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The map label for this gene is yfdZ [H]

Identifier: 116624456

GI number: 116624456

Start: 6737560

End: 6738753

Strand: Direct

Name: yfdZ [H]

Synonym: Acid_5378

Alternate gene names: 116624456

Gene position: 6737560-6738753 (Clockwise)

Preceding gene: 116624455

Following gene: 116624457

Centisome position: 67.61

GC content: 61.22

Gene sequence:

>1194_bases
ATGCCCGATAGTTCCGACGAGTTCTACCGCATTCAGAAACTGCCTCCGTACGTCTTCGCCGTTATCAACGAAATGCGCGC
CAAGGCGCGCGCCGCGCAGATCGATGTGATCGACCTGGGAATGGGGAATCCCGATGGCGCCACCCCGCGCGTGATCGTCA
ATAAAATGATCGAAGCCACGCGCAACCCGCGCAATCATCGGTATTCTCAGTCGCGCGGCATCCCCAAATTACGCGAAGAA
ATTACCCGCCGCTATCTCGCGAACTACGGCGTCGAACTCGATCCCGATAAGGAAGCCATCGTCACCATCGGCGCCAAGGA
CGCGCTCGCCCACCTGCTGTTCGCCACCGTCGGCCCTGGCGACACGGTCGTCTCTCCCAACCCCGCCTATCCCATTCATC
AGTACGGCGTGCTCATGGCCGAAGGCCACGCCTGCATGCTCCCCATGCCCGATGCCGCCACCTTCCTCGAGCGCCTCAAA
GAGCTTTACCGCAACAACTCGAAGAAGCCCAAGCTGCTGCTCATCTCTTTCCCGCACAACCCCACCACCACCTGCGTGGA
CTTGGATTTCTTCCGCGAGATCGTCGCCCTGGCGCGCGAACACGGCACACTCATCGTTCACGATTTCGCCTACGCCGACC
TCGGCTTCGATGGCTACCAGCCGCCCAGCATTCTGCAGGTCGAAGGCGCCAAGGATGTCGCCGTGGAGATTTTCTCCCTC
TCCAAGAGTTACAACATGGCCGGCTGGCGCGTAGGTTTCTGCGTCGGCAACCAGAAGATGATCTCCGCTCTCGCGCGCAT
AAAGAGCTACTTGGATTACGGCGTGTTCCAGCCCATTCAAATCGCCAGCATCATCGCCCTCCGCGAATGCGAGGAGGATA
CGAAGAAAATCTGCGCAGTCTATCAGAAACGCCGCGACGTCCTCGTCAATGGCTTGAAGCGCGCCGGATGGCCCGTCGAA
AAGCCGCGCGGTTCCATGTTCCTGTGGGCGCCCGTCCCCGAGAAATACCGCGCCGCCGGCTCTCTGGAATTCTGCAAACT
GCTGCTGGAGAAAGCGCAGGTCGCGGTCTCCCCCGGCATCGGCTTCGGCCCGCTTGGCGAAGGCCACGTCCGCTTCGCCC
TCGTCGAAAACGAGCAGCGCATCCGCCAGGCCACCCGCGCCATCGGCCAGTTCTTCAAGTCAGACGCCCAGTAG

Upstream 100 bases:

>100_bases
CTGATCACCTGCTATCCATTCTTCTTCGTGGGCTCGGCCCCCAAACGCTTCGTCGTCCAGGCTCGCCTCGCCGGCCAGGT
CGAAATAAGTAAAATGAGGA

Downstream 100 bases:

>100_bases
TACAGCTCTCCGGCCGTAGTGCTGTAGAATTTGTGGGGCAGACCCCAATAGGCGTTAACTTACGCTCTCAGCGGATCTGG
TCCCGGACTGCCGGACCGAT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPDSSDEFYRIQKLPPYVFAVINEMRAKARAAQIDVIDLGMGNPDGATPRVIVNKMIEATRNPRNHRYSQSRGIPKLREE
ITRRYLANYGVELDPDKEAIVTIGAKDALAHLLFATVGPGDTVVSPNPAYPIHQYGVLMAEGHACMLPMPDAATFLERLK
ELYRNNSKKPKLLLISFPHNPTTTCVDLDFFREIVALAREHGTLIVHDFAYADLGFDGYQPPSILQVEGAKDVAVEIFSL
SKSYNMAGWRVGFCVGNQKMISALARIKSYLDYGVFQPIQIASIIALRECEEDTKKICAVYQKRRDVLVNGLKRAGWPVE
KPRGSMFLWAPVPEKYRAAGSLEFCKLLLEKAQVAVSPGIGFGPLGEGHVRFALVENEQRIRQATRAIGQFFKSDAQ

Sequences:

>Translated_397_residues
MPDSSDEFYRIQKLPPYVFAVINEMRAKARAAQIDVIDLGMGNPDGATPRVIVNKMIEATRNPRNHRYSQSRGIPKLREE
ITRRYLANYGVELDPDKEAIVTIGAKDALAHLLFATVGPGDTVVSPNPAYPIHQYGVLMAEGHACMLPMPDAATFLERLK
ELYRNNSKKPKLLLISFPHNPTTTCVDLDFFREIVALAREHGTLIVHDFAYADLGFDGYQPPSILQVEGAKDVAVEIFSL
SKSYNMAGWRVGFCVGNQKMISALARIKSYLDYGVFQPIQIASIIALRECEEDTKKICAVYQKRRDVLVNGLKRAGWPVE
KPRGSMFLWAPVPEKYRAAGSLEFCKLLLEKAQVAVSPGIGFGPLGEGHVRFALVENEQRIRQATRAIGQFFKSDAQ
>Mature_396_residues
PDSSDEFYRIQKLPPYVFAVINEMRAKARAAQIDVIDLGMGNPDGATPRVIVNKMIEATRNPRNHRYSQSRGIPKLREEI
TRRYLANYGVELDPDKEAIVTIGAKDALAHLLFATVGPGDTVVSPNPAYPIHQYGVLMAEGHACMLPMPDAATFLERLKE
LYRNNSKKPKLLLISFPHNPTTTCVDLDFFREIVALAREHGTLIVHDFAYADLGFDGYQPPSILQVEGAKDVAVEIFSLS
KSYNMAGWRVGFCVGNQKMISALARIKSYLDYGVFQPIQIASIIALRECEEDTKKICAVYQKRRDVLVNGLKRAGWPVEK
PRGSMFLWAPVPEKYRAAGSLEFCKLLLEKAQVAVSPGIGFGPLGEGHVRFALVENEQRIRQATRAIGQFFKSDAQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=22.9974160206718, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=22.9974160206718, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI95147551, Length=388, Percent_Identity=23.1958762886598, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI169881279, Length=388, Percent_Identity=23.1958762886598, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=54.2713567839196, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=26.5625, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788627, Length=376, Percent_Identity=22.8723404255319, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=406, Percent_Identity=24.384236453202, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=271, Percent_Identity=25.4612546125461, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=271, Percent_Identity=25.4612546125461, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=326, Percent_Identity=22.3926380368098, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573069, Length=397, Percent_Identity=23.6775818639798, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646114, Length=397, Percent_Identity=23.6775818639798, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573067, Length=397, Percent_Identity=23.6775818639798, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573065, Length=397, Percent_Identity=23.6775818639798, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44299; Mature: 44168

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSSDEFYRIQKLPPYVFAVINEMRAKARAAQIDVIDLGMGNPDGATPRVIVNKMIEAT
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHH
RNPRNHRYSQSRGIPKLREEITRRYLANYGVELDPDKEAIVTIGAKDALAHLLFATVGPG
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHCCCCC
DTVVSPNPAYPIHQYGVLMAEGHACMLPMPDAATFLERLKELYRNNSKKPKLLLISFPHN
CCEECCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PTTTCVDLDFFREIVALAREHGTLIVHDFAYADLGFDGYQPPSILQVEGAKDVAVEIFSL
CCCEEEEHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHH
SKSYNMAGWRVGFCVGNQKMISALARIKSYLDYGVFQPIQIASIIALRECEEDTKKICAV
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQKRRDVLVNGLKRAGWPVEKPRGSMFLWAPVPEKYRAAGSLEFCKLLLEKAQVAVSPGI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHEECCCC
GFGPLGEGHVRFALVENEQRIRQATRAIGQFFKSDAQ
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDSSDEFYRIQKLPPYVFAVINEMRAKARAAQIDVIDLGMGNPDGATPRVIVNKMIEAT
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHH
RNPRNHRYSQSRGIPKLREEITRRYLANYGVELDPDKEAIVTIGAKDALAHLLFATVGPG
CCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHCCCCC
DTVVSPNPAYPIHQYGVLMAEGHACMLPMPDAATFLERLKELYRNNSKKPKLLLISFPHN
CCEECCCCCCCHHHCCEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PTTTCVDLDFFREIVALAREHGTLIVHDFAYADLGFDGYQPPSILQVEGAKDVAVEIFSL
CCCEEEEHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHH
SKSYNMAGWRVGFCVGNQKMISALARIKSYLDYGVFQPIQIASIIALRECEEDTKKICAV
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQKRRDVLVNGLKRAGWPVEKPRGSMFLWAPVPEKYRAAGSLEFCKLLLEKAQVAVSPGI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHEECCCC
GFGPLGEGHVRFALVENEQRIRQATRAIGQFFKSDAQ
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]