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The map label for this gene is gph [C]

Identifier: 116622951

GI number: 116622951

Start: 4887432

End: 4888094

Strand: Reverse

Name: gph [C]

Synonym: Acid_3853

Alternate gene names: 116622951

Gene position: 4888094-4887432 (Counterclockwise)

Preceding gene: 116622952

Following gene: 116622950

Centisome position: 49.05

GC content: 58.82

Gene sequence:

>663_bases
ATGAAGAAACTCATCGTATTCGACATGGATGGCGTCCTGGTGGACGTCACCGAAAGCTATCGCGAAAGCATCGCGCAGAC
CGTGACGCATTTCACCGGCCACGCGCCCACACGCGAACAGATTCAGCAGTTCAAAAACCAGGGCGGCTGGAATGACGATT
GGAAACTCTCTCACCACATCTGCTCTAAACTCGGCTGCGACGCCACCTTCGAAACCGTGAAAGAGTATTTCCAATCCATC
TTCCTCGGCACTGCCAACGACGGCCTGATCCTTCGCGAGCAGTGGGTCGCGCGTCCTGGCACGCTCGAAAAGCTCTCCTC
GAATTTCGATTTCGCCGTCTTCACCGGACGCCCACGCTCCGACGCCAAGATCACACTCGATCGGTTCGCCGCCGGACTGA
ACTTCGCGCCCGTGATCGGCATGGAAGACGTGCTCCACCACAAGCCGCATCCCGAAGGACTGCTCCAATTGCCGCAGACC
GCCTTCTACGTCGGCGATACGGTGGATGACGCACGCTGCGCGCGCGCCGCCAAGGTCCCGTTCATCGGCATCGCCGCGCC
ATCCAACCCGCTCTATATAGACCTCGTTTTCCTGTTCCAGGAAGAGGGCGCCTACGCCATCATCGACGACATCAACTATC
TCGAGGAGGTCTTCACCGCATGA

Upstream 100 bases:

>100_bases
GCGACCGCAGCTACGAAGCCGCCGGCTGCGTCCGCATCACGGTCGGCACCCGCGAGCAGACGCGCCGCCTGCTCACCGCC
CTCGAAGGGATCTGGAACCA

Downstream 100 bases:

>100_bases
GATCCGCCACCATTCAGCGCGATACCAAAGAGACGCGAATCGGCGGCACGCTCAAACTCGAAGGTCGCGGCCGCTACGAG
ATCGCGACCGGCATTCGCTT

Product: HAD family hydrolase

Products: 3-(imidazol-4-yl)-2-oxopropyl phosphate; H2O

Alternate protein names: HAD Superfamily Hydrolase; HAD Family Hydrolase; HAD Superfamily Hydrolase TIGR; HAD Superfamily Phosphatase; Phosphoglycolate Phosphatase

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKKLIVFDMDGVLVDVTESYRESIAQTVTHFTGHAPTREQIQQFKNQGGWNDDWKLSHHICSKLGCDATFETVKEYFQSI
FLGTANDGLILREQWVARPGTLEKLSSNFDFAVFTGRPRSDAKITLDRFAAGLNFAPVIGMEDVLHHKPHPEGLLQLPQT
AFYVGDTVDDARCARAAKVPFIGIAAPSNPLYIDLVFLFQEEGAYAIIDDINYLEEVFTA

Sequences:

>Translated_220_residues
MKKLIVFDMDGVLVDVTESYRESIAQTVTHFTGHAPTREQIQQFKNQGGWNDDWKLSHHICSKLGCDATFETVKEYFQSI
FLGTANDGLILREQWVARPGTLEKLSSNFDFAVFTGRPRSDAKITLDRFAAGLNFAPVIGMEDVLHHKPHPEGLLQLPQT
AFYVGDTVDDARCARAAKVPFIGIAAPSNPLYIDLVFLFQEEGAYAIIDDINYLEEVFTA
>Mature_220_residues
MKKLIVFDMDGVLVDVTESYRESIAQTVTHFTGHAPTREQIQQFKNQGGWNDDWKLSHHICSKLGCDATFETVKEYFQSI
FLGTANDGLILREQWVARPGTLEKLSSNFDFAVFTGRPRSDAKITLDRFAAGLNFAPVIGMEDVLHHKPHPEGLLQLPQT
AFYVGDTVDDARCARAAKVPFIGIAAPSNPLYIDLVFLFQEEGAYAIIDDINYLEEVFTA

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.19

Molecular weight: Translated: 24645; Mature: 24645

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIVFDMDGVLVDVTESYRESIAQTVTHFTGHAPTREQIQQFKNQGGWNDDWKLSHHI
CCEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
CSKLGCDATFETVKEYFQSIFLGTANDGLILREQWVARPGTLEKLSSNFDFAVFTGRPRS
HHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCHHHHHCCCCEEEEECCCCC
DAKITLDRFAAGLNFAPVIGMEDVLHHKPHPEGLLQLPQTAFYVGDTVDDARCARAAKVP
CCEEEHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHHHHHCCCC
FIGIAAPSNPLYIDLVFLFQEEGAYAIIDDINYLEEVFTA
EEEEECCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHCC
>Mature Secondary Structure
MKKLIVFDMDGVLVDVTESYRESIAQTVTHFTGHAPTREQIQQFKNQGGWNDDWKLSHHI
CCEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
CSKLGCDATFETVKEYFQSIFLGTANDGLILREQWVARPGTLEKLSSNFDFAVFTGRPRS
HHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCCCHHHHHCCCCEEEEECCCCC
DAKITLDRFAAGLNFAPVIGMEDVLHHKPHPEGLLQLPQTAFYVGDTVDDARCARAAKVP
CCEEEHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHHHHHCCCC
FIGIAAPSNPLYIDLVFLFQEEGAYAIIDDINYLEEVFTA
EEEEECCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate

Specific reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA