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The map label for this gene is atoS [C]

Identifier: 116625799

GI number: 116625799

Start: 8454552

End: 8456807

Strand: Direct

Name: atoS [C]

Synonym: Acid_6749

Alternate gene names: 116625799

Gene position: 8454552-8456807 (Clockwise)

Preceding gene: 116625798

Following gene: 116625802

Centisome position: 84.84

GC content: 59.53

Gene sequence:

>2256_bases
GTGAGCATTAACGAAGAGATGTATCGGCGGATCGTCGAGGCCGTTCCGGAGGGCATATGGGTCGTCGGCGGTGAGGGCCG
GACAATCTTCAGCAACCGGCGCATGGCTGAGATTCTGGGAGTCGAGTACGAGTCGATGTCCGAACAAACCTGTTTTGGCT
GCGTTTTTCCGGACGAACTCGCGGATGCGGAGCGCCATTTTGCGCGCACATTTGGCGGCGACTCCCGGCCCTTCGATTTT
CGCCTGCGCCGCGGCGACGGATCACCGGTCTGGGTGAGTATTTCCTGCATGCCGGTTCACGACGATAAGGGGACTCAGGT
CGGGCTGTTAGGCCTCTTCTCGGATATCACCGAGCGCAAGCAGGCGGAGGCCGCACTGAGGGAGAGCGAAGAGCGATTCC
GGAACATGGCGGACACGGCGCCGGTGATGATCTGGGTCTCCGACGAGAACAAGCAACTGACCTTCTTCAACAAGACTTGG
TTGAAGTTCACGGGCCGCACCATGGAGCAGGAACTGGGGGAGGGTTGGGCCGCCGGAGTACATCCCGAGGATATCCAGAA
CTGCTATGAGACCTTCTGCTCCGCATTCGACGCGCACAGGAACTTTCAGATAGAGCTCCGGCTGCGACGAGCGGACGGCG
AGTACCGGTCGATGCTGTGCAGCGGTGTCCCGCGTTTTGCTCCGGGCGGCGTTTTCGCCGGCTATATCGGCTGCGACATC
GACATCACCGATCTGCAGAGCGAAGAACGGTTTCGGGAGCTGGCGGAAAACATTAACCAGGTTTTCTGGATGCTCGACCT
CGACACATCCCGTGTGCTTTACATCAGCCCCTCCTTCGAAAAGGTATGGGGTTGCAGCGCCGCGGCTTATCAGGATCACG
ATTGGCTGGTGGAAACGGTGCACGCGGAGGATCGAGGGCGCTTCATTTTATTCCGCGAAAGCGCTAAGGCGGAGGCGGTT
GAAGAAACCTACCGCATCGTGCGCCCGGACGGTACGATCCGATGGATCCATGACCGGGCCTTTCTGGTTCGCGATTCGGA
GGGCAAGCCATACCGTGTGGCGGGAATCGCGGAGGACGTTACGGCGCACCGGGAGTTGGAAGAGGAACTCCGCCAGGCGC
ACAAGATGGAGGCGATCGGGAGGCTGGCAGGAGGTGTCGCACATGACTTCAACAACCTGCTGACAGTGATCGGCGGTTAT
GCGAGGATGCTTTTCGATGGCGCGAACGCCCAGGACCCGACGCGAGCCAAGCTGGAGCAAATCCTGACTGCATCCGACCG
TGCCAGCGTGCTTACGATGCAGCTGCTGGCAATCAGCCGCCGCCACGCGATCCAACCCAAGCTGGTCAACGTGAACAATC
TGCTGACCAGTATGGCGAGCCTGCTGCGCCGGATCATCGGGGAGCATATCACGATCGAGACCGCGCTCGATCCCGAACTG
AGCTGCATCAAGGTGGATCCGCATCAAATCGAGCAGGTGGTGATGAACCTGGCGGCGAACGCACGCGACGCGATGCCGAA
CGCAGGGAAGTTCCGGATTGAAACCAGTATGGCGCTCGCGCCCGACAAGCCGGGCGAGGACAGCGGGCGGAGTGCGGCGA
AATGTGTCCGGCTAAGGATTGGCGATACCGGATGCGGCATGGACGACCGTACGCGGCAGCGGGCATTTGAGCCATTCTTT
ACGACAAAGGGAGTAGGGAGAGGAACCGGTTTGGGGCTGAGCATGGTTTACGGCTTCGTGCACCAAAACCAAGGCACGAT
TCATGTCTCGAGCGAGCCCGGCCAAGGCACGATTTTCGATCTCTGTTTTCCGGCGCAACCAGAGCGTGAAGCCGAGCCCG
AGACTCCGGTCAACCGGCTGAGTAAGACGGATGCCACTGAAACGGTGCTGGTGGCCGAGGATGAACCGGCGGTTCGCGAG
CTGGTCAGGCAGACACTGGAACAGCGCGGATATACGGTGCTGGAGGCTAAGGACGGATATGAGGCCTTGCGCGTTTTTGA
ACAGCGCAAGAACGAAATCCATTTGCTGCTCACGGATGTGATCATGCCGTTAATGAACGGCCGCGAACTTGCCAAACGGC
TGGAATCACTTCGCCCCGGGATGAAAATCGTTTACATGTCGGGCTACACGGATGAGGTGCTGGCCTTTCACGGATTTGCT
CAACCGGAGATCGAGTTTATTCAGAAGCCGTTCACTGCGTCCGAGCTGGCGAATAAGGTAGAACTGGTGCTGTCCGTGGA
CAGGCGGGCAACGTAG

Upstream 100 bases:

>100_bases
CGGTTGCGGCTCGTTTTCATCCGCGGATCCTGATTGTCTCCGACGCAGGGGAGTCCTGGTATCCTGTTTGGTTCCCGGAT
CTAAATGTGAGCACCAACCT

Downstream 100 bases:

>100_bases
GCGACACCGTGTCCCGTCTAGGTAGAGGACGCCTGAGTCGCATAGGCTGCGGCAATGCGTTCGGCATCGTCGAAGAACAA
TCCTTCCCCTACAGGCATGA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 751; Mature: 750

Protein sequence:

>751_residues
MSINEEMYRRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGVEYESMSEQTCFGCVFPDELADAERHFARTFGGDSRPFDF
RLRRGDGSPVWVSISCMPVHDDKGTQVGLLGLFSDITERKQAEAALRESEERFRNMADTAPVMIWVSDENKQLTFFNKTW
LKFTGRTMEQELGEGWAAGVHPEDIQNCYETFCSAFDAHRNFQIELRLRRADGEYRSMLCSGVPRFAPGGVFAGYIGCDI
DITDLQSEERFRELAENINQVFWMLDLDTSRVLYISPSFEKVWGCSAAAYQDHDWLVETVHAEDRGRFILFRESAKAEAV
EETYRIVRPDGTIRWIHDRAFLVRDSEGKPYRVAGIAEDVTAHRELEEELRQAHKMEAIGRLAGGVAHDFNNLLTVIGGY
ARMLFDGANAQDPTRAKLEQILTASDRASVLTMQLLAISRRHAIQPKLVNVNNLLTSMASLLRRIIGEHITIETALDPEL
SCIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETSMALAPDKPGEDSGRSAAKCVRLRIGDTGCGMDDRTRQRAFEPFF
TTKGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFDLCFPAQPEREAEPETPVNRLSKTDATETVLVAEDEPAVRE
LVRQTLEQRGYTVLEAKDGYEALRVFEQRKNEIHLLLTDVIMPLMNGRELAKRLESLRPGMKIVYMSGYTDEVLAFHGFA
QPEIEFIQKPFTASELANKVELVLSVDRRAT

Sequences:

>Translated_751_residues
MSINEEMYRRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGVEYESMSEQTCFGCVFPDELADAERHFARTFGGDSRPFDF
RLRRGDGSPVWVSISCMPVHDDKGTQVGLLGLFSDITERKQAEAALRESEERFRNMADTAPVMIWVSDENKQLTFFNKTW
LKFTGRTMEQELGEGWAAGVHPEDIQNCYETFCSAFDAHRNFQIELRLRRADGEYRSMLCSGVPRFAPGGVFAGYIGCDI
DITDLQSEERFRELAENINQVFWMLDLDTSRVLYISPSFEKVWGCSAAAYQDHDWLVETVHAEDRGRFILFRESAKAEAV
EETYRIVRPDGTIRWIHDRAFLVRDSEGKPYRVAGIAEDVTAHRELEEELRQAHKMEAIGRLAGGVAHDFNNLLTVIGGY
ARMLFDGANAQDPTRAKLEQILTASDRASVLTMQLLAISRRHAIQPKLVNVNNLLTSMASLLRRIIGEHITIETALDPEL
SCIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETSMALAPDKPGEDSGRSAAKCVRLRIGDTGCGMDDRTRQRAFEPFF
TTKGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFDLCFPAQPEREAEPETPVNRLSKTDATETVLVAEDEPAVRE
LVRQTLEQRGYTVLEAKDGYEALRVFEQRKNEIHLLLTDVIMPLMNGRELAKRLESLRPGMKIVYMSGYTDEVLAFHGFA
QPEIEFIQKPFTASELANKVELVLSVDRRAT
>Mature_750_residues
SINEEMYRRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGVEYESMSEQTCFGCVFPDELADAERHFARTFGGDSRPFDFR
LRRGDGSPVWVSISCMPVHDDKGTQVGLLGLFSDITERKQAEAALRESEERFRNMADTAPVMIWVSDENKQLTFFNKTWL
KFTGRTMEQELGEGWAAGVHPEDIQNCYETFCSAFDAHRNFQIELRLRRADGEYRSMLCSGVPRFAPGGVFAGYIGCDID
ITDLQSEERFRELAENINQVFWMLDLDTSRVLYISPSFEKVWGCSAAAYQDHDWLVETVHAEDRGRFILFRESAKAEAVE
ETYRIVRPDGTIRWIHDRAFLVRDSEGKPYRVAGIAEDVTAHRELEEELRQAHKMEAIGRLAGGVAHDFNNLLTVIGGYA
RMLFDGANAQDPTRAKLEQILTASDRASVLTMQLLAISRRHAIQPKLVNVNNLLTSMASLLRRIIGEHITIETALDPELS
CIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETSMALAPDKPGEDSGRSAAKCVRLRIGDTGCGMDDRTRQRAFEPFFT
TKGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFDLCFPAQPEREAEPETPVNRLSKTDATETVLVAEDEPAVREL
VRQTLEQRGYTVLEAKDGYEALRVFEQRKNEIHLLLTDVIMPLMNGRELAKRLESLRPGMKIVYMSGYTDEVLAFHGFAQ
PEIEFIQKPFTASELANKVELVLSVDRRAT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=268, Percent_Identity=32.4626865671642, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=29.2682926829268, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=367, Percent_Identity=26.158038147139, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI87081816, Length=375, Percent_Identity=27.2, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=28.4, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=430, Percent_Identity=23.0232558139535, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84543; Mature: 84412

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINEEMYRRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGVEYESMSEQTCFGCVFPDEL
CCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCCHHHHHCCCHHCCCCCCEEEECCCHHH
ADAERHFARTFGGDSRPFDFRLRRGDGSPVWVSISCMPVHDDKGTQVGLLGLFSDITERK
HHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEEEHHHHHHHHHHHH
QAEAALRESEERFRNMADTAPVMIWVSDENKQLTFFNKTWLKFTGRTMEQELGEGWAAGV
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEHHCCCCHHHHHHCCCCCCCC
HPEDIQNCYETFCSAFDAHRNFQIELRLRRADGEYRSMLCSGVPRFAPGGVFAGYIGCDI
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEEEECCE
DITDLQSEERFRELAENINQVFWMLDLDTSRVLYISPSFEKVWGCSAAAYQDHDWLVETV
EECCCCCHHHHHHHHHHHHHEEEEEEECCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEE
HAEDRGRFILFRESAKAEAVEETYRIVRPDGTIRWIHDRAFLVRDSEGKPYRVAGIAEDV
EECCCCCEEEEECCCHHHHHHHHHHEECCCCCEEEEECEEEEEECCCCCCEEEECCHHHH
TAHRELEEELRQAHKMEAIGRLAGGVAHDFNNLLTVIGGYARMLFDGANAQDPTRAKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILTASDRASVLTMQLLAISRRHAIQPKLVNVNNLLTSMASLLRRIIGEHITIETALDPEL
HHCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
SCIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETSMALAPDKPGEDSGRSAAKCVRLRI
EEEECCHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHEEEEEE
GDTGCGMDDRTRQRAFEPFFTTKGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFD
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEE
LCFPAQPEREAEPETPVNRLSKTDATETVLVAEDEPAVRELVRQTLEQRGYTVLEAKDGY
EECCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCH
EALRVFEQRKNEIHLLLTDVIMPLMNGRELAKRLESLRPGMKIVYMSGYTDEVLAFHGFA
HHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCC
QPEIEFIQKPFTASELANKVELVLSVDRRAT
CCHHHHHHCCCCHHHHHHHEEEEEECCCCCC
>Mature Secondary Structure 
SINEEMYRRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGVEYESMSEQTCFGCVFPDEL
CCCHHHHHHHHHHCCCCEEEECCCCCEEECCCCHHHHHCCCHHCCCCCCEEEECCCHHH
ADAERHFARTFGGDSRPFDFRLRRGDGSPVWVSISCMPVHDDKGTQVGLLGLFSDITERK
HHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEEEHHHHHHHHHHHH
QAEAALRESEERFRNMADTAPVMIWVSDENKQLTFFNKTWLKFTGRTMEQELGEGWAAGV
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEHHCCCCHHHHHHCCCCCCCC
HPEDIQNCYETFCSAFDAHRNFQIELRLRRADGEYRSMLCSGVPRFAPGGVFAGYIGCDI
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEEEECCE
DITDLQSEERFRELAENINQVFWMLDLDTSRVLYISPSFEKVWGCSAAAYQDHDWLVETV
EECCCCCHHHHHHHHHHHHHEEEEEEECCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEE
HAEDRGRFILFRESAKAEAVEETYRIVRPDGTIRWIHDRAFLVRDSEGKPYRVAGIAEDV
EECCCCCEEEEECCCHHHHHHHHHHEECCCCCEEEEECEEEEEECCCCCCEEEECCHHHH
TAHRELEEELRQAHKMEAIGRLAGGVAHDFNNLLTVIGGYARMLFDGANAQDPTRAKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILTASDRASVLTMQLLAISRRHAIQPKLVNVNNLLTSMASLLRRIIGEHITIETALDPEL
HHCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
SCIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETSMALAPDKPGEDSGRSAAKCVRLRI
EEEECCHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHEEEEEE
GDTGCGMDDRTRQRAFEPFFTTKGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFD
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEE
LCFPAQPEREAEPETPVNRLSKTDATETVLVAEDEPAVRELVRQTLEQRGYTVLEAKDGY
EECCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCH
EALRVFEQRKNEIHLLLTDVIMPLMNGRELAKRLESLRPGMKIVYMSGYTDEVLAFHGFA
HHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCC
QPEIEFIQKPFTASELANKVELVLSVDRRAT
CCHHHHHHCCCCHHHHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA