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The map label for this gene is glnS [H]

Identifier: 116624097

GI number: 116624097

Start: 6327121

End: 6328827

Strand: Direct

Name: glnS [H]

Synonym: Acid_5012

Alternate gene names: 116624097

Gene position: 6327121-6328827 (Clockwise)

Preceding gene: 116624096

Following gene: 116624098

Centisome position: 63.49

GC content: 60.87

Gene sequence:

>1707_bases
ATGACCACTGCAAACCCAGAGCCGGCAGCCGGCCCTTCGAATTTCATTCGTGACATCATCCTGGATGACCTGAACACAAA
TAAGTACCAGGGGCGCGTGCACACGCGGTTTCCTCCGGAGCCGAACGGGTACCTGCACATCGGCCACGCCAAATCGATCT
GCCTGAATTTCGGACTGGCGGCGGAGTTCGGCGGCAAGACGAATTTGCGTTTCGACGACACCAATCCCAGCAAAGAAGAG
ACGGAGTACGTCGATTCGATTATCGACTCTGTGCGCTGGCTGGGCTTCGATTGGGAAGACCGGCTTTTCTACGCGTCGGA
TTATTTCCATCAGTTGTACGATTGGGCGCTGCAGATGATCCGCGAGGGCAAGGCCTTCGTGTGCGACCTCACCGCCGACG
AAATCCGCCAGTACCGCGGCACGCCCACGGAACCGGGCAAGGAGAGCCCGTACCGCAATCGCAGCGTGGAGGAGAACCTG
GACCTGTTCGCGCGCATGAAAGCCGGCGAGTTTCCCGATGGCAGCCGTACCCTGCGCGCCAAGATCGACATGGCGTCGCC
GAATTTCAACCTGCGCGACCCGATCATGTACCGCATCGTGCACGCCGAGCATCATCGCACCGGCAACGAGTGGTGCATCT
ATCCGATGTACGACTACGCGCACGGGCAGAGTGATTCCATCGAACGCATCACTCACTCCATCTGCACGCTGGAATTCGAA
GACCACCGGCCGCTCTACGATTGGTACATCGAGGCGCTGGGAATCTACCATCCGCAGCAGATCGAATTCGACCGGCTGAA
TATCACCTACACGCTGCTGAGCAAGCGGAAACTGCTGCAGTTGGTGCAGGACGGGCACGTAAGCGGGTGGGACGATCCGC
GCATGCCCACGCTTGTCGGCATCCGGCGGCGCGGCTACACGCCCGAGGCGATGCGCAATTTCTGCGCGGCGATTGGGCTT
TCCAAGACCAACGGCATCATCGAACTCGGAAGGCTGGAATATTTCGTCCGCGAAGATTTGAACAAGCGCGCGCAGCGCGT
GATGGCGGTGCTGCGGCCCCTGAAGGTAGTGATCGATAACTACCCGGAGGGCCAGGTAGAAGAGATGGAGGCTGTGAACA
ATCCCGAGGATGCGTCGGCCGGGACGCGTAAGGTACCGTTCTCGCGGGAACTCTACATCGAGCAGGACGATTTCCGCGAA
GACCCACCGAAGGAATTCTTCCGGCTGGCCCCCGGCCGCGAAGTGCGGCTGCGCTACGGCTACTTCATCAAGTGCACGGG
CGTGGTGAAGAATGCGGCCGGCGAGATCACGGAAGTTCACTGCACCTACGACCCGGAGACGCGCGGCGGCAACGCACCGG
ACGGGCGCAAGGTGAAGGCGACCATCCATTGGGTGTCGGCGGCTCAGGCCGTGTCCGGCGAGGTGCGGATGTACGACACG
CTGTTCCTCAAGGAAGATCCGAACCAGGTGGCAGAGGGGCAGGACTTCACGGCGAATCTGAATCCGAAGTCGCTCGAGAT
CATTCGCGATGCGAAGCTGGAGCCGAGCCTGGCTAACGCGGCGCCGGGTACGCGACTGCAATTCGAGCGCCTCGGCTACT
TCTGCGTGGACAGCGATTCGACGCCCGGAAATCCGGTCTTCAACCGCACGGTAGCGTTGAAGGACACGTGGGCGAAGATC
GAGAAGCGGGGCACGCCGAAGAAATGA

Upstream 100 bases:

>100_bases
GCAAGACCGCGCCGCCCCTGTTCGGCACGCTGGAAGTTCTCGGCCGCGAGGCCTGCCTGGCGCGGATCGGCCAAGCCATC
GAAAAACTGTGAAAGAGATT

Downstream 100 bases:

>100_bases
TCATCCTCGGAATTGGCGGGCTGCTGGGCGACGCGGCCGCAGCCATATTGAAAGACGGCGAGTTGGTGGCCGCGGTAGAA
GAATCGAAGCTGGTGCGTCG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTTANPEPAAGPSNFIRDIILDDLNTNKYQGRVHTRFPPEPNGYLHIGHAKSICLNFGLAAEFGGKTNLRFDDTNPSKEE
TEYVDSIIDSVRWLGFDWEDRLFYASDYFHQLYDWALQMIREGKAFVCDLTADEIRQYRGTPTEPGKESPYRNRSVEENL
DLFARMKAGEFPDGSRTLRAKIDMASPNFNLRDPIMYRIVHAEHHRTGNEWCIYPMYDYAHGQSDSIERITHSICTLEFE
DHRPLYDWYIEALGIYHPQQIEFDRLNITYTLLSKRKLLQLVQDGHVSGWDDPRMPTLVGIRRRGYTPEAMRNFCAAIGL
SKTNGIIELGRLEYFVREDLNKRAQRVMAVLRPLKVVIDNYPEGQVEEMEAVNNPEDASAGTRKVPFSRELYIEQDDFRE
DPPKEFFRLAPGREVRLRYGYFIKCTGVVKNAAGEITEVHCTYDPETRGGNAPDGRKVKATIHWVSAAQAVSGEVRMYDT
LFLKEDPNQVAEGQDFTANLNPKSLEIIRDAKLEPSLANAAPGTRLQFERLGYFCVDSDSTPGNPVFNRTVALKDTWAKI
EKRGTPKK

Sequences:

>Translated_568_residues
MTTANPEPAAGPSNFIRDIILDDLNTNKYQGRVHTRFPPEPNGYLHIGHAKSICLNFGLAAEFGGKTNLRFDDTNPSKEE
TEYVDSIIDSVRWLGFDWEDRLFYASDYFHQLYDWALQMIREGKAFVCDLTADEIRQYRGTPTEPGKESPYRNRSVEENL
DLFARMKAGEFPDGSRTLRAKIDMASPNFNLRDPIMYRIVHAEHHRTGNEWCIYPMYDYAHGQSDSIERITHSICTLEFE
DHRPLYDWYIEALGIYHPQQIEFDRLNITYTLLSKRKLLQLVQDGHVSGWDDPRMPTLVGIRRRGYTPEAMRNFCAAIGL
SKTNGIIELGRLEYFVREDLNKRAQRVMAVLRPLKVVIDNYPEGQVEEMEAVNNPEDASAGTRKVPFSRELYIEQDDFRE
DPPKEFFRLAPGREVRLRYGYFIKCTGVVKNAAGEITEVHCTYDPETRGGNAPDGRKVKATIHWVSAAQAVSGEVRMYDT
LFLKEDPNQVAEGQDFTANLNPKSLEIIRDAKLEPSLANAAPGTRLQFERLGYFCVDSDSTPGNPVFNRTVALKDTWAKI
EKRGTPKK
>Mature_567_residues
TTANPEPAAGPSNFIRDIILDDLNTNKYQGRVHTRFPPEPNGYLHIGHAKSICLNFGLAAEFGGKTNLRFDDTNPSKEET
EYVDSIIDSVRWLGFDWEDRLFYASDYFHQLYDWALQMIREGKAFVCDLTADEIRQYRGTPTEPGKESPYRNRSVEENLD
LFARMKAGEFPDGSRTLRAKIDMASPNFNLRDPIMYRIVHAEHHRTGNEWCIYPMYDYAHGQSDSIERITHSICTLEFED
HRPLYDWYIEALGIYHPQQIEFDRLNITYTLLSKRKLLQLVQDGHVSGWDDPRMPTLVGIRRRGYTPEAMRNFCAAIGLS
KTNGIIELGRLEYFVREDLNKRAQRVMAVLRPLKVVIDNYPEGQVEEMEAVNNPEDASAGTRKVPFSRELYIEQDDFRED
PPKEFFRLAPGREVRLRYGYFIKCTGVVKNAAGEITEVHCTYDPETRGGNAPDGRKVKATIHWVSAAQAVSGEVRMYDTL
FLKEDPNQVAEGQDFTANLNPKSLEIIRDAKLEPSLANAAPGTRLQFERLGYFCVDSDSTPGNPVFNRTVALKDTWAKIE
KRGTPKK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=534, Percent_Identity=47.1910112359551, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI62241042, Length=517, Percent_Identity=35.3965183752418, Blast_Score=286, Evalue=4e-77,
Organism=Escherichia coli, GI1786895, Length=556, Percent_Identity=56.6546762589928, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=323, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17543332, Length=534, Percent_Identity=45.3183520599251, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17511007, Length=522, Percent_Identity=31.992337164751, Blast_Score=251, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6324742, Length=566, Percent_Identity=40.2826855123675, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321192, Length=518, Percent_Identity=35.7142857142857, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6324540, Length=305, Percent_Identity=24.5901639344262, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864488, Length=534, Percent_Identity=44.0074906367041, Blast_Score=443, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24649466, Length=517, Percent_Identity=33.8491295938104, Blast_Score=264, Evalue=1e-70,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65075; Mature: 64944

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANPEPAAGPSNFIRDIILDDLNTNKYQGRVHTRFPPEPNGYLHIGHAKSICLNFGLA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEECCHHEEHHCCCCC
AEFGGKTNLRFDDTNPSKEETEYVDSIIDSVRWLGFDWEDRLFYASDYFHQLYDWALQMI
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
REGKAFVCDLTADEIRQYRGTPTEPGKESPYRNRSVEENLDLFARMKAGEFPDGSRTLRA
HCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
KIDMASPNFNLRDPIMYRIVHAEHHRTGNEWCIYPMYDYAHGQSDSIERITHSICTLEFE
EEEECCCCCCCCCCHHEEEEEHHHCCCCCCEEEEECHHCCCCCCCHHHHHHHHHEEEEEC
DHRPLYDWYIEALGIYHPQQIEFDRLNITYTLLSKRKLLQLVQDGHVSGWDDPRMPTLVG
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
IRRRGYTPEAMRNFCAAIGLSKTNGIIELGRLEYFVREDLNKRAQRVMAVLRPLKVVIDN
HHHCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPEGQVEEMEAVNNPEDASAGTRKVPFSRELYIEQDDFREDPPKEFFRLAPGREVRLRYG
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEEEC
YFIKCTGVVKNAAGEITEVHCTYDPETRGGNAPDGRKVKATIHWVSAAQAVSGEVRMYDT
EEEEEECHHHCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHCCCEEEEEE
LFLKEDPNQVAEGQDFTANLNPKSLEIIRDAKLEPSLANAAPGTRLQFERLGYFCVDSDS
EEEECCCHHHHCCCCEEECCCCCHHHHEECCCCCCCHHCCCCCCCEEHHHCCEEEEECCC
TPGNPVFNRTVALKDTWAKIEKRGTPKK
CCCCCCCCEEEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTANPEPAAGPSNFIRDIILDDLNTNKYQGRVHTRFPPEPNGYLHIGHAKSICLNFGLA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEECCHHEEHHCCCCC
AEFGGKTNLRFDDTNPSKEETEYVDSIIDSVRWLGFDWEDRLFYASDYFHQLYDWALQMI
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
REGKAFVCDLTADEIRQYRGTPTEPGKESPYRNRSVEENLDLFARMKAGEFPDGSRTLRA
HCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEE
KIDMASPNFNLRDPIMYRIVHAEHHRTGNEWCIYPMYDYAHGQSDSIERITHSICTLEFE
EEEECCCCCCCCCCHHEEEEEHHHCCCCCCEEEEECHHCCCCCCCHHHHHHHHHEEEEEC
DHRPLYDWYIEALGIYHPQQIEFDRLNITYTLLSKRKLLQLVQDGHVSGWDDPRMPTLVG
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
IRRRGYTPEAMRNFCAAIGLSKTNGIIELGRLEYFVREDLNKRAQRVMAVLRPLKVVIDN
HHHCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPEGQVEEMEAVNNPEDASAGTRKVPFSRELYIEQDDFREDPPKEFFRLAPGREVRLRYG
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEEEC
YFIKCTGVVKNAAGEITEVHCTYDPETRGGNAPDGRKVKATIHWVSAAQAVSGEVRMYDT
EEEEEECHHHCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHCCCEEEEEE
LFLKEDPNQVAEGQDFTANLNPKSLEIIRDAKLEPSLANAAPGTRLQFERLGYFCVDSDS
EEEECCCHHHHCCCCEEECCCCCHHHHEECCCCCCCHHCCCCCCCEEHHHCCEEEEECCC
TPGNPVFNRTVALKDTWAKIEKRGTPKK
CCCCCCCCEEEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]