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The map label for this gene is blaR1 [H]

Identifier: 116624565

GI number: 116624565

Start: 6882783

End: 6884984

Strand: Direct

Name: blaR1 [H]

Synonym: Acid_5489

Alternate gene names: 116624565

Gene position: 6882783-6884984 (Clockwise)

Preceding gene: 116624564

Following gene: 116624568

Centisome position: 69.07

GC content: 64.44

Gene sequence:

>2202_bases
ATGACACCTCTACTGGAAGCTTTTAGCGCGGCGCTGCTGCACTTCGCGTGGCAGGGCTGCCTGATTATGGCCCTACTATG
GGTGACGCTGTTCGTCTTACGGGCAGGCTCCGCAAAGGCTCGCTACACCTCGGGCTGCGCGGCGCTCGCGCTCATAGCTC
TCGCTCCCCTGCTCACCACGTTCGCGCTCTATCGAGCGCCGGCATCCGTGGGCCTTGCGACTGCGCCGTTCAACGTGCTG
CCCAGCGGGATCGCGCATTCTTCATCGGCTCCCCGCACGTCGGTCCTGGCTGCGATTCAGTCCTGGGCTCTGCCCGCCTG
GGCCTTCGGGGTGCTCCTCTTTTCATTGCGGATGGTGTGGGGATGTGCGCAAGTGGCCGCCCTGAAGCGTCGCGGCCAAC
CGGTAGGGGACGAGGTGCTTTCGCTGGTAGTACGCCTCCGCCAAAGAATGGGCATCCACAGGCAGGCCCGCGTTTTGGTC
TCCGAGTGGTCCGGCGGACCGAGCCTTGTCGGCTGGCTGCGGCCCGTGATCCTGCTCCCGGCGGCAGCTCTCGCGGGTCT
CACGCCGCAACAACTCGAAGCCGTGCTGGCGCATGAGCTCGCGCACATCCGGCGCCACGACTACCTGGTCAATTGGATGC
AAATGCTGGTGGAGACGCTGCTGTTCTATCACCCGGCCGTCTGGTGGATTTCATCGCGCGTCCGCCACGAGCGCGAGCTT
TGCTGCGACGATCTGGCGGTGAGCGCGTGCGAAGGCGCCCTCTGCTATGCCCGCGCGCTGACCATGCTCGAAAAGCTGCG
CGTCCATGCTCCCGTGACGGCTCTGGGCAGCACCGATGGGGCGCTGCTCTACCGCATTCAGAGAATCGCCGGAGTCGCGA
ATCACGAGTACGGACCTTCCCGGGCGCCGGTGGTCGTCACGTTATCCCTTGCAGTCGCCGGCCTGGTATTCAGCGTGAAT
TGGGCGCGCGCGCAGAGCCAACCTGCGAACGACTATATGTCGCAGGGCGACACCCTCCTGCGAAGCGGCGTTAATGAACT
CGCGCTGCAGAAATACATGGAGGGTGTCGCGGCAGACCCTGCCCACCGCGCGACACTTCAGAAGCGTTGTATCGAAGCCT
ACATGCGGATGGGCAGGAAGGCCGAAGCCGCCGACGTGAACGCGCAGCTACTGAAGGAACATCCCCACGACACGGACGGG
TTGGCTTTCGGCGCAACCATTCTTCTCGATCAGGGCAACGTCGCCGCGGCCATTGCGCAATTGCAACAGGTGCTGGAGCG
CGCGCCCGACAATCCCGTGGCTCACTTCGATCTGGGCCGCGCCTACATTGCGCAGGGCGATCTCATGGCCGCGCGCCGGG
AAATTGAGGAGGCAATCGCGCTCCGGCCTGATTTCACCCGCGCACGGCAGGCTCTGGAACGCCTGTCGCCCGGCGCCGGC
GGAGACGCGAACGAAGATGAGTTGGCGCGTCTGCAATCCGAGTCCGCGAAAGCTCCCGAGCGTCTCGACCTGCTTCAGTC
GCTGGGCACCGCCGCCGTACGGGCGGGCAAGTTTGACCTCGCGATTTATGCCTATCAGAAGTTGTTGGACCGTACCCGCG
AGCCCTCCGAGCTACGCGGCGAGCTCTATCTCAAACTCGGAGACGCCTACGTCCGCAAGGGCGATTCCGCGGCCGCGCTC
GATGCCATGCAAAAGGCGCGCGAGTTGGCGCCCGGCAACCGGCTCGTGCTCGGACCCCTGCTGACGCTGCTCGATGGGGC
CGGCCGGCACGCCGAGGCCAACCAACTGCGCGCCGGGATCGAAACCGTGGCGGCGCATCAAGCTGAGCTGACGACGCAGT
TCCTGAACGACGAAGTTGCTGCCGCCGAACAACGGCTCGCCAAGCTTCGACTCCAGCCGTCGGCAGACGCCGAGAAAATC
CGGCAGGCCGAATTCCAGTTGTTCGAACTCAAGCGCAAGGCATCAGCCTCGCCTCAACTCCAGCCGACCGGACGCGTGCT
CGAATCCATCTTCGTTGCCGGTATGACCGAAGCAATGAGGAAGCAATTCCGCGTGCCGGTACACGTGGGCGACACTCTGA
CACAGGACACCATAGGCGCCACATACTCTGCGGTGAAGCTCTTCGACAGCTCGCTCGAGTTACGCTTCCTCGTCCAGGCG
AACGGCAGGGTCAGGTTGTTGATCGGCAGGCAGCCGAACTAG

Upstream 100 bases:

>100_bases
GTGAAAGCGCTCGTGCTGCAGGCGCTGGCCACGAAGAAGTCGTCGCCGGAGGAATTGGCAGCCCTCGAAAAACTCCTGGA
TCGCATGGAGGACAGGAAAA

Downstream 100 bases:

>100_bases
CTACTGCCCAGCCGGAACGCGCGGACCCACGGCGCTCATGTCGATCGGTTGGAAGCCGAGCTTCAATGCCGGCGAGTTCG
GCCTCAGGCGGAAATCGAAG

Product: peptidase M56, BlaR1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MTPLLEAFSAALLHFAWQGCLIMALLWVTLFVLRAGSAKARYTSGCAALALIALAPLLTTFALYRAPASVGLATAPFNVL
PSGIAHSSSAPRTSVLAAIQSWALPAWAFGVLLFSLRMVWGCAQVAALKRRGQPVGDEVLSLVVRLRQRMGIHRQARVLV
SEWSGGPSLVGWLRPVILLPAAALAGLTPQQLEAVLAHELAHIRRHDYLVNWMQMLVETLLFYHPAVWWISSRVRHEREL
CCDDLAVSACEGALCYARALTMLEKLRVHAPVTALGSTDGALLYRIQRIAGVANHEYGPSRAPVVVTLSLAVAGLVFSVN
WARAQSQPANDYMSQGDTLLRSGVNELALQKYMEGVAADPAHRATLQKRCIEAYMRMGRKAEAADVNAQLLKEHPHDTDG
LAFGATILLDQGNVAAAIAQLQQVLERAPDNPVAHFDLGRAYIAQGDLMAARREIEEAIALRPDFTRARQALERLSPGAG
GDANEDELARLQSESAKAPERLDLLQSLGTAAVRAGKFDLAIYAYQKLLDRTREPSELRGELYLKLGDAYVRKGDSAAAL
DAMQKARELAPGNRLVLGPLLTLLDGAGRHAEANQLRAGIETVAAHQAELTTQFLNDEVAAAEQRLAKLRLQPSADAEKI
RQAEFQLFELKRKASASPQLQPTGRVLESIFVAGMTEAMRKQFRVPVHVGDTLTQDTIGATYSAVKLFDSSLELRFLVQA
NGRVRLLIGRQPN

Sequences:

>Translated_733_residues
MTPLLEAFSAALLHFAWQGCLIMALLWVTLFVLRAGSAKARYTSGCAALALIALAPLLTTFALYRAPASVGLATAPFNVL
PSGIAHSSSAPRTSVLAAIQSWALPAWAFGVLLFSLRMVWGCAQVAALKRRGQPVGDEVLSLVVRLRQRMGIHRQARVLV
SEWSGGPSLVGWLRPVILLPAAALAGLTPQQLEAVLAHELAHIRRHDYLVNWMQMLVETLLFYHPAVWWISSRVRHEREL
CCDDLAVSACEGALCYARALTMLEKLRVHAPVTALGSTDGALLYRIQRIAGVANHEYGPSRAPVVVTLSLAVAGLVFSVN
WARAQSQPANDYMSQGDTLLRSGVNELALQKYMEGVAADPAHRATLQKRCIEAYMRMGRKAEAADVNAQLLKEHPHDTDG
LAFGATILLDQGNVAAAIAQLQQVLERAPDNPVAHFDLGRAYIAQGDLMAARREIEEAIALRPDFTRARQALERLSPGAG
GDANEDELARLQSESAKAPERLDLLQSLGTAAVRAGKFDLAIYAYQKLLDRTREPSELRGELYLKLGDAYVRKGDSAAAL
DAMQKARELAPGNRLVLGPLLTLLDGAGRHAEANQLRAGIETVAAHQAELTTQFLNDEVAAAEQRLAKLRLQPSADAEKI
RQAEFQLFELKRKASASPQLQPTGRVLESIFVAGMTEAMRKQFRVPVHVGDTLTQDTIGATYSAVKLFDSSLELRFLVQA
NGRVRLLIGRQPN
>Mature_732_residues
TPLLEAFSAALLHFAWQGCLIMALLWVTLFVLRAGSAKARYTSGCAALALIALAPLLTTFALYRAPASVGLATAPFNVLP
SGIAHSSSAPRTSVLAAIQSWALPAWAFGVLLFSLRMVWGCAQVAALKRRGQPVGDEVLSLVVRLRQRMGIHRQARVLVS
EWSGGPSLVGWLRPVILLPAAALAGLTPQQLEAVLAHELAHIRRHDYLVNWMQMLVETLLFYHPAVWWISSRVRHERELC
CDDLAVSACEGALCYARALTMLEKLRVHAPVTALGSTDGALLYRIQRIAGVANHEYGPSRAPVVVTLSLAVAGLVFSVNW
ARAQSQPANDYMSQGDTLLRSGVNELALQKYMEGVAADPAHRATLQKRCIEAYMRMGRKAEAADVNAQLLKEHPHDTDGL
AFGATILLDQGNVAAAIAQLQQVLERAPDNPVAHFDLGRAYIAQGDLMAARREIEEAIALRPDFTRARQALERLSPGAGG
DANEDELARLQSESAKAPERLDLLQSLGTAAVRAGKFDLAIYAYQKLLDRTREPSELRGELYLKLGDAYVRKGDSAAALD
AMQKARELAPGNRLVLGPLLTLLDGAGRHAEANQLRAGIETVAAHQAELTTQFLNDEVAAAEQRLAKLRLQPSADAEKIR
QAEFQLFELKRKASASPQLQPTGRVLESIFVAGMTEAMRKQFRVPVHVGDTLTQDTIGATYSAVKLFDSSLELRFLVQAN
GRVRLLIGRQPN

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 79781; Mature: 79650

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLLEAFSAALLHFAWQGCLIMALLWVTLFVLRAGSAKARYTSGCAALALIALAPLLTT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FALYRAPASVGLATAPFNVLPSGIAHSSSAPRTSVLAAIQSWALPAWAFGVLLFSLRMVW
HHHHHCCHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GCAQVAALKRRGQPVGDEVLSLVVRLRQRMGIHRQARVLVSEWSGGPSLVGWLRPVILLP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AAALAGLTPQQLEAVLAHELAHIRRHDYLVNWMQMLVETLLFYHPAVWWISSRVRHEREL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CCDDLAVSACEGALCYARALTMLEKLRVHAPVTALGSTDGALLYRIQRIAGVANHEYGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
RAPVVVTLSLAVAGLVFSVNWARAQSQPANDYMSQGDTLLRSGVNELALQKYMEGVAADP
CCCEEEEHHHHHHHHHHHCHHHHHCCCCCHHHHHCCHHHHHHCHHHHHHHHHHHHHCCCH
AHRATLQKRCIEAYMRMGRKAEAADVNAQLLKEHPHDTDGLAFGATILLDQGNVAAAIAQ
HHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCCCEECEEEEEECCCHHHHHHH
LQQVLERAPDNPVAHFDLGRAYIAQGDLMAARREIEEAIALRPDFTRARQALERLSPGAG
HHHHHHHCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GDANEDELARLQSESAKAPERLDLLQSLGTAAVRAGKFDLAIYAYQKLLDRTREPSELRG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCC
ELYLKLGDAYVRKGDSAAALDAMQKARELAPGNRLVLGPLLTLLDGAGRHAEANQLRAGI
HHEEEECHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHH
ETVAAHQAELTTQFLNDEVAAAEQRLAKLRLQPSADAEKIRQAEFQLFELKRKASASPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
QPTGRVLESIFVAGMTEAMRKQFRVPVHVGDTLTQDTIGATYSAVKLFDSSLELRFLVQA
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NGRVRLLIGRQPN
CCEEEEEECCCCC
>Mature Secondary Structure 
TPLLEAFSAALLHFAWQGCLIMALLWVTLFVLRAGSAKARYTSGCAALALIALAPLLTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FALYRAPASVGLATAPFNVLPSGIAHSSSAPRTSVLAAIQSWALPAWAFGVLLFSLRMVW
HHHHHCCHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GCAQVAALKRRGQPVGDEVLSLVVRLRQRMGIHRQARVLVSEWSGGPSLVGWLRPVILLP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AAALAGLTPQQLEAVLAHELAHIRRHDYLVNWMQMLVETLLFYHPAVWWISSRVRHEREL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CCDDLAVSACEGALCYARALTMLEKLRVHAPVTALGSTDGALLYRIQRIAGVANHEYGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
RAPVVVTLSLAVAGLVFSVNWARAQSQPANDYMSQGDTLLRSGVNELALQKYMEGVAADP
CCCEEEEHHHHHHHHHHHCHHHHHCCCCCHHHHHCCHHHHHHCHHHHHHHHHHHHHCCCH
AHRATLQKRCIEAYMRMGRKAEAADVNAQLLKEHPHDTDGLAFGATILLDQGNVAAAIAQ
HHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCCCEECEEEEEECCCHHHHHHH
LQQVLERAPDNPVAHFDLGRAYIAQGDLMAARREIEEAIALRPDFTRARQALERLSPGAG
HHHHHHHCCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GDANEDELARLQSESAKAPERLDLLQSLGTAAVRAGKFDLAIYAYQKLLDRTREPSELRG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCC
ELYLKLGDAYVRKGDSAAALDAMQKARELAPGNRLVLGPLLTLLDGAGRHAEANQLRAGI
HHEEEECHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHH
ETVAAHQAELTTQFLNDEVAAAEQRLAKLRLQPSADAEKIRQAEFQLFELKRKASASPQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
QPTGRVLESIFVAGMTEAMRKQFRVPVHVGDTLTQDTIGATYSAVKLFDSSLELRFLVQA
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NGRVRLLIGRQPN
CCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]