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The map label for this gene is macB [H]

Identifier: 116622936

GI number: 116622936

Start: 4870157

End: 4872763

Strand: Reverse

Name: macB [H]

Synonym: Acid_3838

Alternate gene names: 116622936

Gene position: 4872763-4870157 (Counterclockwise)

Preceding gene: 116622937

Following gene: 116622931

Centisome position: 48.9

GC content: 68.32

Gene sequence:

>2607_bases
ATGAACTGGGAAGATCGACTCGATAAGGAGCTGCGATTTCATCTGGAACAGCACACCGCCGATCTGATCGCGCAGGGGCA
CACACCCGATGCGGCGCGGCGGATCGCGCGGATCGCGCTGGGTGGACCGGACCAGGTGAAGGAGGGATGCCGGGACGAGC
GCCCCGCGCGCTGGCTGGCGGATTTCTGGCAGGACGTGCGATATGCGGTGCGCAGCCTGCGGCAGCGGCCCGGGTTCACG
GCGGTTGCCCTGGGGACGCTGGCGCTCGGCATCGGCGCCACAACAGTGATGTTTACACTCATTAACGGCGTACTGCTGAA
GCCGCTGCCGTACTCCGACCCGGGCCGGTTGATCCAGGTGGCGGGACACACAGCTCAGTACGGGAATCAGAATTTCGCGT
ACCCGGACTACCTGGATCTGCGGCGCGAAATTCAGTCGTTAGGTCCGCTGGCGGGCTGGGTCTACAACTGGGGAACGCTG
AGCCAGCCGGGCGATCCGGAGAATGTGGAAGTACGCGAGGTCACGGCGGATCTTTTCCCGGTGCTGGGTGCGAAGATGCT
GCGCGGCCGCGGATTTCTGCCCGAGGAAGATGCTCCCGGGGGACGGCCGGTGGCGATTCTCGGCTACAGCCTGTGGCAGC
GGAAGTTCGCGGGGAGCGCGGAGGCGATTGACGCGCCAGTGGTGCTGGACGGAACGCGGTATACGGTGGTGGGAATCGCC
CGGCCGGAGATGCGGCTCGAGGGAGAGCCGGATGTTTTCACGCCACTCGGACAGGACCCGGCGGCTTACCTGCGCAACCG
GCGGGCGCATCCGGTGGGTGTGCTGGGACGGTTGCGGCCGGGGGTAACACTGGCGCAGGCGCAATCCGAGGTAGCGGTGC
TCGCCGGCAGGCTGTCTGCGCAATATCCGGAGAGCAATAAGGATCGCGCTTTTGTGGCGGACCGCCTGAGGGCCGACGTG
GGCGACGTGCAATCCACGCTCTGGCTGTTGTTGGGCGCGGTGACGCTGGTGCTGTTGATTGCGTGCGTGAATGTGGCGAG
CCTGCTGCTGGCGAAGGCGGTGGCGCGCGAGCGCGAGCTGGCGATGCGGATGGCGCTGGGCGCGGGCCGCTGGCGGCTGG
TGCGGCAATGCCTCACGGAGAGCGCGGTGCTCGGGTTTGCGGGCGGCGTGGTCGGGGTGGTGCTGGCGGCGGTGGGGATC
CGGCCGTTCGTCGCATTCTGGCCGGGGAGTTTGCCGCGCGCCGAGGAAGTGCAGTTGGATTGGCGGGTGCTGCTGTTCGC
GGTGGCGGCGTCGCTGGTCAGCGGAATTCTGTTCGGGCTGGCGCCGGCACTGCGCGCGCCGGTTCGTCAACTGGAGCAGG
CGCTGCGCAGTGGGGGACGCGCAGTGGCGGGCAGTCCACGGCGGCTGCACGGAGGGTTCGTGGCGGCCGAGATCGCGCTC
GCGGTGGTGCTGCTGGTGGCGGCGGGGATGTTGGGACGCACGCTGATGAATCTCGCGGCGCTCGAGCCCGGAGTGAACCT
GCACAACGTGCTGGTCGCGCGCATGCGTCTGGCGCCTTCGACCGTGTCCAGTCCGGCGGCGATGCGCGCGGCGTGGCAGT
CCGCGCTGGATGAGGCGCGGCGCGTGCCGGGCGTGCAGGCGGCCGCGACGGTGGATACCGTGCCGATGCGGCAGGGCAAC
AATCAACTGGGTTATTGGACTTCGGCCGCCATGCCGGAGGCGAGGCAGCTGCCACTGGCGCTGGCGACGAGCGTCACGCC
GGATTACCTGAAGGTGATGGGGATCGCGCTGCAGCACGGACGCTTCTTCGACGAGCATGACCGGCTGGACAGTGAGCTGG
TGGTGGCGATCGACGACGTGATGGCGAAGCAGGCATTCCGAGGCGACGACCCAATCGGCAAGCGCCTGTGGATCCCGGAT
ATGAGCGCGGGTCCGGTACGGGTGGTCGGCGTGGTGGGGCATGTGCGGCATTGGGGACTGGCGGGCGATGACCAGGCCAA
GGTGCGCGCGCAGGTGTACTATCCCTTCGCGCAGGTGCCGGACCGGCTGGTGCGGCGGTGGTCGGAATTGATGTCAGTGG
CGGTGAGGACGAACGTGCCGCCGTTGGGCGTGGTAGAGCCGCTGCGGCGCGCGGTGAGGGGCGCTGGGGGCGACCAGGTG
CTGTACCAGGTGCGCACGATGGAGCAACTGGCGCAAAGTTCGATCGGGCGGCAGCGATTCCTGATGCTGCTCTTCGGCAT
CTTCGCGATGCTGGCGCTGGCCCTGGCATCGATCGGGATTTACGGTGTGCTGGCGTATTTGACGCGGCAGCGGGTGCCGG
AGATCGGGATGCGGATGGCGCTCGGGGCGACTTCGCGCGATGTGATCGGAATGGTGCTGCGGCAGAGCCTTGGGATGATC
GCGGCTGGGGTTGTGGTCGGATTGGCGGCGGCACTGGCGATGCGGCGCGTGTTGGAGCGGCTGGTGGAGGGGATGAGGCC
GATGGATCCGGTGACGGTGGCCTTGATGATCGGCGTGCTGGTGGCGGCGGCGCTGGCGGCGAGCTTCGTGCCGGCACTCA
GGGCGAGCAGGGTGGACCCGATGGCGGCGCTGCGTGCGGAGAGGTGA

Upstream 100 bases:

>100_bases
ACTCGGAAGGGGCGCGGCCAGCTGGAGACGGAGACGGCGAGTTGGGAGCGGCTTGCCGAGGCCGTGGGACTCATCCTTAG
ACTGACCGGGGAGGCGTGAG

Downstream 100 bases:

>100_bases
GGTCGCCGAGTGCAGCACGGTCGAAAACCCCACTGCTCCGAAGAGAGATGGGCAACCAGGAATCGCGAGATCGCTCCCTT
TACGCAAGGCGTGAAAACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 868; Mature: 868

Protein sequence:

>868_residues
MNWEDRLDKELRFHLEQHTADLIAQGHTPDAARRIARIALGGPDQVKEGCRDERPARWLADFWQDVRYAVRSLRQRPGFT
AVALGTLALGIGATTVMFTLINGVLLKPLPYSDPGRLIQVAGHTAQYGNQNFAYPDYLDLRREIQSLGPLAGWVYNWGTL
SQPGDPENVEVREVTADLFPVLGAKMLRGRGFLPEEDAPGGRPVAILGYSLWQRKFAGSAEAIDAPVVLDGTRYTVVGIA
RPEMRLEGEPDVFTPLGQDPAAYLRNRRAHPVGVLGRLRPGVTLAQAQSEVAVLAGRLSAQYPESNKDRAFVADRLRADV
GDVQSTLWLLLGAVTLVLLIACVNVASLLLAKAVARERELAMRMALGAGRWRLVRQCLTESAVLGFAGGVVGVVLAAVGI
RPFVAFWPGSLPRAEEVQLDWRVLLFAVAASLVSGILFGLAPALRAPVRQLEQALRSGGRAVAGSPRRLHGGFVAAEIAL
AVVLLVAAGMLGRTLMNLAALEPGVNLHNVLVARMRLAPSTVSSPAAMRAAWQSALDEARRVPGVQAAATVDTVPMRQGN
NQLGYWTSAAMPEARQLPLALATSVTPDYLKVMGIALQHGRFFDEHDRLDSELVVAIDDVMAKQAFRGDDPIGKRLWIPD
MSAGPVRVVGVVGHVRHWGLAGDDQAKVRAQVYYPFAQVPDRLVRRWSELMSVAVRTNVPPLGVVEPLRRAVRGAGGDQV
LYQVRTMEQLAQSSIGRQRFLMLLFGIFAMLALALASIGIYGVLAYLTRQRVPEIGMRMALGATSRDVIGMVLRQSLGMI
AAGVVVGLAAALAMRRVLERLVEGMRPMDPVTVALMIGVLVAAALAASFVPALRASRVDPMAALRAER

Sequences:

>Translated_868_residues
MNWEDRLDKELRFHLEQHTADLIAQGHTPDAARRIARIALGGPDQVKEGCRDERPARWLADFWQDVRYAVRSLRQRPGFT
AVALGTLALGIGATTVMFTLINGVLLKPLPYSDPGRLIQVAGHTAQYGNQNFAYPDYLDLRREIQSLGPLAGWVYNWGTL
SQPGDPENVEVREVTADLFPVLGAKMLRGRGFLPEEDAPGGRPVAILGYSLWQRKFAGSAEAIDAPVVLDGTRYTVVGIA
RPEMRLEGEPDVFTPLGQDPAAYLRNRRAHPVGVLGRLRPGVTLAQAQSEVAVLAGRLSAQYPESNKDRAFVADRLRADV
GDVQSTLWLLLGAVTLVLLIACVNVASLLLAKAVARERELAMRMALGAGRWRLVRQCLTESAVLGFAGGVVGVVLAAVGI
RPFVAFWPGSLPRAEEVQLDWRVLLFAVAASLVSGILFGLAPALRAPVRQLEQALRSGGRAVAGSPRRLHGGFVAAEIAL
AVVLLVAAGMLGRTLMNLAALEPGVNLHNVLVARMRLAPSTVSSPAAMRAAWQSALDEARRVPGVQAAATVDTVPMRQGN
NQLGYWTSAAMPEARQLPLALATSVTPDYLKVMGIALQHGRFFDEHDRLDSELVVAIDDVMAKQAFRGDDPIGKRLWIPD
MSAGPVRVVGVVGHVRHWGLAGDDQAKVRAQVYYPFAQVPDRLVRRWSELMSVAVRTNVPPLGVVEPLRRAVRGAGGDQV
LYQVRTMEQLAQSSIGRQRFLMLLFGIFAMLALALASIGIYGVLAYLTRQRVPEIGMRMALGATSRDVIGMVLRQSLGMI
AAGVVVGLAAALAMRRVLERLVEGMRPMDPVTVALMIGVLVAAALAASFVPALRASRVDPMAALRAER
>Mature_868_residues
MNWEDRLDKELRFHLEQHTADLIAQGHTPDAARRIARIALGGPDQVKEGCRDERPARWLADFWQDVRYAVRSLRQRPGFT
AVALGTLALGIGATTVMFTLINGVLLKPLPYSDPGRLIQVAGHTAQYGNQNFAYPDYLDLRREIQSLGPLAGWVYNWGTL
SQPGDPENVEVREVTADLFPVLGAKMLRGRGFLPEEDAPGGRPVAILGYSLWQRKFAGSAEAIDAPVVLDGTRYTVVGIA
RPEMRLEGEPDVFTPLGQDPAAYLRNRRAHPVGVLGRLRPGVTLAQAQSEVAVLAGRLSAQYPESNKDRAFVADRLRADV
GDVQSTLWLLLGAVTLVLLIACVNVASLLLAKAVARERELAMRMALGAGRWRLVRQCLTESAVLGFAGGVVGVVLAAVGI
RPFVAFWPGSLPRAEEVQLDWRVLLFAVAASLVSGILFGLAPALRAPVRQLEQALRSGGRAVAGSPRRLHGGFVAAEIAL
AVVLLVAAGMLGRTLMNLAALEPGVNLHNVLVARMRLAPSTVSSPAAMRAAWQSALDEARRVPGVQAAATVDTVPMRQGN
NQLGYWTSAAMPEARQLPLALATSVTPDYLKVMGIALQHGRFFDEHDRLDSELVVAIDDVMAKQAFRGDDPIGKRLWIPD
MSAGPVRVVGVVGHVRHWGLAGDDQAKVRAQVYYPFAQVPDRLVRRWSELMSVAVRTNVPPLGVVEPLRRAVRGAGGDQV
LYQVRTMEQLAQSSIGRQRFLMLLFGIFAMLALALASIGIYGVLAYLTRQRVPEIGMRMALGATSRDVIGMVLRQSLGMI
AAGVVVGLAAALAMRRVLERLVEGMRPMDPVTVALMIGVLVAAALAASFVPALRASRVDPMAALRAER

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=314, Percent_Identity=23.5668789808917, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 93850; Mature: 93850

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWEDRLDKELRFHLEQHTADLIAQGHTPDAARRIARIALGGPDQVKEGCRDERPARWLA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
DFWQDVRYAVRSLRQRPGFTAVALGTLALGIGATTVMFTLINGVLLKPLPYSDPGRLIQV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
AGHTAQYGNQNFAYPDYLDLRREIQSLGPLAGWVYNWGTLSQPGDPENVEVREVTADLFP
CCCHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VLGAKMLRGRGFLPEEDAPGGRPVAILGYSLWQRKFAGSAEAIDAPVVLDGTRYTVVGIA
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHCCCCEEECCCEEEEEEEE
RPEMRLEGEPDVFTPLGQDPAAYLRNRRAHPVGVLGRLRPGVTLAQAQSEVAVLAGRLSA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
QYPESNKDRAFVADRLRADVGDVQSTLWLLLGAVTLVLLIACVNVASLLLAKAVAREREL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRMALGAGRWRLVRQCLTESAVLGFAGGVVGVVLAAVGIRPFVAFWPGSLPRAEEVQLD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
WRVLLFAVAASLVSGILFGLAPALRAPVRQLEQALRSGGRAVAGSPRRLHGGFVAAEIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHCHHHHHHHHH
AVVLLVAAGMLGRTLMNLAALEPGVNLHNVLVARMRLAPSTVSSPAAMRAAWQSALDEAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RVPGVQAAATVDTVPMRQGNNQLGYWTSAAMPEARQLPLALATSVTPDYLKVMGIALQHG
HCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCC
RFFDEHDRLDSELVVAIDDVMAKQAFRGDDPIGKRLWIPDMSAGPVRVVGVVGHVRHWGL
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHCCC
AGDDQAKVRAQVYYPFAQVPDRLVRRWSELMSVAVRTNVPPLGVVEPLRRAVRGAGGDQV
CCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHH
LYQVRTMEQLAQSSIGRQRFLMLLFGIFAMLALALASIGIYGVLAYLTRQRVPEIGMRMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LGATSRDVIGMVLRQSLGMIAAGVVVGLAAALAMRRVLERLVEGMRPMDPVTVALMIGVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VAAALAASFVPALRASRVDPMAALRAER
HHHHHHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MNWEDRLDKELRFHLEQHTADLIAQGHTPDAARRIARIALGGPDQVKEGCRDERPARWLA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
DFWQDVRYAVRSLRQRPGFTAVALGTLALGIGATTVMFTLINGVLLKPLPYSDPGRLIQV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
AGHTAQYGNQNFAYPDYLDLRREIQSLGPLAGWVYNWGTLSQPGDPENVEVREVTADLFP
CCCHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VLGAKMLRGRGFLPEEDAPGGRPVAILGYSLWQRKFAGSAEAIDAPVVLDGTRYTVVGIA
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHCCCCEEECCCEEEEEEEE
RPEMRLEGEPDVFTPLGQDPAAYLRNRRAHPVGVLGRLRPGVTLAQAQSEVAVLAGRLSA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
QYPESNKDRAFVADRLRADVGDVQSTLWLLLGAVTLVLLIACVNVASLLLAKAVAREREL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRMALGAGRWRLVRQCLTESAVLGFAGGVVGVVLAAVGIRPFVAFWPGSLPRAEEVQLD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
WRVLLFAVAASLVSGILFGLAPALRAPVRQLEQALRSGGRAVAGSPRRLHGGFVAAEIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHCHHHHHHHHH
AVVLLVAAGMLGRTLMNLAALEPGVNLHNVLVARMRLAPSTVSSPAAMRAAWQSALDEAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
RVPGVQAAATVDTVPMRQGNNQLGYWTSAAMPEARQLPLALATSVTPDYLKVMGIALQHG
HCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCC
RFFDEHDRLDSELVVAIDDVMAKQAFRGDDPIGKRLWIPDMSAGPVRVVGVVGHVRHWGL
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHCCC
AGDDQAKVRAQVYYPFAQVPDRLVRRWSELMSVAVRTNVPPLGVVEPLRRAVRGAGGDQV
CCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHH
LYQVRTMEQLAQSSIGRQRFLMLLFGIFAMLALALASIGIYGVLAYLTRQRVPEIGMRMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LGATSRDVIGMVLRQSLGMIAAGVVVGLAAALAMRRVLERLVEGMRPMDPVTVALMIGVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VAAALAASFVPALRASRVDPMAALRAER
HHHHHHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA