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The map label for this gene is plsC [H]

Identifier: 116624735

GI number: 116624735

Start: 7093036

End: 7093773

Strand: Reverse

Name: plsC [H]

Synonym: Acid_5659

Alternate gene names: 116624735

Gene position: 7093773-7093036 (Counterclockwise)

Preceding gene: 116624736

Following gene: 116624734

Centisome position: 71.18

GC content: 61.92

Gene sequence:

>738_bases
ATGAGTCTTGTCCGGTCCCTGCTTTTCTCTACTCCTCTTATTGTCCTTTGCACGATCGTGATGGGCACCCTCTCCCTGAT
CGCGTCCTTCTTCGATTCCAGCGGCAACTCGCAGCACGCCATCGCCCGCGTATGGGCGCGAATGCTGCTTGCCGTCAGCT
TCATGCGCGTCCGCGTCGAAGGGCTGGGGAAGCTCGACCGCAAAGGCGCCTACGTTTTCGTGGCCAATCACGGCAGCTTC
ATGGATATCCCGGCGCTGCTTGCCGCTCTGCCGCAGGAATTTCGCTTCTTCGCCAAGAAGGGCCTCTTCAAGATTCCGTT
TCTCGGTACGCACCTGCGACGAGCCGGACATCTTCCGGTGGATCGCTCCAGCCCGCGCGCTTCGCTCAAGAGCATGATGG
AGGCCGCGCGGATCATCAGCAATCGCGGCATCTCCGTGCTCAATTTCCCCGAGGGCGGACGCTCCGCCGAAGGCCTGCGC
GAGTTCAAGGAAGGTCCCGCGTATATCGCGATCAAAGCCGGAGTGCCGGTTGTCCCGGTCGCGTTGATCGGCCTCCGCGA
GCTGCTCCCCATGGGGTCGATTCACCTCAAGAGCGGCAAGGTGCTCATCCGCGTCGGCGATCCGATATCCACCAAGGATC
TCCAGGCCTCGGACCGCCTGGAGCTCACGCACCGCCTCTACCGCGAGATTTCCACGCTGCTTTACAAAGAGCCGCGACCG
CGAGGGAGCGATTGGTAA

Upstream 100 bases:

>100_bases
CTCTGCGATGCCGCATCCAACGACGCCGTCTTCATCACCGGCTCGCTCTTTCTTGTCGCCGAGGCGCGAGCTCTACTGCT
GGTATGATTGGTGCGAAACG

Downstream 100 bases:

>100_bases
TTCAGATTTGCGGACGCTCCCTGACGGTCGCGGCTCTGATTGGTCGCGGACAAAATGGGCGCGTATCGACAGGCGCGAAG
CTTGATCTTCAGACGAGCGA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSLVRSLLFSTPLIVLCTIVMGTLSLIASFFDSSGNSQHAIARVWARMLLAVSFMRVRVEGLGKLDRKGAYVFVANHGSF
MDIPALLAALPQEFRFFAKKGLFKIPFLGTHLRRAGHLPVDRSSPRASLKSMMEAARIISNRGISVLNFPEGGRSAEGLR
EFKEGPAYIAIKAGVPVVPVALIGLRELLPMGSIHLKSGKVLIRVGDPISTKDLQASDRLELTHRLYREISTLLYKEPRP
RGSDW

Sequences:

>Translated_245_residues
MSLVRSLLFSTPLIVLCTIVMGTLSLIASFFDSSGNSQHAIARVWARMLLAVSFMRVRVEGLGKLDRKGAYVFVANHGSF
MDIPALLAALPQEFRFFAKKGLFKIPFLGTHLRRAGHLPVDRSSPRASLKSMMEAARIISNRGISVLNFPEGGRSAEGLR
EFKEGPAYIAIKAGVPVVPVALIGLRELLPMGSIHLKSGKVLIRVGDPISTKDLQASDRLELTHRLYREISTLLYKEPRP
RGSDW
>Mature_244_residues
SLVRSLLFSTPLIVLCTIVMGTLSLIASFFDSSGNSQHAIARVWARMLLAVSFMRVRVEGLGKLDRKGAYVFVANHGSFM
DIPALLAALPQEFRFFAKKGLFKIPFLGTHLRRAGHLPVDRSSPRASLKSMMEAARIISNRGISVLNFPEGGRSAEGLRE
FKEGPAYIAIKAGVPVVPVALIGLRELLPMGSIHLKSGKVLIRVGDPISTKDLQASDRLELTHRLYREISTLLYKEPRPR
GSDW

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=196, Percent_Identity=29.5918367346939, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI15100175, Length=196, Percent_Identity=29.5918367346939, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI6041665, Length=193, Percent_Identity=26.9430051813472, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789395, Length=155, Percent_Identity=29.6774193548387, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=181, Percent_Identity=30.939226519337, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=235, Percent_Identity=27.2340425531915, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281364648, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582856, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582854, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27022; Mature: 26891

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVRSLLFSTPLIVLCTIVMGTLSLIASFFDSSGNSQHAIARVWARMLLAVSFMRVRVE
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGKLDRKGAYVFVANHGSFMDIPALLAALPQEFRFFAKKGLFKIPFLGTHLRRAGHLPV
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHCCCCCC
DRSSPRASLKSMMEAARIISNRGISVLNFPEGGRSAEGLREFKEGPAYIAIKAGVPVVPV
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCHHHH
ALIGLRELLPMGSIHLKSGKVLIRVGDPISTKDLQASDRLELTHRLYREISTLLYKEPRP
HHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
RGSDW
CCCCC
>Mature Secondary Structure 
SLVRSLLFSTPLIVLCTIVMGTLSLIASFFDSSGNSQHAIARVWARMLLAVSFMRVRVE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGKLDRKGAYVFVANHGSFMDIPALLAALPQEFRFFAKKGLFKIPFLGTHLRRAGHLPV
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHCCCCCC
DRSSPRASLKSMMEAARIISNRGISVLNFPEGGRSAEGLREFKEGPAYIAIKAGVPVVPV
CCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCHHHH
ALIGLRELLPMGSIHLKSGKVLIRVGDPISTKDLQASDRLELTHRLYREISTLLYKEPRP
HHHHHHHHCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
RGSDW
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]