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The map label for this gene is lgrB [H]

Identifier: 116623804

GI number: 116623804

Start: 5969551

End: 5971506

Strand: Reverse

Name: lgrB [H]

Synonym: Acid_4716

Alternate gene names: 116623804

Gene position: 5971506-5969551 (Counterclockwise)

Preceding gene: 116623806

Following gene: 116623803

Centisome position: 59.92

GC content: 67.23

Gene sequence:

>1956_bases
ATGCGCGAGCTAGGTCTCCCCGGCGAAATTCGTTTTGCCGCCTACAATCAGGTTTTTCAAGAACTTCTGGACCCCGCCGG
ACTCTTCGCGCGCAATACGACGGGCGCGAATATCGTTCTCGTCCGCTTCGAGGATTGGACCTTGGGACAGGCCGGCGAGT
TCGTTGACGCCGTGCGCGCGGCGGCCGGCCGCCTGGCGGTTCCGCTGCTCATCGTCCTTTGCGCGGGCACTGGCGAGTTC
GACGACCGGATGCGCGCGAGTGTCGCCGGGCTGCCCTCCGTTCACCTGATCACGGCCGCCGAGATCGCCGCGCTCTATCC
CGTCCGAGACCTGCACGATCCGCACGCGAATGAACTCGGCCACGTGCCCTACACGCCGCTGTACTTCGTGGCACTGGCCA
CCGCCATCGCGCGCAAAATCCACGCCATCACGGCGCCGCCCTTCAAGGTGATTGCGCTCGATTGCGACGACACGCTGTGG
GCGGGCATCTGCGGCGAGGATGGGCCCGAGGGTGTGGTGCTCGATCCGCCGCGCCTGGCCCTGCAGCAGTTCATGCGCGC
GCGCCGCCAGGAGGGCATGCTGCTGGCGCTTTGCAGCAAGAACAATGAAGAGGATGTCGCCGCCACCTTCGCCGCGCATC
CCGAGATGCCGCTCCGGTTGGAGGATTTCGCCGCGCAGCGCGTCAACTGGGAGACCAAGGGCGCCAACCTGGTCTCGCTC
GCCGACGAACTCGATCTCGGGCTGGACAGCGTCATCCTGATTGACGACAATCCCAAGGAAGTCACCGAGGCGCAGGCCGG
CGCTCCGCAGGCGCTGGCGATTGCGCTGCCCGAGCGGGCCGCGGAGATCCCGGAGTTCCTGCGCCACGTCTGGGCCTTCG
ACCGCGCCCGCGTCACGGAAGAAGACCGGCGGCGTCCCGAGCTCTACGCGCAGCGCGCGGAGCGTGTGCGCGCGCAGCGC
AGTTCCGCCAGCCTTGAGGAATTTCTCGCTTCGCTGAAACTCGAGGTCGCGATCGCTCCCCTGGAGGCCGCGCAGGCCGA
CCGGGTGGCGCAACTCACGCAGCGCACCAACCAGATGAACGCGACCTGCATCCGGCGCACCGCCGCCGAGATCCAGCGCC
TGGCCGCGGAGTGCCTCACGGTTAAGGTAACCGACCGTTTCGGCAGCTATGGACTGACCGGGGTCATCCTCTTTCGCACC
GATGCCACGGCGCTCATCGTGGACACCTTCCTGCTCAGTTGCCGCGCTTTGGGCCGCGGCGTGGAGCACCGGATGGTGGC
GCGGCTTGGCGAAATCGCCCAGGAGCGCGGCCTGAAGCGTGTCGAGCTTCCCTTTGTCGAAGGCCAGCGCAATCGGCCGG
CTCTGCTCTTCCTGCAATCGCTGGCCGCGCAGGATCCCGATGGCGTTTTCCGCCTTGACGCAGCGCGGGCGTCCCAGGTG
CGATATCAACCCGGGGCGGGGAAGCCGGCCGACCTGCCCGCCGGGGAGGGCCGCCCCGCGGCGGCCGTGCCGTTGCGCAT
TCCGTACGCCCGCATCGCCGCCGAATTGCGCGAGCCCGAGATGATTCTGGCGCACATCCGCGCGACTTCGCGGCGCGCTG
CCGGCATTCGTGATGTCGAGCCGCCGCGCACCGCGTTGGAGCGCGATCTGGTGGAGCTCTGGGCCGAGCTGCTCAACGTG
GAGGCGCTCGGCGTACACGAGAACTTCTTCGAACTCGGAGGCCATTCCCTGCTCGCGGTACAGCTGCTTTCGCGCGTGCG
CCAACTCTACGGAGTGGAGCTTTCGCTCGAGGTGGTGTACTCCGGAGAGTTCACGGTGGCCGAGCTGGCGAAGGCGATCG
AGCTCAAGGAGATCGAACACTCCGGCGGGGATTATCACGAACTGCTCCAGGAACTCGACGGCCTCAGCGACGAGGAAGTG
CGCGCACTTCTGGCTGAAGAGCAGGATGCCTCATAG

Upstream 100 bases:

>100_bases
TTCGGGCGAGGCCATAAGGCCTTCAATATAATGGAATTTGCAGATCGCGATCAGCGCCACCTTCACCGCCGAAGCCATCC
AGCCCGGATTGTCTTTCTGG

Downstream 100 bases:

>100_bases
CGCATGCGGATTCTGTTGACGGCGAATGCAAGTTACGTGCCGCCGCGCGGCGGCGCTACGCGCAGCAATCTGATCTGGAT
GGACCAGATGGCCGGCGCGG

Product: FkbH like protein

Products: NA

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MRELGLPGEIRFAAYNQVFQELLDPAGLFARNTTGANIVLVRFEDWTLGQAGEFVDAVRAAAGRLAVPLLIVLCAGTGEF
DDRMRASVAGLPSVHLITAAEIAALYPVRDLHDPHANELGHVPYTPLYFVALATAIARKIHAITAPPFKVIALDCDDTLW
AGICGEDGPEGVVLDPPRLALQQFMRARRQEGMLLALCSKNNEEDVAATFAAHPEMPLRLEDFAAQRVNWETKGANLVSL
ADELDLGLDSVILIDDNPKEVTEAQAGAPQALAIALPERAAEIPEFLRHVWAFDRARVTEEDRRRPELYAQRAERVRAQR
SSASLEEFLASLKLEVAIAPLEAAQADRVAQLTQRTNQMNATCIRRTAAEIQRLAAECLTVKVTDRFGSYGLTGVILFRT
DATALIVDTFLLSCRALGRGVEHRMVARLGEIAQERGLKRVELPFVEGQRNRPALLFLQSLAAQDPDGVFRLDAARASQV
RYQPGAGKPADLPAGEGRPAAAVPLRIPYARIAAELREPEMILAHIRATSRRAAGIRDVEPPRTALERDLVELWAELLNV
EALGVHENFFELGGHSLLAVQLLSRVRQLYGVELSLEVVYSGEFTVAELAKAIELKEIEHSGGDYHELLQELDGLSDEEV
RALLAEEQDAS

Sequences:

>Translated_651_residues
MRELGLPGEIRFAAYNQVFQELLDPAGLFARNTTGANIVLVRFEDWTLGQAGEFVDAVRAAAGRLAVPLLIVLCAGTGEF
DDRMRASVAGLPSVHLITAAEIAALYPVRDLHDPHANELGHVPYTPLYFVALATAIARKIHAITAPPFKVIALDCDDTLW
AGICGEDGPEGVVLDPPRLALQQFMRARRQEGMLLALCSKNNEEDVAATFAAHPEMPLRLEDFAAQRVNWETKGANLVSL
ADELDLGLDSVILIDDNPKEVTEAQAGAPQALAIALPERAAEIPEFLRHVWAFDRARVTEEDRRRPELYAQRAERVRAQR
SSASLEEFLASLKLEVAIAPLEAAQADRVAQLTQRTNQMNATCIRRTAAEIQRLAAECLTVKVTDRFGSYGLTGVILFRT
DATALIVDTFLLSCRALGRGVEHRMVARLGEIAQERGLKRVELPFVEGQRNRPALLFLQSLAAQDPDGVFRLDAARASQV
RYQPGAGKPADLPAGEGRPAAAVPLRIPYARIAAELREPEMILAHIRATSRRAAGIRDVEPPRTALERDLVELWAELLNV
EALGVHENFFELGGHSLLAVQLLSRVRQLYGVELSLEVVYSGEFTVAELAKAIELKEIEHSGGDYHELLQELDGLSDEEV
RALLAEEQDAS
>Mature_651_residues
MRELGLPGEIRFAAYNQVFQELLDPAGLFARNTTGANIVLVRFEDWTLGQAGEFVDAVRAAAGRLAVPLLIVLCAGTGEF
DDRMRASVAGLPSVHLITAAEIAALYPVRDLHDPHANELGHVPYTPLYFVALATAIARKIHAITAPPFKVIALDCDDTLW
AGICGEDGPEGVVLDPPRLALQQFMRARRQEGMLLALCSKNNEEDVAATFAAHPEMPLRLEDFAAQRVNWETKGANLVSL
ADELDLGLDSVILIDDNPKEVTEAQAGAPQALAIALPERAAEIPEFLRHVWAFDRARVTEEDRRRPELYAQRAERVRAQR
SSASLEEFLASLKLEVAIAPLEAAQADRVAQLTQRTNQMNATCIRRTAAEIQRLAAECLTVKVTDRFGSYGLTGVILFRT
DATALIVDTFLLSCRALGRGVEHRMVARLGEIAQERGLKRVELPFVEGQRNRPALLFLQSLAAQDPDGVFRLDAARASQV
RYQPGAGKPADLPAGEGRPAAAVPLRIPYARIAAELREPEMILAHIRATSRRAAGIRDVEPPRTALERDLVELWAELLNV
EALGVHENFFELGGHSLLAVQLLSRVRQLYGVELSLEVVYSGEFTVAELAKAIELKEIEHSGGDYHELLQELDGLSDEEV
RALLAEEQDAS

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG3882

COG function: function code Q; Predicted enzyme involved in methoxymalonyl-ACP biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 71399; Mature: 71399

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELGLPGEIRFAAYNQVFQELLDPAGLFARNTTGANIVLVRFEDWTLGQAGEFVDAVRA
CCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
AAGRLAVPLLIVLCAGTGEFDDRMRASVAGLPSVHLITAAEIAALYPVRDLHDPHANELG
HHCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHCCCCCCCCCC
HVPYTPLYFVALATAIARKIHAITAPPFKVIALDCDDTLWAGICGEDGPEGVVLDPPRLA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCCEEECCHHHH
LQQFMRARRQEGMLLALCSKNNEEDVAATFAAHPEMPLRLEDFAAQRVNWETKGANLVSL
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
ADELDLGLDSVILIDDNPKEVTEAQAGAPQALAIALPERAAEIPEFLRHVWAFDRARVTE
HHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCH
EDRRRPELYAQRAERVRAQRSSASLEEFLASLKLEVAIAPLEAAQADRVAQLTQRTNQMN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHH
ATCIRRTAAEIQRLAAECLTVKVTDRFGSYGLTGVILFRTDATALIVDTFLLSCRALGRG
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC
VEHRMVARLGEIAQERGLKRVELPFVEGQRNRPALLFLQSLAAQDPDGVFRLDAARASQV
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHCE
RYQPGAGKPADLPAGEGRPAAAVPLRIPYARIAAELREPEMILAHIRATSRRAAGIRDVE
EECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
PPRTALERDLVELWAELLNVEALGVHENFFELGGHSLLAVQLLSRVRQLYGVELSLEVVY
CHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEE
SGEFTVAELAKAIELKEIEHSGGDYHELLQELDGLSDEEVRALLAEEQDAS
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRELGLPGEIRFAAYNQVFQELLDPAGLFARNTTGANIVLVRFEDWTLGQAGEFVDAVRA
CCCCCCCCCCHHHHHHHHHHHHHCCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
AAGRLAVPLLIVLCAGTGEFDDRMRASVAGLPSVHLITAAEIAALYPVRDLHDPHANELG
HHCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHCCCCCCCCCC
HVPYTPLYFVALATAIARKIHAITAPPFKVIALDCDDTLWAGICGEDGPEGVVLDPPRLA
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCCEEECCHHHH
LQQFMRARRQEGMLLALCSKNNEEDVAATFAAHPEMPLRLEDFAAQRVNWETKGANLVSL
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
ADELDLGLDSVILIDDNPKEVTEAQAGAPQALAIALPERAAEIPEFLRHVWAFDRARVTE
HHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCH
EDRRRPELYAQRAERVRAQRSSASLEEFLASLKLEVAIAPLEAAQADRVAQLTQRTNQMN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHH
ATCIRRTAAEIQRLAAECLTVKVTDRFGSYGLTGVILFRTDATALIVDTFLLSCRALGRG
HHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCC
VEHRMVARLGEIAQERGLKRVELPFVEGQRNRPALLFLQSLAAQDPDGVFRLDAARASQV
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHCE
RYQPGAGKPADLPAGEGRPAAAVPLRIPYARIAAELREPEMILAHIRATSRRAAGIRDVE
EECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
PPRTALERDLVELWAELLNVEALGVHENFFELGGHSLLAVQLLSRVRQLYGVELSLEVVY
CHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEE
SGEFTVAELAKAIELKEIEHSGGDYHELLQELDGLSDEEVRALLAEEQDAS
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA