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The map label for this gene is yfjP [H]

Identifier: 116625362

GI number: 116625362

Start: 7924544

End: 7925146

Strand: Reverse

Name: yfjP [H]

Synonym: Acid_6307

Alternate gene names: 116625362

Gene position: 7925146-7924544 (Counterclockwise)

Preceding gene: 116625364

Following gene: 116625361

Centisome position: 79.52

GC content: 60.2

Gene sequence:

>603_bases
ATGAAACACGCGGTTCAGCACCTCCGAAAAAGCGATCCCGTACTTTCCGCCATTATCGAGCGGGTAGGCGCTTATGGTAT
CCAATTTCGCGAACCGGATTTCGAGACGCTCGTAAGATCTATCGTTTACCAGCAGTTGAGCGGGCGCGTCGCGAAGGTGA
TTCTTGACCGGCTCGTGGCCGCGGTTGGGCGCGAAGTCACGCCGGAAAAGATCCTGGCCCTACGGCCCGGGCGTATGCGC
AAATTGGGCCTTTCCACACAAAAGACCGCGTATATCCGGGACCTCGCCCGGCATACGCGGGACGGCAGGCTCGTCTTTAC
CGAACTGCCCGCACTCACCGACGAAGAGGTCATCGAGCGGCTCACACAGGTAAAGGGCATCGGAGTCTGGACCGCGCAGA
TGTTCCTGATGTTCGCCCTGCGCCGCCACGATGTGCTTCCCACCGGCGACCTGGGAGTCCGCAACGCCATCCGCAAGGCC
TATGATCTGGCTGAACTGCCCACTCCCGCCGAAATGGAGGAGCTTGCCCGAAATTGGCGCCCATGGTGCTCGGTCGCGAG
TTGGTATTTGTGGCGCAGCCTTGAAGGCCAAGCCGATCTGTAA

Upstream 100 bases:

>100_bases
ACTGGTCCTGCGCAAGCAGAAGGGAGCCAGCTATGAGAGCGGTGAGGATTCGCATGCCGTTACAATAGGCTTGACGTACC
TGTGGGGACGATTGTTTCAC

Downstream 100 bases:

>100_bases
GATTAATTTTCCACAAGATGTTGCAATTTCCTACGGCGAGCATATAATCAAATCAGATATTGAGATCCCGGATGCAGTTA
CATCCGACGTAGGAGACGAT

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKHAVQHLRKSDPVLSAIIERVGAYGIQFREPDFETLVRSIVYQQLSGRVAKVILDRLVAAVGREVTPEKILALRPGRMR
KLGLSTQKTAYIRDLARHTRDGRLVFTELPALTDEEVIERLTQVKGIGVWTAQMFLMFALRRHDVLPTGDLGVRNAIRKA
YDLAELPTPAEMEELARNWRPWCSVASWYLWRSLEGQADL

Sequences:

>Translated_200_residues
MKHAVQHLRKSDPVLSAIIERVGAYGIQFREPDFETLVRSIVYQQLSGRVAKVILDRLVAAVGREVTPEKILALRPGRMR
KLGLSTQKTAYIRDLARHTRDGRLVFTELPALTDEEVIERLTQVKGIGVWTAQMFLMFALRRHDVLPTGDLGVRNAIRKA
YDLAELPTPAEMEELARNWRPWCSVASWYLWRSLEGQADL
>Mature_200_residues
MKHAVQHLRKSDPVLSAIIERVGAYGIQFREPDFETLVRSIVYQQLSGRVAKVILDRLVAAVGREVTPEKILALRPGRMR
KLGLSTQKTAYIRDLARHTRDGRLVFTELPALTDEEVIERLTQVKGIGVWTAQMFLMFALRRHDVLPTGDLGVRNAIRKA
YDLAELPTPAEMEELARNWRPWCSVASWYLWRSLEGQADL

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=175, Percent_Identity=33.7142857142857, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22846; Mature: 22846

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHAVQHLRKSDPVLSAIIERVGAYGIQFREPDFETLVRSIVYQQLSGRVAKVILDRLVA
CCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGREVTPEKILALRPGRMRKLGLSTQKTAYIRDLARHTRDGRLVFTELPALTDEEVIER
HHCCCCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
LTQVKGIGVWTAQMFLMFALRRHDVLPTGDLGVRNAIRKAYDLAELPTPAEMEELARNWR
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
PWCSVASWYLWRSLEGQADL
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKHAVQHLRKSDPVLSAIIERVGAYGIQFREPDFETLVRSIVYQQLSGRVAKVILDRLVA
CCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGREVTPEKILALRPGRMRKLGLSTQKTAYIRDLARHTRDGRLVFTELPALTDEEVIER
HHCCCCCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
LTQVKGIGVWTAQMFLMFALRRHDVLPTGDLGVRNAIRKAYDLAELPTPAEMEELARNWR
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
PWCSVASWYLWRSLEGQADL
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]