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The map label for this gene is yoeB [H]

Identifier: 116623005

GI number: 116623005

Start: 4942489

End: 4942761

Strand: Direct

Name: yoeB [H]

Synonym: Acid_3909

Alternate gene names: 116623005

Gene position: 4942489-4942761 (Clockwise)

Preceding gene: 116623004

Following gene: 116623007

Centisome position: 49.6

GC content: 56.04

Gene sequence:

>273_bases
GTGAAGCGAGAGCGTAAACGGGTTGCGATCTTTCAACCTGAGTTCCGGGAGGATCTGCGTTTTTGGGGCAAAACGGAACG
AAGCGCCGCAATCAGAGTGCTGGATCTTATTGAAGCGGCCATGCGGGACCCCTTAGAAGGGCCGGGAAAACCCGAACCGC
TGAGATATTTACTGGCGGGGTGTTGGTCGCGCCGCGTCACTCAGGAACATCGCCTGGTCTACCGGGTCACGGACGAGGCC
ATTGATTTTCTCCAAGCTCGATATCACTACTGA

Upstream 100 bases:

>100_bases
TCACCACGCAACGCTCGACGTCTTCTGGGGGCGCTACGCCAAGCAGAACGTGGAAAAACGAAGCCCGAAACCGCATCGGA
ATTGAGGCGAGAGATCCTCG

Downstream 100 bases:

>100_bases
CGCGTTAGTCGGAATCCGCAGTGCTACGGCGTGTCGCGCAATACTGCCCAACAATCCGTTAGCTTCGGTTGACCCAAGGT
GTTCCGGATTGCCTGTTCAT

Product: addiction module antitoxin

Products: NA

Alternate protein names: Endoribonuclease YoeB; Putative mRNA interferase YoeB [H]

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MKRERKRVAIFQPEFREDLRFWGKTERSAAIRVLDLIEAAMRDPLEGPGKPEPLRYLLAGCWSRRVTQEHRLVYRVTDEA
IDFLQARYHY

Sequences:

>Translated_90_residues
MKRERKRVAIFQPEFREDLRFWGKTERSAAIRVLDLIEAAMRDPLEGPGKPEPLRYLLAGCWSRRVTQEHRLVYRVTDEA
IDFLQARYHY
>Mature_90_residues
MKRERKRVAIFQPEFREDLRFWGKTERSAAIRVLDLIEAAMRDPLEGPGKPEPLRYLLAGCWSRRVTQEHRLVYRVTDEA
IDFLQARYHY

Specific function: Part of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides [H]

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=81, Percent_Identity=45.679012345679, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10820; Mature: 10820

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRERKRVAIFQPEFREDLRFWGKTERSAAIRVLDLIEAAMRDPLEGPGKPEPLRYLLAG
CCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CWSRRVTQEHRLVYRVTDEAIDFLQARYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRERKRVAIFQPEFREDLRFWGKTERSAAIRVLDLIEAAMRDPLEGPGKPEPLRYLLAG
CCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CWSRRVTQEHRLVYRVTDEAIDFLQARYHY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]