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The map label for this gene is 116624826

Identifier: 116624826

GI number: 116624826

Start: 7203638

End: 7205362

Strand: Reverse

Name: 116624826

Synonym: Acid_5750

Alternate gene names: NA

Gene position: 7205362-7203638 (Counterclockwise)

Preceding gene: 116624827

Following gene: 116624824

Centisome position: 72.3

GC content: 63.36

Gene sequence:

>1725_bases
ATGAAGAGGCTTCCGCGGGCGGACGTGGCCATTGTCGGCGGAGGCTGGTCAGGGCTCCTGATGGCCAAGGAACTGGGCGC
GCGCACAGGGTTGAGTGTGGTGGTGCTGGAACGCGGAGCGCCGCGCAAAAGCACCGATTATTTCGAAGGAATGGACGAGC
TGGATTACGCGATCCGCCTGCGCATGATGCAGGACGCGTCGAAAGAGACGGTGACGTTCCGGCACACCTCGAAGGATAAG
GCGCTCCCGATCCGGCAGTTCGCGAATTTCCTGCCGGGCACGGGGGTAGGCGGCGCGGGAGAGCATTGGAACGGGATCAC
GCCGCGGTTTTTGCCGGACTGCTTCGAGCTTTTAACGCGCACCGTGGAACGCTACGGCGCGGGGAAGCTGCCCGCGAATC
ATGCGCTGCAGGACTGGGGGATCACGTACGCGGAGCTGGAACCTTTTTATACGCGCGCGGAGAGGCTCCTCGGGATTTCG
GGACAGAGGGGACTCGATCCGTTCGAGGGGCCGCATTCGGCGGAGTATCCGACGCCTCCCCAGAAGACGCCATACTTTCC
GTCGCTGTTCCGCGAGGCGGCGCGGTCACTCGGGTATCATCCGTTTCCGGCGCCATCCGCCAATCTGAGCCAGGCTTACC
GAACTCCTGATGGAATCGTGCGGCCGGCGTGCGAATACTGCGGGTTTTGCGAGCGCTACGGGTGCATGGTGGGCGCGAAG
GCGCAGCCGACCAACACGCTGCTGCCGGTGATCGCGCGGCAGAAAAGCGTGACAGTGCGGACGGGCGCGAACGTGCGGCG
GGTGCTTTATAAGGATGGCAAGGCGACCGGCGTATCGTATGTGGACGCGAACGGCGAAGAGACGGAGCAGCCGGCCGACC
TGGTGGTGCTGGCTTCCTGGACGTTGAACAACACGCGGCTGCTGATGCTATCCAGGATTGGGGATGCGTACGATGCGGCC
AGCGGCAAGGGCCAGGTGGGGCGCAATCTGACGCACCAGGCGGTTTCGCGGGGAGTGGTGCTGTTCTTCGACCGGCCGTT
GAACCGGTTCATGGGCTCCGGAGCATGCGGCATCGTGATTCGGGACCTGGACGGCGACAATTTCGATCACGGGCCGTTGA
ATTTCCTGCGCGGGGCCTATGCCGCAGCCTTCGCCCGCGGGAACCCCCCGATTGGCGCCTTCGGAGTGGTGCCGTCCTCG
GTAAAGGGCACGTGGGGCTCGGAATGGAAAAAGGCGGCGATCGATGCGTTCGATTGCACGGCGAGTTTTGGAATCTCCGG
CGAGCATCTTGCCTATCGCTCGAATTACATGGACCTGGATCCGACTTACCGGGATTCGAATGGCGACCCGCTGTTGCGCA
TGACCATGGACTGGAACGACAATGAGCGCAACATCATCGACTTTGTGTCGGCGAAGATGGCGCAAGTGGGGCGTGCGATG
GGAGCGCGGGAGGTTTTGGCGCCGCCGCTGCCGCGACGCTACGATGTGAACACTTACCGCTCCACGCATCTGCAGGGCGG
TACGATTATGGGCGCAAACCCTGCGAACTCGGTGGTAAATCCGTGGCTGCAGCACTGGCAGGTGCCGAACCTTTTCGTGC
TGGGCGCTTCGACGTTTCCGCAGAACCCGTCGGGGAATCCGACGCTGACGATTCTGGCGCAGACACTGCGCACGGCGGAC
GCGGTGATCGACCGGTATTTGAAGCGGCCCGGGGTTCTTGCGTGA

Upstream 100 bases:

>100_bases
GCGAGCACGTGGACCAGCATTATGGGAAGGCGTATCGTCCCAAGCAGCGCAGCCTCGTGGATGTGGTGGGGCATCCGGTG
AAGCCGTCGGAGGACGCGGA

Downstream 100 bases:

>100_bases
TCAGTGCTTCAGCAACTCGGTCCAGTTGACGATCACGGTGATGGGGGTGGGAACTGAGCTGGCCCTGTCGATGCTGCTGA
CCAGAAAGCGCTTGCCATCC

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MKRLPRADVAIVGGGWSGLLMAKELGARTGLSVVVLERGAPRKSTDYFEGMDELDYAIRLRMMQDASKETVTFRHTSKDK
ALPIRQFANFLPGTGVGGAGEHWNGITPRFLPDCFELLTRTVERYGAGKLPANHALQDWGITYAELEPFYTRAERLLGIS
GQRGLDPFEGPHSAEYPTPPQKTPYFPSLFREAARSLGYHPFPAPSANLSQAYRTPDGIVRPACEYCGFCERYGCMVGAK
AQPTNTLLPVIARQKSVTVRTGANVRRVLYKDGKATGVSYVDANGEETEQPADLVVLASWTLNNTRLLMLSRIGDAYDAA
SGKGQVGRNLTHQAVSRGVVLFFDRPLNRFMGSGACGIVIRDLDGDNFDHGPLNFLRGAYAAAFARGNPPIGAFGVVPSS
VKGTWGSEWKKAAIDAFDCTASFGISGEHLAYRSNYMDLDPTYRDSNGDPLLRMTMDWNDNERNIIDFVSAKMAQVGRAM
GAREVLAPPLPRRYDVNTYRSTHLQGGTIMGANPANSVVNPWLQHWQVPNLFVLGASTFPQNPSGNPTLTILAQTLRTAD
AVIDRYLKRPGVLA

Sequences:

>Translated_574_residues
MKRLPRADVAIVGGGWSGLLMAKELGARTGLSVVVLERGAPRKSTDYFEGMDELDYAIRLRMMQDASKETVTFRHTSKDK
ALPIRQFANFLPGTGVGGAGEHWNGITPRFLPDCFELLTRTVERYGAGKLPANHALQDWGITYAELEPFYTRAERLLGIS
GQRGLDPFEGPHSAEYPTPPQKTPYFPSLFREAARSLGYHPFPAPSANLSQAYRTPDGIVRPACEYCGFCERYGCMVGAK
AQPTNTLLPVIARQKSVTVRTGANVRRVLYKDGKATGVSYVDANGEETEQPADLVVLASWTLNNTRLLMLSRIGDAYDAA
SGKGQVGRNLTHQAVSRGVVLFFDRPLNRFMGSGACGIVIRDLDGDNFDHGPLNFLRGAYAAAFARGNPPIGAFGVVPSS
VKGTWGSEWKKAAIDAFDCTASFGISGEHLAYRSNYMDLDPTYRDSNGDPLLRMTMDWNDNERNIIDFVSAKMAQVGRAM
GAREVLAPPLPRRYDVNTYRSTHLQGGTIMGANPANSVVNPWLQHWQVPNLFVLGASTFPQNPSGNPTLTILAQTLRTAD
AVIDRYLKRPGVLA
>Mature_574_residues
MKRLPRADVAIVGGGWSGLLMAKELGARTGLSVVVLERGAPRKSTDYFEGMDELDYAIRLRMMQDASKETVTFRHTSKDK
ALPIRQFANFLPGTGVGGAGEHWNGITPRFLPDCFELLTRTVERYGAGKLPANHALQDWGITYAELEPFYTRAERLLGIS
GQRGLDPFEGPHSAEYPTPPQKTPYFPSLFREAARSLGYHPFPAPSANLSQAYRTPDGIVRPACEYCGFCERYGCMVGAK
AQPTNTLLPVIARQKSVTVRTGANVRRVLYKDGKATGVSYVDANGEETEQPADLVVLASWTLNNTRLLMLSRIGDAYDAA
SGKGQVGRNLTHQAVSRGVVLFFDRPLNRFMGSGACGIVIRDLDGDNFDHGPLNFLRGAYAAAFARGNPPIGAFGVVPSS
VKGTWGSEWKKAAIDAFDCTASFGISGEHLAYRSNYMDLDPTYRDSNGDPLLRMTMDWNDNERNIIDFVSAKMAQVGRAM
GAREVLAPPLPRRYDVNTYRSTHLQGGTIMGANPANSVVNPWLQHWQVPNLFVLGASTFPQNPSGNPTLTILAQTLRTAD
AVIDRYLKRPGVLA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 62829; Mature: 62829

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLPRADVAIVGGGWSGLLMAKELGARTGLSVVVLERGAPRKSTDYFEGMDELDYAIRL
CCCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHH
RMMQDASKETVTFRHTSKDKALPIRQFANFLPGTGVGGAGEHWNGITPRFLPDCFELLTR
HHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TVERYGAGKLPANHALQDWGITYAELEPFYTRAERLLGISGQRGLDPFEGPHSAEYPTPP
HHHHHCCCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
QKTPYFPSLFREAARSLGYHPFPAPSANLSQAYRTPDGIVRPACEYCGFCERYGCMVGAK
CCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCHHHHHCCEECCC
AQPTNTLLPVIARQKSVTVRTGANVRRVLYKDGKATGVSYVDANGEETEQPADLVVLASW
CCCCCCHHHHHHCCCEEEEECCCCEEEHEEECCCCCCEEEEECCCCCCCCCCCEEEEEEE
TLNNTRLLMLSRIGDAYDAASGKGQVGRNLTHQAVSRGVVLFFDRPLNRFMGSGACGIVI
ECCCCEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHCCEEEEECCCHHHHHCCCCEEEEE
RDLDGDNFDHGPLNFLRGAYAAAFARGNPPIGAFGVVPSSVKGTWGSEWKKAAIDAFDCT
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCH
ASFGISGEHLAYRSNYMDLDPTYRDSNGDPLLRMTMDWNDNERNIIDFVSAKMAQVGRAM
HHCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GAREVLAPPLPRRYDVNTYRSTHLQGGTIMGANPANSVVNPWLQHWQVPNLFVLGASTFP
CCHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCC
QNPSGNPTLTILAQTLRTADAVIDRYLKRPGVLA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKRLPRADVAIVGGGWSGLLMAKELGARTGLSVVVLERGAPRKSTDYFEGMDELDYAIRL
CCCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHH
RMMQDASKETVTFRHTSKDKALPIRQFANFLPGTGVGGAGEHWNGITPRFLPDCFELLTR
HHHHCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TVERYGAGKLPANHALQDWGITYAELEPFYTRAERLLGISGQRGLDPFEGPHSAEYPTPP
HHHHHCCCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
QKTPYFPSLFREAARSLGYHPFPAPSANLSQAYRTPDGIVRPACEYCGFCERYGCMVGAK
CCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCHHHHHCCEECCC
AQPTNTLLPVIARQKSVTVRTGANVRRVLYKDGKATGVSYVDANGEETEQPADLVVLASW
CCCCCCHHHHHHCCCEEEEECCCCEEEHEEECCCCCCEEEEECCCCCCCCCCCEEEEEEE
TLNNTRLLMLSRIGDAYDAASGKGQVGRNLTHQAVSRGVVLFFDRPLNRFMGSGACGIVI
ECCCCEEEEEECCCCHHHCCCCCCCCCCCHHHHHHHCCEEEEECCCHHHHHCCCCEEEEE
RDLDGDNFDHGPLNFLRGAYAAAFARGNPPIGAFGVVPSSVKGTWGSEWKKAAIDAFDCT
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCH
ASFGISGEHLAYRSNYMDLDPTYRDSNGDPLLRMTMDWNDNERNIIDFVSAKMAQVGRAM
HHCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GAREVLAPPLPRRYDVNTYRSTHLQGGTIMGANPANSVVNPWLQHWQVPNLFVLGASTFP
CCHHHHCCCCCCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCC
QNPSGNPTLTILAQTLRTADAVIDRYLKRPGVLA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]