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The map label for this gene is cefD [H]

Identifier: 116622552

GI number: 116622552

Start: 4363740

End: 4365005

Strand: Reverse

Name: cefD [H]

Synonym: Acid_3450

Alternate gene names: 116622552

Gene position: 4365005-4363740 (Counterclockwise)

Preceding gene: 116622554

Following gene: 116622551

Centisome position: 43.8

GC content: 63.82

Gene sequence:

>1266_bases
ATGGAACGCCGCCGTCTGCTCCATCTCGCCGCTGCCGCCGCTTTTCAGAGCCACGCCTTGGAGCGGGTACGAGCCGCCGC
GAGCGCTGCCGGCGCGCGCACTCCCGAGGAGATCGCAGCCGATGAGGATTTCTGGAGCGAGATCCGCTCCGCCTTCAGCA
TCGACCGCAACATCGTCAACTTCAACAACGGCTACGTCAGCCCCTCCCCGCGCCCCGTGCAGGACGCGATGCGCCGGTAT
CTCGAATACACCGACATGGGCCCGTATCACACCATGGTCGCCACGCTCGAGCACCAGGTGGAAGCCGTGCGCCGCCACCT
CGCGCAGGCCGCCGGGTGCGATGCCGAGGAGATGGCGATCACGCGCAACGCCAGCGAGGCGCTGGAGAACGCGCAGTATG
GCATCGACCTCAAACCCGGCGACGAAGTCCTCACCACGGACCAGGACTATCCGCGCATGCTGACCACATACGCGCAGCGC
GAACGACGCGAAGGCATCGTCCTCAAGACGATTTCTTTCCCCGTGCCGCCGCCCTCGATGGACGATCTCTACCGCCGCTT
CGAGCAGGCCGTTACGCCGCGCACGAAGATCATTCACTTCTGCCACATCACCAACCGCACAGGCCAGATTTTTCCGGTGC
GGAAGATTTGCCGGATGGCGCGGGCGCGCAACATCGCGACCATCGTGGATGGCGCGCACGCGTTCAGCCACTTCCCCTAC
AAAATCTCCGACCTGGAGTGCGACTACTACGGCACCAGCCTGCACAAGTGGACCTATGCGCCGATCGGCACCGGCTTCCT
GTATGTGCGCAAGAGCCGGATCGCCGGAACGTGGAGCATGATGGCGAGCGATAAGACGCAGGCCGGCGACATCCGCAAGT
TCGAAGAGATCGGTACCCATCCTGCGGCCAATCACAACGCCATCAGCGAGGCCCTGGTGTTCAATCAGAACCTGGGCATT
GATCGCAAGGCCGCGCGCCTGCGCTACCTGCGCGATCGCTGGGCTCTGCGTCTGGCGCGTAACCCCAAGTGCCGCATTCT
GCACAGCCCGGACCCGGAGCAATCCTGCGGGATCGGCTTCCTGGCCTTCGCCCCGGGAATCGACGCGGGCAAGATGCGCG
AAGCCTTGTGGGGCAAGTACAACATCATCACGACGTACATGCCGCACACCGAGTACAGCGGCCTGCGCGTAACCCCGAAC
ATCTACAGCACGCTCGGTGAAGTCGATTTCTTCGCCGACATGGTGGAGAAGGAATTGGCCTCGTAG

Upstream 100 bases:

>100_bases
CGTTTCGGCGTTTAAGCCGGCGGCGGTTACCCTTTTCCGCCGCCGGCTCTTTTTTTGCGCGCGCTCATGCTATAGTCGAT
TTCCAAAGGTTCGCACCCGT

Downstream 100 bases:

>100_bases
TTGCAATTCTTCCGGCAGTGCTTGCCGCAATACTCCTAATCCATTCAGTTTCCGTACCCGGTACCACGCTTGAAGTGAAC
CTCGCGACACAGGTGGGCCA

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MERRRLLHLAAAAAFQSHALERVRAAASAAGARTPEEIAADEDFWSEIRSAFSIDRNIVNFNNGYVSPSPRPVQDAMRRY
LEYTDMGPYHTMVATLEHQVEAVRRHLAQAAGCDAEEMAITRNASEALENAQYGIDLKPGDEVLTTDQDYPRMLTTYAQR
ERREGIVLKTISFPVPPPSMDDLYRRFEQAVTPRTKIIHFCHITNRTGQIFPVRKICRMARARNIATIVDGAHAFSHFPY
KISDLECDYYGTSLHKWTYAPIGTGFLYVRKSRIAGTWSMMASDKTQAGDIRKFEEIGTHPAANHNAISEALVFNQNLGI
DRKAARLRYLRDRWALRLARNPKCRILHSPDPEQSCGIGFLAFAPGIDAGKMREALWGKYNIITTYMPHTEYSGLRVTPN
IYSTLGEVDFFADMVEKELAS

Sequences:

>Translated_421_residues
MERRRLLHLAAAAAFQSHALERVRAAASAAGARTPEEIAADEDFWSEIRSAFSIDRNIVNFNNGYVSPSPRPVQDAMRRY
LEYTDMGPYHTMVATLEHQVEAVRRHLAQAAGCDAEEMAITRNASEALENAQYGIDLKPGDEVLTTDQDYPRMLTTYAQR
ERREGIVLKTISFPVPPPSMDDLYRRFEQAVTPRTKIIHFCHITNRTGQIFPVRKICRMARARNIATIVDGAHAFSHFPY
KISDLECDYYGTSLHKWTYAPIGTGFLYVRKSRIAGTWSMMASDKTQAGDIRKFEEIGTHPAANHNAISEALVFNQNLGI
DRKAARLRYLRDRWALRLARNPKCRILHSPDPEQSCGIGFLAFAPGIDAGKMREALWGKYNIITTYMPHTEYSGLRVTPN
IYSTLGEVDFFADMVEKELAS
>Mature_421_residues
MERRRLLHLAAAAAFQSHALERVRAAASAAGARTPEEIAADEDFWSEIRSAFSIDRNIVNFNNGYVSPSPRPVQDAMRRY
LEYTDMGPYHTMVATLEHQVEAVRRHLAQAAGCDAEEMAITRNASEALENAQYGIDLKPGDEVLTTDQDYPRMLTTYAQR
ERREGIVLKTISFPVPPPSMDDLYRRFEQAVTPRTKIIHFCHITNRTGQIFPVRKICRMARARNIATIVDGAHAFSHFPY
KISDLECDYYGTSLHKWTYAPIGTGFLYVRKSRIAGTWSMMASDKTQAGDIRKFEEIGTHPAANHNAISEALVFNQNLGI
DRKAARLRYLRDRWALRLARNPKCRILHSPDPEQSCGIGFLAFAPGIDAGKMREALWGKYNIITTYMPHTEYSGLRVTPN
IYSTLGEVDFFADMVEKELAS

Specific function: Catalyzes the reversible isomerization between isopenicillin N and penicillin N [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=251, Percent_Identity=24.7011952191235, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994898, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789175, Length=217, Percent_Identity=23.963133640553, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25143064, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129463, Length=208, Percent_Identity=29.8076923076923, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =5.1.1.17 [H]

Molecular weight: Translated: 47641; Mature: 47641

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRRLLHLAAAAAFQSHALERVRAAASAAGARTPEEIAADEDFWSEIRSAFSIDRNIVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEE
FNNGYVSPSPRPVQDAMRRYLEYTDMGPYHTMVATLEHQVEAVRRHLAQAAGCDAEEMAI
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TRNASEALENAQYGIDLKPGDEVLTTDQDYPRMLTTYAQRERREGIVLKTISFPVPPPSM
HCCHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCH
DDLYRRFEQAVTPRTKIIHFCHITNRTGQIFPVRKICRMARARNIATIVDGAHAFSHFPY
HHHHHHHHHHHCCHHHEEEEEEEECCCCCEECHHHHHHHHHHCCHHHHHCCHHHHHCCCE
KISDLECDYYGTSLHKWTYAPIGTGFLYVRKSRIAGTWSMMASDKTQAGDIRKFEEIGTH
EECCEECCCCCCCCCCEEECCCCCCEEEEEHHHHCCHHHHHHCCCCCCCHHHHHHHHCCC
PAANHNAISEALVFNQNLGIDRKAARLRYLRDRWALRLARNPKCRILHSPDPEQSCGIGF
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEE
LAFAPGIDAGKMREALWGKYNIITTYMPHTEYSGLRVTPNIYSTLGEVDFFADMVEKELA
EEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHC
S
C
>Mature Secondary Structure
MERRRLLHLAAAAAFQSHALERVRAAASAAGARTPEEIAADEDFWSEIRSAFSIDRNIVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEE
FNNGYVSPSPRPVQDAMRRYLEYTDMGPYHTMVATLEHQVEAVRRHLAQAAGCDAEEMAI
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TRNASEALENAQYGIDLKPGDEVLTTDQDYPRMLTTYAQRERREGIVLKTISFPVPPPSM
HCCHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCH
DDLYRRFEQAVTPRTKIIHFCHITNRTGQIFPVRKICRMARARNIATIVDGAHAFSHFPY
HHHHHHHHHHHCCHHHEEEEEEEECCCCCEECHHHHHHHHHHCCHHHHHCCHHHHHCCCE
KISDLECDYYGTSLHKWTYAPIGTGFLYVRKSRIAGTWSMMASDKTQAGDIRKFEEIGTH
EECCEECCCCCCCCCCEEECCCCCCEEEEEHHHHCCHHHHHHCCCCCCCHHHHHHHHCCC
PAANHNAISEALVFNQNLGIDRKAARLRYLRDRWALRLARNPKCRILHSPDPEQSCGIGF
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEE
LAFAPGIDAGKMREALWGKYNIITTYMPHTEYSGLRVTPNIYSTLGEVDFFADMVEKELA
EEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1694525; 2804141 [H]