| Definition | Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome. |
|---|---|
| Accession | NC_008536 |
| Length | 9,965,640 |
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The map label for this gene is fabG [H]
Identifier: 116623058
GI number: 116623058
Start: 5015771
End: 5016532
Strand: Direct
Name: fabG [H]
Synonym: Acid_3962
Alternate gene names: 116623058
Gene position: 5015771-5016532 (Clockwise)
Preceding gene: 116623054
Following gene: 116623059
Centisome position: 50.33
GC content: 63.91
Gene sequence:
>762_bases ATGATTCAGACTGAGGAGTTCGGAAACCAGACCGTCCTGATCACCGGCGCCAGCGCCGGCATCGGTGCCGCCGCCGCGCG GGCCTTCGGCAGCCGCGGAGCCCACGTCGTGGTCCACTACAACAGCCGGCGCGAAGCCGCCGGAGAGGTTGTGAAAGCCA TTCAGGCTGCCGGCGGCAGCGGAGAAATCGTCCAGGCGGACCTCGGCGCCGAAAGCGGAGTTCAGAGCCTCTGCGATTGG GCCCGCGCGCGCAAGATCGATATCCTGGTCAACAATGCGGGCTCCCTGGTGCGCCGCACCAAAGTCCTCGAGTTCACGCC GGAGTTGATGAACCAGGTGTTGCTGCTCAACTTCACCAGCGCCTTTTTTATCTCGCAGGCGGTGCTCGCCGGTATGGTCG AGCGCAGGCACGGCATCATCGTCAATATCTCCTCGGTAGCTGCGCGCTTTGGCGGCGGCATCGGAGCGCTCGCATATTCC GCCGCCAAGGCCGCGCTCTCTGCCATGACCAAAAATATGGCCAGGGAATTTGCGCCCGCCGGCATTCGCGTCAACGCGGT TTCCCCCGGCACAATCGATACCGATTATCACCGCGCCTTCTCCACCGAGCAGATGCTCAACAACACCAGGGCGGCCACGC CCGCCGGCCGGCTCGGCACATCCGAGGAAGTCGCCGACGCCATTCTGTTTCTCTGCTCCGATGGCGCGCGCTTCATTCAA GGACAGGCGCTCGAGGTCAACGGCGGATTCCTGATGGTGTGA
Upstream 100 bases:
>100_bases TCCTTGCAGCTCTGCAAAGGTTTGCAACTTCCAATCAATCAAGCTTTCTTGACTTTGCTTCCCGCCGGAGTGAAAATAGA AAACGTTTGCAAAAACCATC
Downstream 100 bases:
>100_bases CGATCGGCGAGAGTTGTGGCACGGGCGCCTGAGCCTCCTGCCCGGCGCTCGCGATGACCTACGCGAAAAACAGGAGAGCG CCCGCCCGCCACTATTGCTG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 253; Mature: 253
Protein sequence:
>253_residues MIQTEEFGNQTVLITGASAGIGAAAARAFGSRGAHVVVHYNSRREAAGEVVKAIQAAGGSGEIVQADLGAESGVQSLCDW ARARKIDILVNNAGSLVRRTKVLEFTPELMNQVLLLNFTSAFFISQAVLAGMVERRHGIIVNISSVAARFGGGIGALAYS AAKAALSAMTKNMAREFAPAGIRVNAVSPGTIDTDYHRAFSTEQMLNNTRAATPAGRLGTSEEVADAILFLCSDGARFIQ GQALEVNGGFLMV
Sequences:
>Translated_253_residues MIQTEEFGNQTVLITGASAGIGAAAARAFGSRGAHVVVHYNSRREAAGEVVKAIQAAGGSGEIVQADLGAESGVQSLCDW ARARKIDILVNNAGSLVRRTKVLEFTPELMNQVLLLNFTSAFFISQAVLAGMVERRHGIIVNISSVAARFGGGIGALAYS AAKAALSAMTKNMAREFAPAGIRVNAVSPGTIDTDYHRAFSTEQMLNNTRAATPAGRLGTSEEVADAILFLCSDGARFIQ GQALEVNGGFLMV >Mature_253_residues MIQTEEFGNQTVLITGASAGIGAAAARAFGSRGAHVVVHYNSRREAAGEVVKAIQAAGGSGEIVQADLGAESGVQSLCDW ARARKIDILVNNAGSLVRRTKVLEFTPELMNQVLLLNFTSAFFISQAVLAGMVERRHGIIVNISSVAARFGGGIGALAYS AAKAALSAMTKNMAREFAPAGIRVNAVSPGTIDTDYHRAFSTEQMLNNTRAATPAGRLGTSEEVADAILFLCSDGARFIQ GQALEVNGGFLMV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.6451612903226, Blast_Score=104, Evalue=8e-23, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=30.6772908366534, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=34.1176470588235, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=29.5275590551181, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=171, Percent_Identity=32.1637426900585, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=30.8943089430894, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.4655172413793, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=30.6513409961686, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=29.6875, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503301, Length=167, Percent_Identity=29.940119760479, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4557649, Length=195, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=29.3172690763052, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4504505, Length=258, Percent_Identity=29.8449612403101, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=31.25, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=30.6122448979592, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=40.1606425702811, Blast_Score=157, Evalue=7e-40, Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=35.9504132231405, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=37.1900826446281, Blast_Score=121, Evalue=6e-29, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=32.6693227091633, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=31.8548387096774, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=33.0612244897959, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=28.6919831223629, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787545, Length=90, Percent_Identity=41.1111111111111, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.1285140562249, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=32.0610687022901, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=31.3253012048193, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=34.3283582089552, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=32.9545454545455, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=31.4176245210728, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=31.6793893129771, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.8300395256917, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=33.457249070632, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=28.5171102661597, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=34.2007434944238, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=31.9548872180451, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=33.0827067669173, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=31.9548872180451, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=32.2751322751323, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=31.3131313131313, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=31.8548387096774, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=30.0395256916996, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=31.4814814814815, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.5454545454545, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=27.4074074074074, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=29.1457286432161, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.125, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=28.6245353159851, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.8973384030418, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17561272, Length=206, Percent_Identity=28.1553398058252, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI71997099, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=28.7128712871287, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=27.979274611399, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508651, Length=156, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=31.3807531380753, Blast_Score=92, Evalue=1e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=257, Percent_Identity=29.1828793774319, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=3e-13, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=37.3015873015873, Blast_Score=125, Evalue=3e-29, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=36.2204724409449, Blast_Score=123, Evalue=9e-29, Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=35.1351351351351, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=34.2307692307692, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=32.2448979591837, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=29.2, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.1740890688259, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=33.4615384615385, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=33.0049261083744, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21357673, Length=204, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI116007236, Length=244, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26444; Mature: 26444
Theoretical pI: Translated: 8.24; Mature: 8.24
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIQTEEFGNQTVLITGASAGIGAAAARAFGSRGAHVVVHYNSRREAAGEVVKAIQAAGGS CCCCCHHCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC GEIVQADLGAESGVQSLCDWARARKIDILVNNAGSLVRRTKVLEFTPELMNQVLLLNFTS CCEEEECCCCCCCHHHHHHHHHHCEEEEEEECCCHHHHHHHHHEECHHHHHHHHHHHHHH AFFISQAVLAGMVERRHGIIVNISSVAARFGGGIGALAYSAAKAALSAMTKNMAREFAPA HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC GIRVNAVSPGTIDTDYHRAFSTEQMLNNTRAATPAGRLGTSEEVADAILFLCSDGARFIQ CEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHC GQALEVNGGFLMV CEEEEECCCEEEC >Mature Secondary Structure MIQTEEFGNQTVLITGASAGIGAAAARAFGSRGAHVVVHYNSRREAAGEVVKAIQAAGGS CCCCCHHCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC GEIVQADLGAESGVQSLCDWARARKIDILVNNAGSLVRRTKVLEFTPELMNQVLLLNFTS CCEEEECCCCCCCHHHHHHHHHHCEEEEEEECCCHHHHHHHHHEECHHHHHHHHHHHHHH AFFISQAVLAGMVERRHGIIVNISSVAARFGGGIGALAYSAAKAALSAMTKNMAREFAPA HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC GIRVNAVSPGTIDTDYHRAFSTEQMLNNTRAATPAGRLGTSEEVADAILFLCSDGARFIQ CEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHC GQALEVNGGFLMV CEEEEECCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1556094; 8905232; 9278503; 1314802 [H]