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The map label for this gene is ampH [C]

Identifier: 116625304

GI number: 116625304

Start: 7830383

End: 7831582

Strand: Direct

Name: ampH [C]

Synonym: Acid_6249

Alternate gene names: 116625304

Gene position: 7830383-7831582 (Clockwise)

Preceding gene: 116625295

Following gene: 116625311

Centisome position: 78.57

GC content: 61.25

Gene sequence:

>1200_bases
ATGAGTGAAACCCTGCAGCACATCGTCGAATCGGGCCAGCTTGCGGGAGCCGCTACCCTGGTCTGGAAGAACGGTACAGC
CCAAACGACATGTTTCGGGTGGCGGGATATTGAACGTAACCTGCCCGTCGAGCAGGACACCATCTTCAGAATCGCCTCGA
TGACGAAGCCGATTACCTCCGTAGCGGCACTCATGTTGGTGGATGAAGGCCGCATTGCGCTGAACGATCCCATCACTCGC
TATGCGCCGGAGTTTTCGCAGATGCGGGTGCTCCGGTCTCCTGGAAGTCCGCTCGACGAAACCGATCCCGCCGAACGGCT
GATTACGTTCGAAGACCTTCTCACCCACCGGGCGGGCCTGACTTATGGAGACCTTCATCGTTCCCCGATCATGCAGGCGT
ACCGCGGAGCGCTCGGCGGCGATATTGACACCGACGTCGCGCCGGACGACTGGATCGCGAAGCTTTCTCAATTGCCCTTG
ATCCACCAACCGGGAGAGATGTGGTCATACGGCCGCTCGACGGACCTGCTCGGACTGTTGATCGCCCGCATCGAAGGTGA
GCCGCTGCAGGCCGTGCTCAAGCGGCGCATCTTCGATCCGCTAGGCATGAAGGATACCAGTTTCCTTGTGCCTCCTGAAA
AGCGGGATCGGCGAGCGGCCGCTTACGGCTTTGACGATGAGGAGAAGTTGATCAAACGCGCAACGTGGGGCGGCGTGGTA
GTCGAAGAACGGCCGGTGGATATGGCATATGAATCAGGTGGCCAGGGGCTGTGGTCCACGGTCGATGACTATCTTCGTTT
CGCGCGATTGTTCCTGGGCGACGGTTCGGTGGATGGGGTGCGTTTATTACGTGCGGATACCCTGGCGCGCATGATGACCA
ACCAGCTGACCGAGGCCCAGCGGGCGAGTGCGCGGCTAATAGGGCAGAAGCTTTTCGCAGCCGGGCGAGGCTTCGGGCTG
GGCGTATCGGTGGTGCTGGAGCCGGACGCGAACGACATCATGCGGCGCGGCGGACCGGGAACCGTCAGTTGGGCGGGAGC
CTACGGCGGGTTTTGGCAAGCCGACCCCAATGATGGATCGGTCCTCGTTTTCCTGGCCCACAACATGGTTGACCTGGCGC
AGATGGCAAAGGGCATCGGGCTTGGTGTCTGGGCCGCGATTGAGGTGTTTCAACAGTCCGCAGCCGGCTCACCGGGCTGA

Upstream 100 bases:

>100_bases
GCTCACGCTTATCGCCCTTGGGCTGTCCATGTGGAGAGGCGGATTCGGCCGACATTTTACTTGATTATATAGCAAAATTA
TTTTATAATTTCAATATATT

Downstream 100 bases:

>100_bases
ATCGTCAGCTTTCGGCAGGCGTGCACAAATCAGAATCAGTTGAGTGGCTATGTCAGAAGGCCGGGGAGACACCGAGGGTG
CATCATCGGCCGAACGCCCA

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSETLQHIVESGQLAGAATLVWKNGTAQTTCFGWRDIERNLPVEQDTIFRIASMTKPITSVAALMLVDEGRIALNDPITR
YAPEFSQMRVLRSPGSPLDETDPAERLITFEDLLTHRAGLTYGDLHRSPIMQAYRGALGGDIDTDVAPDDWIAKLSQLPL
IHQPGEMWSYGRSTDLLGLLIARIEGEPLQAVLKRRIFDPLGMKDTSFLVPPEKRDRRAAAYGFDDEEKLIKRATWGGVV
VEERPVDMAYESGGQGLWSTVDDYLRFARLFLGDGSVDGVRLLRADTLARMMTNQLTEAQRASARLIGQKLFAAGRGFGL
GVSVVLEPDANDIMRRGGPGTVSWAGAYGGFWQADPNDGSVLVFLAHNMVDLAQMAKGIGLGVWAAIEVFQQSAAGSPG

Sequences:

>Translated_399_residues
MSETLQHIVESGQLAGAATLVWKNGTAQTTCFGWRDIERNLPVEQDTIFRIASMTKPITSVAALMLVDEGRIALNDPITR
YAPEFSQMRVLRSPGSPLDETDPAERLITFEDLLTHRAGLTYGDLHRSPIMQAYRGALGGDIDTDVAPDDWIAKLSQLPL
IHQPGEMWSYGRSTDLLGLLIARIEGEPLQAVLKRRIFDPLGMKDTSFLVPPEKRDRRAAAYGFDDEEKLIKRATWGGVV
VEERPVDMAYESGGQGLWSTVDDYLRFARLFLGDGSVDGVRLLRADTLARMMTNQLTEAQRASARLIGQKLFAAGRGFGL
GVSVVLEPDANDIMRRGGPGTVSWAGAYGGFWQADPNDGSVLVFLAHNMVDLAQMAKGIGLGVWAAIEVFQQSAAGSPG
>Mature_398_residues
SETLQHIVESGQLAGAATLVWKNGTAQTTCFGWRDIERNLPVEQDTIFRIASMTKPITSVAALMLVDEGRIALNDPITRY
APEFSQMRVLRSPGSPLDETDPAERLITFEDLLTHRAGLTYGDLHRSPIMQAYRGALGGDIDTDVAPDDWIAKLSQLPLI
HQPGEMWSYGRSTDLLGLLIARIEGEPLQAVLKRRIFDPLGMKDTSFLVPPEKRDRRAAAYGFDDEEKLIKRATWGGVVV
EERPVDMAYESGGQGLWSTVDDYLRFARLFLGDGSVDGVRLLRADTLARMMTNQLTEAQRASARLIGQKLFAAGRGFGLG
VSVVLEPDANDIMRRGGPGTVSWAGAYGGFWQADPNDGSVLVFLAHNMVDLAQMAKGIGLGVWAAIEVFQQSAAGSPG

Specific function: Binds Penicillin And Contributes To The Normal Morphology Of Escherichia Coli. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786574, Length=388, Percent_Identity=25.7731958762887, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082101, Length=274, Percent_Identity=25.5474452554745, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=297, Percent_Identity=24.5791245791246, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 43576; Mature: 43445

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLQHIVESGQLAGAATLVWKNGTAQTTCFGWRDIERNLPVEQDTIFRIASMTKPITS
CCHHHHHHHHCCCCCCEEEEEEECCCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHH
VAALMLVDEGRIALNDPITRYAPEFSQMRVLRSPGSPLDETDPAERLITFEDLLTHRAGL
HHHHHHCCCCCEEECCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
TYGDLHRSPIMQAYRGALGGDIDTDVAPDDWIAKLSQLPLIHQPGEMWSYGRSTDLLGLL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHCCCCCHHHHHHH
IARIEGEPLQAVLKRRIFDPLGMKDTSFLVPPEKRDRRAAAYGFDDEEKLIKRATWGGVV
HHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCCHHCCCHHHCCCCCHHHHHHHHCCCCEE
VEERPVDMAYESGGQGLWSTVDDYLRFARLFLGDGSVDGVRLLRADTLARMMTNQLTEAQ
EECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RASARLIGQKLFAAGRGFGLGVSVVLEPDANDIMRRGGPGTVSWAGAYGGFWQADPNDGS
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCC
VLVFLAHNMVDLAQMAKGIGLGVWAAIEVFQQSAAGSPG
EEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SETLQHIVESGQLAGAATLVWKNGTAQTTCFGWRDIERNLPVEQDTIFRIASMTKPITS
CHHHHHHHHCCCCCCEEEEEEECCCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHH
VAALMLVDEGRIALNDPITRYAPEFSQMRVLRSPGSPLDETDPAERLITFEDLLTHRAGL
HHHHHHCCCCCEEECCCHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
TYGDLHRSPIMQAYRGALGGDIDTDVAPDDWIAKLSQLPLIHQPGEMWSYGRSTDLLGLL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEECCCHHHCCCCCHHHHHHH
IARIEGEPLQAVLKRRIFDPLGMKDTSFLVPPEKRDRRAAAYGFDDEEKLIKRATWGGVV
HHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCCHHCCCHHHCCCCCHHHHHHHHCCCCEE
VEERPVDMAYESGGQGLWSTVDDYLRFARLFLGDGSVDGVRLLRADTLARMMTNQLTEAQ
EECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RASARLIGQKLFAAGRGFGLGVSVVLEPDANDIMRRGGPGTVSWAGAYGGFWQADPNDGS
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCC
VLVFLAHNMVDLAQMAKGIGLGVWAAIEVFQQSAAGSPG
EEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]