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The map label for this gene is livJ [C]

Identifier: 116625145

GI number: 116625145

Start: 7610780

End: 7612603

Strand: Direct

Name: livJ [C]

Synonym: Acid_6083

Alternate gene names: 116625145

Gene position: 7610780-7612603 (Clockwise)

Preceding gene: 116625144

Following gene: 116625147

Centisome position: 76.37

GC content: 62.99

Gene sequence:

>1824_bases
ATGCGCGACCTCGTCTTTGCCGTGGCGGCCCTGGCGCTGTGGTTCGGGGCCGCGCGCGCGCAGACTGTGCCCTGCCGGGT
CCCCGGCGCCAATGCCGTGGTGGCTCCGCCGCCCAGCCGCACGCTAGAACCGTACGCCAACACGCCCGAAGACCTGCGGC
CCTTTTCCAGATTTACCAAGCCGTATTACGAAAACTACACCAAATCTCCGGAGTACAACGGCACGGCGCGCGACCTGCCC
GAAGCCGACATCGCGAAGCTCGATGAGGTGGCGATCGCTTTTCTCGGTCCCATTGCGCAACACAAGGACGAGGCTCTGGG
GCAGGCCATGCTCCACGGCGCCGAGATGGCCGTCAAGGAAGCGAACGTGCGCGGCGGCTATTGCGGCAAACCCTTCGCCC
TGAAGGTTCACAACGATGCGGCAACCTGGGGCGCATCGAGCAACGAAATCGTCAGGATGGTCTACGACGAAAAGGTCTGG
GCCATGCTGGGTTCGATCAGCGGCGATTCGACGCACATCGCGCTGCGCGTTTCCCTGCGCGCCGAACTGCCGATCGTGAA
TAGCGCGTCCACCGATCCGACCATTCCTGAAACCATCATTCCGTGGAGTCTCACCGCAATCCAGGATGATCGCGTGCAAG
GCTACACCCTGGCGCGCCGCATCTATACAGACCTCGGGCTGAAACGTATCGCGCTCTTGCGCGTTAACGAACGCTACGGG
CGTTTCGGCGTCATCAAGTTCCGGGACGCGTCGCGCCGTCTTGGACATCCCGTGGTGATCGAACAGAAGTTCGCTCCGTC
CGACCAATCCTTCACGCGCCAGTTGGCGGTGATCAACGATTCACGGGTGGATGGCATTGTGCTGTGGGCCGATGCGGGCG
CCGCCGGGACCATCCTGAAACAGATGCACGAGATGGGCATGAAGCAACCCGTGTTCGGCAGTTTCCGTGTGGTGGGAGAC
GATCTCTTCCGCAACGCGGGAGCGTTCGCCGAAGGGCTCGAGGTGGTTTATCCGTTTGATCCGAACCGCGACCATGCGGT
GTGGACCGGTTTTCAGAAGCGTTTCGAGACCGCCTACCATGCCAAGGTGGACGCTTTTTCCGCGTTGGGCTTCGACACCA
TGAACGTCCTGCTGGGGGCAATCGGTCGGGCGGGCTTGAACCGCGGCCGCATTCGCGACGAGCTTTACGGTCTGGAGCGT
TACCCGGGCGTTACTGGGGAAATGATCTTCGACCCGAACGCCAAGAATAGTGCGCCGATGTACCTGGGCAAGGTCAAAGA
CGGCAAGTTGACCTACCGCCGGTACTCGATGGAGAAACCGTACGCGACGGTGGGCGAGAACGGAGTGCGCTACGCCGGGC
CGCCGCTCCCCGACGCCGTCAGGAAAGAGCCGAAGATCGGCATCTTCGGACCCGGGGCGGAAGCACAGGCCGCGAAACTG
GACGCACCCGGCCATAGGGTGGCTGGAATCAATTCCGATGTCCCATGGGGCAAGGCCTCTACGGAACTGGTCAAGATGGT
TTATGATCCGTCGGTGATCGGGCTTGTGGCGACGGACCGCCAGGCCGCGCACCTAGCCATGCAGCTCGCGGTCAAGAACT
TCGTGCCCGTGATCGCCGTCTCCGCGGACCGCACGCTGACCTCGACCAATGTTCCCTGGATCTTTCGCGTGTCGCCCGAA
ACCTCGCTCGCCGAGGCGGTTGGCTGCCTCACCGACGCCGCGCGCCAGGCCGGATGGAACCGGGGGCGGATTCGTGAACT
TCTGGCATCGGGGGCACGGGTCGGAGGCCGGTATGCGTTTGATGCGACTGGGGAGATGAAGTAA

Upstream 100 bases:

>100_bases
TGCCGGCGTCCACCGGTATCCAGGCGATTCTCTGCCGGCCAGAGTTGCTGGTGGAGATCGAAGCCATCGCCATGTTCACT
CCGGTTCAGGAGGATTGAGA

Downstream 100 bases:

>100_bases
GAATCCTCCGTTTACCATCTCCGCAACCCTCGGCGCCGGTCGATTCGCCGCCGCGGGCGGTCTCGAAGGCGCCGATAGCG
GTTCCACGCGGTCCGCCGTC

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: Branched-Chain Amino Acid Transporter; Branched Chain Amino Acid ABC Transporter; Twin-Arginine Translocation Pathway Signal; Amino Acid ABC Transporter Periplasmic Protein; ABC-Type Branched-Chain Amino Acid Transport System Protein; Branched-Chain Amino Acid ABC Transporter

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MRDLVFAVAALALWFGAARAQTVPCRVPGANAVVAPPPSRTLEPYANTPEDLRPFSRFTKPYYENYTKSPEYNGTARDLP
EADIAKLDEVAIAFLGPIAQHKDEALGQAMLHGAEMAVKEANVRGGYCGKPFALKVHNDAATWGASSNEIVRMVYDEKVW
AMLGSISGDSTHIALRVSLRAELPIVNSASTDPTIPETIIPWSLTAIQDDRVQGYTLARRIYTDLGLKRIALLRVNERYG
RFGVIKFRDASRRLGHPVVIEQKFAPSDQSFTRQLAVINDSRVDGIVLWADAGAAGTILKQMHEMGMKQPVFGSFRVVGD
DLFRNAGAFAEGLEVVYPFDPNRDHAVWTGFQKRFETAYHAKVDAFSALGFDTMNVLLGAIGRAGLNRGRIRDELYGLER
YPGVTGEMIFDPNAKNSAPMYLGKVKDGKLTYRRYSMEKPYATVGENGVRYAGPPLPDAVRKEPKIGIFGPGAEAQAAKL
DAPGHRVAGINSDVPWGKASTELVKMVYDPSVIGLVATDRQAAHLAMQLAVKNFVPVIAVSADRTLTSTNVPWIFRVSPE
TSLAEAVGCLTDAARQAGWNRGRIRELLASGARVGGRYAFDATGEMK

Sequences:

>Translated_607_residues
MRDLVFAVAALALWFGAARAQTVPCRVPGANAVVAPPPSRTLEPYANTPEDLRPFSRFTKPYYENYTKSPEYNGTARDLP
EADIAKLDEVAIAFLGPIAQHKDEALGQAMLHGAEMAVKEANVRGGYCGKPFALKVHNDAATWGASSNEIVRMVYDEKVW
AMLGSISGDSTHIALRVSLRAELPIVNSASTDPTIPETIIPWSLTAIQDDRVQGYTLARRIYTDLGLKRIALLRVNERYG
RFGVIKFRDASRRLGHPVVIEQKFAPSDQSFTRQLAVINDSRVDGIVLWADAGAAGTILKQMHEMGMKQPVFGSFRVVGD
DLFRNAGAFAEGLEVVYPFDPNRDHAVWTGFQKRFETAYHAKVDAFSALGFDTMNVLLGAIGRAGLNRGRIRDELYGLER
YPGVTGEMIFDPNAKNSAPMYLGKVKDGKLTYRRYSMEKPYATVGENGVRYAGPPLPDAVRKEPKIGIFGPGAEAQAAKL
DAPGHRVAGINSDVPWGKASTELVKMVYDPSVIGLVATDRQAAHLAMQLAVKNFVPVIAVSADRTLTSTNVPWIFRVSPE
TSLAEAVGCLTDAARQAGWNRGRIRELLASGARVGGRYAFDATGEMK
>Mature_607_residues
MRDLVFAVAALALWFGAARAQTVPCRVPGANAVVAPPPSRTLEPYANTPEDLRPFSRFTKPYYENYTKSPEYNGTARDLP
EADIAKLDEVAIAFLGPIAQHKDEALGQAMLHGAEMAVKEANVRGGYCGKPFALKVHNDAATWGASSNEIVRMVYDEKVW
AMLGSISGDSTHIALRVSLRAELPIVNSASTDPTIPETIIPWSLTAIQDDRVQGYTLARRIYTDLGLKRIALLRVNERYG
RFGVIKFRDASRRLGHPVVIEQKFAPSDQSFTRQLAVINDSRVDGIVLWADAGAAGTILKQMHEMGMKQPVFGSFRVVGD
DLFRNAGAFAEGLEVVYPFDPNRDHAVWTGFQKRFETAYHAKVDAFSALGFDTMNVLLGAIGRAGLNRGRIRDELYGLER
YPGVTGEMIFDPNAKNSAPMYLGKVKDGKLTYRRYSMEKPYATVGENGVRYAGPPLPDAVRKEPKIGIFGPGAEAQAAKL
DAPGHRVAGINSDVPWGKASTELVKMVYDPSVIGLVATDRQAAHLAMQLAVKNFVPVIAVSADRTLTSTNVPWIFRVSPE
TSLAEAVGCLTDAARQAGWNRGRIRELLASGARVGGRYAFDATGEMK

Specific function: This Protein Is A Component Of The Leucine, Isoleucine, Valine, (Threonine) Transport System, Which Is One Of The Two Periplasmic Binding Protein-Dependent Transport Systems Of The High-Affinity Transport Of The Branched-Chain Amino Acids. [C]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994941, Length=246, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 10140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 8822 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal med

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 66259; Mature: 66259

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLVFAVAALALWFGAARAQTVPCRVPGANAVVAPPPSRTLEPYANTPEDLRPFSRFTK
CHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCC
PYYENYTKSPEYNGTARDLPEADIAKLDEVAIAFLGPIAQHKDEALGQAMLHGAEMAVKE
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVRGGYCGKPFALKVHNDAATWGASSNEIVRMVYDEKVWAMLGSISGDSTHIALRVSLR
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEEEEEEE
AELPIVNSASTDPTIPETIIPWSLTAIQDDRVQGYTLARRIYTDLGLKRIALLRVNERYG
ECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEEECCCC
RFGVIKFRDASRRLGHPVVIEQKFAPSDQSFTRQLAVINDSRVDGIVLWADAGAAGTILK
CEEEEEEECCHHHCCCCEEEECCCCCCCHHHHHEEEEEECCCCCEEEEEECCCCHHHHHH
QMHEMGMKQPVFGSFRVVGDDLFRNAGAFAEGLEVVYPFDPNRDHAVWTGFQKRFETAYH
HHHHCCCCCCCCCCEEEECHHHHHCCCCHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHH
AKVDAFSALGFDTMNVLLGAIGRAGLNRGRIRDELYGLERYPGVTGEMIFDPNAKNSAPM
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCE
YLGKVKDGKLTYRRYSMEKPYATVGENGVRYAGPPLPDAVRKEPKIGIFGPGAEAQAAKL
EEEECCCCEEEEEEECCCCCCHHCCCCCCEECCCCCCHHHCCCCCEEEECCCCCCCCEEC
DAPGHRVAGINSDVPWGKASTELVKMVYDPSVIGLVATDRQAAHLAMQLAVKNFVPVIAV
CCCCCEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEE
SADRTLTSTNVPWIFRVSPETSLAEAVGCLTDAARQAGWNRGRIRELLASGARVGGRYAF
ECCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEE
DATGEMK
CCCCCCC
>Mature Secondary Structure
MRDLVFAVAALALWFGAARAQTVPCRVPGANAVVAPPPSRTLEPYANTPEDLRPFSRFTK
CHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCC
PYYENYTKSPEYNGTARDLPEADIAKLDEVAIAFLGPIAQHKDEALGQAMLHGAEMAVKE
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVRGGYCGKPFALKVHNDAATWGASSNEIVRMVYDEKVWAMLGSISGDSTHIALRVSLR
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEEEEEEE
AELPIVNSASTDPTIPETIIPWSLTAIQDDRVQGYTLARRIYTDLGLKRIALLRVNERYG
ECCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCHHEEEEEEEECCCC
RFGVIKFRDASRRLGHPVVIEQKFAPSDQSFTRQLAVINDSRVDGIVLWADAGAAGTILK
CEEEEEEECCHHHCCCCEEEECCCCCCCHHHHHEEEEEECCCCCEEEEEECCCCHHHHHH
QMHEMGMKQPVFGSFRVVGDDLFRNAGAFAEGLEVVYPFDPNRDHAVWTGFQKRFETAYH
HHHHCCCCCCCCCCEEEECHHHHHCCCCHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHH
AKVDAFSALGFDTMNVLLGAIGRAGLNRGRIRDELYGLERYPGVTGEMIFDPNAKNSAPM
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCCEEEECCCCCCCCCE
YLGKVKDGKLTYRRYSMEKPYATVGENGVRYAGPPLPDAVRKEPKIGIFGPGAEAQAAKL
EEEECCCCEEEEEEECCCCCCHHCCCCCCEECCCCCCHHHCCCCCEEEECCCCCCCCEEC
DAPGHRVAGINSDVPWGKASTELVKMVYDPSVIGLVATDRQAAHLAMQLAVKNFVPVIAV
CCCCCEEECCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEE
SADRTLTSTNVPWIFRVSPETSLAEAVGCLTDAARQAGWNRGRIRELLASGARVGGRYAF
ECCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEE
DATGEMK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA