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The map label for this gene is yclJ [H]

Identifier: 116622737

GI number: 116622737

Start: 4603753

End: 4604505

Strand: Reverse

Name: yclJ [H]

Synonym: Acid_3636

Alternate gene names: 116622737

Gene position: 4604505-4603753 (Counterclockwise)

Preceding gene: 116622740

Following gene: 116622736

Centisome position: 46.2

GC content: 64.14

Gene sequence:

>753_bases
GTGTGTGAAGGCCGCGATTGCGTTACAACTAAAGCAGAAGAAGTGAGTACAACCGACACCACCACCGCGCGACGCTCCAT
CCTCTTAGTAGAGGACGATACTGAGCTCACGTCATTAATGACCGATTATTTCGCGCAGCACGGCTTCCAGGTCGAAGCGG
CCCACGATGGGCGCACCGGCCTGGCGCGCGCCATCGAAGGCTCGTTCGACCTGATCATCCTCGATGTGATGCTGCCCGTG
CTCGATGGGTTCGAAGTTTTGCGCCAGCTTCGCAAACGCAGCGCCACGCCGGTGATCATGCTCACCGCGCGCATCAGCCA
GAGTGACCGCGTGGCCGGCCTTAACTCCGGCGCCGACGATTACCTGCCCAAGCCCTTCGGTCCCGACGAACTGCTGGCGC
GCATTCGCGCCGTGCTGCGCCGCACCGGCCACACCGATGCCGCGCCGCCGCAGATCGTGGAATCGGCGGGCCTGCGCATC
GACCCCGCGGCGCGCGCGGTTTGGGATCACGGCGAGGCCATCGAGATCACTTCCATCGAATTCGACATCCTGGAGATTCT
GGTGCGCTCGGCGGGACGCACGGTGACCCGCGACGAACTCACCGCGGTCCTCTACCAGCGGCCCGCGACTCCTTACGAGC
GCTCGCTCGATGTCCACATCAGCCACCTGCGCAAGAAGCTCGAGCGCGACGATCGCTCCGTGATCCGCACCATCCGCGGC
GTCGGCTATCAATTCATGGCGGGTGAGCGATGA

Upstream 100 bases:

>100_bases
CTGCCGTGCATGCGGCGATCCAGTTCCGTTTCATCATATCCAGTAGACCGCAAACCACCCTCGCACCATCCTTAAGTTTT
GTAAAAGGCCCCCTGCGAAC

Downstream 100 bases:

>100_bases
AGGTCTATACCAAAGTTCTTCTCTGGTGCTTCGGCACGCTGCTGCTTTCCCTGATCGCTTTCGGCGGCGTCTCCTACGTC
TCGATGCGCAGCGTGGATCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MCEGRDCVTTKAEEVSTTDTTTARRSILLVEDDTELTSLMTDYFAQHGFQVEAAHDGRTGLARAIEGSFDLIILDVMLPV
LDGFEVLRQLRKRSATPVIMLTARISQSDRVAGLNSGADDYLPKPFGPDELLARIRAVLRRTGHTDAAPPQIVESAGLRI
DPAARAVWDHGEAIEITSIEFDILEILVRSAGRTVTRDELTAVLYQRPATPYERSLDVHISHLRKKLERDDRSVIRTIRG
VGYQFMAGER

Sequences:

>Translated_250_residues
MCEGRDCVTTKAEEVSTTDTTTARRSILLVEDDTELTSLMTDYFAQHGFQVEAAHDGRTGLARAIEGSFDLIILDVMLPV
LDGFEVLRQLRKRSATPVIMLTARISQSDRVAGLNSGADDYLPKPFGPDELLARIRAVLRRTGHTDAAPPQIVESAGLRI
DPAARAVWDHGEAIEITSIEFDILEILVRSAGRTVTRDELTAVLYQRPATPYERSLDVHISHLRKKLERDDRSVIRTIRG
VGYQFMAGER
>Mature_250_residues
MCEGRDCVTTKAEEVSTTDTTTARRSILLVEDDTELTSLMTDYFAQHGFQVEAAHDGRTGLARAIEGSFDLIILDVMLPV
LDGFEVLRQLRKRSATPVIMLTARISQSDRVAGLNSGADDYLPKPFGPDELLARIRAVLRRTGHTDAAPPQIVESAGLRI
DPAARAVWDHGEAIEITSIEFDILEILVRSAGRTVTRDELTAVLYQRPATPYERSLDVHISHLRKKLERDDRSVIRTIRG
VGYQFMAGER

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=43.8053097345133, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.4736842105263, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=40.0881057268723, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=38.9380530973451, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=40.1785714285714, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.8649789029536, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=37.1681415929204, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=36.697247706422, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=38.2222222222222, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=37.3333333333333, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.4841628959276, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=33.0396475770925, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=33.6244541484716, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=32.3275862068966, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.036036036036, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=130, Percent_Identity=33.8461538461538, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=31.6239316239316, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27815; Mature: 27815

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEGRDCVTTKAEEVSTTDTTTARRSILLVEDDTELTSLMTDYFAQHGFQVEAAHDGRTG
CCCCCCCCCCCHHHCCCCCCHHHHEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHH
LARAIEGSFDLIILDVMLPVLDGFEVLRQLRKRSATPVIMLTARISQSDRVAGLNSGADD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCC
YLPKPFGPDELLARIRAVLRRTGHTDAAPPQIVESAGLRIDPAARAVWDHGEAIEITSIE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEECHHHHHHHCCCCEEEEEECH
FDILEILVRSAGRTVTRDELTAVLYQRPATPYERSLDVHISHLRKKLERDDRSVIRTIRG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGYQFMAGER
CCCCCCCCCC
>Mature Secondary Structure
MCEGRDCVTTKAEEVSTTDTTTARRSILLVEDDTELTSLMTDYFAQHGFQVEAAHDGRTG
CCCCCCCCCCCHHHCCCCCCHHHHEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHH
LARAIEGSFDLIILDVMLPVLDGFEVLRQLRKRSATPVIMLTARISQSDRVAGLNSGADD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCC
YLPKPFGPDELLARIRAVLRRTGHTDAAPPQIVESAGLRIDPAARAVWDHGEAIEITSIE
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEECHHHHHHHCCCCEEEEEECH
FDILEILVRSAGRTVTRDELTAVLYQRPATPYERSLDVHISHLRKKLERDDRSVIRTIRG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGYQFMAGER
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]