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The map label for this gene is cutA [H]

Identifier: 116625414

GI number: 116625414

Start: 7979053

End: 7979385

Strand: Reverse

Name: cutA [H]

Synonym: Acid_6359

Alternate gene names: 116625414

Gene position: 7979385-7979053 (Counterclockwise)

Preceding gene: 116625419

Following gene: 116625413

Centisome position: 80.07

GC content: 55.26

Gene sequence:

>333_bases
ATGACCGATAAGATTGTTGTCCTTAGCACCTGCGCCAGCGAGGCGGAGGCTGAAAAACTGGCGCGCGCGCTGGTTTCCGG
AGAACTGGCTGCCTGCGTCAACGTGGTACCTCAAATTCGCAGTTTTTATCGATGGAAGGGCGCACTGGAAACTGCGAACG
AATTCCTGCTGCTGATCAAGACATCCCGGAGTCTCTTCGACGCATTGAAGATCGAGCTCGAGAAGTTGCATCCCTATGAA
GTGCCGGAGGTGATCGCGCTGCCCATCGTGGCCGGGTCAGAAAATTATCTGAATTGGCTGGGGCATAATCTGCGAGCCGG
TGAGGCCGAATGA

Upstream 100 bases:

>100_bases
TTACATACGTGAATCTTGTCAGTGGCGCTTTCATGAGACGATAGGGCCTGGAACATAATATTAACATCGCTAACGGGATT
CACCCCTCACTTTTTTGGAA

Downstream 100 bases:

>100_bases
TCGCCCTGCTTTTCGACATGGATGGGGTGATTGTTGATTCGAACCCGATGCACCGGCAGGCCTGGGAGATTTTCAACCGG
CGCTACGGCGTGGAAACCAC

Product: CutA1 divalent ion tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MTDKIVVLSTCASEAEAEKLARALVSGELAACVNVVPQIRSFYRWKGALETANEFLLLIKTSRSLFDALKIELEKLHPYE
VPEVIALPIVAGSENYLNWLGHNLRAGEAE

Sequences:

>Translated_110_residues
MTDKIVVLSTCASEAEAEKLARALVSGELAACVNVVPQIRSFYRWKGALETANEFLLLIKTSRSLFDALKIELEKLHPYE
VPEVIALPIVAGSENYLNWLGHNLRAGEAE
>Mature_109_residues
TDKIVVLSTCASEAEAEKLARALVSGELAACVNVVPQIRSFYRWKGALETANEFLLLIKTSRSLFDALKIELEKLHPYEV
PEVIALPIVAGSENYLNWLGHNLRAGEAE

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=91, Percent_Identity=51.6483516483517, Blast_Score=99, Evalue=5e-22,
Organism=Homo sapiens, GI62526022, Length=91, Percent_Identity=51.6483516483517, Blast_Score=99, Evalue=5e-22,
Organism=Homo sapiens, GI7706244, Length=91, Percent_Identity=51.6483516483517, Blast_Score=99, Evalue=5e-22,
Organism=Homo sapiens, GI62526026, Length=91, Percent_Identity=51.6483516483517, Blast_Score=99, Evalue=6e-22,
Organism=Homo sapiens, GI62198241, Length=91, Percent_Identity=51.6483516483517, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1790579, Length=104, Percent_Identity=40.3846153846154, Blast_Score=86, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32565476, Length=106, Percent_Identity=31.1320754716981, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641937, Length=99, Percent_Identity=43.4343434343434, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12155; Mature: 12024

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKIVVLSTCASEAEAEKLARALVSGELAACVNVVPQIRSFYRWKGALETANEFLLLIK
CCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
TSRSLFDALKIELEKLHPYEVPEVIALPIVAGSENYLNWLGHNLRAGEAE
CCHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDKIVVLSTCASEAEAEKLARALVSGELAACVNVVPQIRSFYRWKGALETANEFLLLIK
CCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
TSRSLFDALKIELEKLHPYEVPEVIALPIVAGSENYLNWLGHNLRAGEAE
CCHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA