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The map label for this gene is macB [H]

Identifier: 116623218

GI number: 116623218

Start: 5239739

End: 5240965

Strand: Reverse

Name: macB [H]

Synonym: Acid_4125

Alternate gene names: 116623218

Gene position: 5240965-5239739 (Counterclockwise)

Preceding gene: 116623219

Following gene: 116623216

Centisome position: 52.59

GC content: 63.81

Gene sequence:

>1227_bases
ATGAGTTTATTTTCGATTCTCGCCGGTGTGAGATTGGCGCTGGATACGATACGGGCGCATAAGCTGCGGTCGTTCCTGAC
GGTGCTGGGCGTGATCATCGGCACCGGCGCGGTGATCGGTGTGGGCTCCATCATCGCCGGCTTGGATGGCGCGATCACCA
ACATGCTGCGCAGCTTCGGGCCGAACACCGTGATCGTCACCAAGACGACGGCGATGGGCAATGCCAGCCGCGAAGAACGG
CGCCGCCGTCCGCTGGAGCTGGAGAATGCGCGCGCCATCGCGGAGCGCTGCACCTCAGTGGAACATGTCAGCCCTTTCCT
GTTCGCGCCGAATGGAATTCACACGGCGCGCTACAAGGGCAACGACCTGTACAACATTCAACTGGGCGGCACCGAGGAAG
GCTACGCCGCCGGCGGCACCACGATGAAGGCCGGCCGATTCTTCACGGACCTGGAGAATTCGCACCACATGCCGATCGTA
GTGATCGGCGAAGACGTGCAGAAGCAGCTGCTGGCCAACGAGACTCCGATCGGCAAACGGATCACGGTGGACGGGCACGA
GCTGGAAGTGGTCGGCGTGATGGATCGTCCCGCGGCGTCGCTGCCCGGGCAGGACGACACGCGCATTCTGATTCCATACT
TTACGATGCGCAAGATGTTTCCGAGCGCGCGCGAACACATGCTGGTAGTGATCGCGTATCCGGGCATGATTACGCAGGCG
CAGGACGAGGTGCGCGCCGTGCTGCGCATTGCGCGGAGAGTGCCCTACAACGGCGTGGACACCTTTTCGATCACGACCGC
GGAGCAGATGATCGAGCAGTTCCACAACGTGACCGCCACCGTCGCGATCGTGATGGTGATTCTGAGCTCGATCGGTCTGC
TGGTGGGCGGCATCGGGGTGATGAACATTATGCTGGTGAGCGTCACGGAGCGCACGCGCGAGATCGGAGTGCGCAAAGCG
ATCGGGGCGCGCCGCAGCGACATCGTGGTGCAGTTCCTGACCGAGGCCGTGGTACTGACGGCGTTGGGCGGAGTGCTGGG
ACTGCTGTTGGGCTGGACGATTTCGCGCGCCGCCGGTTTGGTATTTCCGAATCTGCCGACCGCGGTGCCGCTGTGGGCGG
CGACGGCGGGAGTGCTGGTCTCGGTCGGCGTCGGCCTGTTTTTCGGGATCTGGCCGGCGAGCCGCGCCGCGCGCCTCGAC
CCCGTGGAAGCACTGCGCTACGAATAG

Upstream 100 bases:

>100_bases
TGGGCGTCACGTTGTCCGCGGTGGTCGGACTGTTCTTTGGAATCTATCCGGCGCAGCGCGCCGCGAAACTCGATCCGATC
GAAGCGCTGAGGGCGGAAAA

Downstream 100 bases:

>100_bases
CCCTCAGCGCACTGCGAGGGTAACGCCGGCAGGACTGGTGACACCGGCAATCGTGATATCGAGCGGTACGGTCGCACTGG
GTGCAATGCCGATCGGCACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLFSILAGVRLALDTIRAHKLRSFLTVLGVIIGTGAVIGVGSIIAGLDGAITNMLRSFGPNTVIVTKTTAMGNASREER
RRRPLELENARAIAERCTSVEHVSPFLFAPNGIHTARYKGNDLYNIQLGGTEEGYAAGGTTMKAGRFFTDLENSHHMPIV
VIGEDVQKQLLANETPIGKRITVDGHELEVVGVMDRPAASLPGQDDTRILIPYFTMRKMFPSAREHMLVVIAYPGMITQA
QDEVRAVLRIARRVPYNGVDTFSITTAEQMIEQFHNVTATVAIVMVILSSIGLLVGGIGVMNIMLVSVTERTREIGVRKA
IGARRSDIVVQFLTEAVVLTALGGVLGLLLGWTISRAAGLVFPNLPTAVPLWAATAGVLVSVGVGLFFGIWPASRAARLD
PVEALRYE

Sequences:

>Translated_408_residues
MSLFSILAGVRLALDTIRAHKLRSFLTVLGVIIGTGAVIGVGSIIAGLDGAITNMLRSFGPNTVIVTKTTAMGNASREER
RRRPLELENARAIAERCTSVEHVSPFLFAPNGIHTARYKGNDLYNIQLGGTEEGYAAGGTTMKAGRFFTDLENSHHMPIV
VIGEDVQKQLLANETPIGKRITVDGHELEVVGVMDRPAASLPGQDDTRILIPYFTMRKMFPSAREHMLVVIAYPGMITQA
QDEVRAVLRIARRVPYNGVDTFSITTAEQMIEQFHNVTATVAIVMVILSSIGLLVGGIGVMNIMLVSVTERTREIGVRKA
IGARRSDIVVQFLTEAVVLTALGGVLGLLLGWTISRAAGLVFPNLPTAVPLWAATAGVLVSVGVGLFFGIWPASRAARLD
PVEALRYE
>Mature_407_residues
SLFSILAGVRLALDTIRAHKLRSFLTVLGVIIGTGAVIGVGSIIAGLDGAITNMLRSFGPNTVIVTKTTAMGNASREERR
RRPLELENARAIAERCTSVEHVSPFLFAPNGIHTARYKGNDLYNIQLGGTEEGYAAGGTTMKAGRFFTDLENSHHMPIVV
IGEDVQKQLLANETPIGKRITVDGHELEVVGVMDRPAASLPGQDDTRILIPYFTMRKMFPSAREHMLVVIAYPGMITQAQ
DEVRAVLRIARRVPYNGVDTFSITTAEQMIEQFHNVTATVAIVMVILSSIGLLVGGIGVMNIMLVSVTERTREIGVRKAI
GARRSDIVVQFLTEAVVLTALGGVLGLLLGWTISRAAGLVFPNLPTAVPLWAATAGVLVSVGVGLFFGIWPASRAARLDP
VEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=400, Percent_Identity=30.25, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43964; Mature: 43833

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSILAGVRLALDTIRAHKLRSFLTVLGVIIGTGAVIGVGSIIAGLDGAITNMLRSFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCC
PNTVIVTKTTAMGNASREERRRRPLELENARAIAERCTSVEHVSPFLFAPNGIHTARYKG
CCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCCEEEEECC
NDLYNIQLGGTEEGYAAGGTTMKAGRFFTDLENSHHMPIVVIGEDVQKQLLANETPIGKR
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHCCCCCCCCE
ITVDGHELEVVGVMDRPAASLPGQDDTRILIPYFTMRKMFPSAREHMLVVIAYPGMITQA
EEECCCEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHH
QDEVRAVLRIARRVPYNGVDTFSITTAEQMIEQFHNVTATVAIVMVILSSIGLLVGGIGV
HHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIMLVSVTERTREIGVRKAIGARRSDIVVQFLTEAVVLTALGGVLGLLLGWTISRAAGL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VFPNLPTAVPLWAATAGVLVSVGVGLFFGIWPASRAARLDPVEALRYE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
SLFSILAGVRLALDTIRAHKLRSFLTVLGVIIGTGAVIGVGSIIAGLDGAITNMLRSFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCC
PNTVIVTKTTAMGNASREERRRRPLELENARAIAERCTSVEHVSPFLFAPNGIHTARYKG
CCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCCEEEEECC
NDLYNIQLGGTEEGYAAGGTTMKAGRFFTDLENSHHMPIVVIGEDVQKQLLANETPIGKR
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHCCCCCCCCE
ITVDGHELEVVGVMDRPAASLPGQDDTRILIPYFTMRKMFPSAREHMLVVIAYPGMITQA
EEECCCEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHH
QDEVRAVLRIARRVPYNGVDTFSITTAEQMIEQFHNVTATVAIVMVILSSIGLLVGGIGV
HHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIMLVSVTERTREIGVRKAIGARRSDIVVQFLTEAVVLTALGGVLGLLLGWTISRAAGL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VFPNLPTAVPLWAATAGVLVSVGVGLFFGIWPASRAARLDPVEALRYE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA