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The map label for this gene is argE [H]

Identifier: 116626026

GI number: 116626026

Start: 8772136

End: 8773155

Strand: Reverse

Name: argE [H]

Synonym: Acid_6984

Alternate gene names: 116626026

Gene position: 8773155-8772136 (Counterclockwise)

Preceding gene: 116626028

Following gene: 116626025

Centisome position: 88.03

GC content: 62.55

Gene sequence:

>1020_bases
ATGAACGTCTTCGAACTCACGCGAGCGCTGGTCGATATCGAATCGATCACAAATAATGAAGAGCGCGTAGGATTGTACCT
GCGCGATTACCTGACTCCGCTCGCAGCGCGGTACGGCGGCGCGATCGAGACGATCGAGGTAGAGCCGCGACGGTTCAATA
TTTTCGTGCAATTCGGCGCGCCGCTGATGGTCACGCTTTCGACGCACATCGACACAGTTCCGCCGTTCATCGCTTCGCGG
GAAGACGATACCTACATCTGGGGGCGCGGCGCGTGCGACACGAAGGGCATCATCGCCAGCATGATCAAGGCGGTGGAGGC
GCTGCTCGAGGCGGGGGAGCGCGGCTTCGGGCTGCTGTTCGTGGTCGGCGAAGAGCGCAATAGCGCGGGAGCTTACAAAG
CGGCGCAGACGCCACGCGGATCGCGGTACATCATCAACGGGGAGCCGACCGAGAACCAACTCGCGCTGGGTAGCAAGGGG
GCGCTGCGCTACGAGGTGTGGACCTCGGGCAAGATGGCACACTCGGCGTATCCCGAGTTGGGTGAATCGGCGATCAACAA
GCTGCTGGACGTGTTGGCCGACATACGGCGCATCCCGCTGCCAGTGGATGAGCTGCTGGGGCCGAGCACATTGAATATCG
GCACGCTCTCGGGAGGGCGCGCGCCCAACGTGATCGCAGACGAGGCCAGGGCGGATATCATGATCCGGCTGGTGGGCGAT
CCGGCGGAAACCAAGGCGGCGTTGTTCCGGGCGGCCGAGGGGCGCGCCGAGCTGCGGGAAGTCATCGAAATTCCGGCGGT
CCGGCTGGGCGCGGTGGACGGGATTCCGACTACCGTAGTGGCCTTCACCACCGATATTCCTGCGTTCGGCGGCGAGTGGG
GAGAGCCGCTGTTGATCGGACCGGGGACTATTCACGTCGCGCACACGCTGGAAGAGCGGGTGCCGAAGACCCAGCTTCTG
GAAGCTGTGGAACTTTATCAGCGCATCATAAAGGATTTATGCAAACGCGAATCGAAGTAG

Upstream 100 bases:

>100_bases
TCACCCGTTCACAGGCGGGTGGAGCGCTATCGGGATTGACGACGCGTAGCAGCATGCGCGGCCTCTCCTTCTCGTTGCAT
TCCCCCCAAACGGACAATTT

Downstream 100 bases:

>100_bases
GCATTCTCGGCGCCACCGGGATGGTGGGCCAGCATTTCATCAAGTTCCTGCAGGGCCACCCGTGGTTCGACCTGAAGTGG
CTCGGAGCCAGCGACCGCTC

Product: peptidase dimerisation domain-containing protein

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNVFELTRALVDIESITNNEERVGLYLRDYLTPLAARYGGAIETIEVEPRRFNIFVQFGAPLMVTLSTHIDTVPPFIASR
EDDTYIWGRGACDTKGIIASMIKAVEALLEAGERGFGLLFVVGEERNSAGAYKAAQTPRGSRYIINGEPTENQLALGSKG
ALRYEVWTSGKMAHSAYPELGESAINKLLDVLADIRRIPLPVDELLGPSTLNIGTLSGGRAPNVIADEARADIMIRLVGD
PAETKAALFRAAEGRAELREVIEIPAVRLGAVDGIPTTVVAFTTDIPAFGGEWGEPLLIGPGTIHVAHTLEERVPKTQLL
EAVELYQRIIKDLCKRESK

Sequences:

>Translated_339_residues
MNVFELTRALVDIESITNNEERVGLYLRDYLTPLAARYGGAIETIEVEPRRFNIFVQFGAPLMVTLSTHIDTVPPFIASR
EDDTYIWGRGACDTKGIIASMIKAVEALLEAGERGFGLLFVVGEERNSAGAYKAAQTPRGSRYIINGEPTENQLALGSKG
ALRYEVWTSGKMAHSAYPELGESAINKLLDVLADIRRIPLPVDELLGPSTLNIGTLSGGRAPNVIADEARADIMIRLVGD
PAETKAALFRAAEGRAELREVIEIPAVRLGAVDGIPTTVVAFTTDIPAFGGEWGEPLLIGPGTIHVAHTLEERVPKTQLL
EAVELYQRIIKDLCKRESK
>Mature_339_residues
MNVFELTRALVDIESITNNEERVGLYLRDYLTPLAARYGGAIETIEVEPRRFNIFVQFGAPLMVTLSTHIDTVPPFIASR
EDDTYIWGRGACDTKGIIASMIKAVEALLEAGERGFGLLFVVGEERNSAGAYKAAQTPRGSRYIINGEPTENQLALGSKG
ALRYEVWTSGKMAHSAYPELGESAINKLLDVLADIRRIPLPVDELLGPSTLNIGTLSGGRAPNVIADEARADIMIRLVGD
PAETKAALFRAAEGRAELREVIEIPAVRLGAVDGIPTTVVAFTTDIPAFGGEWGEPLLIGPGTIHVAHTLEERVPKTQLL
EAVELYQRIIKDLCKRESK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=374, Percent_Identity=26.7379679144385, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789236, Length=227, Percent_Identity=26.8722466960352, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=299, Percent_Identity=33.7792642140468, Blast_Score=164, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 36892; Mature: 36892

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFELTRALVDIESITNNEERVGLYLRDYLTPLAARYGGAIETIEVEPRRFNIFVQFGA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECC
PLMVTLSTHIDTVPPFIASREDDTYIWGRGACDTKGIIASMIKAVEALLEAGERGFGLLF
CEEEEEECCCCCCCCHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VVGEERNSAGAYKAAQTPRGSRYIINGEPTENQLALGSKGALRYEVWTSGKMAHSAYPEL
EEECCCCCCCCEECCCCCCCCEEEECCCCCCCCEEECCCCCEEEEEECCCCCCHHCCHHH
GESAINKLLDVLADIRRIPLPVDELLGPSTLNIGTLSGGRAPNVIADEARADIMIRLVGD
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCHHHCCCCEEEEEEECC
PAETKAALFRAAEGRAELREVIEIPAVRLGAVDGIPTTVVAFTTDIPAFGGEWGEPLLIG
CHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCEEEEC
PGTIHVAHTLEERVPKTQLLEAVELYQRIIKDLCKRESK
CCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVFELTRALVDIESITNNEERVGLYLRDYLTPLAARYGGAIETIEVEPRRFNIFVQFGA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECC
PLMVTLSTHIDTVPPFIASREDDTYIWGRGACDTKGIIASMIKAVEALLEAGERGFGLLF
CEEEEEECCCCCCCCHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
VVGEERNSAGAYKAAQTPRGSRYIINGEPTENQLALGSKGALRYEVWTSGKMAHSAYPEL
EEECCCCCCCCEECCCCCCCCEEEECCCCCCCCEEECCCCCEEEEEECCCCCCHHCCHHH
GESAINKLLDVLADIRRIPLPVDELLGPSTLNIGTLSGGRAPNVIADEARADIMIRLVGD
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCHHHCCCCEEEEEEECC
PAETKAALFRAAEGRAELREVIEIPAVRLGAVDGIPTTVVAFTTDIPAFGGEWGEPLLIG
CHHHHHHHHHHHCCHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCEEEEC
PGTIHVAHTLEERVPKTQLLEAVELYQRIIKDLCKRESK
CCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]