Click here to switch to the map view.

The map label for this gene is quiA [H]

Identifier: 116624006

GI number: 116624006

Start: 6209883

End: 6211694

Strand: Direct

Name: quiA [H]

Synonym: Acid_4918

Alternate gene names: 116624006

Gene position: 6209883-6211694 (Clockwise)

Preceding gene: 116624005

Following gene: 116624008

Centisome position: 62.31

GC content: 64.13

Gene sequence:

>1812_bases
GTGCGGCTCGGACTTTGCTTCTTGGCGGCGGCGGCCGCAATTGGCCAGGATCATACGGCGTGGCGCGATTATTCGGGCGG
CGCGGATTCGGCACAATATTCGGCGCTGCGGCAGATCACGCGCGCCAATGTGAATCAGCTCGAGATCGCGTGGGTCTACC
CGACGGGGGACGATAAGAAGTACGCGTTCAATCCGCTGGTCGCCGACGGAATGATCTACGTGCTGGCGAAGAATAATTCG
GTGGTCGCGCTGGATGCGGCCACGGGAAAAGAGATCTGGTCGCACTCGCCGGACACGCCGACCACGATCATCACGAGCCG
CGGGTTGAACTACTGGGAGAGCAAGGACGGCAAGGACCGGCGGCTGTTATTTTGCGCGAACCACTCGCTGCGCGCGATTG
ATGCGCGCACCGGGAAGGCGATCGCAACGTTCGGCGTCAACGGCAGGGTGGACCTCAAGGAAGGGCTGGGGCGCGAGCCA
AAGAACATCAAGCTGGTGCAATCGACCACGCCGGGCCGGGTGTTCGAGAACCTGTTGATTCTGGGCTCGGCTACCAACGA
GGGCTACACTTCGGCGCCCGGCGACCTGCGGGCGTTCGACGTTCGTACGGGTGCGCAGGTCTGGGTCTTCCACACGATTC
CGCATCCCGGCGAGTTTGGTTACGAGACGTGGCCGAAGGACGCGTGGAAGAACGTGGGCGGCGCCAACGTGTGGGGGGAG
ATTTCCGTGGACGAGAAGCGGGGCATCGTCTACGCGCCCACGGCCAGCGCAAAGTACAACTTCTACGGCGCCGACCGCAA
GGGCGCCGACCTGTTCGCCGATTGCCTGCTGGCGCTGGACGCGCGCACGGGCAAGCGCATCTGGCATTTCCAGATGGTGC
ATCACGACATCTGGGATTACGACGATGCCACCGCGCCCAAGCTGCTGACGTTGAAGCACGAAGGCAAGATGGTGGACGCG
GTGGCGCAGGTCAGCAAACAGGGCTTCGTGTGGGTCTTCGATCGCGTGACCGGCGAACCGCTGTGGCCGATCGAAGAGCG
GGCGGTCCCCAAGACCGATATGCCGAATGAGCAGACCTGGCCAACGCAACCCTTCCCAACCAAGCCGCCGCCGTTCGCGC
GGCAGAAGTTTACGGCCGACGATTTGAGCCCGTTCCTTAGCGCGGCGGAGCGCGCGAAATTTCGCGACCAGATTTTGAGC
GCGCGGAATGAGGGACTGTTCACGCCGCCGGGGCTGCGCAATACCGTGCAGATGCCAGGGAATAATGGCGGCGCGAATTG
GGGCGGCGCGGCGATAGACCCGACGAAGGGCACTTTGTACGTGGTCTCGAAGGATCTGCCCGCGATGCTCAAGCTGGAGC
CCGCCGGACCCGACCGGTACACGAGCGGGTTCGGCTTTATGCTGGCGAGCGACGGGCTTTCACCGATCGCGCCGCCGTGG
TCGTCGCTGACGGCTTACGACTTGAATGAGGGGACGATTCGCTGGCAGATTCCGCTGGGCGACGTGCCGGAGCTGGCGGC
GAAGGGCTTCAAGAATACGGGCTCGCACTATCCGAAGGTCGGTCCGGTGGTGACGGCGGGCGGGCTGATTTTCACGGGCA
CTCGCGATCGCGAGGTTCGGGTGCTGGATGCGGAGACCGGGAAACTCATTTGGGAGAAGCAGGTGGACGCGGCGCTGGAA
GGGATGCCGGCGGTGTACCAGGTGGGCGGGCGCGAGTTCGTTGTGTTTTGCGCGTCGGCGCAGGTGGGGCTGATTCCGGC
GACGCAGGGGAAGGTGTCGGGGGCTTACGTGGCTTTCGCGTTGAAGAGGTGA

Upstream 100 bases:

>100_bases
CTATTTGCAGGACTACTTCGTGCATCATCTGCTGGGGGTGGAGCCGCCGGATTGGAATCACGTGAGCGTCAACGCGGAGA
GCACGGCGGGTGGCAACTGA

Downstream 100 bases:

>100_bases
GGGAGTGTAGATCGCTCCCTGACGGTCGCGGTTCGCGGTGAGAGCTCGTTGCGCTCCCTTACGGTCGCGCTTCGCGGGAC
CGGGTCAGAGTTCTTTGATG

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: NAD(P)-independent quinate dehydrogenase [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRLGLCFLAAAAAIGQDHTAWRDYSGGADSAQYSALRQITRANVNQLEIAWVYPTGDDKKYAFNPLVADGMIYVLAKNNS
VVALDAATGKEIWSHSPDTPTTIITSRGLNYWESKDGKDRRLLFCANHSLRAIDARTGKAIATFGVNGRVDLKEGLGREP
KNIKLVQSTTPGRVFENLLILGSATNEGYTSAPGDLRAFDVRTGAQVWVFHTIPHPGEFGYETWPKDAWKNVGGANVWGE
ISVDEKRGIVYAPTASAKYNFYGADRKGADLFADCLLALDARTGKRIWHFQMVHHDIWDYDDATAPKLLTLKHEGKMVDA
VAQVSKQGFVWVFDRVTGEPLWPIEERAVPKTDMPNEQTWPTQPFPTKPPPFARQKFTADDLSPFLSAAERAKFRDQILS
ARNEGLFTPPGLRNTVQMPGNNGGANWGGAAIDPTKGTLYVVSKDLPAMLKLEPAGPDRYTSGFGFMLASDGLSPIAPPW
SSLTAYDLNEGTIRWQIPLGDVPELAAKGFKNTGSHYPKVGPVVTAGGLIFTGTRDREVRVLDAETGKLIWEKQVDAALE
GMPAVYQVGGREFVVFCASAQVGLIPATQGKVSGAYVAFALKR

Sequences:

>Translated_603_residues
MRLGLCFLAAAAAIGQDHTAWRDYSGGADSAQYSALRQITRANVNQLEIAWVYPTGDDKKYAFNPLVADGMIYVLAKNNS
VVALDAATGKEIWSHSPDTPTTIITSRGLNYWESKDGKDRRLLFCANHSLRAIDARTGKAIATFGVNGRVDLKEGLGREP
KNIKLVQSTTPGRVFENLLILGSATNEGYTSAPGDLRAFDVRTGAQVWVFHTIPHPGEFGYETWPKDAWKNVGGANVWGE
ISVDEKRGIVYAPTASAKYNFYGADRKGADLFADCLLALDARTGKRIWHFQMVHHDIWDYDDATAPKLLTLKHEGKMVDA
VAQVSKQGFVWVFDRVTGEPLWPIEERAVPKTDMPNEQTWPTQPFPTKPPPFARQKFTADDLSPFLSAAERAKFRDQILS
ARNEGLFTPPGLRNTVQMPGNNGGANWGGAAIDPTKGTLYVVSKDLPAMLKLEPAGPDRYTSGFGFMLASDGLSPIAPPW
SSLTAYDLNEGTIRWQIPLGDVPELAAKGFKNTGSHYPKVGPVVTAGGLIFTGTRDREVRVLDAETGKLIWEKQVDAALE
GMPAVYQVGGREFVVFCASAQVGLIPATQGKVSGAYVAFALKR
>Mature_603_residues
MRLGLCFLAAAAAIGQDHTAWRDYSGGADSAQYSALRQITRANVNQLEIAWVYPTGDDKKYAFNPLVADGMIYVLAKNNS
VVALDAATGKEIWSHSPDTPTTIITSRGLNYWESKDGKDRRLLFCANHSLRAIDARTGKAIATFGVNGRVDLKEGLGREP
KNIKLVQSTTPGRVFENLLILGSATNEGYTSAPGDLRAFDVRTGAQVWVFHTIPHPGEFGYETWPKDAWKNVGGANVWGE
ISVDEKRGIVYAPTASAKYNFYGADRKGADLFADCLLALDARTGKRIWHFQMVHHDIWDYDDATAPKLLTLKHEGKMVDA
VAQVSKQGFVWVFDRVTGEPLWPIEERAVPKTDMPNEQTWPTQPFPTKPPPFARQKFTADDLSPFLSAAERAKFRDQILS
ARNEGLFTPPGLRNTVQMPGNNGGANWGGAAIDPTKGTLYVVSKDLPAMLKLEPAGPDRYTSGFGFMLASDGLSPIAPPW
SSLTAYDLNEGTIRWQIPLGDVPELAAKGFKNTGSHYPKVGPVVTAGGLIFTGTRDREVRVLDAETGKLIWEKQVDAALE
GMPAVYQVGGREFVVFCASAQVGLIPATQGKVSGAYVAFALKR

Specific function: Can act either on quinate or on shikimate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=646, Percent_Identity=28.0185758513932, Blast_Score=225, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.25 [H]

Molecular weight: Translated: 65808; Mature: 65808

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGLCFLAAAAAIGQDHTAWRDYSGGADSAQYSALRQITRANVNQLEIAWVYPTGDDKK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
YAFNPLVADGMIYVLAKNNSVVALDAATGKEIWSHSPDTPTTIITSRGLNYWESKDGKDR
EEECCEEECCEEEEEECCCCEEEEECCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
RLLFCANHSLRAIDARTGKAIATFGVNGRVDLKEGLGREPKNIKLVQSTTPGRVFENLLI
EEEEEECCCEEEEECCCCCEEEEECCCCEEEHHHCCCCCCCCEEEEECCCCHHHHCEEEE
LGSATNEGYTSAPGDLRAFDVRTGAQVWVFHTIPHPGEFGYETWPKDAWKNVGGANVWGE
EECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEE
ISVDEKRGIVYAPTASAKYNFYGADRKGADLFADCLLALDARTGKRIWHFQMVHHDIWDY
EEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCC
DDATAPKLLTLKHEGKMVDAVAQVSKQGFVWVFDRVTGEPLWPIEERAVPKTDMPNEQTW
CCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCC
PTQPFPTKPPPFARQKFTADDLSPFLSAAERAKFRDQILSARNEGLFTPPGLRNTVQMPG
CCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
NNGGANWGGAAIDPTKGTLYVVSKDLPAMLKLEPAGPDRYTSGFGFMLASDGLSPIAPPW
CCCCCCCCCCEECCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCC
SSLTAYDLNEGTIRWQIPLGDVPELAAKGFKNTGSHYPKVGPVVTAGGLIFTGTRDREVR
CCCEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEECCEEEECCCCCEEE
VLDAETGKLIWEKQVDAALEGMPAVYQVGGREFVVFCASAQVGLIPATQGKVSGAYVAFA
EEECCCCCEEEHHHHHHHHCCCCCEEECCCCEEEEEEECCCEEEEECCCCCCCCEEEEEE
LKR
ECC
>Mature Secondary Structure
MRLGLCFLAAAAAIGQDHTAWRDYSGGADSAQYSALRQITRANVNQLEIAWVYPTGDDKK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
YAFNPLVADGMIYVLAKNNSVVALDAATGKEIWSHSPDTPTTIITSRGLNYWESKDGKDR
EEECCEEECCEEEEEECCCCEEEEECCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCC
RLLFCANHSLRAIDARTGKAIATFGVNGRVDLKEGLGREPKNIKLVQSTTPGRVFENLLI
EEEEEECCCEEEEECCCCCEEEEECCCCEEEHHHCCCCCCCCEEEEECCCCHHHHCEEEE
LGSATNEGYTSAPGDLRAFDVRTGAQVWVFHTIPHPGEFGYETWPKDAWKNVGGANVWGE
EECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEE
ISVDEKRGIVYAPTASAKYNFYGADRKGADLFADCLLALDARTGKRIWHFQMVHHDIWDY
EEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCC
DDATAPKLLTLKHEGKMVDAVAQVSKQGFVWVFDRVTGEPLWPIEERAVPKTDMPNEQTW
CCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCC
PTQPFPTKPPPFARQKFTADDLSPFLSAAERAKFRDQILSARNEGLFTPPGLRNTVQMPG
CCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
NNGGANWGGAAIDPTKGTLYVVSKDLPAMLKLEPAGPDRYTSGFGFMLASDGLSPIAPPW
CCCCCCCCCCEECCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCC
SSLTAYDLNEGTIRWQIPLGDVPELAAKGFKNTGSHYPKVGPVVTAGGLIFTGTRDREVR
CCCEEEECCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEECCEEEECCCCCEEE
VLDAETGKLIWEKQVDAALEGMPAVYQVGGREFVVFCASAQVGLIPATQGKVSGAYVAFA
EEECCCCCEEEHHHHHHHHCCCCCEEECCCCEEEEEEECCCEEEEECCCCCCCCEEEEEE
LKR
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002591; 7592351 [H]