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The map label for this gene is yhdP [H]

Identifier: 116624023

GI number: 116624023

Start: 6229094

End: 6230434

Strand: Reverse

Name: yhdP [H]

Synonym: Acid_4935

Alternate gene names: 116624023

Gene position: 6230434-6229094 (Counterclockwise)

Preceding gene: 116624027

Following gene: 116624022

Centisome position: 62.52

GC content: 61.37

Gene sequence:

>1341_bases
GTGACTGACTCGCCCATACGTCTTTTGCTCGTCATTCTGCTGATCGCGGTGAACGGGTTCTTCGCCGGCGCCGAAGTTGC
GTTGCTCTCCGTACGGCAATCGCGCTTGCGTCAAATGGCGGCGGAAGGCCACGCCGGGGCACATGCGGCGCTCAGCCTGC
TCTCCAATCCAGGAAGGTTGCTGTCGGTGACGCAGGTGGGCGTGACGCTGGCGAGCCTGGGCCTTGGATGGGCGGGCGAG
GACACGTTGTACCAGATTCTCTCGGCGATGTTTCATCCGCTGATGACGCCCGTGACCACGAAATTTCTCCACGGGCTCTG
CTTCTTCTTTTCGTTCCTGGTAATCAGTTATTTCCACGTGGTGTTCGGCGAAGTGGTGCCGAAAAACCTGGCGATCGCGA
AGGCGGCGCAGCTGGCCTCGTTGACGGCGCCGGCGCTGTTGCTTTTCTACCGCGCGACGGTGGCGTTCGTTGTCGTGATC
GAACGTTCGGCGGCGGCGATCACACACGCGCTGCACCTGAAGGGGGAAGGGCACGGCAACGTGCACACGTCGGAGGAGCT
GAAGCTCATCGTCTCCAGCAGCCGCGGATTGGGCTACCTGCCGGAGACGCAGGAGGACATGATCCATCGCGTGCTGGATC
TGGGTGCGTTATCGGTGCGCGAGATCATGATTCCGCGCAACGACATTGTTTCGATATCGACCGATGCGTCGCTCGATGAG
GTGCTGCACACGATGAATGAACAGCGCCATTCGCGGCTGCCGGTCTATGAGAAGACGCCCGAAAAGATAGTCGGCCTGCT
GCATTACAAGGACCTGCTGCCGGTGTGGGAAGAGCGGCGGCTGGCGATTCGCAGCAGCCGTCCCAGCCAGTCCTTCCGCG
TAAGCCGGCTGATGCGCCCGCTGATGTTTGTACCGGAGACGAAGGAAGTCTCGGCGATGCTGGACGAGTTCCGTCACGGC
CGCTCGCACATGGCGATGATTGTGGACGAGTTCGGCACGATCATCGGCATGGTGACGGTGGAAGACGTGTTGGAGCAGAT
CGTAGGGCAGATCGAGGATGAGCACGATGAGAGAGTCGAGCGGCAGGTAGAGGCGGATGATGTGGAGCTGGACGGGACCA
CCCGGATCCGCGATTTGGAGAGCGAATACGGGATCGAGATTCCGCCCGACGCGGGCTTCGAAACGCTGGCGGGTTTTCTG
CTGTTCAAGCTCGGCGAGATCCCGCGGGTGGAAAGTAGAGTAGAGTACGAAGGCCGCCGCTACACGGTGCTCGAAATGGA
GCGCAACCGGATCGCGCGCGTGCGCATAGAGAAACTGCAGCCCCACGACGGGGTAGGATGA

Upstream 100 bases:

>100_bases
TTGGAGGACGCCCACCTACGTAACGGAGTTAGTTGGTTACCTAATCTGACGATCCGCGGGCGATTTGGTTAGAAACTCCG
CTAGAATTATTTCGGAGCTT

Downstream 100 bases:

>100_bases
AAGTGAGCATGCTCGGACTGGAGCCCAAAGCGGCGCGGTACACATGGACGGCGGCGCTGGTGCTCCTGGCGTTGGAGCTG
GTGTATTTGCTGCGCTCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTDSPIRLLLVILLIAVNGFFAGAEVALLSVRQSRLRQMAAEGHAGAHAALSLLSNPGRLLSVTQVGVTLASLGLGWAGE
DTLYQILSAMFHPLMTPVTTKFLHGLCFFFSFLVISYFHVVFGEVVPKNLAIAKAAQLASLTAPALLLFYRATVAFVVVI
ERSAAAITHALHLKGEGHGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDASLDE
VLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRLMRPLMFVPETKEVSAMLDEFRHG
RSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDERVERQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFL
LFKLGEIPRVESRVEYEGRRYTVLEMERNRIARVRIEKLQPHDGVG

Sequences:

>Translated_446_residues
MTDSPIRLLLVILLIAVNGFFAGAEVALLSVRQSRLRQMAAEGHAGAHAALSLLSNPGRLLSVTQVGVTLASLGLGWAGE
DTLYQILSAMFHPLMTPVTTKFLHGLCFFFSFLVISYFHVVFGEVVPKNLAIAKAAQLASLTAPALLLFYRATVAFVVVI
ERSAAAITHALHLKGEGHGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDASLDE
VLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRLMRPLMFVPETKEVSAMLDEFRHG
RSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDERVERQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFL
LFKLGEIPRVESRVEYEGRRYTVLEMERNRIARVRIEKLQPHDGVG
>Mature_445_residues
TDSPIRLLLVILLIAVNGFFAGAEVALLSVRQSRLRQMAAEGHAGAHAALSLLSNPGRLLSVTQVGVTLASLGLGWAGED
TLYQILSAMFHPLMTPVTTKFLHGLCFFFSFLVISYFHVVFGEVVPKNLAIAKAAQLASLTAPALLLFYRATVAFVVVIE
RSAAAITHALHLKGEGHGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDASLDEV
LHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRLMRPLMFVPETKEVSAMLDEFRHGR
SHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDERVERQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLL
FKLGEIPRVESRVEYEGRRYTVLEMERNRIARVRIEKLQPHDGVG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=403, Percent_Identity=30.5210918114144, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI40068053, Length=406, Percent_Identity=23.6453201970443, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI40068055, Length=406, Percent_Identity=23.6453201970443, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI94681046, Length=289, Percent_Identity=25.9515570934256, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40068049, Length=163, Percent_Identity=30.6748466257669, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790664, Length=439, Percent_Identity=25.5125284738041, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI145693175, Length=431, Percent_Identity=25.754060324826, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786879, Length=263, Percent_Identity=33.4600760456274, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87082033, Length=350, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788119, Length=248, Percent_Identity=30.6451612903226, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324512, Length=364, Percent_Identity=24.7252747252747, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49788; Mature: 49657

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSPIRLLLVILLIAVNGFFAGAEVALLSVRQSRLRQMAAEGHAGAHAALSLLSNPGRL
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCE
LSVTQVGVTLASLGLGWAGEDTLYQILSAMFHPLMTPVTTKFLHGLCFFFSFLVISYFHV
EEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFGEVVPKNLAIAKAAQLASLTAPALLLFYRATVAFVVVIERSAAAITHALHLKGEGHGN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
VHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDASLDE
CCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCHHH
VLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRLMRP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
LMFVPETKEVSAMLDEFRHGRSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDERVE
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLLFKLGEIPRVESRVEYEGRR
HHHCCCCEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCE
YTVLEMERNRIARVRIEKLQPHDGVG
EEEEEECCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDSPIRLLLVILLIAVNGFFAGAEVALLSVRQSRLRQMAAEGHAGAHAALSLLSNPGRL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCE
LSVTQVGVTLASLGLGWAGEDTLYQILSAMFHPLMTPVTTKFLHGLCFFFSFLVISYFHV
EEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFGEVVPKNLAIAKAAQLASLTAPALLLFYRATVAFVVVIERSAAAITHALHLKGEGHGN
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
VHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDASLDE
CCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCHHH
VLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRLMRP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
LMFVPETKEVSAMLDEFRHGRSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDERVE
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLLFKLGEIPRVESRVEYEGRR
HHHCCCCEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCE
YTVLEMERNRIARVRIEKLQPHDGVG
EEEEEECCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]