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The map label for this gene is pmbA [C]

Identifier: 116625042

GI number: 116625042

Start: 7489906

End: 7491306

Strand: Reverse

Name: pmbA [C]

Synonym: Acid_5972

Alternate gene names: 116625042

Gene position: 7491306-7489906 (Counterclockwise)

Preceding gene: 116625043

Following gene: 116625041

Centisome position: 75.17

GC content: 63.67

Gene sequence:

>1401_bases
ATGAATGCCGCCACGGTGAACCCCATGCTGACACGAGACGAAGCACAGAAACTTGCCCAGAAGGTCCTCGGGCTCTCCAC
TTTTCCCGAATGCCAGGTGACGATTTCCGCCAGCGAGCAGGCGTACACGCGGTTTGCCAATAACGGCATCACCACGGCCT
CGCTAAACCTGCGCCATACCGTCTCCATCGCGGTCTCGCGCGATGGCAAGGCGGGTGTGATGACCGTGAACGATCTCGAC
GACGCATCGCTGCGCGCCGCCGTAAAGAAGGCCGAGGAACTCGCCGCCATCGCGCCGGCCAATCCGGAGCGGCTGAAGCC
ACTCGGCCCTCAGCCATATCCCACGGTCAACGATTTCGACGAGCGCACCGCCTCCGCGCGTTCGCCCGAGATGATTCCGC
ACGTGAAGACCATCATCGATCTCGCGGTCAAGCAGAAGCAGGTTGCCGCGGGACTGATCGAGCGCTCGCATCACGTCAAC
GCGATCGCCAACAAGGCCGGGCTCTTCGGCTATCACAACTCGGCCGATTCGCAGCTCACCACCACCATCCGCATGGCCGA
TGGCTCCAGCTCCGGATGGGCCGGCCAGCCCTCCACCCGCCTCTCCGACATCGATAGCGCGAAGCTCGGCGCCACTGCCA
GCGAGAAGTGCGCGCGCTGGAAGAATCCCCAGAAGATCGAGCCCGGCAATTACACCGTGGTGCTCGAGCCAACCGCCGCC
GCCGATATCGTACGCCTCATGGCCGGCGCCTTCAGCGCGCGCAACACCGAGGAGGGCCGCACCTTTCTCAGCAAGCGCGG
CGGCGGCAGTCTGCTCGGCGAAAAGGTCTTTCCGGATTTCGTAACTCTGCGCAGCGATCCCTTCGATCCGCGCCAGCCCT
CTTCGCCGTGGACCGGCGACCTGCTGCCCACCCGCGCGATTACGTGGGTCGATAAAGGCGTGATCGCCAACCTGGCCTAC
GATCGCTATTGGGCGGAGAAGACCGGCAAGCAGCCCACGCCAGGAGGTGGCGGCGGCGGGCGCGGTGGTGGTGGTGGTGG
ATTTGGCGGCGGCGCGCAAACCAGTCTGATTCTCGAAGGCGGTAACAAGACCCTGGAGCAGCTAATCGCCGGCGTGGAGC
GAGGCCTGCTGGTCACGCACTTCTGGTACATCCGCTTCGTGAACCAGCAGACCTTGCAGCACACCGGGCTCACGCGCGAC
GGACTTTTCCTGATCGAGAACGGCAAAATCACTACTCCTGTGATGAACTTCCGCTTCCTCGAAAGTCCCGTGCGACTGCT
CAAGAATACGAAGCAGCTCGGTCAGGCCGTGCGCGTCCGCGGCCTCGAAGGCGGCATGATGATCTCTCCCGCCCTGGTCG
CTACCGATTTTCCGCTGCCCTCGATTTCCGACGCGATTTAG

Upstream 100 bases:

>100_bases
ACGCCAAGGGCGAGCCCACGCAAATCAATTCCATCAGCCACGGCTGCGCACCCACGCGCTTCCGCGGCATCAATGTGATT
CTTACCGATTAAACTCCCGA

Downstream 100 bases:

>100_bases
GGTCCCGGCACACACTGGCCACGCATGTGCCCTCCGTCACTGCGGAGAACGAAGCATGAAAAAACTAATGGTTTCCGCAG
CCGCCCTTTCGGTGGCATTG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: TldD/PmbA Family Protein; PmbA Protein; Zinc-Dependent Protease TldD/PmbA Family; CalR5 Protein; TldD Protein; Zinc-Dependent Protease; Modulator Of DNA Gyrase; Zn-Dependent Protease; TldE-Like Protein; LOW QUALITY PROTEIN CalR5 Protein; Protein PmbA; DNA Gyrase Modulator Family Protein; TldD/PmbA Family; Modulator Of DNA Gyrase Protein TldD; Zinc Protease PmbA; Microcin-Processing Peptidase PmbA; Zn-Dependent Protease-Like Protein

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MNAATVNPMLTRDEAQKLAQKVLGLSTFPECQVTISASEQAYTRFANNGITTASLNLRHTVSIAVSRDGKAGVMTVNDLD
DASLRAAVKKAEELAAIAPANPERLKPLGPQPYPTVNDFDERTASARSPEMIPHVKTIIDLAVKQKQVAAGLIERSHHVN
AIANKAGLFGYHNSADSQLTTTIRMADGSSSGWAGQPSTRLSDIDSAKLGATASEKCARWKNPQKIEPGNYTVVLEPTAA
ADIVRLMAGAFSARNTEEGRTFLSKRGGGSLLGEKVFPDFVTLRSDPFDPRQPSSPWTGDLLPTRAITWVDKGVIANLAY
DRYWAEKTGKQPTPGGGGGGRGGGGGGFGGGAQTSLILEGGNKTLEQLIAGVERGLLVTHFWYIRFVNQQTLQHTGLTRD
GLFLIENGKITTPVMNFRFLESPVRLLKNTKQLGQAVRVRGLEGGMMISPALVATDFPLPSISDAI

Sequences:

>Translated_466_residues
MNAATVNPMLTRDEAQKLAQKVLGLSTFPECQVTISASEQAYTRFANNGITTASLNLRHTVSIAVSRDGKAGVMTVNDLD
DASLRAAVKKAEELAAIAPANPERLKPLGPQPYPTVNDFDERTASARSPEMIPHVKTIIDLAVKQKQVAAGLIERSHHVN
AIANKAGLFGYHNSADSQLTTTIRMADGSSSGWAGQPSTRLSDIDSAKLGATASEKCARWKNPQKIEPGNYTVVLEPTAA
ADIVRLMAGAFSARNTEEGRTFLSKRGGGSLLGEKVFPDFVTLRSDPFDPRQPSSPWTGDLLPTRAITWVDKGVIANLAY
DRYWAEKTGKQPTPGGGGGGRGGGGGGFGGGAQTSLILEGGNKTLEQLIAGVERGLLVTHFWYIRFVNQQTLQHTGLTRD
GLFLIENGKITTPVMNFRFLESPVRLLKNTKQLGQAVRVRGLEGGMMISPALVATDFPLPSISDAI
>Mature_466_residues
MNAATVNPMLTRDEAQKLAQKVLGLSTFPECQVTISASEQAYTRFANNGITTASLNLRHTVSIAVSRDGKAGVMTVNDLD
DASLRAAVKKAEELAAIAPANPERLKPLGPQPYPTVNDFDERTASARSPEMIPHVKTIIDLAVKQKQVAAGLIERSHHVN
AIANKAGLFGYHNSADSQLTTTIRMADGSSSGWAGQPSTRLSDIDSAKLGATASEKCARWKNPQKIEPGNYTVVLEPTAA
ADIVRLMAGAFSARNTEEGRTFLSKRGGGSLLGEKVFPDFVTLRSDPFDPRQPSSPWTGDLLPTRAITWVDKGVIANLAY
DRYWAEKTGKQPTPGGGGGGRGGGGGGFGGGAQTSLILEGGNKTLEQLIAGVERGLLVTHFWYIRFVNQQTLQHTGLTRD
GLFLIENGKITTPVMNFRFLESPVRLLKNTKQLGQAVRVRGLEGGMMISPALVATDFPLPSISDAI

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49831; Mature: 49831

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAATVNPMLTRDEAQKLAQKVLGLSTFPECQVTISASEQAYTRFANNGITTASLNLRHT
CCCCCCCCHHCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEEEEEE
VSIAVSRDGKAGVMTVNDLDDASLRAAVKKAEELAAIAPANPERLKPLGPQPYPTVNDFD
EEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHH
ERTASARSPEMIPHVKTIIDLAVKQKQVAAGLIERSHHVNAIANKAGLFGYHNSADSQLT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEE
TTIRMADGSSSGWAGQPSTRLSDIDSAKLGATASEKCARWKNPQKIEPGNYTVVLEPTAA
EEEEEECCCCCCCCCCCCCCHHCCCCHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHH
ADIVRLMAGAFSARNTEEGRTFLSKRGGGSLLGEKVFPDFVTLRSDPFDPRQPSSPWTGD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCHHEECCCCCCCCCCCCCCCCC
LLPTRAITWVDKGVIANLAYDRYWAEKTGKQPTPGGGGGGRGGGGGGFGGGAQTSLILEG
CCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
GNKTLEQLIAGVERGLLVTHFWYIRFVNQQTLQHTGLTRDGLFLIENGKITTPVMNFRFL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCHHHHHHH
ESPVRLLKNTKQLGQAVRVRGLEGGMMISPALVATDFPLPSISDAI
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHEEECCCCCCHHCCC
>Mature Secondary Structure
MNAATVNPMLTRDEAQKLAQKVLGLSTFPECQVTISASEQAYTRFANNGITTASLNLRHT
CCCCCCCCHHCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEEEEEE
VSIAVSRDGKAGVMTVNDLDDASLRAAVKKAEELAAIAPANPERLKPLGPQPYPTVNDFD
EEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCHH
ERTASARSPEMIPHVKTIIDLAVKQKQVAAGLIERSHHVNAIANKAGLFGYHNSADSQLT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEE
TTIRMADGSSSGWAGQPSTRLSDIDSAKLGATASEKCARWKNPQKIEPGNYTVVLEPTAA
EEEEEECCCCCCCCCCCCCCHHCCCCHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHH
ADIVRLMAGAFSARNTEEGRTFLSKRGGGSLLGEKVFPDFVTLRSDPFDPRQPSSPWTGD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCHHEECCCCCCCCCCCCCCCCC
LLPTRAITWVDKGVIANLAYDRYWAEKTGKQPTPGGGGGGRGGGGGGFGGGAQTSLILEG
CCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
GNKTLEQLIAGVERGLLVTHFWYIRFVNQQTLQHTGLTRDGLFLIENGKITTPVMNFRFL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCHHHHHHH
ESPVRLLKNTKQLGQAVRVRGLEGGMMISPALVATDFPLPSISDAI
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA