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The map label for this gene is pyc [H]

Identifier: 116624721

GI number: 116624721

Start: 7074954

End: 7078478

Strand: Direct

Name: pyc [H]

Synonym: Acid_5645

Alternate gene names: 116624721

Gene position: 7074954-7078478 (Clockwise)

Preceding gene: 116624720

Following gene: 116624722

Centisome position: 70.99

GC content: 63.52

Gene sequence:

>3525_bases
ATGTTCCGGACATCGCCGGTCCCACCTCTCCACGCAGTCCCCCTCCCTCCTGTTATCCTCAAAAAAGCAGTTCTCACGCA
CGCCCCCATGAAAAAACTCCTTGCACTGAATCGCAGCGAAATTGCTATCCGCATTCTGCGCGCCGCCAACGAGCTCGGCC
TGCGCACGGTGGCCATCTATTCCAAGGAAGACAAGCTCGCCTTGCACCGCTTCAAAGCCGACGAGGCGTACCTGGTCGGC
GAAGGCAAAGGGCCGGTGGAAGCCTACCTGGACGTGGAGGGCATCGTCGCGCTTGCCAAGGAGAAGGGCGTCGACGCGAT
TCATCCCGGCTACGGATTTCTTTCGGAGAACCCGGCGCTGCCGCGCGCCTGCGAACGGGCCGGCATCACATTCGTCGGCC
CCTCGGCGGAGCTGCTCGATCTGCTCGGCGACAAAACGGCGGCGCGGCGCCTAGCCCAGAAGGCGGGGATCCCGCGCGTG
CCCGGCACGGAAGAGGCGGTGACCAGTCCCAAGCAGGCCGAGAAGATCGCGGCCACGATCGGGTATCCGCTGATTATCAA
GGCGGCCTTCGGCGGCGGCGGCCGCGGCATGCGCGTGGTGGACAAGGCTCCGGATTTCGCGGGCAAGCTGGAAGAGGCAC
GCCGCGAATCGGCCGCGGCCTTCGGCAACGACGCAGTCTTCCTGGAGCGCTTCGTCCGCCGCGCCAAGCACATCGAAGTG
CAGATTCTGGGCGACCGGCACGGCAACATTCTGCATCTTTACGAGCGCGATTGCTCGGTGCAGCGCCGCCATCAGAAGGT
GGTCGAAGTGGCGCCCGCCGTCGGATTGGATCCGAAGATCCGCGCGCAGTTGGCGGATGCGGCGGTGACGCTGGCGCGCG
CGGCGGGCTATACGAACGCCGGCACCGTCGAATTCCTGGTGGACGCCGACTCCGGCGAGTGGTTCTTCATTGAGGTCAAC
CCGCGCATTCAGGTGGAACACACCGTCACCGAAATGGTGACCGGCATCGACCTGGTGCGCAGCCAGATCCAGGTGGCCCA
GGGGCTGCAATTGCACGGCCCCGAGATGAACCTGCCCACGCAGGACAAGGTGCCGCTTTACGGCTACGCGCTGCAATGCC
GGATCACCACCGAGGATCCGGCGAACGGCTTCGTGCCGGATTACGGCAAGATCCACACCTACCGTTCGCCGGCCGGCTTC
GGCATCCGGCTGGACGGCGGGTCGGCCTACTCGGGCGCGGTGATCACGCCCTTCTACGATTCGCTGCTGGTGAAGACAAC
CGCATGGGGCCGCGAGTTTCCGCACGCCTGCCAGCGCATGGATCGCAGCCTGCGCGAGTTCCGCGTGCGCGGCGTGAAGA
CGAACATTCCCTTCCTCGAAAACGTAGTCAATCATGCGGATTTCCAGGCCGGGAAAGTCAGCACCCGCTGGCTGGAAGAG
ACTCCGGCGCTCTTCAAGTTCGAGGCACGTCGCGACCGCGCCACCAAGCTGCTCACGTATCTCGCGGAAGTGATCGTCAA
TGGAAATCCGCAGGTCGCAGGAAAATTGCGGCCGGCGAAGATCGGCACGCCGCCGATCCCGGCGCACGATAGTTCCGAGG
CGCCCAAAGGCACGCGCCAACTGCTGCGCGAGCTCGGGCCCAGTGGCTTCGCCGAGTGGACCGGGAAGCAGAAGCGCCTG
CTGCTGACCGACACCACCTTCCGCGACGCGCACCAATCGCTGCTGGCGACGCGGGTGCGCTCGTACGATATGCTGGCAAT
CGCCAACTTCGTTTCGCACAGGCTGCACAATCTGTACAGCGTCGAAATGTGGGGCGGCGCAACCTTCGACGTGACCATGC
GCTTCCTGCATGAGGATCCCTTCGCGCGCCTGCGCCAACTGCGCGCGGCAATCCCGAACATCTGCTTCCAGATGCTGCTG
CGCGCTTCGAACGCAGTCGGCTATACGGCGTATCCGGATAACGCGGTCGCGGAGTTCATTTACGAAGCCTCCGCTCAGGG
CATCGATATCTTCCGGATTTTCGATTCGCTCAACTGGCTGCCCAACATGAAGGCGTCCATGGCGGCGGTCCGCAAGACGC
GCTCGGTCTGCGAAGCGGCCATCTGCTACACCGGCGATATCCTCGACCCGAAGCGCGATAAATACTCGCTGGATTATTAC
GTGCGCATGGCCAAAGAGTTGGAGAAGATGGGCGCTCACGTGCTCGCGATTAAGGACATGGCGGGCCTGTGCCGTCCTTA
CGCAGCCGAGAAGCTGGTGAAGGCGCTGCGGCAGGAGGTGGGCATTCCGATTCACTTCCACACGCACGATACCAGCGGTT
TGAACGCTGCGTCGATCTTGAAGGCGGCCGAATCCGGCGTACACGTGGCCGATGGCGCGGCGGCCTCGATGAGCGGCACC
ACCAGCCAACCGAATCTCAACTCCATCGTCGCCGCGCTGGCGCACACCAAGCGCGACACCGGGCTCGATCTGGACGCGCT
CAATCAATACGCGGACTACTGGGAAGTCGTGCGGGAGTTCTACGCGCCTTTCGATACGGGTCCGAAATCGGGCTCGGCCG
AGGTCTACGAGCACGAGATGCCGGGCGGCCAGTACACGAATCTGAAGGAACAGGCCGAATCGATGGGCCTGGGCGCGCGC
TGGCACGAAATCGCGCGAACGTACGCGGAGGTCAACCTGGCCTTCGGCGACATCGTCAAGGTGACGCCTTCCAGCAAGGT
GGTCGGCGACATGGCGATCTTCCTGGTCAATCACAATATGACCATCGGGCAGTTCGAGAAGCTGACGCCCGATCACAATT
TGACGCTGCCGGCGAGCGTGATCGACATGTTCATGGGATCGCTCGGCGAGCCTGAGGGCGGGTGGCCGAAGCATCTGCAG
AAGATCATCCTCAAGGGCGCCAAGCCGCAACGCGGCCGTCCAGGCGCACAACTGCCGCCGGTGAACCTCGACGAGACCGC
CGCCTCGTTGGAGAAGAAGATCGCGCGCAAGCCTTCGCACGATGAAGTGCTGAGCTATCTCATGTACCCCGACGTCTTCC
TGAAGTTCGCGCGCGCCCGGCAGAATTGGGGCGACGTGGACGTACTGCCCACGCCGGAATTTTATTACGGCATGGAGCGC
AGCGCCGATATCGCCGTGGAACTGGAACCGGGCAAGGCGCTGGTCATCAAGTTCCTGACCGTCGGCGAACCGCATCCCGA
CGGCACGCGCACCGTCTTCTTCGAACTCAACGGCCAGCCGCGCGAAGTGACTGTGCGCGATAGCAGCCTGGAAGTCAAAG
AACAGGGACGCCCGAAGGCCGACCCTGGAAAGCCCGGCAACATCGGCGCGCCGATCCCAGGCGTGGTTTCCACCGTCGCC
GTGGAGTTGAACCAGATCCTGAAGAAGGGCGATCGTTTGCTGGTGATGGAAGCCATGAAAATGCAGAGCACCGTCTACGC
TCCCGTCGCCGGCAAGGTGACGCAGCTGCTGGTAACGCCCGGCCAGCAGGTGGAGGCGAAGGATCTGCTGCTAGTCATCG
AGTAG

Upstream 100 bases:

>100_bases
GAATTCGATTTTTGTGTTGGATGAGCTCCCCGAAGAGTACGCGAAGTTTGCGGACATCAACGCGGCCCATTACAACTAGT
TTCTAGTTCAAGAACCGGCG

Downstream 100 bases:

>100_bases
GACGGGCCTGCGGCCTGTCGCGCTAATCGGCTTTTGCTAACATGATCTTCGACATGCCGAAGATCAGAGGACTTCGTTGG
TGGATGATCGGGCTGATCAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1174; Mature: 1174

Protein sequence:

>1174_residues
MFRTSPVPPLHAVPLPPVILKKAVLTHAPMKKLLALNRSEIAIRILRAANELGLRTVAIYSKEDKLALHRFKADEAYLVG
EGKGPVEAYLDVEGIVALAKEKGVDAIHPGYGFLSENPALPRACERAGITFVGPSAELLDLLGDKTAARRLAQKAGIPRV
PGTEEAVTSPKQAEKIAATIGYPLIIKAAFGGGGRGMRVVDKAPDFAGKLEEARRESAAAFGNDAVFLERFVRRAKHIEV
QILGDRHGNILHLYERDCSVQRRHQKVVEVAPAVGLDPKIRAQLADAAVTLARAAGYTNAGTVEFLVDADSGEWFFIEVN
PRIQVEHTVTEMVTGIDLVRSQIQVAQGLQLHGPEMNLPTQDKVPLYGYALQCRITTEDPANGFVPDYGKIHTYRSPAGF
GIRLDGGSAYSGAVITPFYDSLLVKTTAWGREFPHACQRMDRSLREFRVRGVKTNIPFLENVVNHADFQAGKVSTRWLEE
TPALFKFEARRDRATKLLTYLAEVIVNGNPQVAGKLRPAKIGTPPIPAHDSSEAPKGTRQLLRELGPSGFAEWTGKQKRL
LLTDTTFRDAHQSLLATRVRSYDMLAIANFVSHRLHNLYSVEMWGGATFDVTMRFLHEDPFARLRQLRAAIPNICFQMLL
RASNAVGYTAYPDNAVAEFIYEASAQGIDIFRIFDSLNWLPNMKASMAAVRKTRSVCEAAICYTGDILDPKRDKYSLDYY
VRMAKELEKMGAHVLAIKDMAGLCRPYAAEKLVKALRQEVGIPIHFHTHDTSGLNAASILKAAESGVHVADGAAASMSGT
TSQPNLNSIVAALAHTKRDTGLDLDALNQYADYWEVVREFYAPFDTGPKSGSAEVYEHEMPGGQYTNLKEQAESMGLGAR
WHEIARTYAEVNLAFGDIVKVTPSSKVVGDMAIFLVNHNMTIGQFEKLTPDHNLTLPASVIDMFMGSLGEPEGGWPKHLQ
KIILKGAKPQRGRPGAQLPPVNLDETAASLEKKIARKPSHDEVLSYLMYPDVFLKFARARQNWGDVDVLPTPEFYYGMER
SADIAVELEPGKALVIKFLTVGEPHPDGTRTVFFELNGQPREVTVRDSSLEVKEQGRPKADPGKPGNIGAPIPGVVSTVA
VELNQILKKGDRLLVMEAMKMQSTVYAPVAGKVTQLLVTPGQQVEAKDLLLVIE

Sequences:

>Translated_1174_residues
MFRTSPVPPLHAVPLPPVILKKAVLTHAPMKKLLALNRSEIAIRILRAANELGLRTVAIYSKEDKLALHRFKADEAYLVG
EGKGPVEAYLDVEGIVALAKEKGVDAIHPGYGFLSENPALPRACERAGITFVGPSAELLDLLGDKTAARRLAQKAGIPRV
PGTEEAVTSPKQAEKIAATIGYPLIIKAAFGGGGRGMRVVDKAPDFAGKLEEARRESAAAFGNDAVFLERFVRRAKHIEV
QILGDRHGNILHLYERDCSVQRRHQKVVEVAPAVGLDPKIRAQLADAAVTLARAAGYTNAGTVEFLVDADSGEWFFIEVN
PRIQVEHTVTEMVTGIDLVRSQIQVAQGLQLHGPEMNLPTQDKVPLYGYALQCRITTEDPANGFVPDYGKIHTYRSPAGF
GIRLDGGSAYSGAVITPFYDSLLVKTTAWGREFPHACQRMDRSLREFRVRGVKTNIPFLENVVNHADFQAGKVSTRWLEE
TPALFKFEARRDRATKLLTYLAEVIVNGNPQVAGKLRPAKIGTPPIPAHDSSEAPKGTRQLLRELGPSGFAEWTGKQKRL
LLTDTTFRDAHQSLLATRVRSYDMLAIANFVSHRLHNLYSVEMWGGATFDVTMRFLHEDPFARLRQLRAAIPNICFQMLL
RASNAVGYTAYPDNAVAEFIYEASAQGIDIFRIFDSLNWLPNMKASMAAVRKTRSVCEAAICYTGDILDPKRDKYSLDYY
VRMAKELEKMGAHVLAIKDMAGLCRPYAAEKLVKALRQEVGIPIHFHTHDTSGLNAASILKAAESGVHVADGAAASMSGT
TSQPNLNSIVAALAHTKRDTGLDLDALNQYADYWEVVREFYAPFDTGPKSGSAEVYEHEMPGGQYTNLKEQAESMGLGAR
WHEIARTYAEVNLAFGDIVKVTPSSKVVGDMAIFLVNHNMTIGQFEKLTPDHNLTLPASVIDMFMGSLGEPEGGWPKHLQ
KIILKGAKPQRGRPGAQLPPVNLDETAASLEKKIARKPSHDEVLSYLMYPDVFLKFARARQNWGDVDVLPTPEFYYGMER
SADIAVELEPGKALVIKFLTVGEPHPDGTRTVFFELNGQPREVTVRDSSLEVKEQGRPKADPGKPGNIGAPIPGVVSTVA
VELNQILKKGDRLLVMEAMKMQSTVYAPVAGKVTQLLVTPGQQVEAKDLLLVIE
>Mature_1174_residues
MFRTSPVPPLHAVPLPPVILKKAVLTHAPMKKLLALNRSEIAIRILRAANELGLRTVAIYSKEDKLALHRFKADEAYLVG
EGKGPVEAYLDVEGIVALAKEKGVDAIHPGYGFLSENPALPRACERAGITFVGPSAELLDLLGDKTAARRLAQKAGIPRV
PGTEEAVTSPKQAEKIAATIGYPLIIKAAFGGGGRGMRVVDKAPDFAGKLEEARRESAAAFGNDAVFLERFVRRAKHIEV
QILGDRHGNILHLYERDCSVQRRHQKVVEVAPAVGLDPKIRAQLADAAVTLARAAGYTNAGTVEFLVDADSGEWFFIEVN
PRIQVEHTVTEMVTGIDLVRSQIQVAQGLQLHGPEMNLPTQDKVPLYGYALQCRITTEDPANGFVPDYGKIHTYRSPAGF
GIRLDGGSAYSGAVITPFYDSLLVKTTAWGREFPHACQRMDRSLREFRVRGVKTNIPFLENVVNHADFQAGKVSTRWLEE
TPALFKFEARRDRATKLLTYLAEVIVNGNPQVAGKLRPAKIGTPPIPAHDSSEAPKGTRQLLRELGPSGFAEWTGKQKRL
LLTDTTFRDAHQSLLATRVRSYDMLAIANFVSHRLHNLYSVEMWGGATFDVTMRFLHEDPFARLRQLRAAIPNICFQMLL
RASNAVGYTAYPDNAVAEFIYEASAQGIDIFRIFDSLNWLPNMKASMAAVRKTRSVCEAAICYTGDILDPKRDKYSLDYY
VRMAKELEKMGAHVLAIKDMAGLCRPYAAEKLVKALRQEVGIPIHFHTHDTSGLNAASILKAAESGVHVADGAAASMSGT
TSQPNLNSIVAALAHTKRDTGLDLDALNQYADYWEVVREFYAPFDTGPKSGSAEVYEHEMPGGQYTNLKEQAESMGLGAR
WHEIARTYAEVNLAFGDIVKVTPSSKVVGDMAIFLVNHNMTIGQFEKLTPDHNLTLPASVIDMFMGSLGEPEGGWPKHLQ
KIILKGAKPQRGRPGAQLPPVNLDETAASLEKKIARKPSHDEVLSYLMYPDVFLKFARARQNWGDVDVLPTPEFYYGMER
SADIAVELEPGKALVIKFLTVGEPHPDGTRTVFFELNGQPREVTVRDSSLEVKEQGRPKADPGKPGNIGAPIPGVVSTVA
VELNQILKKGDRLLVMEAMKMQSTVYAPVAGKVTQLLVTPGQQVEAKDLLLVIE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1154, Percent_Identity=50.3466204506066, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1154, Percent_Identity=50.3466204506066, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1154, Percent_Identity=50.3466204506066, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=461, Percent_Identity=40.997830802603, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI189095269, Length=476, Percent_Identity=39.7058823529412, Blast_Score=343, Evalue=5e-94,
Organism=Homo sapiens, GI65506442, Length=458, Percent_Identity=40.174672489083, Blast_Score=340, Evalue=6e-93,
Organism=Homo sapiens, GI295821183, Length=458, Percent_Identity=40.174672489083, Blast_Score=339, Evalue=1e-92,
Organism=Homo sapiens, GI38679977, Length=509, Percent_Identity=32.0235756385069, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI38679967, Length=509, Percent_Identity=32.0235756385069, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI38679971, Length=509, Percent_Identity=32.0235756385069, Blast_Score=253, Evalue=7e-67,
Organism=Homo sapiens, GI38679960, Length=509, Percent_Identity=32.2200392927308, Blast_Score=253, Evalue=8e-67,
Organism=Homo sapiens, GI38679974, Length=509, Percent_Identity=32.2200392927308, Blast_Score=253, Evalue=8e-67,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=32.3529411764706, Blast_Score=247, Evalue=5e-65,
Organism=Homo sapiens, GI18105007, Length=239, Percent_Identity=26.3598326359833, Blast_Score=74, Evalue=9e-13,
Organism=Escherichia coli, GI1789654, Length=456, Percent_Identity=43.2017543859649, Blast_Score=357, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=1181, Percent_Identity=49.5342929720576, Blast_Score=1122, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=452, Percent_Identity=41.5929203539823, Blast_Score=354, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17567343, Length=454, Percent_Identity=40.5286343612335, Blast_Score=337, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI71997168, Length=474, Percent_Identity=32.9113924050633, Blast_Score=236, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI71997163, Length=474, Percent_Identity=32.9113924050633, Blast_Score=235, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI133931226, Length=495, Percent_Identity=30.9090909090909, Blast_Score=217, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1160, Percent_Identity=47.5, Blast_Score=1045, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=47.5, Blast_Score=1027, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=446, Percent_Identity=41.2556053811659, Blast_Score=329, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6323863, Length=436, Percent_Identity=34.1743119266055, Blast_Score=254, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6324343, Length=516, Percent_Identity=31.3953488372093, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24652212, Length=1156, Percent_Identity=51.2110726643599, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1156, Percent_Identity=51.2110726643599, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1156, Percent_Identity=51.2110726643599, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1156, Percent_Identity=51.2110726643599, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1156, Percent_Identity=51.2110726643599, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1172, Percent_Identity=50.6825938566553, Blast_Score=1122, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1172, Percent_Identity=50.6825938566553, Blast_Score=1122, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1172, Percent_Identity=50.6825938566553, Blast_Score=1122, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1172, Percent_Identity=50.6825938566553, Blast_Score=1122, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1172, Percent_Identity=50.6825938566553, Blast_Score=1122, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=454, Percent_Identity=41.4096916299559, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24651759, Length=415, Percent_Identity=40.7228915662651, Blast_Score=322, Evalue=1e-87,
Organism=Drosophila melanogaster, GI161076409, Length=505, Percent_Identity=32.0792079207921, Blast_Score=248, Evalue=3e-65,
Organism=Drosophila melanogaster, GI161076407, Length=505, Percent_Identity=32.0792079207921, Blast_Score=248, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24586460, Length=505, Percent_Identity=32.0792079207921, Blast_Score=248, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24586458, Length=505, Percent_Identity=32.0792079207921, Blast_Score=247, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128904; Mature: 128904

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50975 ATP_GRASP ; PS00165 DEHYDRATASE_SER_THR ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTSPVPPLHAVPLPPVILKKAVLTHAPMKKLLALNRSEIAIRILRAANELGLRTVAIY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEE
SKEDKLALHRFKADEAYLVGEGKGPVEAYLDVEGIVALAKEKGVDAIHPGYGFLSENPAL
CCCCCHHHHHCCCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCEECCCCCCCCCCCCC
PRACERAGITFVGPSAELLDLLGDKTAARRLAQKAGIPRVPGTEEAVTSPKQAEKIAATI
CHHHHHCCCEEECCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHC
GYPLIIKAAFGGGGRGMRVVDKAPDFAGKLEEARRESAAAFGNDAVFLERFVRRAKHIEV
CCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEE
QILGDRHGNILHLYERDCSVQRRHQKVVEVAPAVGLDPKIRAQLADAAVTLARAAGYTNA
EEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTVEFLVDADSGEWFFIEVNPRIQVEHTVTEMVTGIDLVRSQIQVAQGLQLHGPEMNLPT
CEEEEEEECCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
QDKVPLYGYALQCRITTEDPANGFVPDYGKIHTYRSPAGFGIRLDGGSAYSGAVITPFYD
CCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCEECHHHH
SLLVKTTAWGREFPHACQRMDRSLREFRVRGVKTNIPFLENVVNHADFQAGKVSTRWLEE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
TPALFKFEARRDRATKLLTYLAEVIVNGNPQVAGKLRPAKIGTPPIPAHDSSEAPKGTRQ
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHH
LLRELGPSGFAEWTGKQKRLLLTDTTFRDAHQSLLATRVRSYDMLAIANFVSHRLHNLYS
HHHHCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VEMWGGATFDVTMRFLHEDPFARLRQLRAAIPNICFQMLLRASNAVGYTAYPDNAVAEFI
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
YEASAQGIDIFRIFDSLNWLPNMKASMAAVRKTRSVCEAAICYTGDILDPKRDKYSLDYY
HHHCCCCCHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VRMAKELEKMGAHVLAIKDMAGLCRPYAAEKLVKALRQEVGIPIHFHTHDTSGLNAASIL
HHHHHHHHHCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
KAAESGVHVADGAAASMSGTTSQPNLNSIVAALAHTKRDTGLDLDALNQYADYWEVVREF
HHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
YAPFDTGPKSGSAEVYEHEMPGGQYTNLKEQAESMGLGARWHEIARTYAEVNLAFGDIVK
HCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEEEECCEEE
VTPSSKVVGDMAIFLVNHNMTIGQFEKLTPDHNLTLPASVIDMFMGSLGEPEGGWPKHLQ
ECCCCHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
KIILKGAKPQRGRPGAQLPPVNLDETAASLEKKIARKPSHDEVLSYLMYPDVFLKFARAR
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QNWGDVDVLPTPEFYYGMERSADIAVELEPGKALVIKFLTVGEPHPDGTRTVFFELNGQP
CCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEEEECCCC
REVTVRDSSLEVKEQGRPKADPGKPGNIGAPIPGVVSTVAVELNQILKKGDRLLVMEAMK
CEEEEECCCEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHH
MQSTVYAPVAGKVTQLLVTPGQQVEAKDLLLVIE
HHHHEECCCCCCHHEEEECCCCCCCCCCEEEEEC
>Mature Secondary Structure
MFRTSPVPPLHAVPLPPVILKKAVLTHAPMKKLLALNRSEIAIRILRAANELGLRTVAIY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEE
SKEDKLALHRFKADEAYLVGEGKGPVEAYLDVEGIVALAKEKGVDAIHPGYGFLSENPAL
CCCCCHHHHHCCCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCEECCCCCCCCCCCCC
PRACERAGITFVGPSAELLDLLGDKTAARRLAQKAGIPRVPGTEEAVTSPKQAEKIAATI
CHHHHHCCCEEECCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHC
GYPLIIKAAFGGGGRGMRVVDKAPDFAGKLEEARRESAAAFGNDAVFLERFVRRAKHIEV
CCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEE
QILGDRHGNILHLYERDCSVQRRHQKVVEVAPAVGLDPKIRAQLADAAVTLARAAGYTNA
EEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTVEFLVDADSGEWFFIEVNPRIQVEHTVTEMVTGIDLVRSQIQVAQGLQLHGPEMNLPT
CEEEEEEECCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
QDKVPLYGYALQCRITTEDPANGFVPDYGKIHTYRSPAGFGIRLDGGSAYSGAVITPFYD
CCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCEECHHHH
SLLVKTTAWGREFPHACQRMDRSLREFRVRGVKTNIPFLENVVNHADFQAGKVSTRWLEE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
TPALFKFEARRDRATKLLTYLAEVIVNGNPQVAGKLRPAKIGTPPIPAHDSSEAPKGTRQ
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHH
LLRELGPSGFAEWTGKQKRLLLTDTTFRDAHQSLLATRVRSYDMLAIANFVSHRLHNLYS
HHHHCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VEMWGGATFDVTMRFLHEDPFARLRQLRAAIPNICFQMLLRASNAVGYTAYPDNAVAEFI
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
YEASAQGIDIFRIFDSLNWLPNMKASMAAVRKTRSVCEAAICYTGDILDPKRDKYSLDYY
HHHCCCCCHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VRMAKELEKMGAHVLAIKDMAGLCRPYAAEKLVKALRQEVGIPIHFHTHDTSGLNAASIL
HHHHHHHHHCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
KAAESGVHVADGAAASMSGTTSQPNLNSIVAALAHTKRDTGLDLDALNQYADYWEVVREF
HHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
YAPFDTGPKSGSAEVYEHEMPGGQYTNLKEQAESMGLGARWHEIARTYAEVNLAFGDIVK
HCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEEEECCEEE
VTPSSKVVGDMAIFLVNHNMTIGQFEKLTPDHNLTLPASVIDMFMGSLGEPEGGWPKHLQ
ECCCCHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
KIILKGAKPQRGRPGAQLPPVNLDETAASLEKKIARKPSHDEVLSYLMYPDVFLKFARAR
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QNWGDVDVLPTPEFYYGMERSADIAVELEPGKALVIKFLTVGEPHPDGTRTVFFELNGQP
CCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCEEEEEEECCCC
REVTVRDSSLEVKEQGRPKADPGKPGNIGAPIPGVVSTVAVELNQILKKGDRLLVMEAMK
CEEEEECCCEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHH
MQSTVYAPVAGKVTQLLVTPGQQVEAKDLLLVIE
HHHHEECCCCCCHHEEEECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]