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The map label for this gene is atoS [H]

Identifier: 116625742

GI number: 116625742

Start: 8395471

End: 8397234

Strand: Reverse

Name: atoS [H]

Synonym: Acid_6692

Alternate gene names: 116625742

Gene position: 8397234-8395471 (Counterclockwise)

Preceding gene: 116625743

Following gene: 116625741

Centisome position: 84.26

GC content: 63.04

Gene sequence:

>1764_bases
ATGAGATCACGTTTCTCCCGGCTGTCGCTGCTCACCAAGATCATGCTCTCCACATCGGTGGCGATCACGTTGCTGTTTGC
GATCACGGGAGAGATCGTACTGCGGAATATCACCAAGACTATGTTCGACAGCCTGGAAGCCGAGGTGCATGAAAGCTTCC
ACGCGTACGATTCGCTCTGGCAATCGCGGACGCAGCTGCTCAATAGCGTGAGCCTTGTAGTGGCCAGTATGTCGGACGTG
CGCGGCGCCTTCAGCACCGGCGACCAGGCGACGATTCGCGACAGCGCGGGCGAGTTGTGGTCGCGCATCTCCGATTCCGC
CGGACTATTCCTGGTTACCGACCCGCGCGGAAAGGTCATCGCATCCCTGGGCGGAGTCACCGTACCCTCGCTTCGCAAGA
ACCTCGACCTTGTGGTCCAGGCAGAGGCGGGCTTCCCCAAGCAGGCATCGGGATTCTTCCTGCAGGAAGGCGAGCTCTAC
CACCTTTCGGTCACGCCGGTGTACGTGCAGTCCGGACGCGGCCAGGATCTTCTTAACGTGCTGGTGGCCGGCGAGAAGGT
GGATGCGCTGACCGCGCAGCGGCTGAAGGACGCCACCAACAGCGAATTCCTGTTCATCACGCCGGGAAGCGTGATCGCCT
CCACGTTGAACCCCCGTGCCACCAGCGCGGTGGTGGCGGACCTTGTGAAGAAAGGTGTCTCGCAGACCGTCAGCGATGGA
GTGGTCGAATACGCGCAGTTCGAAACTCCGCTGCTCGATATTGTCGGAAATTCTGTCGGTAAGATTTGTATTCTGCGCTC
CTTTGAAGGTCCGCAGCGTCGCATTGCGAGCGTTACCAACAACATCATCATGCTGTGGATGGGCGCCATCCTGGCAGGCT
TTGCGCTCACCTATGTACTGGCGCGGCGCATCGTGGAACCGGTGGAGCAGTTGGATCGCGCCGCCGCTGAGGTGGCGCGC
CAGAACTACGAAATCGAAGTGCCGGTGGAGAGCGAGGATGAAATGGGCCGCCTTGCGCGCACCTTCAACACTATGTGCGC
CAGCATCCGGCAGGCACGCGAAGACCTGATCCGGCAGGAACGTATCTCCACCATCGGACGGCTCTCCGGGTCGATCGTGC
ACGATCTGCGCAATCCGCTGGCGGCGATCTATGGCGGCGCGGAGATGCTGGTGGATACGGAGCTGCCGCCGCTTCACGTG
AAGCGCCTGGCGGGCAATATCTATCGGGCGTCGCGTAAGATCCAGGAACTGCTGCAGGACCTGCTCAATGTGTCGAGGGG
CAAGCAGAGCGCTCCCGAAAACTGCCGCTTGCGCGAAGTGGCTTCGGCCGCTTGCGATTCGCTCGCCACCGCCGCCGAAC
AGCAGGGTATTGCGATCTCGCTGGAGATTCCTTCGGAGATCGAAGTGCCGCTGGAGCGCAGTCGCGTGGAGCGCGTCTTC
GCCAACCTGGTCGGCAATGCGCTGGAGGCGATGCAGAGCGGCGGCGAGGTCCACATCACCGCCGAGATGCGCGACGGCGC
GGCGGTGATCCACGTGGAGGACACCGGCCCTGGCATTGCGCCCGAGATCCGTACCAAACTTTTCCAGCCCTTCGTGAGCG
CCGGCAAGCGCAACGGCCTCGGGCTCGGCCTCGCGCTCTCCCGGCAGACCGTGATCGATCACGGCGGCGACATGTGGGTG
GAATCGCACCCCGGCCGCGGCGCCCGGTTCAGCTTCCGCCTGCCCGGCGCCCATGTGGCCCAGGCGCAAAGCTTGCAGGT
GTGA

Upstream 100 bases:

>100_bases
TTTCGGAGACAGGCTTCATTCCCACGCCGCACCTCAATAAGTACGGACAGGAATATCCTCCCGCCGCCAACGACTCTACC
TATCCGGGAGCACCCAAGAA

Downstream 100 bases:

>100_bases
GGGCTACACATCATCTCTCGCATTGAGAAAACGCTTCAGAGCCGCGACCGTCAGGGAGCGGTCGGTAATTCGATTACCAA
CCGCTCCCTGACGGTCACGG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MRSRFSRLSLLTKIMLSTSVAITLLFAITGEIVLRNITKTMFDSLEAEVHESFHAYDSLWQSRTQLLNSVSLVVASMSDV
RGAFSTGDQATIRDSAGELWSRISDSAGLFLVTDPRGKVIASLGGVTVPSLRKNLDLVVQAEAGFPKQASGFFLQEGELY
HLSVTPVYVQSGRGQDLLNVLVAGEKVDALTAQRLKDATNSEFLFITPGSVIASTLNPRATSAVVADLVKKGVSQTVSDG
VVEYAQFETPLLDIVGNSVGKICILRSFEGPQRRIASVTNNIIMLWMGAILAGFALTYVLARRIVEPVEQLDRAAAEVAR
QNYEIEVPVESEDEMGRLARTFNTMCASIRQAREDLIRQERISTIGRLSGSIVHDLRNPLAAIYGGAEMLVDTELPPLHV
KRLAGNIYRASRKIQELLQDLLNVSRGKQSAPENCRLREVASAACDSLATAAEQQGIAISLEIPSEIEVPLERSRVERVF
ANLVGNALEAMQSGGEVHITAEMRDGAAVIHVEDTGPGIAPEIRTKLFQPFVSAGKRNGLGLGLALSRQTVIDHGGDMWV
ESHPGRGARFSFRLPGAHVAQAQSLQV

Sequences:

>Translated_587_residues
MRSRFSRLSLLTKIMLSTSVAITLLFAITGEIVLRNITKTMFDSLEAEVHESFHAYDSLWQSRTQLLNSVSLVVASMSDV
RGAFSTGDQATIRDSAGELWSRISDSAGLFLVTDPRGKVIASLGGVTVPSLRKNLDLVVQAEAGFPKQASGFFLQEGELY
HLSVTPVYVQSGRGQDLLNVLVAGEKVDALTAQRLKDATNSEFLFITPGSVIASTLNPRATSAVVADLVKKGVSQTVSDG
VVEYAQFETPLLDIVGNSVGKICILRSFEGPQRRIASVTNNIIMLWMGAILAGFALTYVLARRIVEPVEQLDRAAAEVAR
QNYEIEVPVESEDEMGRLARTFNTMCASIRQAREDLIRQERISTIGRLSGSIVHDLRNPLAAIYGGAEMLVDTELPPLHV
KRLAGNIYRASRKIQELLQDLLNVSRGKQSAPENCRLREVASAACDSLATAAEQQGIAISLEIPSEIEVPLERSRVERVF
ANLVGNALEAMQSGGEVHITAEMRDGAAVIHVEDTGPGIAPEIRTKLFQPFVSAGKRNGLGLGLALSRQTVIDHGGDMWV
ESHPGRGARFSFRLPGAHVAQAQSLQV
>Mature_587_residues
MRSRFSRLSLLTKIMLSTSVAITLLFAITGEIVLRNITKTMFDSLEAEVHESFHAYDSLWQSRTQLLNSVSLVVASMSDV
RGAFSTGDQATIRDSAGELWSRISDSAGLFLVTDPRGKVIASLGGVTVPSLRKNLDLVVQAEAGFPKQASGFFLQEGELY
HLSVTPVYVQSGRGQDLLNVLVAGEKVDALTAQRLKDATNSEFLFITPGSVIASTLNPRATSAVVADLVKKGVSQTVSDG
VVEYAQFETPLLDIVGNSVGKICILRSFEGPQRRIASVTNNIIMLWMGAILAGFALTYVLARRIVEPVEQLDRAAAEVAR
QNYEIEVPVESEDEMGRLARTFNTMCASIRQAREDLIRQERISTIGRLSGSIVHDLRNPLAAIYGGAEMLVDTELPPLHV
KRLAGNIYRASRKIQELLQDLLNVSRGKQSAPENCRLREVASAACDSLATAAEQQGIAISLEIPSEIEVPLERSRVERVF
ANLVGNALEAMQSGGEVHITAEMRDGAAVIHVEDTGPGIAPEIRTKLFQPFVSAGKRNGLGLGLALSRQTVIDHGGDMWV
ESHPGRGARFSFRLPGAHVAQAQSLQV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=30.9322033898305, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788393, Length=289, Percent_Identity=29.0657439446367, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=25.8928571428571, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=30.1724137931034, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789808, Length=258, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=29.1479820627803, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=284, Percent_Identity=28.169014084507, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=305, Percent_Identity=28.1967213114754, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790300, Length=226, Percent_Identity=29.2035398230088, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=265, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788713, Length=220, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=28.7610619469027, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=335, Percent_Identity=24.7761194029851, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=26.8181818181818, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787894, Length=298, Percent_Identity=25.503355704698, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=216, Percent_Identity=25.462962962963, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790567, Length=98, Percent_Identity=41.8367346938776, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=340, Percent_Identity=22.9411764705882, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63637; Mature: 63637

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRFSRLSLLTKIMLSTSVAITLLFAITGEIVLRNITKTMFDSLEAEVHESFHAYDSLW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRTQLLNSVSLVVASMSDVRGAFSTGDQATIRDSAGELWSRISDSAGLFLVTDPRGKVI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCH
ASLGGVTVPSLRKNLDLVVQAEAGFPKQASGFFLQEGELYHLSVTPVYVQSGRGQDLLNV
HHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCEEECCCEEEEEEEEEEEECCCCHHHHHH
LVAGEKVDALTAQRLKDATNSEFLFITPGSVIASTLNPRATSAVVADLVKKGVSQTVSDG
HHCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VVEYAQFETPLLDIVGNSVGKICILRSFEGPQRRIASVTNNIIMLWMGAILAGFALTYVL
HHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRIVEPVEQLDRAAAEVARQNYEIEVPVESEDEMGRLARTFNTMCASIRQAREDLIRQE
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISTIGRLSGSIVHDLRNPLAAIYGGAEMLVDTELPPLHVKRLAGNIYRASRKIQELLQD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLNVSRGKQSAPENCRLREVASAACDSLATAAEQQGIAISLEIPSEIEVPLERSRVERVF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHH
ANLVGNALEAMQSGGEVHITAEMRDGAAVIHVEDTGPGIAPEIRTKLFQPFVSAGKRNGL
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
GLGLALSRQTVIDHGGDMWVESHPGRGARFSFRLPGAHVAQAQSLQV
EEEEEECHHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHCHHCCCC
>Mature Secondary Structure
MRSRFSRLSLLTKIMLSTSVAITLLFAITGEIVLRNITKTMFDSLEAEVHESFHAYDSLW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRTQLLNSVSLVVASMSDVRGAFSTGDQATIRDSAGELWSRISDSAGLFLVTDPRGKVI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCH
ASLGGVTVPSLRKNLDLVVQAEAGFPKQASGFFLQEGELYHLSVTPVYVQSGRGQDLLNV
HHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCEEECCCEEEEEEEEEEEECCCCHHHHHH
LVAGEKVDALTAQRLKDATNSEFLFITPGSVIASTLNPRATSAVVADLVKKGVSQTVSDG
HHCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VVEYAQFETPLLDIVGNSVGKICILRSFEGPQRRIASVTNNIIMLWMGAILAGFALTYVL
HHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRIVEPVEQLDRAAAEVARQNYEIEVPVESEDEMGRLARTFNTMCASIRQAREDLIRQE
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISTIGRLSGSIVHDLRNPLAAIYGGAEMLVDTELPPLHVKRLAGNIYRASRKIQELLQD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLNVSRGKQSAPENCRLREVASAACDSLATAAEQQGIAISLEIPSEIEVPLERSRVERVF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHH
ANLVGNALEAMQSGGEVHITAEMRDGAAVIHVEDTGPGIAPEIRTKLFQPFVSAGKRNGL
HHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
GLGLALSRQTVIDHGGDMWVESHPGRGARFSFRLPGAHVAQAQSLQV
EEEEEECHHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]