Click here to switch to the map view.

The map label for this gene is dnrK [H]

Identifier: 116624730

GI number: 116624730

Start: 7086580

End: 7087557

Strand: Direct

Name: dnrK [H]

Synonym: Acid_5654

Alternate gene names: 116624730

Gene position: 7086580-7087557 (Clockwise)

Preceding gene: 116624725

Following gene: 116624732

Centisome position: 71.11

GC content: 70.25

Gene sequence:

>978_bases
ATGGAATGGTGGCAATTGAGCGATTTGTGTACGCCGTGGTGCGTTCACGTGGCGGCGACCCTGCGGGTTCCGGAGCACAT
CGCGGCAGGCCATGGGGAGATCGGGCAGTTGGCCGCCGCGGCGGCAGCGGACCGGGATTCGCTGGAAAGGGTGCTGCGGC
ACCTGGTGAGCAAGGGGTTATTCGCGGAGCCTTCGCCGGGAGTCTTCGCGCTGAACGAAGCCGCGCGGCCATTGCTGGAG
GAAGGGGCGCGGATCGGCTTGGATCTGGACGGTTTCGGCGGCCGGATGGCCCACGCATGGGGGACGCTGCTCTCGGCTGT
ACGCACCGGGCGTCCGGCGTATCACGAGGCGTTCGGGAGGCCGTACTGGGAGGACCTGGAGGCGAATCCACCGATCGCGG
CGTCATTCGATGCCTTGATGGGAGTAGCGGGGCACGGTGTACCGGACCCGAACGTGCTGCCGGATCCGGCGGACTGGGAG
AAGGTGCGCATGGTGGTGGATGTCGGCGGCGGCGCCGGGGACTTGTTAGCGGCGGTGCTGCGGGCGCATCCCGGGACGCG
GGGCACGCTGGTCGATCTGCCGCGGACCGTGGCGCGGGCAGCGGCAACCTTCGAGGCGGCGGGGGTGGCGGACCGGGTCA
CGCTGGCGGGGCAGAGCTTCTTCGAGCCCCTGCCGTCCGGCGGCGATGTCTACCTGCTAAGCAAGGTGCTGTGCGACTGG
CCGGATCGCGAGGCGACGGCGATTCTGCGGCGCTGCGCGGAGGCCGCGGGCGCGACCGGTCGCGTGGTCGCTTTGGGGGA
AGGCGGCCCGGGATCGCCCGAGTTGTTGATGCTGGTGCTGGTGGGCGGGAAGGACCGGTCTCTGGAGCAGCTCCGGGCGA
TCGCGCGGGATGCGGGGCTGGAGGTGAGCGCCGTGGGGCGGCAAGCAAAGGGGCGCCCGATGGTGGAGTTGCGGGCGGCT
AGCGCGAATCGTACATGA

Upstream 100 bases:

>100_bases
ACCAAAATCACGAGCAGGATCGCGACGACCAGGATTTTCAAAGCGCTTCTCCTCCGACGATGCTAGCGCACTCCGCGCCC
CGGCATGGCATGATGGCGGA

Downstream 100 bases:

>100_bases
TGCGGCCGCCGACCACGGTGAGGCGAACCTTCGCCTCGTGGATCTGGTGGACGGGAAGGCGCGAGAGATCGCGGTCGAAC
AGGACGAAGTCGGCGAGCTT

Product: hydroxyneurosporene-O-methyltransferase

Products: NA

Alternate protein names: COMT [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MEWWQLSDLCTPWCVHVAATLRVPEHIAAGHGEIGQLAAAAAADRDSLERVLRHLVSKGLFAEPSPGVFALNEAARPLLE
EGARIGLDLDGFGGRMAHAWGTLLSAVRTGRPAYHEAFGRPYWEDLEANPPIAASFDALMGVAGHGVPDPNVLPDPADWE
KVRMVVDVGGGAGDLLAAVLRAHPGTRGTLVDLPRTVARAAATFEAAGVADRVTLAGQSFFEPLPSGGDVYLLSKVLCDW
PDREATAILRRCAEAAGATGRVVALGEGGPGSPELLMLVLVGGKDRSLEQLRAIARDAGLEVSAVGRQAKGRPMVELRAA
SANRT

Sequences:

>Translated_325_residues
MEWWQLSDLCTPWCVHVAATLRVPEHIAAGHGEIGQLAAAAAADRDSLERVLRHLVSKGLFAEPSPGVFALNEAARPLLE
EGARIGLDLDGFGGRMAHAWGTLLSAVRTGRPAYHEAFGRPYWEDLEANPPIAASFDALMGVAGHGVPDPNVLPDPADWE
KVRMVVDVGGGAGDLLAAVLRAHPGTRGTLVDLPRTVARAAATFEAAGVADRVTLAGQSFFEPLPSGGDVYLLSKVLCDW
PDREATAILRRCAEAAGATGRVVALGEGGPGSPELLMLVLVGGKDRSLEQLRAIARDAGLEVSAVGRQAKGRPMVELRAA
SANRT
>Mature_325_residues
MEWWQLSDLCTPWCVHVAATLRVPEHIAAGHGEIGQLAAAAAADRDSLERVLRHLVSKGLFAEPSPGVFALNEAARPLLE
EGARIGLDLDGFGGRMAHAWGTLLSAVRTGRPAYHEAFGRPYWEDLEANPPIAASFDALMGVAGHGVPDPNVLPDPADWE
KVRMVVDVGGGAGDLLAAVLRAHPGTRGTLVDLPRTVARAAATFEAAGVADRVTLAGQSFFEPLPSGGDVYLLSKVLCDW
PDREATAILRRCAEAAGATGRVVALGEGGPGSPELLMLVLVGGKDRSLEQLRAIARDAGLEVSAVGRQAKGRPMVELRAA
SANRT

Specific function: Catalyzes the conversion of carminomycin to daunorubicin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016461
- InterPro:   IPR001077
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00891 Methyltransf_2 [H]

EC number: NA

Molecular weight: Translated: 34156; Mature: 34156

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWWQLSDLCTPWCVHVAATLRVPEHIAAGHGEIGQLAAAAAADRDSLERVLRHLVSKGL
CCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
FAEPSPGVFALNEAARPLLEEGARIGLDLDGFGGRMAHAWGTLLSAVRTGRPAYHEAFGR
CCCCCCCEEEECHHHHHHHHCCCEECCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
PYWEDLEANPPIAASFDALMGVAGHGVPDPNVLPDPADWEKVRMVVDVGGGAGDLLAAVL
CCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHHH
RAHPGTRGTLVDLPRTVARAAATFEAAGVADRVTLAGQSFFEPLPSGGDVYLLSKVLCDW
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCC
PDREATAILRRCAEAAGATGRVVALGEGGPGSPELLMLVLVGGKDRSLEQLRAIARDAGL
CCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
EVSAVGRQAKGRPMVELRAASANRT
EEHHHCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MEWWQLSDLCTPWCVHVAATLRVPEHIAAGHGEIGQLAAAAAADRDSLERVLRHLVSKGL
CCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
FAEPSPGVFALNEAARPLLEEGARIGLDLDGFGGRMAHAWGTLLSAVRTGRPAYHEAFGR
CCCCCCCEEEECHHHHHHHHCCCEECCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
PYWEDLEANPPIAASFDALMGVAGHGVPDPNVLPDPADWEKVRMVVDVGGGAGDLLAAVL
CCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHHH
RAHPGTRGTLVDLPRTVARAAATFEAAGVADRVTLAGQSFFEPLPSGGDVYLLSKVLCDW
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCC
PDREATAILRRCAEAAGATGRVVALGEGGPGSPELLMLVLVGGKDRSLEQLRAIARDAGL
CCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
EVSAVGRQAKGRPMVELRAASANRT
EEHHHCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509343; 7601857 [H]