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The map label for this gene is uppP

Identifier: 116624148

GI number: 116624148

Start: 6396865

End: 6397692

Strand: Direct

Name: uppP

Synonym: Acid_5064

Alternate gene names: 116624148

Gene position: 6396865-6397692 (Clockwise)

Preceding gene: 116624145

Following gene: 116624149

Centisome position: 64.19

GC content: 61.47

Gene sequence:

>828_bases
ATGCCCATTCTGCAAGTGATCGTCCTGGCGGTGGTCCAGGGCCTGACTGAATTTCTGCCGATTTCGAGCACGGCTCATTT
GTACCTGACATCGTGGCTGCTCGGCTGGCAGATCGAAGGGCTGGATTTCGATATCGCGCTCCACATCGGCACACTTTTGG
CCGTGCTGATCTTCTTCGCGCGCGACTGGCTGCAGATCATCGCGCAGGGGTTCGGCATCCGCCGGGAAGGCGACCGTGAG
CTCAACCACAATCACATGCTGCTCTGGCTGCTGTTGATCGGCACGGTGCCGGTGGGAATCGCGGGCCTCTTGTTCAATAA
GCAGGCGGAAGGTGCGTGGCGGAATCCCTTCGTAATGGGTTTCATGCTGATCGTCGTGGGCGTGCTGATGTGGATCGCGG
AGAACGCCGGCAGACAGCAGCGAGATCTTTCCTCGCTGGACCTGGCCGACACGCTCGCGATCGGCACGGCGCAGGCGCTG
GCGGTGGTGCCCGGCACTTCGCGCAGCGGCGTCACGATCACAGCGGGGTTGTTCCGGAGTTTAACGCGCGAATCGGCGGC
GCGCTTTTCCTTCCTGCTCTCCACTCCGGCCATCGGGGCGGCGGCGGCGAAGGCGATTTGGGACATGCACAAGAAGGGCG
GCGGCCTGCACGGCATGCTGCATGCGGATTTTCTGGTGGGTGTGGCAGTCAGCGCGATTACCGGCTGCATCGTGATCGCC
TGGTTTCTGCATTATCTGCGTCGCAACGGCCTGAGGCCGTTTGTGTACTACCGGATTCTTTTTGGCATAATAGTGCTTGC
TCTGGCTTTCATCCGCCGGCCAGCGTGA

Upstream 100 bases:

>100_bases
AGACGCCGGTGAGAAGAAAACTAGCTTGATCGGGTTGCATTCGACCAGAATAGCGCGCCGGACTTGACACTGCGGTGACA
TTCGCTCACGCTGATCCTTT

Downstream 100 bases:

>100_bases
TGAAGCTACTATCACCGACTCAGCACAGAAGGCTGAATGAGATCGTCGGGTTCCTGCTGCTTTCGCTGGGCCTGGTGCTG
CTCTTGAGCCTGGTGTCGTA

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFARDWLQIIAQGFGIRREGDRE
LNHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMGFMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQAL
AVVPGTSRSGVTITAGLFRSLTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIA
WFLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA

Sequences:

>Translated_275_residues
MPILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFARDWLQIIAQGFGIRREGDRE
LNHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMGFMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQAL
AVVPGTSRSGVTITAGLFRSLTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIA
WFLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA
>Mature_274_residues
PILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFARDWLQIIAQGFGIRREGDREL
NHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMGFMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQALA
VVPGTSRSGVTITAGLFRSLTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIAW
FLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=259, Percent_Identity=33.5907335907336, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SOLUE (Q01WE6)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826304.1
- STRING:   Q01WE6
- GeneID:   4426707
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5064
- NMPDR:   fig|234267.9.peg.4809
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   DISIAQG
- PhylomeDB:   Q01WE6
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30095; Mature: 29964

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1baf2a50)-; HASH(0x1cac8e60)-; HASH(0x1cad9c04)-; HASH(0x1cee5d28)-; HASH(0x1cac8c44)-; HASH(0x1c7ba720)-; HASH(0x1c956cf4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFA
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
RDWLQIIAQGFGIRREGDRELNHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMG
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQALAVVPGTSRSGVTITAGLFRS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHH
LTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WFLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
PILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
RDWLQIIAQGFGIRREGDRELNHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMG
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQALAVVPGTSRSGVTITAGLFRS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHH
LTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WFLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA