPEDTGKPAPAKDSVESLLRVEPLAIEVGLGLIGLVEGAQESPLLRRISAIRRQ
LATDLGYLLPPVRVTDNLSLRSREYVISLKGVEIARYELPQGCELAIATGAASAPLEGQATRDPAFGMNATWIPADRADR
ARHSGYTVVDSVSVLGTHLSEIIRRYAHELFSRQDAKRLLDRVGVEHPKVVEDVVPKLLPLSSVQRVLQNLLRERVSIRD
AVSILEALGEAGASTRNPILLTEYVRQAIRRAVVKPYLNRAGDLPAWFVDPAIEHAVEAAVEHGEQNSHIQLAPQHIREM
LNRISARIQSPETPVVAITSSGARYFLRQIAEPTMPNLFFLAHNEVPPGVRVQSLGNIQ
>Mature_698_residues
TPSKAITAPKLPGDWPDWVKSLPLDTLGQLAVPLAVLAIVIALITPLPGFLLDLLIVVDILVSVTVLMVSLYLVRPVEFT
SFPTTLLLLTLFRLALNVSSSRLILLNGNTGTAAAGEVIGAFGSFVVGGNYVIGAVIFLVLIAIQYVVINHGAVRISEVT
ARFTLDALPGKQMSIDGDLNAGLIDEAEAKRRRKALATEAEFYGAMDGASRFTQRDAVASILITAINIIAGFLIGVTQHG
MDFRRALETYTVLTIGDGLVTVIPALMISISGGLIVTRASSEARLGAEFHKQILGNSQPLLLAAGVLVALAALPGMPKLP
FLVLGFGAGAGGWRMRKTELAQIAAPPEDTGKPAPAKDSVESLLRVEPLAIEVGLGLIGLVEGAQESPLLRRISAIRRQL
ATDLGYLLPPVRVTDNLSLRSREYVISLKGVEIARYELPQGCELAIATGAASAPLEGQATRDPAFGMNATWIPADRADRA
RHSGYTVVDSVSVLGTHLSEIIRRYAHELFSRQDAKRLLDRVGVEHPKVVEDVVPKLLPLSSVQRVLQNLLRERVSIRDA
VSILEALGEAGASTRNPILLTEYVRQAIRRAVVKPYLNRAGDLPAWFVDPAIEHAVEAAVEHGEQNSHIQLAPQHIREML
NRISARIQSPETPVVAITSSGARYFLRQIAEPTMPNLFFLAHNEVPPGVRVQSLGNIQ

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=661, Percent_Identity=43.5703479576399, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75139; Mature: 75007

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSKAITAPKLPGDWPDWVKSLPLDTLGQLAVPLAVLAIVIALITPLPGFLLDLLIVVD
CCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ILVSVTVLMVSLYLVRPVEFTSFPTTLLLLTLFRLALNVSSSRLILLNGNTGTAAAGEVI
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
GAFGSFVVGGNYVIGAVIFLVLIAIQYVVINHGAVRISEVTARFTLDALPGKQMSIDGDL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHEEECCCCCCEEECCCC
NAGLIDEAEAKRRRKALATEAEFYGAMDGASRFTQRDAVASILITAINIIAGFLIGVTQH
CCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDFRRALETYTVLTIGDGLVTVIPALMISISGGLIVTRASSEARLGAEFHKQILGNSQP
CHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
LLLAAGVLVALAALPGMPKLPFLVLGFGAGAGGWRMRKTELAQIAAPPEDTGKPAPAKDS
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
VESLLRVEPLAIEVGLGLIGLVEGAQESPLLRRISAIRRQLATDLGYLLPPVRVTDNLSL
HHHHHHCCCHHEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
RSREYVISLKGVEIARYELPQGCELAIATGAASAPLEGQATRDPAFGMNATWIPADRADR
CCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCHHHH
ARHSGYTVVDSVSVLGTHLSEIIRRYAHELFSRQDAKRLLDRVGVEHPKVVEDVVPKLLP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
LSSVQRVLQNLLRERVSIRDAVSILEALGEAGASTRNPILLTEYVRQAIRRAVVKPYLNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
AGDLPAWFVDPAIEHAVEAAVEHGEQNSHIQLAPQHIREMLNRISARIQSPETPVVAITS
CCCCCHHHHCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEEEEC
SGARYFLRQIAEPTMPNLFFLAHNEVPPGVRVQSLGNIQ
CCHHHHHHHHCCCCCCCEEEEECCCCCCCCEECCCCCCC
>Mature Secondary Structure 
TPSKAITAPKLPGDWPDWVKSLPLDTLGQLAVPLAVLAIVIALITPLPGFLLDLLIVVD
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ILVSVTVLMVSLYLVRPVEFTSFPTTLLLLTLFRLALNVSSSRLILLNGNTGTAAAGEVI
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
GAFGSFVVGGNYVIGAVIFLVLIAIQYVVINHGAVRISEVTARFTLDALPGKQMSIDGDL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHEEECCCCCCEEECCCC
NAGLIDEAEAKRRRKALATEAEFYGAMDGASRFTQRDAVASILITAINIIAGFLIGVTQH
CCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDFRRALETYTVLTIGDGLVTVIPALMISISGGLIVTRASSEARLGAEFHKQILGNSQP
CHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
LLLAAGVLVALAALPGMPKLPFLVLGFGAGAGGWRMRKTELAQIAAPPEDTGKPAPAKDS
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHH
VESLLRVEPLAIEVGLGLIGLVEGAQESPLLRRISAIRRQLATDLGYLLPPVRVTDNLSL
HHHHHHCCCHHEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
RSREYVISLKGVEIARYELPQGCELAIATGAASAPLEGQATRDPAFGMNATWIPADRADR
CCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCHHHH
ARHSGYTVVDSVSVLGTHLSEIIRRYAHELFSRQDAKRLLDRVGVEHPKVVEDVVPKLLP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
LSSVQRVLQNLLRERVSIRDAVSILEALGEAGASTRNPILLTEYVRQAIRRAVVKPYLNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
AGDLPAWFVDPAIEHAVEAAVEHGEQNSHIQLAPQHIREMLNRISARIQSPETPVVAITS
CCCCCHHHHCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEEEEC
SGARYFLRQIAEPTMPNLFFLAHNEVPPGVRVQSLGNIQ
CCHHHHHHHHCCCCCCCEEEEECCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]