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The map label for this gene is tldD [C]

Identifier: 116625043

GI number: 116625043

Start: 7491315

End: 7492880

Strand: Reverse

Name: tldD [C]

Synonym: Acid_5973

Alternate gene names: 116625043

Gene position: 7492880-7491315 (Counterclockwise)

Preceding gene: 116625045

Following gene: 116625042

Centisome position: 75.19

GC content: 62.32

Gene sequence:

>1566_bases
ATGCTGACACGCCGGAACTTCCTGGCGGCTTCTTCCGCCGCCGTGGCCAACCGTCTCTTCGCTGCTCCAAAGGATTCCAA
AACGCCCAACCCGGAGCTAGAAAAGCTGGGCGCGGTAGCCCTCGCCGAGGCGAAGAAGAATAAAGCCACTTACGCCGACA
TCCGCATCGTACGTATTAACGACCAGCGTCTCGGCATGCGCCTGTCTCCCGAGCGGGGCACGGGCAAGACCCTGGCTGTG
CCCAACGTCACGGAAGATTCCAGCTTCGGCTTCGGCGTGCGTGTCATAGTCAACGGCGCCTGGGGCTTCGCCTCTTCTCC
CATCGTCACACCCGAAGAGATTGCGCGCGTCACCGGCGAGGCCGTGATCATCGCCAAGGCAAACGCCACCATTCAGCCGA
AGCCTGTGAAACTGGCGCCCGTCAAAGCCTATCGGGACCGCTGGGAGACACCGCACGAACGTGACCCCTTCGCCGTGCCA
ATGGCCGAGAAGCTCGAACTGCTGCGCCGCGTCTCCGAAGAGGCCAAAAAAGGCGCCAAGGTTTTCAGCAGCACCGCCAC
TCTCAGTCTGCGTAGTGAGGATAAGTACTTCGCCTCCTCCGAAGGCTCTTCGATTCAGCAATTGATTCTTCAGATCTACG
GCAACGTGGATTCCACCGCCGTGGATCGCGAGAACAATATCTCGCGCACGCGCAACTACACGCCCACGCAGGCCTCCGCC
GGATGGGAATACGTGCCCGAAATGAACCTCGAAGAGAATGCGCAGCGGATCCGCGAAGAAGTGGTGGAGCATCTCACCGC
GCCGGCCGTGAAGCCTGGTAAGCGCGACCTGCTGCTGATGCCGAACCACCTCATGCTCACCATCCACGAGAGCGTCGCCC
ACCCCACCGAGCTCGATCGCGCCCTCGGCTACGAAGCCAACTACGCCGGCACCAGCTACATCACGCCCGATAAGATCGGC
AAGCGCATCGCCAGCGAGCACTGCACGTTCGTCGGCGATCGCATCTCACCGCGCGCTCTCGCCACCGTCGGCTACGACGA
TGAAGGGGTAAAGGCCACGCAGTGGACCATTATCGACCAGGGCATCTTCAAGAGCTACCAGACCACCCGCGAGCAGGCCG
CCTTCGTCGGCGAAAAGGAATCGCACGGATGCAGCCAGGCCGATAGCTGGGCCACCGTCCCCTTTCAGCGCATGCCCAAT
GTCTGGCTCAAAGCCGGTCCGCGCGAGACCACGCTCGAAAGCCTCATCGGCGGCATCGACGACGGCGTGCTCATCGATGG
CCGCGGCAGCTACTCCATCGATCAGCAGCGCTATAACATCCAGTTCGGCGGCGACGCCTTCTGGGAAATCAAGGGCGGCA
AGAAGCGCGGCATGATCTCGCGGGTCAGCTACCAATCACGCACGCCCGATTTCTGGCAGGCCTGCGACGGTACCGCCGGA
CCGGCCTACTGGCGCCAGTACGGCACCACCGGCGACGCCAAGGGCGAGCCCACGCAAATCAATTCCATCAGCCACGGCTG
CGCACCCACGCGCTTCCGCGGCATCAATGTGATTCTTACCGATTAA

Upstream 100 bases:

>100_bases
TACTGATACGAAAGCACATTGGGCCAAAAAATCACATGCACGCCTGGCCCCTTCGGAGCGTCACTCTGAAAGCCCGGCGG
CCTTCCGGTACAATACCTCA

Downstream 100 bases:

>100_bases
ACTCCCGAATGAATGCCGCCACGGTGAACCCCATGCTGACACGAGACGAAGCACAGAAACTTGCCCAGAAGGTCCTCGGG
CTCTCCACTTTTCCCGAATG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLTRRNFLAASSAAVANRLFAAPKDSKTPNPELEKLGAVALAEAKKNKATYADIRIVRINDQRLGMRLSPERGTGKTLAV
PNVTEDSSFGFGVRVIVNGAWGFASSPIVTPEEIARVTGEAVIIAKANATIQPKPVKLAPVKAYRDRWETPHERDPFAVP
MAEKLELLRRVSEEAKKGAKVFSSTATLSLRSEDKYFASSEGSSIQQLILQIYGNVDSTAVDRENNISRTRNYTPTQASA
GWEYVPEMNLEENAQRIREEVVEHLTAPAVKPGKRDLLLMPNHLMLTIHESVAHPTELDRALGYEANYAGTSYITPDKIG
KRIASEHCTFVGDRISPRALATVGYDDEGVKATQWTIIDQGIFKSYQTTREQAAFVGEKESHGCSQADSWATVPFQRMPN
VWLKAGPRETTLESLIGGIDDGVLIDGRGSYSIDQQRYNIQFGGDAFWEIKGGKKRGMISRVSYQSRTPDFWQACDGTAG
PAYWRQYGTTGDAKGEPTQINSISHGCAPTRFRGINVILTD

Sequences:

>Translated_521_residues
MLTRRNFLAASSAAVANRLFAAPKDSKTPNPELEKLGAVALAEAKKNKATYADIRIVRINDQRLGMRLSPERGTGKTLAV
PNVTEDSSFGFGVRVIVNGAWGFASSPIVTPEEIARVTGEAVIIAKANATIQPKPVKLAPVKAYRDRWETPHERDPFAVP
MAEKLELLRRVSEEAKKGAKVFSSTATLSLRSEDKYFASSEGSSIQQLILQIYGNVDSTAVDRENNISRTRNYTPTQASA
GWEYVPEMNLEENAQRIREEVVEHLTAPAVKPGKRDLLLMPNHLMLTIHESVAHPTELDRALGYEANYAGTSYITPDKIG
KRIASEHCTFVGDRISPRALATVGYDDEGVKATQWTIIDQGIFKSYQTTREQAAFVGEKESHGCSQADSWATVPFQRMPN
VWLKAGPRETTLESLIGGIDDGVLIDGRGSYSIDQQRYNIQFGGDAFWEIKGGKKRGMISRVSYQSRTPDFWQACDGTAG
PAYWRQYGTTGDAKGEPTQINSISHGCAPTRFRGINVILTD
>Mature_521_residues
MLTRRNFLAASSAAVANRLFAAPKDSKTPNPELEKLGAVALAEAKKNKATYADIRIVRINDQRLGMRLSPERGTGKTLAV
PNVTEDSSFGFGVRVIVNGAWGFASSPIVTPEEIARVTGEAVIIAKANATIQPKPVKLAPVKAYRDRWETPHERDPFAVP
MAEKLELLRRVSEEAKKGAKVFSSTATLSLRSEDKYFASSEGSSIQQLILQIYGNVDSTAVDRENNISRTRNYTPTQASA
GWEYVPEMNLEENAQRIREEVVEHLTAPAVKPGKRDLLLMPNHLMLTIHESVAHPTELDRALGYEANYAGTSYITPDKIG
KRIASEHCTFVGDRISPRALATVGYDDEGVKATQWTIIDQGIFKSYQTTREQAAFVGEKESHGCSQADSWATVPFQRMPN
VWLKAGPRETTLESLIGGIDDGVLIDGRGSYSIDQQRYNIQFGGDAFWEIKGGKKRGMISRVSYQSRTPDFWQACDGTAG
PAYWRQYGTTGDAKGEPTQINSISHGCAPTRFRGINVILTD

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=310, Percent_Identity=26.7741935483871, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 57372; Mature: 57372

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRRNFLAASSAAVANRLFAAPKDSKTPNPELEKLGAVALAEAKKNKATYADIRIVRIN
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
DQRLGMRLSPERGTGKTLAVPNVTEDSSFGFGVRVIVNGAWGFASSPIVTPEEIARVTGE
CCCCCCEECCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCC
AVIIAKANATIQPKPVKLAPVKAYRDRWETPHERDPFAVPMAEKLELLRRVSEEAKKGAK
EEEEEECCCEECCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VFSSTATLSLRSEDKYFASSEGSSIQQLILQIYGNVDSTAVDRENNISRTRNYTPTQASA
HHHCCEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC
GWEYVPEMNLEENAQRIREEVVEHLTAPAVKPGKRDLLLMPNHLMLTIHESVAHPTELDR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEHHHCCHHHHHH
ALGYEANYAGTSYITPDKIGKRIASEHCTFVGDRISPRALATVGYDDEGVKATQWTIIDQ
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEEEEEEECH
GIFKSYQTTREQAAFVGEKESHGCSQADSWATVPFQRMPNVWLKAGPRETTLESLIGGID
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHHHCCCC
DGVLIDGRGSYSIDQQRYNIQFGGDAFWEIKGGKKRGMISRVSYQSRTPDFWQACDGTAG
CCEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
PAYWRQYGTTGDAKGEPTQINSISHGCAPTRFRGINVILTD
HHHHHHCCCCCCCCCCCCEECCCCCCCCCCEECCEEEEEEC
>Mature Secondary Structure
MLTRRNFLAASSAAVANRLFAAPKDSKTPNPELEKLGAVALAEAKKNKATYADIRIVRIN
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
DQRLGMRLSPERGTGKTLAVPNVTEDSSFGFGVRVIVNGAWGFASSPIVTPEEIARVTGE
CCCCCCEECCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCC
AVIIAKANATIQPKPVKLAPVKAYRDRWETPHERDPFAVPMAEKLELLRRVSEEAKKGAK
EEEEEECCCEECCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VFSSTATLSLRSEDKYFASSEGSSIQQLILQIYGNVDSTAVDRENNISRTRNYTPTQASA
HHHCCEEEEEECCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC
GWEYVPEMNLEENAQRIREEVVEHLTAPAVKPGKRDLLLMPNHLMLTIHESVAHPTELDR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEHHHCCHHHHHH
ALGYEANYAGTSYITPDKIGKRIASEHCTFVGDRISPRALATVGYDDEGVKATQWTIIDQ
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEECCCCCCCEEEEEEEECH
GIFKSYQTTREQAAFVGEKESHGCSQADSWATVPFQRMPNVWLKAGPRETTLESLIGGID
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHHHCCCC
DGVLIDGRGSYSIDQQRYNIQFGGDAFWEIKGGKKRGMISRVSYQSRTPDFWQACDGTAG
CCEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
PAYWRQYGTTGDAKGEPTQINSISHGCAPTRFRGINVILTD
HHHHHHCCCCCCCCCCCCEECCCCCCCCCCEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]