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The map label for this gene is 116625630

Identifier: 116625630

GI number: 116625630

Start: 8251401

End: 8252462

Strand: Direct

Name: 116625630

Synonym: Acid_6579

Alternate gene names: NA

Gene position: 8251401-8252462 (Clockwise)

Preceding gene: 116625628

Following gene: 116625631

Centisome position: 82.8

GC content: 65.25

Gene sequence:

>1062_bases
TTGCGATTTTCCAGCATGATTACAGCGGTGGATGCCCATGCCTGCGGCGAACCCGGGCGCGTCATTACGGGCGGAGTGCT
CGACGTACCTGGCAAGACGATGTTCGACAAGAAGAACTGGCTCGCCGAGCATGCCGACCACATTCGCCTCCGCATGCTGC
GTGAACCGCGCGGGTATCCCGCCTCCAACTGCAACCTCATCCTCCCCTCCAACCACCCCGACGCCGACGCCGGCTTCGTC
ATCATGGAGCAGGTGGAGTACCCGCCGATGTCCGGCACCAACACCATCTGCGTCGTCACCGTCCTCATCGAAACCGGCAT
GGTGAAGGCCACCGAACCCGTCACCCAGCTCAAGCTCGAAACGCCCGCCGGCCTGATCGCGGTCGATGCCGAAGTGCATC
ATGGCAAGGTCCGCAAGGTGACCTTCCGCAACGTTCCCGCCTTCGCCACGCACCTCGATGCCAAGATCGAAGTCCGTGGA
CTCGGCACCGTGACCGTCGATGTCGCCTATGGCGGCATGTTCTACGCGATCGCCGACGCCGCGCCGCTTGGCCTCGCGCT
CGCCGCCGATGAAGCCCGCGACATCGTCCGGGTCGCCGAGATGATCAAGGCCGCCACGCAGGAGCAGTTGCCCGTCACTC
ATCCCGAGAACGCCGGGATCTCCGGCGTCACCATCGCCCAGCTTTCCGGCCCGCCATCGCGCCCCGGCGCGCACCTCCGG
AATACCGTCGTGGTCTCCACCGGTGCGCTCGATTGGTCGCGTCCGGAATCGTGGACCGGAGCGCTCGATCGTTCGCCCTG
CGGCACCGGCACCTGCGCCAAGATGGCCGCCCTCTACGCCAAGGGCCAACTCGGGCTCTATGAGGATTTCGTCCATGAGG
GCATTCTCGGGACCACATTCACCGGCCGCCTCCTGGAAGAGACGCGCGTCGGACCGTACGCCGCCGTCGTGCCGTCACTC
TCCGGCCAAGCCTGGATCACCGGCTTTGCGCAGTACGTGCTGGACCCGGAGGACCCGTTTCCGAACGGTTTCACGGTTGG
GGATATTTGGGGGAAAGCGTAA

Upstream 100 bases:

>100_bases
GATGACCTTTCTCTCCGCGGCCAGCGGAAGAGCGAGCAAAATGAGAATCGCACAGAGGTTTCGCATAGAGCGCAATGTAG
CATATAGGGTGAGGTGAAGA

Downstream 100 bases:

>100_bases
TGATCACCACTGGATTGAAAGACACCGGATTGAAAGACCAGGTAGTCGTTGTCACCGGAGCCGCGGCAGGCATCGGACTC
GCCACCGCGCGGCGTTTTGC

Product: proline racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRFSSMITAVDAHACGEPGRVITGGVLDVPGKTMFDKKNWLAEHADHIRLRMLREPRGYPASNCNLILPSNHPDADAGFV
IMEQVEYPPMSGTNTICVVTVLIETGMVKATEPVTQLKLETPAGLIAVDAEVHHGKVRKVTFRNVPAFATHLDAKIEVRG
LGTVTVDVAYGGMFYAIADAAPLGLALAADEARDIVRVAEMIKAATQEQLPVTHPENAGISGVTIAQLSGPPSRPGAHLR
NTVVVSTGALDWSRPESWTGALDRSPCGTGTCAKMAALYAKGQLGLYEDFVHEGILGTTFTGRLLEETRVGPYAAVVPSL
SGQAWITGFAQYVLDPEDPFPNGFTVGDIWGKA

Sequences:

>Translated_353_residues
MRFSSMITAVDAHACGEPGRVITGGVLDVPGKTMFDKKNWLAEHADHIRLRMLREPRGYPASNCNLILPSNHPDADAGFV
IMEQVEYPPMSGTNTICVVTVLIETGMVKATEPVTQLKLETPAGLIAVDAEVHHGKVRKVTFRNVPAFATHLDAKIEVRG
LGTVTVDVAYGGMFYAIADAAPLGLALAADEARDIVRVAEMIKAATQEQLPVTHPENAGISGVTIAQLSGPPSRPGAHLR
NTVVVSTGALDWSRPESWTGALDRSPCGTGTCAKMAALYAKGQLGLYEDFVHEGILGTTFTGRLLEETRVGPYAAVVPSL
SGQAWITGFAQYVLDPEDPFPNGFTVGDIWGKA
>Mature_353_residues
MRFSSMITAVDAHACGEPGRVITGGVLDVPGKTMFDKKNWLAEHADHIRLRMLREPRGYPASNCNLILPSNHPDADAGFV
IMEQVEYPPMSGTNTICVVTVLIETGMVKATEPVTQLKLETPAGLIAVDAEVHHGKVRKVTFRNVPAFATHLDAKIEVRG
LGTVTVDVAYGGMFYAIADAAPLGLALAADEARDIVRVAEMIKAATQEQLPVTHPENAGISGVTIAQLSGPPSRPGAHLR
NTVVVSTGALDWSRPESWTGALDRSPCGTGTCAKMAALYAKGQLGLYEDFVHEGILGTTFTGRLLEETRVGPYAAVVPSL
SGQAWITGFAQYVLDPEDPFPNGFTVGDIWGKA

Specific function: Unknown

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=356, Percent_Identity=31.4606741573034, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: NA

Molecular weight: Translated: 37627; Mature: 37627

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSSMITAVDAHACGEPGRVITGGVLDVPGKTMFDKKNWLAEHADHIRLRMLREPRGYP
CCHHHHHHHHHHHHCCCCCCEEECCEEECCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCC
ASNCNLILPSNHPDADAGFVIMEQVEYPPMSGTNTICVVTVLIETGMVKATEPVTQLKLE
CCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCHHEEEEE
TPAGLIAVDAEVHHGKVRKVTFRNVPAFATHLDAKIEVRGLGTVTVDVAYGGMFYAIADA
CCCCEEEEECEECCCEEEEEEECCCCHHHHCCCCEEEEEECCEEEEEEEECCEEEEEECC
APLGLALAADEARDIVRVAEMIKAATQEQLPVTHPENAGISGVTIAQLSGPPSRPGAHLR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
NTVVVSTGALDWSRPESWTGALDRSPCGTGTCAKMAALYAKGQLGLYEDFVHEGILGTTF
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCH
TGRLLEETRVGPYAAVVPSLSGQAWITGFAQYVLDPEDPFPNGFTVGDIWGKA
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MRFSSMITAVDAHACGEPGRVITGGVLDVPGKTMFDKKNWLAEHADHIRLRMLREPRGYP
CCHHHHHHHHHHHHCCCCCCEEECCEEECCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCC
ASNCNLILPSNHPDADAGFVIMEQVEYPPMSGTNTICVVTVLIETGMVKATEPVTQLKLE
CCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCHHEEEEE
TPAGLIAVDAEVHHGKVRKVTFRNVPAFATHLDAKIEVRGLGTVTVDVAYGGMFYAIADA
CCCCEEEEECEECCCEEEEEEECCCCHHHHCCCCEEEEEECCEEEEEEEECCEEEEEECC
APLGLALAADEARDIVRVAEMIKAATQEQLPVTHPENAGISGVTIAQLSGPPSRPGAHLR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
NTVVVSTGALDWSRPESWTGALDRSPCGTGTCAKMAALYAKGQLGLYEDFVHEGILGTTF
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCH
TGRLLEETRVGPYAAVVPSLSGQAWITGFAQYVLDPEDPFPNGFTVGDIWGKA
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]