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The map label for this gene is 116626003

Identifier: 116626003

GI number: 116626003

Start: 8750324

End: 8751847

Strand: Reverse

Name: 116626003

Synonym: Acid_6961

Alternate gene names: NA

Gene position: 8751847-8750324 (Counterclockwise)

Preceding gene: 116626004

Following gene: 116626002

Centisome position: 87.82

GC content: 62.14

Gene sequence:

>1524_bases
ATGCCAAAGACAATTGATGTAACCGAACTCGTTCTCCGCGACGGCCACCAGAGCCTGATGGCCACGCGGATGGCAATGGA
AGACATGATTCCCGCCTGCGCGGATATCGACCAGGCGGGCTACTGGTCGGTGGAGTGCTGGGGAGGCGCGACCTTCGACT
CCTGCATCCGTTTCCTCAATGAGGATCCGTGGGAGCGCCTGCGGCAGTTCCGCAAGCTGCTGCCGAACAGCCGCCTCCAG
ATGCTGCTGCGCGGCCAGAATCTTCTTGGTTATCGCCACTATGAGGATTCCGTGGTGGACCGGTTTGTCGATAAGGCCGC
CGAAAACGGCATGGACGTCTTCCGTGTGTTCGATGCCCTCAACGACATACGGAATCTGCGCCGCTCGATCGCGGCGGTCC
GCCGCACCGGAAAGCATGCGCAAGGCACAATCTGCTACACGGTGAGCCCGCTGCACACGCCCGGCGACTTCGTCGAAATG
GCGGAGAAACTGCTCGAACTGGGCTGCGACTCCATCTGCATCAAAGATATGGCGGCGCTTCTCAAGCCGCAGGCGGCGTT
CGATATCGTCCAGGGAATCAAGGAGACTTGCGGGCAGAACACGCGGGTCCACGTCCACGTCCACGCCACCACCGGCGTCA
CTCTCGTCAGCCTGATGAAGGCCATCGAAGCCGGCGCGGACTGCGTCGATACGTGTATCAGTTCGCTGAGTTTGGGGCCG
GGACACAACCCCACCGAGAGCCTGGTCGAGATGCTCGACGGCACGGGTTTTGAAACCAAGCTGGATCGCAAGCGCCTGAT
CAGTATCAAGAAGTACTTCGCCGGGATTCGTCCGCGCTACCAGGAGTTCCTCTCCAATATCACGGGGGTGGAGACCGAGA
TCTTCGCCAGCCAGATTCCCGGCGGCATGCTCTCGAACATGGAGAGCCAGCTCAAGCAGCAGGGGGCGGGCGACCGTATG
GAGGAGGTACTGCTCGAAGTGCCCAAGGTCCGGGCCGACGCCGGCTTCCCGCCGCTGGTGACGCCTTCCAGCCAAATCGT
CGGCACACAGGCCGTTTTCAACGTCATGATGGGGCGCTACAAAGTCATGACCGGCGAATTCGCCGACCTCATGTTGGGCT
ATTACGGCGAAACTATCGGACCGCGGGACCCGGCCGTGATCGCGCAGGCCCACAAGCAGACCGGCAAGAACCCGATCAAC
GGCCGGCCGGCCGACCTGCTGAAGCCCGAGTGGCATGAACTCCGCGACGCCGCGGTGGCGCTCGAGGGGTGCAATGGAAC
CGATGAGGACGTGCTGACTTACGCCATGTTCCCGAAGGTGGCGCCCACCTTCTTCCCGGCACGCGCCCGGGGCCCCAAGA
ACTTAGGCAAGGATCCGGTTGCCCATCCGGCCGCCGCCACTGCTGCAGCTCCCGTCAAATCCGGCCCCGCCGATAGCGGC
AAAGGGCCGGTAACAACCACCATCACCTACGACGTGAAATATAACGGCAAAACGCACAAGGTAACCGTGGCGGCCTGTAA
GTAA

Upstream 100 bases:

>100_bases
ATCATCCTACAAAATGAAGACCTTTACCATTCACTGGCATCCCTCTCTTTCAAGCTGGAAAGCAAATTGGGAGTAAGCCC
GGTGGAAAACGGAACCTGCT

Downstream 100 bases:

>100_bases
CTATCGAAGTAAGTACTCATAAAAGGAACCCATATGGCCATTCATACAATGCAGGAAAAGGTTGCCGAGCTCCATGAGCG
CACCAGCAAAGCCATGCTGG

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: Transcarboxylase 5S subunit [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MPKTIDVTELVLRDGHQSLMATRMAMEDMIPACADIDQAGYWSVECWGGATFDSCIRFLNEDPWERLRQFRKLLPNSRLQ
MLLRGQNLLGYRHYEDSVVDRFVDKAAENGMDVFRVFDALNDIRNLRRSIAAVRRTGKHAQGTICYTVSPLHTPGDFVEM
AEKLLELGCDSICIKDMAALLKPQAAFDIVQGIKETCGQNTRVHVHVHATTGVTLVSLMKAIEAGADCVDTCISSLSLGP
GHNPTESLVEMLDGTGFETKLDRKRLISIKKYFAGIRPRYQEFLSNITGVETEIFASQIPGGMLSNMESQLKQQGAGDRM
EEVLLEVPKVRADAGFPPLVTPSSQIVGTQAVFNVMMGRYKVMTGEFADLMLGYYGETIGPRDPAVIAQAHKQTGKNPIN
GRPADLLKPEWHELRDAAVALEGCNGTDEDVLTYAMFPKVAPTFFPARARGPKNLGKDPVAHPAAATAAAPVKSGPADSG
KGPVTTTITYDVKYNGKTHKVTVAACK

Sequences:

>Translated_507_residues
MPKTIDVTELVLRDGHQSLMATRMAMEDMIPACADIDQAGYWSVECWGGATFDSCIRFLNEDPWERLRQFRKLLPNSRLQ
MLLRGQNLLGYRHYEDSVVDRFVDKAAENGMDVFRVFDALNDIRNLRRSIAAVRRTGKHAQGTICYTVSPLHTPGDFVEM
AEKLLELGCDSICIKDMAALLKPQAAFDIVQGIKETCGQNTRVHVHVHATTGVTLVSLMKAIEAGADCVDTCISSLSLGP
GHNPTESLVEMLDGTGFETKLDRKRLISIKKYFAGIRPRYQEFLSNITGVETEIFASQIPGGMLSNMESQLKQQGAGDRM
EEVLLEVPKVRADAGFPPLVTPSSQIVGTQAVFNVMMGRYKVMTGEFADLMLGYYGETIGPRDPAVIAQAHKQTGKNPIN
GRPADLLKPEWHELRDAAVALEGCNGTDEDVLTYAMFPKVAPTFFPARARGPKNLGKDPVAHPAAATAAAPVKSGPADSG
KGPVTTTITYDVKYNGKTHKVTVAACK
>Mature_506_residues
PKTIDVTELVLRDGHQSLMATRMAMEDMIPACADIDQAGYWSVECWGGATFDSCIRFLNEDPWERLRQFRKLLPNSRLQM
LLRGQNLLGYRHYEDSVVDRFVDKAAENGMDVFRVFDALNDIRNLRRSIAAVRRTGKHAQGTICYTVSPLHTPGDFVEMA
EKLLELGCDSICIKDMAALLKPQAAFDIVQGIKETCGQNTRVHVHVHATTGVTLVSLMKAIEAGADCVDTCISSLSLGPG
HNPTESLVEMLDGTGFETKLDRKRLISIKKYFAGIRPRYQEFLSNITGVETEIFASQIPGGMLSNMESQLKQQGAGDRME
EVLLEVPKVRADAGFPPLVTPSSQIVGTQAVFNVMMGRYKVMTGEFADLMLGYYGETIGPRDPAVIAQAHKQTGKNPING
RPADLLKPEWHELRDAAVALEGCNGTDEDVLTYAMFPKVAPTFFPARARGPKNLGKDPVAHPAAATAAAPVKSGPADSGK
GPVTTTITYDVKYNGKTHKVTVAACK

Specific function: The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=454, Percent_Identity=33.920704845815, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI106049295, Length=454, Percent_Identity=33.920704845815, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI106049292, Length=454, Percent_Identity=33.920704845815, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17562816, Length=462, Percent_Identity=33.982683982684, Blast_Score=238, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6319695, Length=459, Percent_Identity=33.9869281045752, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321376, Length=459, Percent_Identity=33.5511982570806, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24652212, Length=472, Percent_Identity=32.6271186440678, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24652210, Length=472, Percent_Identity=32.6271186440678, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24652214, Length=472, Percent_Identity=32.6271186440678, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI19921944, Length=472, Percent_Identity=32.6271186440678, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24652216, Length=472, Percent_Identity=32.6271186440678, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI281363050, Length=472, Percent_Identity=32.6271186440678, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24652224, Length=472, Percent_Identity=32.6271186440678, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24652222, Length=472, Percent_Identity=32.6271186440678, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24652220, Length=472, Percent_Identity=32.6271186440678, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24652218, Length=472, Percent_Identity=32.6271186440678, Blast_Score=231, Evalue=6e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003379
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 55476; Mature: 55345

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTIDVTELVLRDGHQSLMATRMAMEDMIPACADIDQAGYWSVECWGGATFDSCIRFLN
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
EDPWERLRQFRKLLPNSRLQMLLRGQNLLGYRHYEDSVVDRFVDKAAENGMDVFRVFDAL
CCHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NDIRNLRRSIAAVRRTGKHAQGTICYTVSPLHTPGDFVEMAEKLLELGCDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LKPQAAFDIVQGIKETCGQNTRVHVHVHATTGVTLVSLMKAIEAGADCVDTCISSLSLGP
HCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GHNPTESLVEMLDGTGFETKLDRKRLISIKKYFAGIRPRYQEFLSNITGVETEIFASQIP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCC
GGMLSNMESQLKQQGAGDRMEEVLLEVPKVRADAGFPPLVTPSSQIVGTQAVFNVMMGRY
CHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KVMTGEFADLMLGYYGETIGPRDPAVIAQAHKQTGKNPINGRPADLLKPEWHELRDAAVA
HEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHE
LEGCNGTDEDVLTYAMFPKVAPTFFPARARGPKNLGKDPVAHPAAATAAAPVKSGPADSG
EECCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
KGPVTTTITYDVKYNGKTHKVTVAACK
CCCEEEEEEEEEEECCCEEEEEEEECC
>Mature Secondary Structure 
PKTIDVTELVLRDGHQSLMATRMAMEDMIPACADIDQAGYWSVECWGGATFDSCIRFLN
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
EDPWERLRQFRKLLPNSRLQMLLRGQNLLGYRHYEDSVVDRFVDKAAENGMDVFRVFDAL
CCHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NDIRNLRRSIAAVRRTGKHAQGTICYTVSPLHTPGDFVEMAEKLLELGCDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LKPQAAFDIVQGIKETCGQNTRVHVHVHATTGVTLVSLMKAIEAGADCVDTCISSLSLGP
HCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GHNPTESLVEMLDGTGFETKLDRKRLISIKKYFAGIRPRYQEFLSNITGVETEIFASQIP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCC
GGMLSNMESQLKQQGAGDRMEEVLLEVPKVRADAGFPPLVTPSSQIVGTQAVFNVMMGRY
CHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KVMTGEFADLMLGYYGETIGPRDPAVIAQAHKQTGKNPINGRPADLLKPEWHELRDAAVA
HEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHE
LEGCNGTDEDVLTYAMFPKVAPTFFPARARGPKNLGKDPVAHPAAATAAAPVKSGPADSG
EECCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
KGPVTTTITYDVKYNGKTHKVTVAACK
CCCEEEEEEEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365490 [H]