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The map label for this gene is lsrG [H]

Identifier: 116622992

GI number: 116622992

Start: 4925354

End: 4925659

Strand: Direct

Name: lsrG [H]

Synonym: Acid_3895

Alternate gene names: 116622992

Gene position: 4925354-4925659 (Clockwise)

Preceding gene: 116622990

Following gene: 116622993

Centisome position: 49.42

GC content: 62.75

Gene sequence:

>306_bases
ATGCAGATCCTCATCGTCCACGCCCACGTCAAACCCGAATTCATCGACGCCTTCAAGGCCGCCACCACGATCAACGCCAA
GAACAGCGCCCGGGAACCCGGCATCGCCCGCTTCGAACTCCTCCAACAGCAGGACGACCCGTCTCGCTTCGTCCTGGTCG
AGGTCTACCGCGACGCCGACGCCCCCGCCAAACACAAGGCCACCGCGCACTACAACACCTGGATCGAAACCGTGAACGAT
ATGTTCGTCACCCCGCGCACCCGCGCCTTCTACACCAACATCTCCCCGCCCGATGCCGCCTTCTAA

Upstream 100 bases:

>100_bases
GCGCTGCTTGACGTGTTCTTCGCGTTACTCTGCGGCTCTGCGTCTCTGCGAGAAATATTTCCCTCATCCCCCGCGAGCCC
CCTCTTATTACAATGAAGCG

Downstream 100 bases:

>100_bases
CTTCGAATTCGCCACCGCCGGCCGCATCCTCTTCGGCGAAGCCGTTGTCCGCGACGTCCCCGCCGCCGCCCGCGCCTTCG
GCGCCAGCGCACTCTTCGTC

Product: antibiotic biosynthesis monooxygenase

Products: NA

Alternate protein names: AI-2-degrading protein lsrG [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MQILIVHAHVKPEFIDAFKAATTINAKNSAREPGIARFELLQQQDDPSRFVLVEVYRDADAPAKHKATAHYNTWIETVND
MFVTPRTRAFYTNISPPDAAF

Sequences:

>Translated_101_residues
MQILIVHAHVKPEFIDAFKAATTINAKNSAREPGIARFELLQQQDDPSRFVLVEVYRDADAPAKHKATAHYNTWIETVND
MFVTPRTRAFYTNISPPDAAF
>Mature_101_residues
MQILIVHAHVKPEFIDAFKAATTINAKNSAREPGIARFELLQQQDDPSRFVLVEVYRDADAPAKHKATAHYNTWIETVND
MFVTPRTRAFYTNISPPDAAF

Specific function: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another

COG id: COG1359

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lsrG family [H]

Homologues:

Organism=Escherichia coli, GI1787797, Length=96, Percent_Identity=32.2916666666667, Blast_Score=63, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007138
- InterPro:   IPR011008 [H]

Pfam domain/function: PF03992 ABM [H]

EC number: NA

Molecular weight: Translated: 11459; Mature: 11459

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILIVHAHVKPEFIDAFKAATTINAKNSAREPGIARFELLQQQDDPSRFVLVEVYRDAD
CEEEEEEECCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
APAKHKATAHYNTWIETVNDMFVTPRTRAFYTNISPPDAAF
CCCCCCCCCHHHHHHHHHHCEECCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MQILIVHAHVKPEFIDAFKAATTINAKNSAREPGIARFELLQQQDDPSRFVLVEVYRDAD
CEEEEEEECCCCHHHHHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
APAKHKATAHYNTWIETVNDMFVTPRTRAFYTNISPPDAAF
CCCCCCCCCHHHHHHHHHHCEECCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA