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The map label for this gene is ppa [H]

Identifier: 116624618

GI number: 116624618

Start: 6945838

End: 6946413

Strand: Reverse

Name: ppa [H]

Synonym: Acid_5542

Alternate gene names: 116624618

Gene position: 6946413-6945838 (Counterclockwise)

Preceding gene: 116624619

Following gene: 116624614

Centisome position: 69.7

GC content: 59.03

Gene sequence:

>576_bases
ATGCGCTGCTACGATAGTGAGTGCATGAGCCTTTACGACTTGGAGCCGGGTCCGGATTGCCCTGAGCTCGTCCGCATGAT
CGTCGAGATCCCGAAGAATTCCAGCAACAAATACGAATACGATGGCAAGCTCGGTGTTTTTCGCCTGGACCGCTCGCTCT
ATTCCGCGGTCCATTATCCCGGCGACTACGGTTTCATTCCCGGGACCCTCGCCGAAGACGGCGATCCGCTGGATGTGCTG
ACGCTGGTTGACGTACCCAGTTTTCCGGGAGTCCTGATGATGGTGCGTCCCGTGGGCGTACTCGCGATGGTGGACCAGGA
GGAGCCGGACGAAAAAATTCTCGCCGTTCCCAACCACAACCCCCGCTTCGATCAGATCCACACCATCGACCAGGTCTTCC
AGCACAACCTGCGCGAGATCGAACACTTCTTCGCCATCTATAAAGAGCTCGAAGGCAAGCGCACCGTCATGCAAGGCTGG
AAAGGCCCTCGCGAAGCCCGTGATGTGATCCGCCGCTCCCGCGAACGCTACCTCGCGGCGCATCCGGAATTGCAGCTCGA
CCCCGAAGCGTCCTAA

Upstream 100 bases:

>100_bases
ACCAATTACTTCGGCACCACCGTCGCCCAGACGCTGAAGACCTGGACCACCATGAAGATCATCGCCTCCCTGCTGGGGCT
CGCCATCATGCTCACCGCGC

Downstream 100 bases:

>100_bases
CTAAGTACGCCATTTCGGAAGTTCGGCGACGTATCGAGCAGACGCTTGCTGACGCGCGCGGCTCCGTTCGGAGCCCCGAC
CGTAAGGGAGGGTCCTCCCC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MRCYDSECMSLYDLEPGPDCPELVRMIVEIPKNSSNKYEYDGKLGVFRLDRSLYSAVHYPGDYGFIPGTLAEDGDPLDVL
TLVDVPSFPGVLMMVRPVGVLAMVDQEEPDEKILAVPNHNPRFDQIHTIDQVFQHNLREIEHFFAIYKELEGKRTVMQGW
KGPREARDVIRRSRERYLAAHPELQLDPEAS

Sequences:

>Translated_191_residues
MRCYDSECMSLYDLEPGPDCPELVRMIVEIPKNSSNKYEYDGKLGVFRLDRSLYSAVHYPGDYGFIPGTLAEDGDPLDVL
TLVDVPSFPGVLMMVRPVGVLAMVDQEEPDEKILAVPNHNPRFDQIHTIDQVFQHNLREIEHFFAIYKELEGKRTVMQGW
KGPREARDVIRRSRERYLAAHPELQLDPEAS
>Mature_191_residues
MRCYDSECMSLYDLEPGPDCPELVRMIVEIPKNSSNKYEYDGKLGVFRLDRSLYSAVHYPGDYGFIPGTLAEDGDPLDVL
TLVDVPSFPGVLMMVRPVGVLAMVDQEEPDEKILAVPNHNPRFDQIHTIDQVFQHNLREIEHFFAIYKELEGKRTVMQGW
KGPREARDVIRRSRERYLAAHPELQLDPEAS

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=39.5348837209302, Blast_Score=117, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319483, Length=185, Percent_Identity=25.4054054054054, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21921; Mature: 21921

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCYDSECMSLYDLEPGPDCPELVRMIVEIPKNSSNKYEYDGKLGVFRLDRSLYSAVHYP
CCCCCCHHHEEECCCCCCCHHHHHHHHHHCCCCCCCCEEECCCEEHEEHHHHHHHHHCCC
GDYGFIPGTLAEDGDPLDVLTLVDVPSFPGVLMMVRPVGVLAMVDQEEPDEKILAVPNHN
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCEEEEECCCCCCCCEEECCCCC
PRFDQIHTIDQVFQHNLREIEHFFAIYKELEGKRTVMQGWKGPREARDVIRRSRERYLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHC
HPELQLDPEAS
CCCCCCCCCCC
>Mature Secondary Structure
MRCYDSECMSLYDLEPGPDCPELVRMIVEIPKNSSNKYEYDGKLGVFRLDRSLYSAVHYP
CCCCCCHHHEEECCCCCCCHHHHHHHHHHCCCCCCCCEEECCCEEHEEHHHHHHHHHCCC
GDYGFIPGTLAEDGDPLDVLTLVDVPSFPGVLMMVRPVGVLAMVDQEEPDEKILAVPNHN
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCEEEEECCCCCCCCEEECCCCC
PRFDQIHTIDQVFQHNLREIEHFFAIYKELEGKRTVMQGWKGPREARDVIRRSRERYLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHC
HPELQLDPEAS
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]