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The map label for this gene is dgoD [H]

Identifier: 116625826

GI number: 116625826

Start: 8500486

End: 8501619

Strand: Direct

Name: dgoD [H]

Synonym: Acid_6777

Alternate gene names: 116625826

Gene position: 8500486-8501619 (Clockwise)

Preceding gene: 116625825

Following gene: 116625827

Centisome position: 85.3

GC content: 63.93

Gene sequence:

>1134_bases
ATGAATATGAAACGCAGATTGACGATACCTCCCCTGGCCTTCGCGCCGCCACAAAGCGCCGGCCATCCGCTTGAGATCGT
GCAGTTCCATGCCTGGCGTCTGAAGGAGCCGGTCTCGGGCCGGCGGTACACGGTGGTCGAGCTTCAATCGCGCAGCGGCG
AGACCGGCTATGGCGAAGGCGGACCTGTCCCCGCCGCGGAGATCGTCGAAGCGCGCGCGGCTATCCAAGGACGGCGGGTA
ACGGAATCGGAGTTTGTTCGCGCGCGGCTGGCGGGCATACCCGCCATGGAGGCCGCTGTAGGTAACGCGATGCTGGACCT
GTTCTCGAAATCCAGGAAGGTCCCCATTTACCAGTTCCTTGGCGGCCCCACGCGCTTCAAGGCGCGTCTGCTGGCCCGGT
TGGAGGGGAGCGACGAGGCGTCGGCGGCGGCGCCACTCGAGCGCGCCAAACGGCAGGGTTTCCGTGCCTTCACCCTCCCG
GCGCTCCAGCGCGATGCGATGATCCCATTGCAGGAATATGTCGATCGCGTCAGGGCCCAGGTGGCGAAAATGCAGAGTAT
GGGCGGATCCACAGCCGAATGGGTGCTCGACGGCGCGGCCGCCATGACGCCGGGTGATGCAGCCACGGTCGCCAAAGCTC
TCGAGAGAGTCCATATGATTTGGTTCGATGAGCCGACCAATGTGCTTACCACCGATGGCCTGGCCAAGATCACCGACGAG
AGCGTGATGCCCATCGGACTCGGCCGCAAGATTCACGACATTCCCGCATTTCAAAACCTGTTGCGCCAAGCCTCGGTGAA
TGTGCTGCGGCCTGGCCTCGGATTGAATAGCCTGACCAAGATCAAGCGGATCGCGGCGCTCGCGGAAACACACTACGTGG
CCGTCGCCCCGTACCACGAGGGCGGGCCGATTGGCGCCATGGCCGGCGTACAACTGGCAGCCGCCCTCGCGAACTCCTAC
GCCGTGGATGTGCCGGTGCCTACCGCCGACCGCGATGCAGCCATGCGCGCCGAACTCACCTCCGGCAACAAAGAAGCGGC
CGAAAACGGTTTCGCCGCCCTGATGAATCGTCCGGGCCTGGGATTCGAGGTGAACCGCAAGGCTCTCGACACGTACAGTG
AGGAGCGTATATGA

Upstream 100 bases:

>100_bases
TGCTCCAACTCTATGACAAGCACAATACACGAACCGAGGTCATGGTTCGCAAGCCGGTTCAGAAACCTTGCTGTTCGGAG
AATCTGGATCCCTACATAAA

Downstream 100 bases:

>100_bases
AGCGCCGAAACCTTTTAGGAATGTTCGCCGCCGCAGGCGCGATGGGCGCGAACCGCCGGCGGCTGGTGGACTGCGGCTGT
GCCATGCAAGTGCAGCACTC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNMKRRLTIPPLAFAPPQSAGHPLEIVQFHAWRLKEPVSGRRYTVVELQSRSGETGYGEGGPVPAAEIVEARAAIQGRRV
TESEFVRARLAGIPAMEAAVGNAMLDLFSKSRKVPIYQFLGGPTRFKARLLARLEGSDEASAAAPLERAKRQGFRAFTLP
ALQRDAMIPLQEYVDRVRAQVAKMQSMGGSTAEWVLDGAAAMTPGDAATVAKALERVHMIWFDEPTNVLTTDGLAKITDE
SVMPIGLGRKIHDIPAFQNLLRQASVNVLRPGLGLNSLTKIKRIAALAETHYVAVAPYHEGGPIGAMAGVQLAAALANSY
AVDVPVPTADRDAAMRAELTSGNKEAAENGFAALMNRPGLGFEVNRKALDTYSEERI

Sequences:

>Translated_377_residues
MNMKRRLTIPPLAFAPPQSAGHPLEIVQFHAWRLKEPVSGRRYTVVELQSRSGETGYGEGGPVPAAEIVEARAAIQGRRV
TESEFVRARLAGIPAMEAAVGNAMLDLFSKSRKVPIYQFLGGPTRFKARLLARLEGSDEASAAAPLERAKRQGFRAFTLP
ALQRDAMIPLQEYVDRVRAQVAKMQSMGGSTAEWVLDGAAAMTPGDAATVAKALERVHMIWFDEPTNVLTTDGLAKITDE
SVMPIGLGRKIHDIPAFQNLLRQASVNVLRPGLGLNSLTKIKRIAALAETHYVAVAPYHEGGPIGAMAGVQLAAALANSY
AVDVPVPTADRDAAMRAELTSGNKEAAENGFAALMNRPGLGFEVNRKALDTYSEERI
>Mature_377_residues
MNMKRRLTIPPLAFAPPQSAGHPLEIVQFHAWRLKEPVSGRRYTVVELQSRSGETGYGEGGPVPAAEIVEARAAIQGRRV
TESEFVRARLAGIPAMEAAVGNAMLDLFSKSRKVPIYQFLGGPTRFKARLLARLEGSDEASAAAPLERAKRQGFRAFTLP
ALQRDAMIPLQEYVDRVRAQVAKMQSMGGSTAEWVLDGAAAMTPGDAATVAKALERVHMIWFDEPTNVLTTDGLAKITDE
SVMPIGLGRKIHDIPAFQNLLRQASVNVLRPGLGLNSLTKIKRIAALAETHYVAVAPYHEGGPIGAMAGVQLAAALANSY
AVDVPVPTADRDAAMRAELTSGNKEAAENGFAALMNRPGLGFEVNRKALDTYSEERI

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=350, Percent_Identity=22.5714285714286, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 40630; Mature: 40630

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMKRRLTIPPLAFAPPQSAGHPLEIVQFHAWRLKEPVSGRRYTVVELQSRSGETGYGEG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCC
GPVPAAEIVEARAAIQGRRVTESEFVRARLAGIPAMEAAVGNAMLDLFSKSRKVPIYQFL
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHC
GGPTRFKARLLARLEGSDEASAAAPLERAKRQGFRAFTLPALQRDAMIPLQEYVDRVRAQ
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCCCCCHHHHHHHHHHH
VAKMQSMGGSTAEWVLDGAAAMTPGDAATVAKALERVHMIWFDEPTNVLTTDGLAKITDE
HHHHHHCCCCHHHHHCCCCHHCCCCHHHHHHHHHHHHEEEEECCCCCEEECCCCHHHCCC
SVMPIGLGRKIHDIPAFQNLLRQASVNVLRPGLGLNSLTKIKRIAALAETHYVAVAPYHE
CCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCC
GGPIGAMAGVQLAAALANSYAVDVPVPTADRDAAMRAELTSGNKEAAENGFAALMNRPGL
CCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
GFEVNRKALDTYSEERI
CEEECHHHHHHHHHCCC
>Mature Secondary Structure
MNMKRRLTIPPLAFAPPQSAGHPLEIVQFHAWRLKEPVSGRRYTVVELQSRSGETGYGEG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCC
GPVPAAEIVEARAAIQGRRVTESEFVRARLAGIPAMEAAVGNAMLDLFSKSRKVPIYQFL
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHC
GGPTRFKARLLARLEGSDEASAAAPLERAKRQGFRAFTLPALQRDAMIPLQEYVDRVRAQ
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCCCCCHHHHHHHHHHH
VAKMQSMGGSTAEWVLDGAAAMTPGDAATVAKALERVHMIWFDEPTNVLTTDGLAKITDE
HHHHHHCCCCHHHHHCCCCHHCCCCHHHHHHHHHHHHEEEEECCCCCEEECCCCHHHCCC
SVMPIGLGRKIHDIPAFQNLLRQASVNVLRPGLGLNSLTKIKRIAALAETHYVAVAPYHE
CCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCC
GGPIGAMAGVQLAAALANSYAVDVPVPTADRDAAMRAELTSGNKEAAENGFAALMNRPGL
CCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
GFEVNRKALDTYSEERI
CEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA