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The map label for this gene is macB [H]

Identifier: 116623219

GI number: 116623219

Start: 5240962

End: 5242200

Strand: Reverse

Name: macB [H]

Synonym: Acid_4126

Alternate gene names: 116623219

Gene position: 5242200-5240962 (Counterclockwise)

Preceding gene: 116623220

Following gene: 116623218

Centisome position: 52.6

GC content: 59.32

Gene sequence:

>1239_bases
ATGACATCGCACGCGTCTTTCTGGGAGGCGGTCAAGGGCGCACTCCAATCACTTCGCGGCAGTAAGCTGCGCAGCTTCCT
GACCTTGCTCGGGATTATTTTGGCGACCACGACGCTGATCGCGGTCATGTCCGTAATCAGCGGTATGGACGTCTACATCG
CGCAGAACGTTTCCAGCATGGGCGCCGATGGATATCGCGTGCAGCGCATCGTCATGATGGGCTTCGATCCCAAGAAGTAC
ATGGAGATGCTGCGCCGCAATCCTCAACTGAGCCGCGACGAGTACGATTTTCTGCGATCGCGATTGACGATGACGAATGA
ACTCGGGATCAGCACCGGCCGCTCGGTCTCGATTCATCGCGGCACGGAGATATCCGAAGGCGTGGGACTGCAGGGAGCGA
CGCCCAACATCGGCGTGATCACGAATTTCGACGCGGAAGAAGGGCGCTTCATTTCCGAGACCGAGAACGACCGGCATATG
AACGTCGCCTTCATCGGCCACGATTTGAAAGACAAGTTCTTTGCGGGGCAGAGCGCCATAGGACAGACCATTAATGCCGA
GGGCGTGGTGTTCGAAGTAGTGGGCGTGGCGAAAGCGAAGGGCTCCGTGTTCGGCCAGTCTCAAGACAATTTCCTGGTGA
TTCCGGTCAACACGTATTTCAAGATCTGGGGCGCGCGCAACGGCATGCAGTTCGCGGGCACCGCCATCGATCACGATCAT
CTTTTGCAGGCGCAGGAAGAGGCGCGCATGCTGCTGCGCTCTTACCGGCACCTCAAACCCAAAGAGGACGATACATTCAG
CATGCTGACCTCCGACGCGCTGCTGAATTTCTGGAACCAGTTGACCGGCGCGATTGCGGCAACGGCGGTGGCGGTGGTTT
CGGTCTTTCTGGTGGTGGGCGGCATCGTGATTATGAACATCATGCTCGCGGTGGTGACCGAGCGGACTCATGAAATCGGG
ATCCGCAAGTCGGTGGGTGCGCGCAGCCGCGACATCCTCAATCAATTCCTGGTGGAATCGGCGATGCTCTCGGCCAGCGG
CGGATTGATCGGCGTAGCGATCGCGTGGATCGTCGCGGTGCTGGTGCGGACACTGACGCCGGTGCCGATGTCGGTGCCGG
TGATGGCCGTGTTCGTGGGCGTCACGTTGTCCGCGGTGGTCGGACTGTTCTTTGGAATCTATCCGGCGCAGCGCGCCGCG
AAACTCGATCCGATCGAAGCGCTGAGGGCGGAAAAATGA

Upstream 100 bases:

>100_bases
GGCGAGGGGGCCTCACCGTTTTTGGGCGGATCAGATGATAATGGAGTGGATTGTCGCGGATCCTGTTAATAACGTGGTAA
ATCAATCGTCTAAGGCTTGA

Downstream 100 bases:

>100_bases
GTTTATTTTCGATTCTCGCCGGTGTGAGATTGGCGCTGGATACGATACGGGCGCATAAGCTGCGGTCGTTCCTGACGGTG
CTGGGCGTGATCATCGGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTSHASFWEAVKGALQSLRGSKLRSFLTLLGIILATTTLIAVMSVISGMDVYIAQNVSSMGADGYRVQRIVMMGFDPKKY
MEMLRRNPQLSRDEYDFLRSRLTMTNELGISTGRSVSIHRGTEISEGVGLQGATPNIGVITNFDAEEGRFISETENDRHM
NVAFIGHDLKDKFFAGQSAIGQTINAEGVVFEVVGVAKAKGSVFGQSQDNFLVIPVNTYFKIWGARNGMQFAGTAIDHDH
LLQAQEEARMLLRSYRHLKPKEDDTFSMLTSDALLNFWNQLTGAIAATAVAVVSVFLVVGGIVIMNIMLAVVTERTHEIG
IRKSVGARSRDILNQFLVESAMLSASGGLIGVAIAWIVAVLVRTLTPVPMSVPVMAVFVGVTLSAVVGLFFGIYPAQRAA
KLDPIEALRAEK

Sequences:

>Translated_412_residues
MTSHASFWEAVKGALQSLRGSKLRSFLTLLGIILATTTLIAVMSVISGMDVYIAQNVSSMGADGYRVQRIVMMGFDPKKY
MEMLRRNPQLSRDEYDFLRSRLTMTNELGISTGRSVSIHRGTEISEGVGLQGATPNIGVITNFDAEEGRFISETENDRHM
NVAFIGHDLKDKFFAGQSAIGQTINAEGVVFEVVGVAKAKGSVFGQSQDNFLVIPVNTYFKIWGARNGMQFAGTAIDHDH
LLQAQEEARMLLRSYRHLKPKEDDTFSMLTSDALLNFWNQLTGAIAATAVAVVSVFLVVGGIVIMNIMLAVVTERTHEIG
IRKSVGARSRDILNQFLVESAMLSASGGLIGVAIAWIVAVLVRTLTPVPMSVPVMAVFVGVTLSAVVGLFFGIYPAQRAA
KLDPIEALRAEK
>Mature_411_residues
TSHASFWEAVKGALQSLRGSKLRSFLTLLGIILATTTLIAVMSVISGMDVYIAQNVSSMGADGYRVQRIVMMGFDPKKYM
EMLRRNPQLSRDEYDFLRSRLTMTNELGISTGRSVSIHRGTEISEGVGLQGATPNIGVITNFDAEEGRFISETENDRHMN
VAFIGHDLKDKFFAGQSAIGQTINAEGVVFEVVGVAKAKGSVFGQSQDNFLVIPVNTYFKIWGARNGMQFAGTAIDHDHL
LQAQEEARMLLRSYRHLKPKEDDTFSMLTSDALLNFWNQLTGAIAATAVAVVSVFLVVGGIVIMNIMLAVVTERTHEIGI
RKSVGARSRDILNQFLVESAMLSASGGLIGVAIAWIVAVLVRTLTPVPMSVPVMAVFVGVTLSAVVGLFFGIYPAQRAAK
LDPIEALRAEK

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=28.2926829268293, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44823; Mature: 44691

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHASFWEAVKGALQSLRGSKLRSFLTLLGIILATTTLIAVMSVISGMDVYIAQNVSSM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHC
GADGYRVQRIVMMGFDPKKYMEMLRRNPQLSRDEYDFLRSRLTMTNELGISTGRSVSIHR
CCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEC
GTEISEGVGLQGATPNIGVITNFDAEEGRFISETENDRHMNVAFIGHDLKDKFFAGQSAI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCEEEEEEECCCHHHHHHCCHHHH
GQTINAEGVVFEVVGVAKAKGSVFGQSQDNFLVIPVNTYFKIWGARNGMQFAGTAIDHDH
CCCCCCCCEEEEEEHHHHHCCCCCCCCCCCEEEEECHHEEEEECCCCCCCCCCCCCCHHH
LLQAQEEARMLLRSYRHLKPKEDDTFSMLTSDALLNFWNQLTGAIAATAVAVVSVFLVVG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVIMNIMLAVVTERTHEIGIRKSVGARSRDILNQFLVESAMLSASGGLIGVAIAWIVAV
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVRTLTPVPMSVPVMAVFVGVTLSAVVGLFFGIYPAQRAAKLDPIEALRAEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
TSHASFWEAVKGALQSLRGSKLRSFLTLLGIILATTTLIAVMSVISGMDVYIAQNVSSM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHC
GADGYRVQRIVMMGFDPKKYMEMLRRNPQLSRDEYDFLRSRLTMTNELGISTGRSVSIHR
CCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEC
GTEISEGVGLQGATPNIGVITNFDAEEGRFISETENDRHMNVAFIGHDLKDKFFAGQSAI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCEEEEEEECCCHHHHHHCCHHHH
GQTINAEGVVFEVVGVAKAKGSVFGQSQDNFLVIPVNTYFKIWGARNGMQFAGTAIDHDH
CCCCCCCCEEEEEEHHHHHCCCCCCCCCCCEEEEECHHEEEEECCCCCCCCCCCCCCHHH
LLQAQEEARMLLRSYRHLKPKEDDTFSMLTSDALLNFWNQLTGAIAATAVAVVSVFLVVG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVIMNIMLAVVTERTHEIGIRKSVGARSRDILNQFLVESAMLSASGGLIGVAIAWIVAV
HHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVRTLTPVPMSVPVMAVFVGVTLSAVVGLFFGIYPAQRAAKLDPIEALRAEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA