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The map label for this gene is nagA [H]

Identifier: 116624648

GI number: 116624648

Start: 6984378

End: 6985448

Strand: Reverse

Name: nagA [H]

Synonym: Acid_5572

Alternate gene names: 116624648

Gene position: 6985448-6984378 (Counterclockwise)

Preceding gene: 116624649

Following gene: 116624646

Centisome position: 70.1

GC content: 66.76

Gene sequence:

>1071_bases
ATGACCACCTTGAATTGTTCCGGGAGTTATTCCTCGCCCGGCTTCGTGGACCTGCAAGTGAATGGATTTGCGGGCGTGGA
CTACAACCATCCGCGAAGTTCGATGGAAGAAATCGGACGATCGCTGCGAGCCCAGTTCGCGGCCGGCGTGACGCGGCTCT
ATCCCACGGTGATCACGGGAGCGCCGGATGAGATGGCTGCGTGCCTGCGCAACCTGGCGGCGGCGCAGGCGGCGCTGCCC
GAGGGTGAGGCCATGGCGGGATTCCACGTGGAGGGCCCGCACATCTCGCCGGAGGATGGACCGCGTGGCGCACACCCGCG
GCAATGGGTGCGCCCGCCGGACGCGGGCGAGTTCGCGCGCTGGCAGGAAGCGGCCGGCGGCGCGATCCGGATTATCACGC
TCTCGCCGGAGTGGCCCGGCGCCGCGCGCTACATCGAACACATCACAGCGCAGGGAGTGGTGGCGTCGATCGGGCACACG
CAGGCGAGCGCGGAGCAGATTGCGGAGGCCGTGGCGGCGGGTGCGACGCTATCCACGCACCTGGGGAATGGAGCCCATCA
GTTGCTGCGACGGCATCCGAACTACATCTGGGAACAACTGGCGGAGGACCGTCTGATGGCGGGCTTCATCGTGGACGGCA
TTCATCTTGGCGCGTCGTTTCTGAAGGCGGCGATCCGCGCCAAGGGGCTCGAGCGTGCGGTGCTGGTGACGGATGCGGCA
ACACCGGCGGGCGCAGTTCCGGGCCGCTATCTGCTCGCCGATCAGGCAGTGGAATTGACGCAGGACGGGCGCGTGGTGCT
GGCCGGGACCGACCGCTTGGCGGGAAGCGCATTGAGCATGAATCGCGGCGTGGCAAACGTGATGCGACTGGCCGGGTTAA
CGCTGGACGAGGCGGTCCGGATGGCGACCGAAAATGCGGCGCGGGCCGGCAAGGTTGCGGTACACCCGGAGGACAAGGTG
GAGTTTCGCCTGACCGCCGCGGGTGATGTTGAAGTGGTGCGCACCTGGCTTGCCGGGCGGCTCACTCATGATTCAACTCT
CAGCCGTGACGCGCAAGCACCTCTTCTTTGA

Upstream 100 bases:

>100_bases
GTGTTAGCGCCAGAGTGAATTTCGCCTTTTGCACACCTTTTTTGCCGCCTGAAAACATGCACTTACAAGTGCGAGTGTGT
GGCAAACTTGTGAATAAATC

Downstream 100 bases:

>100_bases
TCTCGATTTCCTTGCGCTCGGATTTGATGCCAAGACGCAGGCGGCCGAAGATGCTCATGTAGATGTTGGCCACCCAGACC
AGGGCGAACAAACCGATCAG

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTLNCSGSYSSPGFVDLQVNGFAGVDYNHPRSSMEEIGRSLRAQFAAGVTRLYPTVITGAPDEMAACLRNLAAAQAALP
EGEAMAGFHVEGPHISPEDGPRGAHPRQWVRPPDAGEFARWQEAAGGAIRIITLSPEWPGAARYIEHITAQGVVASIGHT
QASAEQIAEAVAAGATLSTHLGNGAHQLLRRHPNYIWEQLAEDRLMAGFIVDGIHLGASFLKAAIRAKGLERAVLVTDAA
TPAGAVPGRYLLADQAVELTQDGRVVLAGTDRLAGSALSMNRGVANVMRLAGLTLDEAVRMATENAARAGKVAVHPEDKV
EFRLTAAGDVEVVRTWLAGRLTHDSTLSRDAQAPLL

Sequences:

>Translated_356_residues
MTTLNCSGSYSSPGFVDLQVNGFAGVDYNHPRSSMEEIGRSLRAQFAAGVTRLYPTVITGAPDEMAACLRNLAAAQAALP
EGEAMAGFHVEGPHISPEDGPRGAHPRQWVRPPDAGEFARWQEAAGGAIRIITLSPEWPGAARYIEHITAQGVVASIGHT
QASAEQIAEAVAAGATLSTHLGNGAHQLLRRHPNYIWEQLAEDRLMAGFIVDGIHLGASFLKAAIRAKGLERAVLVTDAA
TPAGAVPGRYLLADQAVELTQDGRVVLAGTDRLAGSALSMNRGVANVMRLAGLTLDEAVRMATENAARAGKVAVHPEDKV
EFRLTAAGDVEVVRTWLAGRLTHDSTLSRDAQAPLL
>Mature_355_residues
TTLNCSGSYSSPGFVDLQVNGFAGVDYNHPRSSMEEIGRSLRAQFAAGVTRLYPTVITGAPDEMAACLRNLAAAQAALPE
GEAMAGFHVEGPHISPEDGPRGAHPRQWVRPPDAGEFARWQEAAGGAIRIITLSPEWPGAARYIEHITAQGVVASIGHTQ
ASAEQIAEAVAAGATLSTHLGNGAHQLLRRHPNYIWEQLAEDRLMAGFIVDGIHLGASFLKAAIRAKGLERAVLVTDAAT
PAGAVPGRYLLADQAVELTQDGRVVLAGTDRLAGSALSMNRGVANVMRLAGLTLDEAVRMATENAARAGKVAVHPEDKVE
FRLTAAGDVEVVRTWLAGRLTHDSTLSRDAQAPLL

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=269, Percent_Identity=35.3159851301115, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI224922791, Length=349, Percent_Identity=30.945558739255, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1786892, Length=305, Percent_Identity=34.4262295081967, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17553768, Length=318, Percent_Identity=34.2767295597484, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920392, Length=360, Percent_Identity=30.5555555555556, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281361140, Length=373, Percent_Identity=29.4906166219839, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 37591; Mature: 37460

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLNCSGSYSSPGFVDLQVNGFAGVDYNHPRSSMEEIGRSLRAQFAAGVTRLYPTVITG
CCEECCCCCCCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDEMAACLRNLAAAQAALPEGEAMAGFHVEGPHISPEDGPRGAHPRQWVRPPDAGEFAR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
WQEAAGGAIRIITLSPEWPGAARYIEHITAQGVVASIGHTQASAEQIAEAVAAGATLSTH
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCHHHHH
LGNGAHQLLRRHPNYIWEQLAEDRLMAGFIVDGIHLGASFLKAAIRAKGLERAVLVTDAA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
TPAGAVPGRYLLADQAVELTQDGRVVLAGTDRLAGSALSMNRGVANVMRLAGLTLDEAVR
CCCCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
MATENAARAGKVAVHPEDKVEFRLTAAGDVEVVRTWLAGRLTHDSTLSRDAQAPLL
HHHHHHHHCCEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
TTLNCSGSYSSPGFVDLQVNGFAGVDYNHPRSSMEEIGRSLRAQFAAGVTRLYPTVITG
CEECCCCCCCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDEMAACLRNLAAAQAALPEGEAMAGFHVEGPHISPEDGPRGAHPRQWVRPPDAGEFAR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
WQEAAGGAIRIITLSPEWPGAARYIEHITAQGVVASIGHTQASAEQIAEAVAAGATLSTH
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCHHHHH
LGNGAHQLLRRHPNYIWEQLAEDRLMAGFIVDGIHLGASFLKAAIRAKGLERAVLVTDAA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
TPAGAVPGRYLLADQAVELTQDGRVVLAGTDRLAGSALSMNRGVANVMRLAGLTLDEAVR
CCCCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
MATENAARAGKVAVHPEDKVEFRLTAAGDVEVVRTWLAGRLTHDSTLSRDAQAPLL
HHHHHHHHCCEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]