Click here to switch to the map view.

The map label for this gene is yflS [H]

Identifier: 116623179

GI number: 116623179

Start: 5193891

End: 5195264

Strand: Direct

Name: yflS [H]

Synonym: Acid_4086

Alternate gene names: 116623179

Gene position: 5193891-5195264 (Clockwise)

Preceding gene: 116623178

Following gene: 116623180

Centisome position: 52.12

GC content: 64.19

Gene sequence:

>1374_bases
GTGGTGATTGTGCCGGGGGTGGTGCTGTATTTCAATCCGCTGCCGGGAATGAACGCGGGGCAGGAGCACCTGTTCGCATT
TTTCGTGGCGACGATCATCGCGCTGGTGGCGCAGCCGGTGCCGATGGGAGTGAGCGTGCTGCTGGCGATGACGCTGGTGG
TAGTGACGGGGACGCTGACCGCGGCGAAGGTGCTGTCGGGGTTTGGGAACGTCACGGTCTGGCTGGTATTCACGGCATTT
CTGTTTTCGCGGGCGGTGACGCAGACGGGATTCGGAATGCGGGTCGGATACCTGTTCATCGAACGCTTCGGAAAGACGCC
GCTGCGGCTGGGGTATGCGCTGGCGGGGGCCGACCTGGTGCTGGCGCCGTTCATTCCGTCGGACACGGCGCGCGGGGGCG
GAGTGGTTTTCCCTGTCACGCGGAGCGTGGCGAAGGCGTTCGGGTCGGAGCCGGGGGCGACGGCGCGGAAGATGGGTTCG
TTCCTGATGCTGGTCTCGTTCCACACGACCTACACGGCATCGGCGATGTTCCTGACCGGGATGGCGGCGAACCCGTTGAT
CGCGGAGTTCGCGTATAAGATTGGGCACGTCGAGCTGACGTGGGGCCGCTGGCTCTCGGGATCGATTCTGCCGGGGATGC
TGACGCTGGCGTTCGTGCCGTGGCTGTTGTTCCGGCTGGCGCGTCCGGAGATTCAGGACACGACGGCGGCGCGAGAGATG
GCGCGGAAGGAACTGGCGCGGCGCGGGCCGATGGGGCGCGAGGAGAAGTGGCTGGTCGCAATCATGGGGGCGGTGATGGC
AGGATGGGTGACCTCTCCGTGGCATGGATTACCGAATACGTTCGTGGCGCTGAGCGGGTTGTGCGCGCTGCTTCTGGCGC
GGGTAATCGCATGGGAGGATCTGCTGGCCGAGCATCGGGCATGGGATGCGCTCATCTGGTTCGCGCCGCTGGTGATGATG
GCGGACGCGATGAACGAGAACGGAGCCATCAAGATCTTAAGCGGCGGACTCTTCGGACTGGTTCACGGCTGGCCGTGGCT
GATGGTATTGCTCCTGCTGGTGACGGCTTACTGTTATGTGCATTACGGGTTTGCGAGCATGACTGCGCAGGTGACGGCGT
TGTATCCGGGATTCCTGGCGGCGGCGCTCGCGGGCGGCGTGCCGCCGATGATGGCAGCGCTGCCGCTGGCATATTTTTCG
AGCCTGAATGCGGCGATGACGCACTATGGCACCGGGTCGGCGCCGGTGTTTTTTGGAGCGGGGTATGTGCGGCAGGGTGA
GTGGTGGCGGTTGGGATTCCTGATATCCGTGGTAAATCTGGTGATCTGGCTGGGGATCGGGTCGCTGTGGTGGAAGCTGG
TGGGGATCTGGTAA

Upstream 100 bases:

>100_bases
GCGGATGTTTGCGGCGTGCGAGCAGACAAATGCACAGTACGGTGCGAGACAATGATGGCTCGTGGCGGAGAAAATAGAAC
ACTCATGGTGGCGGTGGGCG

Downstream 100 bases:

>100_bases
GAGTCTATGAAAATTGGAATCTGTGTGCTGGCAATGACGGCACTGGCTGGGACCATTCCTGGCGCCGAAGTGCAGTATTG
GATCGCGCCGTGCGCGAATT

Product: anion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLTAAKVLSGFGNVTVWLVFTAF
LFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLVLAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGS
FLMLVSFHTTYTASAMFLTGMAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREM
ARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWEDLLAEHRAWDALIWFAPLVMM
ADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYVHYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFS
SLNAAMTHYGTGSAPVFFGAGYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW

Sequences:

>Translated_457_residues
MVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLTAAKVLSGFGNVTVWLVFTAF
LFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLVLAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGS
FLMLVSFHTTYTASAMFLTGMAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREM
ARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWEDLLAEHRAWDALIWFAPLVMM
ADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYVHYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFS
SLNAAMTHYGTGSAPVFFGAGYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW
>Mature_457_residues
MVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLTAAKVLSGFGNVTVWLVFTAF
LFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLVLAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGS
FLMLVSFHTTYTASAMFLTGMAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREM
ARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWEDLLAEHRAWDALIWFAPLVMM
ADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYVHYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFS
SLNAAMTHYGTGSAPVFFGAGYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=461, Percent_Identity=34.2733188720174, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1786829, Length=471, Percent_Identity=31.6348195329087, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789444, Length=469, Percent_Identity=30.9168443496802, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 49409; Mature: 49409

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLT
CEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AAKVLSGFGNVTVWLVFTAFLFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEE
LAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGSFLMLVSFHTTYTASAMFLTG
EECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHC
MAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREM
CCCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWED
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAEHRAWDALIWFAPLVMMADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFSSLNAAMTHYGTGSAPVFFGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
GYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLT
CEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AAKVLSGFGNVTVWLVFTAFLFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEE
LAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGSFLMLVSFHTTYTASAMFLTG
EECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHEEEEHHHHHHHHHHHHHC
MAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREM
CCCCHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWED
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAEHRAWDALIWFAPLVMMADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFSSLNAAMTHYGTGSAPVFFGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
GYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]