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The map label for this gene is yycF [H]

Identifier: 116625339

GI number: 116625339

Start: 7892669

End: 7893382

Strand: Direct

Name: yycF [H]

Synonym: Acid_6284

Alternate gene names: 116625339

Gene position: 7892669-7893382 (Clockwise)

Preceding gene: 116625338

Following gene: 116625340

Centisome position: 79.2

GC content: 61.48

Gene sequence:

>714_bases
GTGTGGCTGATAGTCATGAAGAAAATCTTACTAATCGAGGACGACGCAGACCTCTTCTCGCTGCTGAAGTACAACCTGGA
GAAAGAGGGCTTCTCTTTGAGCGGTCAGCACACCGGGAAAGGCGCCATCGAGCTCTGCCGGCAGGTGCGGCCCGACCTCA
TTCTGCTGGATATCATGCTTCCCGATTCGGATGGCCTGGACATCTGCAAAGGCATCCGGAAAGATCCGGATCTGGCCGCG
ATACCCGTAATCTTCCTGACCGCGCGCGCCAGTGAAACCGACCGCATCGTGGGCCTGGAACTGGGCGCCAATGACTACGT
GGTCAAGCCGTTCTTCGTGCGCGAGCTGATTGCGCGAATCAAGCTGCAGTTCCGCAATCAGGCCACCCCGGCGCGCCTGC
TCGAAGCCGGCGGCGTGGAGCTGGACCGGACCAGCTGCCAGGTCCGGCTGAACGGTGTCCCGCTGGCGCTCACCGCCACC
GAATTCCGGCTCCTGGAATTCCTCATGAACCGGCCCGGCGTGGTCTTCAGCCGCGAGCAACTGTTGAATGCCGTCTGGGG
CCAGGATCGTGCGATTACGGACCGGGCAGTGGATGTCTACGTGCTCCGGTTGCGCCAGAAGGTGGAGAAAGATCCAGCCA
GCCCGATTCTGATTCACTCGGTGCGTGGTTTCGGGTACACCTTCGAGCCCCGGCGTTCCATGGCGGCGGTCTAG

Upstream 100 bases:

>100_bases
CTATTTCACTCTGCCGGTGGACGAAGCGGCACTCGGGCACGAAACCCTTAATCCCGAATTCACCGCCTCTTAACGGTCCC
GTAACGTTTGGCAGGGTACT

Downstream 100 bases:

>100_bases
AAGCTCCACACCGCCGCTATAATCGGCTGGTGAGGGAGCATGCATTCGTGAAGCTCAGACTGTTTGTTACCGTTCTTTCA
TGCGCGGCGGCCGCGTTCGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MWLIVMKKILLIEDDADLFSLLKYNLEKEGFSLSGQHTGKGAIELCRQVRPDLILLDIMLPDSDGLDICKGIRKDPDLAA
IPVIFLTARASETDRIVGLELGANDYVVKPFFVRELIARIKLQFRNQATPARLLEAGGVELDRTSCQVRLNGVPLALTAT
EFRLLEFLMNRPGVVFSREQLLNAVWGQDRAITDRAVDVYVLRLRQKVEKDPASPILIHSVRGFGYTFEPRRSMAAV

Sequences:

>Translated_237_residues
MWLIVMKKILLIEDDADLFSLLKYNLEKEGFSLSGQHTGKGAIELCRQVRPDLILLDIMLPDSDGLDICKGIRKDPDLAA
IPVIFLTARASETDRIVGLELGANDYVVKPFFVRELIARIKLQFRNQATPARLLEAGGVELDRTSCQVRLNGVPLALTAT
EFRLLEFLMNRPGVVFSREQLLNAVWGQDRAITDRAVDVYVLRLRQKVEKDPASPILIHSVRGFGYTFEPRRSMAAV
>Mature_237_residues
MWLIVMKKILLIEDDADLFSLLKYNLEKEGFSLSGQHTGKGAIELCRQVRPDLILLDIMLPDSDGLDICKGIRKDPDLAA
IPVIFLTARASETDRIVGLELGANDYVVKPFFVRELIARIKLQFRNQATPARLLEAGGVELDRTSCQVRLNGVPLALTAT
EFRLLEFLMNRPGVVFSREQLLNAVWGQDRAITDRAVDVYVLRLRQKVEKDPASPILIHSVRGFGYTFEPRRSMAAV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=41.4096916299559, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.7079646017699, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=39.1304347826087, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=37.7118644067797, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=38.4615384615385, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.1233480176211, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=39.5652173913043, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.6071428571429, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=37.8378378378378, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=37.10407239819, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=33.8912133891213, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=33.6244541484716, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=32.034632034632, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=30.6666666666667, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788550, Length=135, Percent_Identity=30.3703703703704, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26663; Mature: 26663

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLIVMKKILLIEDDADLFSLLKYNLEKEGFSLSGQHTGKGAIELCRQVRPDLILLDIML
CHHHEEEEEHEEECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEE
PDSDGLDICKGIRKDPDLAAIPVIFLTARASETDRIVGLELGANDYVVKPFFVRELIARI
CCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCEEECHHHHHHHHHHH
KLQFRNQATPARLLEAGGVELDRTSCQVRLNGVPLALTATEFRLLEFLMNRPGVVFSREQ
HHHHCCCCCHHHHHHCCCCEEECCEEEEEECCEEEEEEHHHHHHHHHHHCCCCCEEEHHH
LLNAVWGQDRAITDRAVDVYVLRLRQKVEKDPASPILIHSVRGFGYTFEPRRSMAAV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHCCCC
>Mature Secondary Structure
MWLIVMKKILLIEDDADLFSLLKYNLEKEGFSLSGQHTGKGAIELCRQVRPDLILLDIML
CHHHEEEEEHEEECCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEE
PDSDGLDICKGIRKDPDLAAIPVIFLTARASETDRIVGLELGANDYVVKPFFVRELIARI
CCCCCHHHHHHCCCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCEEECHHHHHHHHHHH
KLQFRNQATPARLLEAGGVELDRTSCQVRLNGVPLALTATEFRLLEFLMNRPGVVFSREQ
HHHHCCCCCHHHHHHCCCCEEECCEEEEEECCEEEEEEHHHHHHHHHHHCCCCCEEEHHH
LLNAVWGQDRAITDRAVDVYVLRLRQKVEKDPASPILIHSVRGFGYTFEPRRSMAAV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]