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The map label for this gene is iolG [H]

Identifier: 116623837

GI number: 116623837

Start: 6008404

End: 6009576

Strand: Direct

Name: iolG [H]

Synonym: Acid_4749

Alternate gene names: 116623837

Gene position: 6008404-6009576 (Clockwise)

Preceding gene: 116623836

Following gene: 116623838

Centisome position: 60.29

GC content: 61.98

Gene sequence:

>1173_bases
ATGTCCCAGGACCGCCGACAATTTCTCGCCAGTGCTTTGACTGCCGCGCCCTTGTTTGTGCCGCGCAGCGCGTGGGGCGC
CAACGACCGACTTGCGTATGGGCTGATCGGATCGGGAGGACGCGGGCGTTATTTGCAAGGGAACTTCCAGAAGTTGGGCG
CGGAGTGCGTCGCGATCGCGGAGGTTTACGAACCGAATCTCGAGAACGCGCTGAAGACCACGCCCAACGCGAAGAAGTAC
GTGGATTATCGCGACCTGCTGGCGCAGAGCGGAATCGACGCAGTGGTGGTGGCGACGCCCGACCATCAGCATGCGCCCTG
CCTGTTTGCGGCGCTGGACGCGAAGAAGGACGTGTACCTGGAGAAGCCGATGTCGCACTCCGTCGAGGAGAGCCAGCGGA
TGATCCAGGCGGTGCGCAAGACGGACCGGATCGTGCAGATCGGGATGCAGCGGCGCAGCGCTCCGGCGGTGATCGCGGCC
AAGCAGGTCTTCGACAGCGGGATTCTGGGCAAGGTCACGATGGCCAAGCCGATGTGGAACTGGAACGTGTCGAAGCCGCT
GGACAATTCGCCGCTGCCGGGCAAGCTGGATTGGAAGCGCTTCCTGGGCAAGGCGAAGGATCGCGACCTGGAGCCGATGC
GGTTTCGGAGCTGGCGCTACTTCTGGGATTATTCGGGCGGCAACATGACGGACCAGGGAACGCATTTGATGGACGTGGTG
CAGTGGTTCACGGGGGCGGGCTTGGCCAAATCCGCGATCAGCTTCGGGCAGCTGGCGAAGAACACGGGGAGCGAAGTGCC
GGACGTGTTCTGCGCGGTCTTTGAATATCCCAATCTGATGGCGACGTGGACATTGAATTACTGCAACTCCTACGACAACG
ATTGGAGCGTGATGTTCCAGGGCGATCGCGGGACGATGCTGTTGAACACGGCGGGGTATAAGATCTGGGCGGAGCCGTGG
CTGAAGAATCCGCAGCCGGTGCAGGAGATGGCAGCGCCGATTCCGATTGAGCCGCACATTCAGAATTTTATGGACTGCGT
GAAGAGCCGGCAGCAGCCGAACGCCCCGGTGGAAGTGGGGGCCAGCGCGGTGAGCGCTCCGCACCTGGCGAATGTGGCAT
TCCACGGTAACAAGCGCGCGTACCTGAGCGCGGACGGGACTAAGGTAAGTTAA

Upstream 100 bases:

>100_bases
GCAGGCCGGAGCGACAGGCCGGGAGGGCCGGGAGGCCTGTCCTACTGTCGTTGCATCGGGTGGCGCGACGGATTACAGTA
GCGCCAAAGGAGTCACCAGT

Downstream 100 bases:

>100_bases
ACAGGGGGGACACGATGAAGCTTTCGCGAAGACAGATGGCGGGCCTGCTGCCCGCGCTGGCGGCAGCGCAGACTGCGGAG
AAGAAGGCCAAGCCGGTGTT

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSQDRRQFLASALTAAPLFVPRSAWGANDRLAYGLIGSGGRGRYLQGNFQKLGAECVAIAEVYEPNLENALKTTPNAKKY
VDYRDLLAQSGIDAVVVATPDHQHAPCLFAALDAKKDVYLEKPMSHSVEESQRMIQAVRKTDRIVQIGMQRRSAPAVIAA
KQVFDSGILGKVTMAKPMWNWNVSKPLDNSPLPGKLDWKRFLGKAKDRDLEPMRFRSWRYFWDYSGGNMTDQGTHLMDVV
QWFTGAGLAKSAISFGQLAKNTGSEVPDVFCAVFEYPNLMATWTLNYCNSYDNDWSVMFQGDRGTMLLNTAGYKIWAEPW
LKNPQPVQEMAAPIPIEPHIQNFMDCVKSRQQPNAPVEVGASAVSAPHLANVAFHGNKRAYLSADGTKVS

Sequences:

>Translated_390_residues
MSQDRRQFLASALTAAPLFVPRSAWGANDRLAYGLIGSGGRGRYLQGNFQKLGAECVAIAEVYEPNLENALKTTPNAKKY
VDYRDLLAQSGIDAVVVATPDHQHAPCLFAALDAKKDVYLEKPMSHSVEESQRMIQAVRKTDRIVQIGMQRRSAPAVIAA
KQVFDSGILGKVTMAKPMWNWNVSKPLDNSPLPGKLDWKRFLGKAKDRDLEPMRFRSWRYFWDYSGGNMTDQGTHLMDVV
QWFTGAGLAKSAISFGQLAKNTGSEVPDVFCAVFEYPNLMATWTLNYCNSYDNDWSVMFQGDRGTMLLNTAGYKIWAEPW
LKNPQPVQEMAAPIPIEPHIQNFMDCVKSRQQPNAPVEVGASAVSAPHLANVAFHGNKRAYLSADGTKVS
>Mature_389_residues
SQDRRQFLASALTAAPLFVPRSAWGANDRLAYGLIGSGGRGRYLQGNFQKLGAECVAIAEVYEPNLENALKTTPNAKKYV
DYRDLLAQSGIDAVVVATPDHQHAPCLFAALDAKKDVYLEKPMSHSVEESQRMIQAVRKTDRIVQIGMQRRSAPAVIAAK
QVFDSGILGKVTMAKPMWNWNVSKPLDNSPLPGKLDWKRFLGKAKDRDLEPMRFRSWRYFWDYSGGNMTDQGTHLMDVVQ
WFTGAGLAKSAISFGQLAKNTGSEVPDVFCAVFEYPNLMATWTLNYCNSYDNDWSVMFQGDRGTMLLNTAGYKIWAEPWL
KNPQPVQEMAAPIPIEPHIQNFMDCVKSRQQPNAPVEVGASAVSAPHLANVAFHGNKRAYLSADGTKVS

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 43326; Mature: 43195

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDRRQFLASALTAAPLFVPRSAWGANDRLAYGLIGSGGRGRYLQGNFQKLGAECVAIA
CCHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCHHHHHHH
EVYEPNLENALKTTPNAKKYVDYRDLLAQSGIDAVVVATPDHQHAPCLFAALDAKKDVYL
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEEE
EKPMSHSVEESQRMIQAVRKTDRIVQIGMQRRSAPAVIAAKQVFDSGILGKVTMAKPMWN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCC
WNVSKPLDNSPLPGKLDWKRFLGKAKDRDLEPMRFRSWRYFWDYSGGNMTDQGTHLMDVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHCCEEEEEEECCCCCCCCCHHHHHHH
QWFTGAGLAKSAISFGQLAKNTGSEVPDVFCAVFEYPNLMATWTLNYCNSYDNDWSVMFQ
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEEHHHCCCCCCEEEEEE
GDRGTMLLNTAGYKIWAEPWLKNPQPVQEMAAPIPIEPHIQNFMDCVKSRQQPNAPVEVG
CCCCEEEEECCCCEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHC
ASAVSAPHLANVAFHGNKRAYLSADGTKVS
HHHHCCCCCEEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure 
SQDRRQFLASALTAAPLFVPRSAWGANDRLAYGLIGSGGRGRYLQGNFQKLGAECVAIA
CHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCHHHHHHH
EVYEPNLENALKTTPNAKKYVDYRDLLAQSGIDAVVVATPDHQHAPCLFAALDAKKDVYL
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCEEE
EKPMSHSVEESQRMIQAVRKTDRIVQIGMQRRSAPAVIAAKQVFDSGILGKVTMAKPMWN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCC
WNVSKPLDNSPLPGKLDWKRFLGKAKDRDLEPMRFRSWRYFWDYSGGNMTDQGTHLMDVV
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHCCEEEEEEECCCCCCCCCHHHHHHH
QWFTGAGLAKSAISFGQLAKNTGSEVPDVFCAVFEYPNLMATWTLNYCNSYDNDWSVMFQ
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEEHHHCCCCCCEEEEEE
GDRGTMLLNTAGYKIWAEPWLKNPQPVQEMAAPIPIEPHIQNFMDCVKSRQQPNAPVEVG
CCCCEEEEECCCCEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHC
ASAVSAPHLANVAFHGNKRAYLSADGTKVS
HHHHCCCCCEEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA