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The map label for this gene is mntH [H]

Identifier: 116625510

GI number: 116625510

Start: 8093394

End: 8094656

Strand: Direct

Name: mntH [H]

Synonym: Acid_6457

Alternate gene names: 116625510

Gene position: 8093394-8094656 (Clockwise)

Preceding gene: 116625509

Following gene: 116625511

Centisome position: 81.21

GC content: 64.05

Gene sequence:

>1263_bases
ATGAGACAACGGCGTAGAACGATCGGGGAATTCTTCGGCCAGCTGGGCCCCGGGCTGATCACGGGGGCGGCGGACGATGA
CCCGTCGGGGATCGCGACCTACTCGGTGAGCGGCGCGGGCTTCGGGTACAGCCCGCTGTGGACGGCGCTTTTCTGTTTTC
CGCTGATGGTCGCAGTGCAAATGATGTGCGCGCGGCTGGGCATGGTCAGCGGGCGCGGCCTGGCGGCGGTGGTGCGGCGC
CGCTATTCGCGCTGGGTGCTGTGGGGCGCCTGCCTGTTGCTGACGGTGGCCAACGTAATCAACATCGGTGCCGACCTGGG
CGGTATGGCGGACGCTACCGAGATGGTCACCGGCATACCCTCCTGGTGGCTGACTCCGTTCTATGCGGCGTTGATCATTG
CGGTGATGATGTGGAGCTCATACCGGGCCATCGCGCGCGTGTTCAAGTGGCTCACGCTGGTGCTGTTCGCGTACGTGATC
ACGGCGTTCGTGGTGCATCCGGATTGGCGCGCGGTGCTGCATGCGACTTTTGTGCCGCAGATCGTGTGGTCTTCGGAATA
TCTCTCGGTGCTGGTGGGAATCCTGGGGACGACAATTTCGCCGTACCTGTTCTTCTGGCAGGCAGCGCAGGAAGTGGAGG
AAGAGCGCGCCGCTGGACGAACCACGGTAGCGCAGCGCCGCGGGGCGACCGCGAAGGAGCTGCGGGAATCGCGCAACGAT
GTGATGATCGGGATGTTCTTCTCCAATTTCGTGATGTACTTCATCATCCTGACCACGGCATCCACGCTGCATGCGCACGG
AGTGACGCACATCGCCACCGCGAAGCAGGCCGCGGAGGCGCTGCGGCCGCTGGCCGGAGCGGGCGCGTACTGGTTGTTCA
CGCTGGGATTGATCGGCACCGGGATGCTCGGCGTGCCGGTGCTGGCCGGGTCGAGCGCGTACGCGATCGCGGAGGCGATG
AACTGGATGGGGTCGCTGGACCGGAAACCGAAGCTGGCCGTGAAATTCTACAGCGTCCTGGGCGTGGCGATGGCGCTCGG
CCTGGCGTTGGATTACGCGGGGCTGGATGCAGTGAAGATGCTGTTCTGGTCGGCGGTCGCGAACGGAGTGCTTGCGCCGC
CGCTGGTAGTGATTGTGGTTCTGCTCACAACGGACTCGAGCGTCATGGGCGAGCATGTAAATTCTCCTCTGCTCAAATGG
CTGGGGTGGACGACAGCAGTGGTGATGACCGCAGCGGCAGTAGCGATGATGCTCGCAGGATAG

Upstream 100 bases:

>100_bases
GATACCGAGTCCAAGATCCGCGAAGTGGTTCCCGAGATCCGGGGGATGGTAAAGGAAGGGCTTGTCGTCCTGCTGGACGC
CGAAGTGGTGGATCCGGCGG

Downstream 100 bases:

>100_bases
AGGCCGGCGCGGTAAAATTGACAGTTTGCATGTCTAGATTCCACACCCCGATTACCGATGAGATGGCGGATTATGTCCGC
GAGGTCAGCCTGCGCGAACC

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MRQRRRTIGEFFGQLGPGLITGAADDDPSGIATYSVSGAGFGYSPLWTALFCFPLMVAVQMMCARLGMVSGRGLAAVVRR
RYSRWVLWGACLLLTVANVINIGADLGGMADATEMVTGIPSWWLTPFYAALIIAVMMWSSYRAIARVFKWLTLVLFAYVI
TAFVVHPDWRAVLHATFVPQIVWSSEYLSVLVGILGTTISPYLFFWQAAQEVEEERAAGRTTVAQRRGATAKELRESRND
VMIGMFFSNFVMYFIILTTASTLHAHGVTHIATAKQAAEALRPLAGAGAYWLFTLGLIGTGMLGVPVLAGSSAYAIAEAM
NWMGSLDRKPKLAVKFYSVLGVAMALGLALDYAGLDAVKMLFWSAVANGVLAPPLVVIVVLLTTDSSVMGEHVNSPLLKW
LGWTTAVVMTAAAVAMMLAG

Sequences:

>Translated_420_residues
MRQRRRTIGEFFGQLGPGLITGAADDDPSGIATYSVSGAGFGYSPLWTALFCFPLMVAVQMMCARLGMVSGRGLAAVVRR
RYSRWVLWGACLLLTVANVINIGADLGGMADATEMVTGIPSWWLTPFYAALIIAVMMWSSYRAIARVFKWLTLVLFAYVI
TAFVVHPDWRAVLHATFVPQIVWSSEYLSVLVGILGTTISPYLFFWQAAQEVEEERAAGRTTVAQRRGATAKELRESRND
VMIGMFFSNFVMYFIILTTASTLHAHGVTHIATAKQAAEALRPLAGAGAYWLFTLGLIGTGMLGVPVLAGSSAYAIAEAM
NWMGSLDRKPKLAVKFYSVLGVAMALGLALDYAGLDAVKMLFWSAVANGVLAPPLVVIVVLLTTDSSVMGEHVNSPLLKW
LGWTTAVVMTAAAVAMMLAG
>Mature_420_residues
MRQRRRTIGEFFGQLGPGLITGAADDDPSGIATYSVSGAGFGYSPLWTALFCFPLMVAVQMMCARLGMVSGRGLAAVVRR
RYSRWVLWGACLLLTVANVINIGADLGGMADATEMVTGIPSWWLTPFYAALIIAVMMWSSYRAIARVFKWLTLVLFAYVI
TAFVVHPDWRAVLHATFVPQIVWSSEYLSVLVGILGTTISPYLFFWQAAQEVEEERAAGRTTVAQRRGATAKELRESRND
VMIGMFFSNFVMYFIILTTASTLHAHGVTHIATAKQAAEALRPLAGAGAYWLFTLGLIGTGMLGVPVLAGSSAYAIAEAM
NWMGSLDRKPKLAVKFYSVLGVAMALGLALDYAGLDAVKMLFWSAVANGVLAPPLVVIVVLLTTDSSVMGEHVNSPLLKW
LGWTTAVVMTAAAVAMMLAG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Escherichia coli, GI1788736, Length=403, Percent_Identity=24.5657568238213, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323062, Length=323, Percent_Identity=22.6006191950464, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45329; Mature: 45329

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]