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The map label for this gene is polX [H]

Identifier: 116625961

GI number: 116625961

Start: 8689821

End: 8691536

Strand: Reverse

Name: polX [H]

Synonym: Acid_6919

Alternate gene names: 116625961

Gene position: 8691536-8689821 (Counterclockwise)

Preceding gene: 116625962

Following gene: 116625960

Centisome position: 87.22

GC content: 58.28

Gene sequence:

>1716_bases
ATGGGTACCCGCGATGCTAAACTTTCCGCCGCCGCGCCATCGTCCGCGCTCAGCAACGCGCAGATTGCCGACAAGTTGGC
TGGCCTCGCACAGTTACTATCGACCAACAAAGAGAATCCGTATAAAGTCAAAGCCTACCGTCGCGCGGCGGCGAAGATCC
GGTCTATATCGGAGAGTCTGGACGAGCTTGTCCGCGAAGATGCCGATCTGACGAGTTTTTCCGGCATCGGCGACGCCATC
GCGAGCGCCATCCGGGAGATTGTCCTGACGGGGACGCTCAGGAAACTGGACACGCTGCGCGGTCAGGCCGCGCCGGAGGT
CGCGAATTTGGCGGACTATCCGCGGCTCGATCCGAAACGCGTTTTGCGCACATACAAAAAGTTGAAGATCTCATCGATTG
AAGAACTCCGGGAAAAACTGGAGAGCGGCGCGATTGCGGCGGCGCTTGGCCAGCGCATGGCGCAGCATGTTCGCCAGGGA
CTCTCCGAAGCACACGCGATACTCCTTTATCATGCCGACGATCTACAGGGCGCGATCGAAGGTTTTTTAATAGGGAAGTG
CGGTGTGGCAGCGGTACAGGTAGTGGGCGCTTGCCGCCGGCGCGTAGAGGTCGTCCACGAGATCGCTTTTGTGATCCAGA
CGGGCGACTTCCCGGCTGTGGTGAGAAAGGTGGAACGGTATGGCGGCCAGACGCCGCTATTCGAATCGTCCAGAGATCTG
GCGCGTTTCGCCCTTTCCTCCGGCATCGAGCTTCGCCTTCGTCGCGCGAAAGCCGGCAATTGGGGCCTGTGTCTGATCGC
CGAAACCGGCTCGGAAGCGCACCTACGGAAACTGGAACTGGTGACGGGAAAACTAACCGCGATTTCCGCCAAGGGTCCTT
TCCCCACGGAAGCTGCATTCTACAGCGCGTTCGAGATGTCGTATATCGAGCCGGAACTGCGTGAGGGCCATGATGAGATC
GCACGCGCCCTGCAAGGAACTCTTCCGAAGCTTGTTACCGCTGCTGATATCCGCGGCGAACTCCACGCGCATTCCACTTC
AAGCGATGGCGTGCATTCGATCGAGCAGATGGCCATCGCCGCACGGGAACGCGGTTATGAATATATCGGAATCTCCGACC
ACTCGCAGAGCCTCAAAATCGCGAAGGGAGTTTCGATCGAGGATCTGTGGGCGCAGATCAAATACATCGACAGGCTCAAT
GAAAAGCTGAAAAGCGTTCGGATCCTCAAATCCTCGGAAGTGGACATTCTCGCAGATGGGACTCTGGACTATCCGGACGA
TCTCCTGCGGGCGTTGGATTATACCGTTTGTTCAGTTCACTCGCGCTTCGGGTTGAACCGTGAGCAACAGACCGAGCGCA
TCATGCGCGCCATGGATAATCGCTATTTCAATATTCTGGGCCATGCCACGGGCCGCCTGCTGCTGAAGCGGCCCGGTTAC
GAAGTGGACATGACTCGCATCATCGCCCATGCCAAGGCTACTGATTGTCTCTTCGAGATTAATTCGAGTCCCGACCGTTT
GGATCTATCGGCCGAGCACGCCAGGATGGCGAACCAAGCCGGTGTGAAGATTGCCGTTACAACCGACGCGCACAGCACGC
GCGAATTCGGCACGGTGCAACATGGGATTGATCAGGCGCGGAGGGCCGGCCTGGAGCCGGCTTCTGTCCTCAATTGCTTG
CCGTGGGCGTCTCTTCAGCCATTGTTCCGCCGATGA

Upstream 100 bases:

>100_bases
CAAAGAGACGACGCGCGCATCGGTCATTCCATCGGCCGGGTTGCGAGTGGACGCGTTACGAGCCGCAAGCCGGCGCAATA
GCAGAACCAAGGCTTAGCGT

Downstream 100 bases:

>100_bases
TGAAGGATTATGAGCACGCACAAAGAGTTCACCGGATTCGTTACCGTCAAGGGCGCGCGGCAGCACAACCTGAAGGATAT
CGACGTCCGCATACCACGCA

Product: phosphotransferase domain-containing protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MGTRDAKLSAAAPSSALSNAQIADKLAGLAQLLSTNKENPYKVKAYRRAAAKIRSISESLDELVREDADLTSFSGIGDAI
ASAIREIVLTGTLRKLDTLRGQAAPEVANLADYPRLDPKRVLRTYKKLKISSIEELREKLESGAIAAALGQRMAQHVRQG
LSEAHAILLYHADDLQGAIEGFLIGKCGVAAVQVVGACRRRVEVVHEIAFVIQTGDFPAVVRKVERYGGQTPLFESSRDL
ARFALSSGIELRLRRAKAGNWGLCLIAETGSEAHLRKLELVTGKLTAISAKGPFPTEAAFYSAFEMSYIEPELREGHDEI
ARALQGTLPKLVTAADIRGELHAHSTSSDGVHSIEQMAIAARERGYEYIGISDHSQSLKIAKGVSIEDLWAQIKYIDRLN
EKLKSVRILKSSEVDILADGTLDYPDDLLRALDYTVCSVHSRFGLNREQQTERIMRAMDNRYFNILGHATGRLLLKRPGY
EVDMTRIIAHAKATDCLFEINSSPDRLDLSAEHARMANQAGVKIAVTTDAHSTREFGTVQHGIDQARRAGLEPASVLNCL
PWASLQPLFRR

Sequences:

>Translated_571_residues
MGTRDAKLSAAAPSSALSNAQIADKLAGLAQLLSTNKENPYKVKAYRRAAAKIRSISESLDELVREDADLTSFSGIGDAI
ASAIREIVLTGTLRKLDTLRGQAAPEVANLADYPRLDPKRVLRTYKKLKISSIEELREKLESGAIAAALGQRMAQHVRQG
LSEAHAILLYHADDLQGAIEGFLIGKCGVAAVQVVGACRRRVEVVHEIAFVIQTGDFPAVVRKVERYGGQTPLFESSRDL
ARFALSSGIELRLRRAKAGNWGLCLIAETGSEAHLRKLELVTGKLTAISAKGPFPTEAAFYSAFEMSYIEPELREGHDEI
ARALQGTLPKLVTAADIRGELHAHSTSSDGVHSIEQMAIAARERGYEYIGISDHSQSLKIAKGVSIEDLWAQIKYIDRLN
EKLKSVRILKSSEVDILADGTLDYPDDLLRALDYTVCSVHSRFGLNREQQTERIMRAMDNRYFNILGHATGRLLLKRPGY
EVDMTRIIAHAKATDCLFEINSSPDRLDLSAEHARMANQAGVKIAVTTDAHSTREFGTVQHGIDQARRAGLEPASVLNCL
PWASLQPLFRR
>Mature_570_residues
GTRDAKLSAAAPSSALSNAQIADKLAGLAQLLSTNKENPYKVKAYRRAAAKIRSISESLDELVREDADLTSFSGIGDAIA
SAIREIVLTGTLRKLDTLRGQAAPEVANLADYPRLDPKRVLRTYKKLKISSIEELREKLESGAIAAALGQRMAQHVRQGL
SEAHAILLYHADDLQGAIEGFLIGKCGVAAVQVVGACRRRVEVVHEIAFVIQTGDFPAVVRKVERYGGQTPLFESSRDLA
RFALSSGIELRLRRAKAGNWGLCLIAETGSEAHLRKLELVTGKLTAISAKGPFPTEAAFYSAFEMSYIEPELREGHDEIA
RALQGTLPKLVTAADIRGELHAHSTSSDGVHSIEQMAIAARERGYEYIGISDHSQSLKIAKGVSIEDLWAQIKYIDRLNE
KLKSVRILKSSEVDILADGTLDYPDDLLRALDYTVCSVHSRFGLNREQQTERIMRAMDNRYFNILGHATGRLLLKRPGYE
VDMTRIIAHAKATDCLFEINSSPDRLDLSAEHARMANQAGVKIAVTTDAHSTREFGTVQHGIDQARRAGLEPASVLNCLP
WASLQPLFRR

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62680; Mature: 62549

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTRDAKLSAAAPSSALSNAQIADKLAGLAQLLSTNKENPYKVKAYRRAAAKIRSISESL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
DELVREDADLTSFSGIGDAIASAIREIVLTGTLRKLDTLRGQAAPEVANLADYPRLDPKR
HHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHH
VLRTYKKLKISSIEELREKLESGAIAAALGQRMAQHVRQGLSEAHAILLYHADDLQGAIE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHH
GFLIGKCGVAAVQVVGACRRRVEVVHEIAFVIQTGDFPAVVRKVERYGGQTPLFESSRDL
HHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHH
ARFALSSGIELRLRRAKAGNWGLCLIAETGSEAHLRKLELVTGKLTAISAKGPFPTEAAF
HHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHH
YSAFEMSYIEPELREGHDEIARALQGTLPKLVTAADIRGELHAHSTSSDGVHSIEQMAIA
HHHHHHHHCCHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHH
ARERGYEYIGISDHSQSLKIAKGVSIEDLWAQIKYIDRLNEKLKSVRILKSSEVDILADG
HHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TLDYPDDLLRALDYTVCSVHSRFGLNREQQTERIMRAMDNRYFNILGHATGRLLLKRPGY
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEHHHHCCCEEEEECCCC
EVDMTRIIAHAKATDCLFEINSSPDRLDLSAEHARMANQAGVKIAVTTDAHSTREFGTVQ
CHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
HGIDQARRAGLEPASVLNCLPWASLQPLFRR
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure 
GTRDAKLSAAAPSSALSNAQIADKLAGLAQLLSTNKENPYKVKAYRRAAAKIRSISESL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
DELVREDADLTSFSGIGDAIASAIREIVLTGTLRKLDTLRGQAAPEVANLADYPRLDPKR
HHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHH
VLRTYKKLKISSIEELREKLESGAIAAALGQRMAQHVRQGLSEAHAILLYHADDLQGAIE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHH
GFLIGKCGVAAVQVVGACRRRVEVVHEIAFVIQTGDFPAVVRKVERYGGQTPLFESSRDL
HHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHH
ARFALSSGIELRLRRAKAGNWGLCLIAETGSEAHLRKLELVTGKLTAISAKGPFPTEAAF
HHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHH
YSAFEMSYIEPELREGHDEIARALQGTLPKLVTAADIRGELHAHSTSSDGVHSIEQMAIA
HHHHHHHHCCHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHH
ARERGYEYIGISDHSQSLKIAKGVSIEDLWAQIKYIDRLNEKLKSVRILKSSEVDILADG
HHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
TLDYPDDLLRALDYTVCSVHSRFGLNREQQTERIMRAMDNRYFNILGHATGRLLLKRPGY
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEHHHHCCCEEEEECCCC
EVDMTRIIAHAKATDCLFEINSSPDRLDLSAEHARMANQAGVKIAVTTDAHSTREFGTVQ
CHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
HGIDQARRAGLEPASVLNCLPWASLQPLFRR
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]