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The map label for this gene is 116625558

Identifier: 116625558

GI number: 116625558

Start: 8154215

End: 8155933

Strand: Direct

Name: 116625558

Synonym: Acid_6505

Alternate gene names: NA

Gene position: 8154215-8155933 (Clockwise)

Preceding gene: 116625554

Following gene: 116625562

Centisome position: 81.82

GC content: 65.79

Gene sequence:

>1719_bases
ATGACAGATTCGCGAAAACTAACAGCGGGCGTTTCCGGAGTGCTGTTGGCCGGAGCGCTGGCCGCGCTCTGGTGGACGCG
TGAAACCGCGCCCAATCGTGCGCCTGCCGCCTCCGCGTCCGCAATCGACCGCCGCTTGCTGGACACTGCCCGGCAGTTGG
CCGCGATTGCCGAAACCCCCGCGGAGCAGGAGCTCTACCGCCAGTCCAGCCGGCTGGCCGACCACGAGCTCGACCAGTCC
TTCGCCACCGCCGTGCGTGAAGCCGCCGCGCGCAAACCCCCGGCCTCAGGCCCGCTGCAGCAGGCCAACGCACGGGTTAC
CCAGACCCGCGCGCGCGTTGCGGCCGACCAGGAGCGGATCGCCAAACTCAGCAAAACCGCGGCGTCGAACGACGAAACCA
CGGGGCAGCTCGAAGTCGCCAAAGCCCAACTTGCCCTGGATCAGGACGAGTTCGAAGACGCGCAGCTCGATCTCGCTCGC
CAGGGTGGCGACGAACGCGCCCAATTGGAGCGCGCCGCGCAGGAGCATGCCGAGGCGCAGAAAGAACCTGCCCCGGTGAA
GCCGGCGCCGCTGCCCGGCACTGAAACCCTGTCAGGTCAGATCAGCGCGTGGATGGAATTGAACGATCGCCAGAGCCGGC
TCGAAGCGGCGCGCCAGCAGGCGGCGCGGCATGCGGCGACGCTCGAGCGCGAGCACAACAGTCTGGAGGCGATCCTCGAG
AAGAAACCGGCCGCCGCGCCCGCAGCCTCCACCGATGCCGGCGATGACGCGGACCTGGAGGAAGATCCGGCCGCCATGGT
GGCGCGCCTGCACAACCTCTCCGACCAGCGCAAGACTTTGATGGAGCTCGACCGCCGTATTCAGGACGCGCAGCAGCTCG
CCGAAACCTACAAGGGCTGGAGCGGCATCGTGGATTCCCGCTCGCGCGGTGTACTGCATCTGCTGCTGCGCTCGGTGGCC
GCGATCCTCGGTGTCCTGCTTGCCGTAGTGCTGCTCGAACTCGGCGTTCGCCGGCGTCTTCACGACCAGAAAGATCGTCG
CCGCATACACCAGCAGCGTTTCCTCATCACCCTCGGAATCCGCGCCGCGGCCGCCATCGCCGTGCTCTTCATCATCTTCG
GTCTGCCCGGTCAGATGCCAACCATCATCGGGCTCGCCACCGCCGGAATGACCGTCGTACTCAGGGATTTCATAGTCGCC
TTCTTCGGCTGGTTCGTGCTCATCGGCCGCCACGGCGTGCGCGTCGGGGATTGGGTGGAAATCAAGGGCGTGGGCGGCGA
AGTCATCGAAGTCGGAGTCTTCAAAACGGTGCTGCTGGAGATGGGCACGGGCCACCCCACCGGCCGGCGAGTCTCATTCA
TGAACGGCTACGCCATCGAAGGTGTCTACTTCAACTTCTCCACCGCGGGACAGTGGCTGTGGGACGAACTGCAGGTCACC
GTGCCCGCTGGCGCCGATCCCTACCGCACCGCGGAACGCATTCGAGAGGTGGTGGAAAAGGAAACCGGCGACGAAGCCGA
ACTGGCCGAACAGGATTGGGAGCGCATCACGAAACAATATGGGACCCGCGCCTTCTCCGCAAGACCTGCGTCCGATCTGC
GCCCCGTCGCCGGGGGCCTGGACGTCCACATTCGCTATATCACCCGCGGTCCGCAGCGCCACGAAGTAAAATCGCGCCTC
TTCAAGGAAATCGTGGCGTTGCTGCACAGCACTGCTTGA

Upstream 100 bases:

>100_bases
CCGCAGCCATGGCTGCCACCAGCAAGGCCATCAGGACTCCGAGAAGGATCGCAATTCGTTTCATGGTCTTCGAGTGTACT
ACCTTCGAAAGAGAGCCTTC

Downstream 100 bases:

>100_bases
TTGCGTTTTTTCTTATCCGCGTTTATCTGCGTTTATCTGCGGCCAATTCTGTTTCTTGAAGAGGTTAATCCCCCGCCGCG
CTATCCGCTCGCGGCGTGAA

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: MscS Mechanosensitive Ion Channel

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTDSRKLTAGVSGVLLAGALAALWWTRETAPNRAPAASASAIDRRLLDTARQLAAIAETPAEQELYRQSSRLADHELDQS
FATAVREAAARKPPASGPLQQANARVTQTRARVAADQERIAKLSKTAASNDETTGQLEVAKAQLALDQDEFEDAQLDLAR
QGGDERAQLERAAQEHAEAQKEPAPVKPAPLPGTETLSGQISAWMELNDRQSRLEAARQQAARHAATLEREHNSLEAILE
KKPAAAPAASTDAGDDADLEEDPAAMVARLHNLSDQRKTLMELDRRIQDAQQLAETYKGWSGIVDSRSRGVLHLLLRSVA
AILGVLLAVVLLELGVRRRLHDQKDRRRIHQQRFLITLGIRAAAAIAVLFIIFGLPGQMPTIIGLATAGMTVVLRDFIVA
FFGWFVLIGRHGVRVGDWVEIKGVGGEVIEVGVFKTVLLEMGTGHPTGRRVSFMNGYAIEGVYFNFSTAGQWLWDELQVT
VPAGADPYRTAERIREVVEKETGDEAELAEQDWERITKQYGTRAFSARPASDLRPVAGGLDVHIRYITRGPQRHEVKSRL
FKEIVALLHSTA

Sequences:

>Translated_572_residues
MTDSRKLTAGVSGVLLAGALAALWWTRETAPNRAPAASASAIDRRLLDTARQLAAIAETPAEQELYRQSSRLADHELDQS
FATAVREAAARKPPASGPLQQANARVTQTRARVAADQERIAKLSKTAASNDETTGQLEVAKAQLALDQDEFEDAQLDLAR
QGGDERAQLERAAQEHAEAQKEPAPVKPAPLPGTETLSGQISAWMELNDRQSRLEAARQQAARHAATLEREHNSLEAILE
KKPAAAPAASTDAGDDADLEEDPAAMVARLHNLSDQRKTLMELDRRIQDAQQLAETYKGWSGIVDSRSRGVLHLLLRSVA
AILGVLLAVVLLELGVRRRLHDQKDRRRIHQQRFLITLGIRAAAAIAVLFIIFGLPGQMPTIIGLATAGMTVVLRDFIVA
FFGWFVLIGRHGVRVGDWVEIKGVGGEVIEVGVFKTVLLEMGTGHPTGRRVSFMNGYAIEGVYFNFSTAGQWLWDELQVT
VPAGADPYRTAERIREVVEKETGDEAELAEQDWERITKQYGTRAFSARPASDLRPVAGGLDVHIRYITRGPQRHEVKSRL
FKEIVALLHSTA
>Mature_571_residues
TDSRKLTAGVSGVLLAGALAALWWTRETAPNRAPAASASAIDRRLLDTARQLAAIAETPAEQELYRQSSRLADHELDQSF
ATAVREAAARKPPASGPLQQANARVTQTRARVAADQERIAKLSKTAASNDETTGQLEVAKAQLALDQDEFEDAQLDLARQ
GGDERAQLERAAQEHAEAQKEPAPVKPAPLPGTETLSGQISAWMELNDRQSRLEAARQQAARHAATLEREHNSLEAILEK
KPAAAPAASTDAGDDADLEEDPAAMVARLHNLSDQRKTLMELDRRIQDAQQLAETYKGWSGIVDSRSRGVLHLLLRSVAA
ILGVLLAVVLLELGVRRRLHDQKDRRRIHQQRFLITLGIRAAAAIAVLFIIFGLPGQMPTIIGLATAGMTVVLRDFIVAF
FGWFVLIGRHGVRVGDWVEIKGVGGEVIEVGVFKTVLLEMGTGHPTGRRVSFMNGYAIEGVYFNFSTAGQWLWDELQVTV
PAGADPYRTAERIREVVEKETGDEAELAEQDWERITKQYGTRAFSARPASDLRPVAGGLDVHIRYITRGPQRHEVKSRLF
KEIVALLHSTA

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 62669; Mature: 62538

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSRKLTAGVSGVLLAGALAALWWTRETAPNRAPAASASAIDRRLLDTARQLAAIAETP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEQELYRQSSRLADHELDQSFATAVREAAARKPPASGPLQQANARVTQTRARVAADQERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKLSKTAASNDETTGQLEVAKAQLALDQDEFEDAQLDLARQGGDERAQLERAAQEHAEAQ
HHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KEPAPVKPAPLPGTETLSGQISAWMELNDRQSRLEAARQQAARHAATLEREHNSLEAILE
CCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKPAAAPAASTDAGDDADLEEDPAAMVARLHNLSDQRKTLMELDRRIQDAQQLAETYKGW
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
SGIVDSRSRGVLHLLLRSVAAILGVLLAVVLLELGVRRRLHDQKDRRRIHQQRFLITLGI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RAAAAIAVLFIIFGLPGQMPTIIGLATAGMTVVLRDFIVAFFGWFVLIGRHGVRVGDWVE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IKGVGGEVIEVGVFKTVLLEMGTGHPTGRRVSFMNGYAIEGVYFNFSTAGQWLWDELQVT
EECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEECCCCCHHHHHHHEEE
VPAGADPYRTAERIREVVEKETGDEAELAEQDWERITKQYGTRAFSARPASDLRPVAGGL
ECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DVHIRYITRGPQRHEVKSRLFKEIVALLHSTA
EEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDSRKLTAGVSGVLLAGALAALWWTRETAPNRAPAASASAIDRRLLDTARQLAAIAETP
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEQELYRQSSRLADHELDQSFATAVREAAARKPPASGPLQQANARVTQTRARVAADQERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKLSKTAASNDETTGQLEVAKAQLALDQDEFEDAQLDLARQGGDERAQLERAAQEHAEAQ
HHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KEPAPVKPAPLPGTETLSGQISAWMELNDRQSRLEAARQQAARHAATLEREHNSLEAILE
CCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKPAAAPAASTDAGDDADLEEDPAAMVARLHNLSDQRKTLMELDRRIQDAQQLAETYKGW
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
SGIVDSRSRGVLHLLLRSVAAILGVLLAVVLLELGVRRRLHDQKDRRRIHQQRFLITLGI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RAAAAIAVLFIIFGLPGQMPTIIGLATAGMTVVLRDFIVAFFGWFVLIGRHGVRVGDWVE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IKGVGGEVIEVGVFKTVLLEMGTGHPTGRRVSFMNGYAIEGVYFNFSTAGQWLWDELQVT
EECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEECCCCCHHHHHHHEEE
VPAGADPYRTAERIREVVEKETGDEAELAEQDWERITKQYGTRAFSARPASDLRPVAGGL
ECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DVHIRYITRGPQRHEVKSRLFKEIVALLHSTA
EEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA