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The map label for this gene is 116625419

Identifier: 116625419

GI number: 116625419

Start: 7982696

End: 7984039

Strand: Reverse

Name: 116625419

Synonym: Acid_6364

Alternate gene names: NA

Gene position: 7984039-7982696 (Counterclockwise)

Preceding gene: 116625420

Following gene: 116625414

Centisome position: 80.12

GC content: 67.56

Gene sequence:

>1344_bases
ATGCCAGCCGCGGCCCTGATCAGCGTACTCTCGCGCAGCCTGCTCGCCGGCGAGCAGGACGTCGATAGCCTTCACGCGCG
CGCGGCGCGAACCCTGGGGCGTCCATGGCGATGGATCCTTCCGTTGGCCGAGCGGTACGCGGCGGCATTCGGCGAAAGCG
GCGTGCGTCCGCGGCATCGCGACATTGTGGTGTTCCTGCGCAACGACGAGGGCTTCTCACGGGCACGCGCGAAGTACGGC
CGCCAAATCGAGATCGCCGAGTGGCTGACGGAACCGCCGCGCATGCAGCCCGCACCGGCAGCGCGAGGTTGGGACCTTCC
CGCGATCGAAACAGTGGGGGACTTGGCGGCCTGGCTCGTGGTGACCACGGACGAACTGGAGTGGTTCGCCGATCTCAAGG
AACTCGGCAACAAGCTTCGCAATTCGAAGCTGCGCCACTACCATTACGACATCCACAGCAAGCGCTCAGGCGGCGTGCGG
CTGATCGAGATCCCCAAGCCGCGGATCAAGGAGCTGCAGCGGCGGATTCTGCACGAAATCCTGGATGCCGTGCCGGTGCA
CGCGGCCGCTCACGGCTTCGTCCACGGGCGGTCGATCGCGACCTTCGCGGCGCCGCACACCGGCAAGGCGGCGGTGCTGC
GGCTTGATCTGGAGGACTTTTTCCCGGCCTTCCCCGCGGCCCGCGTACAGGCGCTGTTTCGAACCCTCGGCTATCCGGAA
CCGGTGGCAGACCGGCTGGGCGGGATCTGCGCTAACGCTGTAGCGCGGGAAGCGTGGAAGCTCCGGCCGCCGGAGATCGC
GTCGCGGGAGTGGGATGCGGCGCGAATTCTATACGGGCGGCCGCACCTGCCGCAGGGCGCGCCCACCTCGCCCGCGCTCG
CCAACCTCACGGCATACCGGCTGGACTGTCGTCTATCCGGCCTGGCTCGATCATCGGGCGCGGTGTACACGCGCTACGCC
GACGATCTCGCTTTCTCGGGCGGCGATGAGTTCGCGCGCGCCGTGGACCGCTTCCAGGCGCACGCCGCGGCTGTCGCGCT
GGAGGAAGGCTTCGGCGTCAATCACCATAAGACCCGGATCATGCGCCAGGGCGTCCGGCAGCATGTCGCCGGGGTCGTGG
TCAACCAGAAGGTCAATCTGCGGCGGCGTGATCTGGAGAGGCTGGAGGCGACGCTGACGAATTGCGTGCGCTTCGGTCCC
GAGGGGCAGAATCGCAAGGCGGTCGCGGATTTTCGTGCGCATCTGGAAGGACGCGTCGGCTTCGTGCAAATGGTGAATCC
GCTGCAGGGGGAGCGGATGAAGGCGCTGCTGCAGCAGATCCGGTGGGATCAGAGCGCGGGGTAA

Upstream 100 bases:

>100_bases
GCGTGGATTCGCCATTTCGTCGCGTGAGCGTCGCTGCACTGGCGAGCAGTTTAGCTCACGCAGAGCCTGACTCGTTGGAG
CCGGCACGCCGCCAATCGTT

Downstream 100 bases:

>100_bases
GCGGCGGCGATTTGTTTGCGGACGAACTCGAGATCCCGGCGGAAGGCGTTCAATTCGTTGGGTGACGAGTAGGCCACCTG
GATCGTGATCGGTCCGGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: Mx65-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPAAALISVLSRSLLAGEQDVDSLHARAARTLGRPWRWILPLAERYAAAFGESGVRPRHRDIVVFLRNDEGFSRARAKYG
RQIEIAEWLTEPPRMQPAPAARGWDLPAIETVGDLAAWLVVTTDELEWFADLKELGNKLRNSKLRHYHYDIHSKRSGGVR
LIEIPKPRIKELQRRILHEILDAVPVHAAAHGFVHGRSIATFAAPHTGKAAVLRLDLEDFFPAFPAARVQALFRTLGYPE
PVADRLGGICANAVAREAWKLRPPEIASREWDAARILYGRPHLPQGAPTSPALANLTAYRLDCRLSGLARSSGAVYTRYA
DDLAFSGGDEFARAVDRFQAHAAAVALEEGFGVNHHKTRIMRQGVRQHVAGVVVNQKVNLRRRDLERLEATLTNCVRFGP
EGQNRKAVADFRAHLEGRVGFVQMVNPLQGERMKALLQQIRWDQSAG

Sequences:

>Translated_447_residues
MPAAALISVLSRSLLAGEQDVDSLHARAARTLGRPWRWILPLAERYAAAFGESGVRPRHRDIVVFLRNDEGFSRARAKYG
RQIEIAEWLTEPPRMQPAPAARGWDLPAIETVGDLAAWLVVTTDELEWFADLKELGNKLRNSKLRHYHYDIHSKRSGGVR
LIEIPKPRIKELQRRILHEILDAVPVHAAAHGFVHGRSIATFAAPHTGKAAVLRLDLEDFFPAFPAARVQALFRTLGYPE
PVADRLGGICANAVAREAWKLRPPEIASREWDAARILYGRPHLPQGAPTSPALANLTAYRLDCRLSGLARSSGAVYTRYA
DDLAFSGGDEFARAVDRFQAHAAAVALEEGFGVNHHKTRIMRQGVRQHVAGVVVNQKVNLRRRDLERLEATLTNCVRFGP
EGQNRKAVADFRAHLEGRVGFVQMVNPLQGERMKALLQQIRWDQSAG
>Mature_446_residues
PAAALISVLSRSLLAGEQDVDSLHARAARTLGRPWRWILPLAERYAAAFGESGVRPRHRDIVVFLRNDEGFSRARAKYGR
QIEIAEWLTEPPRMQPAPAARGWDLPAIETVGDLAAWLVVTTDELEWFADLKELGNKLRNSKLRHYHYDIHSKRSGGVRL
IEIPKPRIKELQRRILHEILDAVPVHAAAHGFVHGRSIATFAAPHTGKAAVLRLDLEDFFPAFPAARVQALFRTLGYPEP
VADRLGGICANAVAREAWKLRPPEIASREWDAARILYGRPHLPQGAPTSPALANLTAYRLDCRLSGLARSSGAVYTRYAD
DLAFSGGDEFARAVDRFQAHAAAVALEEGFGVNHHKTRIMRQGVRQHVAGVVVNQKVNLRRRDLERLEATLTNCVRFGPE
GQNRKAVADFRAHLEGRVGFVQMVNPLQGERMKALLQQIRWDQSAG

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 49851; Mature: 49719

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAALISVLSRSLLAGEQDVDSLHARAARTLGRPWRWILPLAERYAAAFGESGVRPRHR
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DIVVFLRNDEGFSRARAKYGRQIEIAEWLTEPPRMQPAPAARGWDLPAIETVGDLAAWLV
CEEEEEECCCCHHHHHHHHCCEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHE
VTTDELEWFADLKELGNKLRNSKLRHYHYDIHSKRSGGVRLIEIPKPRIKELQRRILHEI
EECHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LDAVPVHAAAHGFVHGRSIATFAAPHTGKAAVLRLDLEDFFPAFPAARVQALFRTLGYPE
HHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHCCCCC
PVADRLGGICANAVAREAWKLRPPEIASREWDAARILYGRPHLPQGAPTSPALANLTAYR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHE
LDCRLSGLARSSGAVYTRYADDLAFSGGDEFARAVDRFQAHAAAVALEEGFGVNHHKTRI
EEHHHHCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MRQGVRQHVAGVVVNQKVNLRRRDLERLEATLTNCVRFGPEGQNRKAVADFRAHLEGRVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
FVQMVNPLQGERMKALLQQIRWDQSAG
HHHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PAAALISVLSRSLLAGEQDVDSLHARAARTLGRPWRWILPLAERYAAAFGESGVRPRHR
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
DIVVFLRNDEGFSRARAKYGRQIEIAEWLTEPPRMQPAPAARGWDLPAIETVGDLAAWLV
CEEEEEECCCCHHHHHHHHCCEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHE
VTTDELEWFADLKELGNKLRNSKLRHYHYDIHSKRSGGVRLIEIPKPRIKELQRRILHEI
EECHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LDAVPVHAAAHGFVHGRSIATFAAPHTGKAAVLRLDLEDFFPAFPAARVQALFRTLGYPE
HHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHCCCCC
PVADRLGGICANAVAREAWKLRPPEIASREWDAARILYGRPHLPQGAPTSPALANLTAYR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHE
LDCRLSGLARSSGAVYTRYADDLAFSGGDEFARAVDRFQAHAAAVALEEGFGVNHHKTRI
EEHHHHCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MRQGVRQHVAGVVVNQKVNLRRRDLERLEATLTNCVRFGPEGQNRKAVADFRAHLEGRVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCC
FVQMVNPLQGERMKALLQQIRWDQSAG
HHHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1689062 [H]