Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 116625642

GI number: 116625642

Start: 8267180

End: 8268964

Strand: Reverse

Name: sglT [H]

Synonym: Acid_6591

Alternate gene names: 116625642

Gene position: 8268964-8267180 (Counterclockwise)

Preceding gene: 116625643

Following gene: 116625641

Centisome position: 82.97

GC content: 60.78

Gene sequence:

>1785_bases
ATGCAGCTTCATTCGCTCGATTGGATCATCGCGTTCCTATCCGTTGCGGTCTGCTTCGTCCCCGCGCTGTTCTTCGGAAA
GCGCTCCGGCAAGAGCACGGCGGAGTTCTTCGCCTCGGGCCGCTCCGTGCCATGGTGGCTCGCCGGCATCTCCATGGTGG
CCACCACCTTCTCCAGCGACACGCCGAACCTGGTCGCCAATTTCGTGCGCACGCAAGGCGTGGCCGGCAACTGGCAGTGG
TGGGCCTTCACCCTCACCGGCGTCTCCACGGTCTTCTTCTTCGCCCGCCTCTGGCGCCGCTCCGGCGTCCTCACCGACCT
TGAATTCTACGAGCTGCGCTACTCCGGCAAGGCCGCCAGCGCGGTCCGCGGCTTCCGGGCAGTCTATCTCGGACTCTTCT
TCAACTGCATCATCATGGCGACCGTCAACCTCGCCGCCTGCAAAATCGCCGCCATCCTTTTCGGCCTGCCGCGATGGGAA
ACGCTGCTCGCCGTGGGACTGCTCAATGTCATCTTCGCCACGCACTCCGGACTCTGGGGCGTGCTGGTGATCGACATGAT
CCAGTTCTTCATCAAGATGTCGGCCGTCATCGCCGCGGCCTATTTCGCAGTCACACTGCCCCAGGTCGGCGGCCTCTCGG
GAATGGTCGATAAGCTCTCCCACGTGCGCGGGCCGGGCGGCCTCAACTACCTCAGCCTCCTGCCCGATTTCACGAACAAC
TGGGATCTCGCGGTCGCCATCTTCATCATCCCTATCGCGATTCAATGGTGGAGCGTCTGGTATCCCGGCGCCGAACCCGG
CGGCGGCAGCTACATCGCGCAGCGCATGCTCGCCTCCAAGTCCGAGAAGGACGCGCTCGGCGGCACGCTCTTCTTCAACG
TCGCCCACTATGTTCTGCGCCCCTGGCCGTGGATCCTAGTCGGCCTCTGCTCCATCATTGTTTATCCCCAACTCTCCGAT
ATCCAGAAGGCATTCCCCAACCTCGACCCCAAACTGCTCGGCCACGATATCGCCTATCCCGCGATGCTGCGCTTCCTGCC
GGCCGGCTGGATCGGGCTCATGCTCGGCGGGCTGATTGCAGCCAATTCGTCCACCATCCTGACCCACCTGAATTGGGGCG
CGTCCTATCTCGTCCACGATTTTTACCGCCGCTTCATCACCCGCGACGCTTCCGAGAAGCACTACGTGAAGGCCGGGCGC
TATGCCACCGTATTGCTCTTTGTCCTGTCCTCGGCGATGGTCTTCGCGCTCGATACCGCGAAGGATAGCTTTAACCTCCT
GCTGGCCGTGGGCGCCGGAACCGGCCTCCTCTATATCCTGCGATGGTTCTGGTGGCGCATCAACGCGTGGTGTGAAATCG
TCGCCATGATCAGCTCCTTTGCGGTCGCGCTCATCTTCCTTGTCCTCGCCAAGAACGGCATCGTCTATGGCTTCTCGCAG
CAGCTAATCATCGGCGTAGCTCTTACTACCGTCAGTTGGATCGCCGCCGCCTACCTTTCACCCCAAACCGATGACCGCGT
GCTGGTCGGTTTCTATGAGAAGGTTCGCCCGTTCGGCCCCGGCTGGCGGCGCATTCAAGCCAAATCGAGTGCGCCTGTTG
TGGAAGGAGATAATTATCCCCTGGCTCTCCTCGGATGGATTATGGGCGTTACCATGATATGGTCGGCCCTGTTCACCGTG
GGTAATTTCCTGTATGGCCGCACCAACTACGCCCTTATACTTGGCGTCATTTTTGTGATCAGCGGCTCCATCGTAATTCA
GGTGGTTAAGAAACTCTGGAAGTAG

Upstream 100 bases:

>100_bases
AAGTCCGGGAAGGCCTCATCGAGCGCTTCTATTCCGGAGCCGCCGGTCATATTTACGAAGCAGAACCGGGCCCCGGCGCT
GTAAACTCGTAGTTTCCTAT

Downstream 100 bases:

>100_bases
GAATAGAGAATGGACAAGACTTCAAGGCGTGATTTATTGAAGCTGGCGTCTCTGGCCGGAATCGGCGCTGGCCTCGCGCG
CTCACAGGGCTCATCCAAAA

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MQLHSLDWIIAFLSVAVCFVPALFFGKRSGKSTAEFFASGRSVPWWLAGISMVATTFSSDTPNLVANFVRTQGVAGNWQW
WAFTLTGVSTVFFFARLWRRSGVLTDLEFYELRYSGKAASAVRGFRAVYLGLFFNCIIMATVNLAACKIAAILFGLPRWE
TLLAVGLLNVIFATHSGLWGVLVIDMIQFFIKMSAVIAAAYFAVTLPQVGGLSGMVDKLSHVRGPGGLNYLSLLPDFTNN
WDLAVAIFIIPIAIQWWSVWYPGAEPGGGSYIAQRMLASKSEKDALGGTLFFNVAHYVLRPWPWILVGLCSIIVYPQLSD
IQKAFPNLDPKLLGHDIAYPAMLRFLPAGWIGLMLGGLIAANSSTILTHLNWGASYLVHDFYRRFITRDASEKHYVKAGR
YATVLLFVLSSAMVFALDTAKDSFNLLLAVGAGTGLLYILRWFWWRINAWCEIVAMISSFAVALIFLVLAKNGIVYGFSQ
QLIIGVALTTVSWIAAAYLSPQTDDRVLVGFYEKVRPFGPGWRRIQAKSSAPVVEGDNYPLALLGWIMGVTMIWSALFTV
GNFLYGRTNYALILGVIFVISGSIVIQVVKKLWK

Sequences:

>Translated_594_residues
MQLHSLDWIIAFLSVAVCFVPALFFGKRSGKSTAEFFASGRSVPWWLAGISMVATTFSSDTPNLVANFVRTQGVAGNWQW
WAFTLTGVSTVFFFARLWRRSGVLTDLEFYELRYSGKAASAVRGFRAVYLGLFFNCIIMATVNLAACKIAAILFGLPRWE
TLLAVGLLNVIFATHSGLWGVLVIDMIQFFIKMSAVIAAAYFAVTLPQVGGLSGMVDKLSHVRGPGGLNYLSLLPDFTNN
WDLAVAIFIIPIAIQWWSVWYPGAEPGGGSYIAQRMLASKSEKDALGGTLFFNVAHYVLRPWPWILVGLCSIIVYPQLSD
IQKAFPNLDPKLLGHDIAYPAMLRFLPAGWIGLMLGGLIAANSSTILTHLNWGASYLVHDFYRRFITRDASEKHYVKAGR
YATVLLFVLSSAMVFALDTAKDSFNLLLAVGAGTGLLYILRWFWWRINAWCEIVAMISSFAVALIFLVLAKNGIVYGFSQ
QLIIGVALTTVSWIAAAYLSPQTDDRVLVGFYEKVRPFGPGWRRIQAKSSAPVVEGDNYPLALLGWIMGVTMIWSALFTV
GNFLYGRTNYALILGVIFVISGSIVIQVVKKLWK
>Mature_594_residues
MQLHSLDWIIAFLSVAVCFVPALFFGKRSGKSTAEFFASGRSVPWWLAGISMVATTFSSDTPNLVANFVRTQGVAGNWQW
WAFTLTGVSTVFFFARLWRRSGVLTDLEFYELRYSGKAASAVRGFRAVYLGLFFNCIIMATVNLAACKIAAILFGLPRWE
TLLAVGLLNVIFATHSGLWGVLVIDMIQFFIKMSAVIAAAYFAVTLPQVGGLSGMVDKLSHVRGPGGLNYLSLLPDFTNN
WDLAVAIFIIPIAIQWWSVWYPGAEPGGGSYIAQRMLASKSEKDALGGTLFFNVAHYVLRPWPWILVGLCSIIVYPQLSD
IQKAFPNLDPKLLGHDIAYPAMLRFLPAGWIGLMLGGLIAANSSTILTHLNWGASYLVHDFYRRFITRDASEKHYVKAGR
YATVLLFVLSSAMVFALDTAKDSFNLLLAVGAGTGLLYILRWFWWRINAWCEIVAMISSFAVALIFLVLAKNGIVYGFSQ
QLIIGVALTTVSWIAAAYLSPQTDDRVLVGFYEKVRPFGPGWRRIQAKSSAPVVEGDNYPLALLGWIMGVTMIWSALFTV
GNFLYGRTNYALILGVIFVISGSIVIQVVKKLWK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=399, Percent_Identity=24.3107769423559, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 65693; Mature: 65693

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]