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The map label for this gene is ntrY [H]

Identifier: 116622516

GI number: 116622516

Start: 4320723

End: 4322807

Strand: Reverse

Name: ntrY [H]

Synonym: Acid_3414

Alternate gene names: 116622516

Gene position: 4322807-4320723 (Counterclockwise)

Preceding gene: 116622519

Following gene: 116622515

Centisome position: 43.38

GC content: 63.02

Gene sequence:

>2085_bases
ATGAGAAAGCGACTGTTCTACGGGTCTGCCAGCGTGCTGCTCGTCCTCAGCGTGATACTCGTGGTGTGGCAGGGTTCCTT
CCGGCTCTACTATCTCTTCAGCCCTTCCAACCCTCAACAAACCTTTATTTATTGGGCCATCTCCACCCTGATCTTTATTT
TGATGGTCACCGTCGGCTGGATTCTGGCCCGTGAATTCATAAAACTTTACGTAGCCCGGCAGGCCAGGCGTCTCGGGTCC
CGAATTCGCACCAAGCTCGTGGTCGGCGCCATGTTGCTGAGCTGCGTGCCGGTAGTATTCCTGGTGCTCTGGAGCTGGGA
GGTTCTCAACGTCAACCTCAAGGCCTGGTTTACAAACCCGGTCGATAATCAGGTCGAAGTCTATAAAGACGCCGCCAAGG
CGCTCGACCAGGAGATCCAGCGCCGCCTCGCCGTCCAGGGCGCGCTGCTTGCCGCCCAACCCGAAACATCCCGCCTTTTG
AATACCGGCGAACGTACGCCCGAAGCGCTCGGACGGTTCGCGCAAAGCCAGGGTCTGGAATCGATCGCGATCTTCGCCGC
CGACGGCCACCCGCTCGAAACCTTCGGCCCCTTCCCCGCCCACCCCGTGGACGGCCAAATCTCCACTGTCCGCGTCCCTC
TCCCCAACGGCGCCATCGAGCTCGCCACCCGGCTTCCGCTCGATACCGGCAAGCGCCTCATGGAAATCAAGGCCTTCAGC
GATACCTGGGCCGAAATCGTCGGCAACCGCCAGGTATACCGCAACCTGTACACCATGCTGATGCTGCTGATCACCATGTT
CGTGCTCTTCGTCGCCACCTGGCTGGCGCGCCTCCTCGCCAACCGCATCAGCACCCCGATCACCGCCATACTCGAAGCCG
CCGACGAAGTTCGCAAAGGCAACCTTCAGCACCGTGTAACCGTTCGCGCCGAGGACGAGCTCGCCCTCCTCGTCAATGGC
TTCAACCAGATGACCGAAGCCCTCGAATCGAGCGGCCTCGAGCTGGACCGCCGCCGCCGCTTCACCGAAGCCATTCTCGA
GAGCATTCCCACCGGTGTCATGTCTATCGGCAGCGACGGCTCCATCCAACACGTCAACCAGGCCCTCTCCAAGATCTTTC
CCGGTGGCGCCGCGGCCCGCGCCATCCGCCTCGAAGACCTGTTCTCCCGCGAGGACACCACCGAGATCAAATACCTGATG
AAGCGCGCCCGCCGCACCGGCGTCGCCTTCCGCCAGTTGGAGCTGCGCACCGATACTCGCAAAATCCACCTCGCCGTCAC
GGTCTCCGCCCTGGAATCGAAATTGACCTCCGGCTACGTGGTCGTCCTCGAGGACACCACGGAGCTGTTCCGCGCGCAGA
AGGCCGCCGCCTGGCACGAAGTGGCCCGCCGGGTCGCGCACGAAATCAAGAATCCGCTGACCCCGATCGCTCTCTCCGCC
GAACGCATCGGCCGCCAGCTCGATCGCCTCGACCTGCCGCCCGGCGCCGCGCGCATCGTCTACGAATGCGCCGAGACCAT
TTCGAAATCGGTCGAATCCGTCAAAACCCTGGTGGACGAGTTCTCTCAGTTCGCCCGCTTCCCCTCCGCCCATCCCGTGC
GCAGCGATCTCAACGAAGTGGTCGGCGAGGCGCTCGCGGTATTTCACGGACGCCTGGAAGGGATTTCGATGCGCACCAGT
TTCGCGCCCGCGCTGCCGCCCGTGAATCTCGATCGCGAGCAGTTCCAGCGCGTTGTCGTCAACCTGGTGGACAACGCGGC
CGAGGCGATGCAGGACGCGCTCGTGAAAACACTCTACATCGCCACCCAACCAGGCCCCGCGGATACCGTGGAGCTCGTGG
TGGCCGATTCCGGCTGCGGGGTCAGCAGCGACGATAAGGAGAAACTCTTCCTGCCCTACTTCTCGACGAAGAATCGCGGT
ACCGGCCTGGGTCTCGCGATCGTGAGCCACATCGTGGCCGAGCACAATGCCCAAATCCGCGTGGAGGACAACCAGCCCGT
GGGAGCCCGTTTTACGGTGGAGCTTCCCGCCATCGTGGAAAACGAGGCGGCCGAGCCCCCCCTGCGCGCGGCCACCAGAG
TATGA

Upstream 100 bases:

>100_bases
TTTAAACGGAAAGCCGGTCGCACTTCGAAGAGCCCCCGCCCGAACAGCGCACGCTGCCGCGCGCATAGCACGTATAATCA
AAAGGAAGGACTTACCCCCC

Downstream 100 bases:

>100_bases
AGGCTCACCGGGTCCTGGTGGTGGATGACGAGCCCGCCATCCGCCAGTCCTTGAGCGGCGTCCTCGAGGACGAAGGTTAC
GCCGTGGAATCGGCCGAAAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MRKRLFYGSASVLLVLSVILVVWQGSFRLYYLFSPSNPQQTFIYWAISTLIFILMVTVGWILAREFIKLYVARQARRLGS
RIRTKLVVGAMLLSCVPVVFLVLWSWEVLNVNLKAWFTNPVDNQVEVYKDAAKALDQEIQRRLAVQGALLAAQPETSRLL
NTGERTPEALGRFAQSQGLESIAIFAADGHPLETFGPFPAHPVDGQISTVRVPLPNGAIELATRLPLDTGKRLMEIKAFS
DTWAEIVGNRQVYRNLYTMLMLLITMFVLFVATWLARLLANRISTPITAILEAADEVRKGNLQHRVTVRAEDELALLVNG
FNQMTEALESSGLELDRRRRFTEAILESIPTGVMSIGSDGSIQHVNQALSKIFPGGAAARAIRLEDLFSREDTTEIKYLM
KRARRTGVAFRQLELRTDTRKIHLAVTVSALESKLTSGYVVVLEDTTELFRAQKAAAWHEVARRVAHEIKNPLTPIALSA
ERIGRQLDRLDLPPGAARIVYECAETISKSVESVKTLVDEFSQFARFPSAHPVRSDLNEVVGEALAVFHGRLEGISMRTS
FAPALPPVNLDREQFQRVVVNLVDNAAEAMQDALVKTLYIATQPGPADTVELVVADSGCGVSSDDKEKLFLPYFSTKNRG
TGLGLAIVSHIVAEHNAQIRVEDNQPVGARFTVELPAIVENEAAEPPLRAATRV

Sequences:

>Translated_694_residues
MRKRLFYGSASVLLVLSVILVVWQGSFRLYYLFSPSNPQQTFIYWAISTLIFILMVTVGWILAREFIKLYVARQARRLGS
RIRTKLVVGAMLLSCVPVVFLVLWSWEVLNVNLKAWFTNPVDNQVEVYKDAAKALDQEIQRRLAVQGALLAAQPETSRLL
NTGERTPEALGRFAQSQGLESIAIFAADGHPLETFGPFPAHPVDGQISTVRVPLPNGAIELATRLPLDTGKRLMEIKAFS
DTWAEIVGNRQVYRNLYTMLMLLITMFVLFVATWLARLLANRISTPITAILEAADEVRKGNLQHRVTVRAEDELALLVNG
FNQMTEALESSGLELDRRRRFTEAILESIPTGVMSIGSDGSIQHVNQALSKIFPGGAAARAIRLEDLFSREDTTEIKYLM
KRARRTGVAFRQLELRTDTRKIHLAVTVSALESKLTSGYVVVLEDTTELFRAQKAAAWHEVARRVAHEIKNPLTPIALSA
ERIGRQLDRLDLPPGAARIVYECAETISKSVESVKTLVDEFSQFARFPSAHPVRSDLNEVVGEALAVFHGRLEGISMRTS
FAPALPPVNLDREQFQRVVVNLVDNAAEAMQDALVKTLYIATQPGPADTVELVVADSGCGVSSDDKEKLFLPYFSTKNRG
TGLGLAIVSHIVAEHNAQIRVEDNQPVGARFTVELPAIVENEAAEPPLRAATRV
>Mature_694_residues
MRKRLFYGSASVLLVLSVILVVWQGSFRLYYLFSPSNPQQTFIYWAISTLIFILMVTVGWILAREFIKLYVARQARRLGS
RIRTKLVVGAMLLSCVPVVFLVLWSWEVLNVNLKAWFTNPVDNQVEVYKDAAKALDQEIQRRLAVQGALLAAQPETSRLL
NTGERTPEALGRFAQSQGLESIAIFAADGHPLETFGPFPAHPVDGQISTVRVPLPNGAIELATRLPLDTGKRLMEIKAFS
DTWAEIVGNRQVYRNLYTMLMLLITMFVLFVATWLARLLANRISTPITAILEAADEVRKGNLQHRVTVRAEDELALLVNG
FNQMTEALESSGLELDRRRRFTEAILESIPTGVMSIGSDGSIQHVNQALSKIFPGGAAARAIRLEDLFSREDTTEIKYLM
KRARRTGVAFRQLELRTDTRKIHLAVTVSALESKLTSGYVVVLEDTTELFRAQKAAAWHEVARRVAHEIKNPLTPIALSA
ERIGRQLDRLDLPPGAARIVYECAETISKSVESVKTLVDEFSQFARFPSAHPVRSDLNEVVGEALAVFHGRLEGISMRTS
FAPALPPVNLDREQFQRVVVNLVDNAAEAMQDALVKTLYIATQPGPADTVELVVADSGCGVSSDDKEKLFLPYFSTKNRG
TGLGLAIVSHIVAEHNAQIRVEDNQPVGARFTVELPAIVENEAAEPPLRAATRV

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=25.8760107816712, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=30.672268907563, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI145693157, Length=365, Percent_Identity=23.2876712328767, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=398, Percent_Identity=22.3618090452261, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=24.2152466367713, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=23.2294617563739, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786837, Length=131, Percent_Identity=32.0610687022901, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=29.2035398230088, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76982; Mature: 76982

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRLFYGSASVLLVLSVILVVWQGSFRLYYLFSPSNPQQTFIYWAISTLIFILMVTVGW
CCCEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ILAREFIKLYVARQARRLGSRIRTKLVVGAMLLSCVPVVFLVLWSWEVLNVNLKAWFTNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEEEEECCC
VDNQVEVYKDAAKALDQEIQRRLAVQGALLAAQPETSRLLNTGERTPEALGRFAQSQGLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHCCCC
SIAIFAADGHPLETFGPFPAHPVDGQISTVRVPLPNGAIELATRLPLDTGKRLMEIKAFS
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHCCHHHHHHHHH
DTWAEIVGNRQVYRNLYTMLMLLITMFVLFVATWLARLLANRISTPITAILEAADEVRKG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
NLQHRVTVRAEDELALLVNGFNQMTEALESSGLELDRRRRFTEAILESIPTGVMSIGSDG
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHEECCCCC
SIQHVNQALSKIFPGGAAARAIRLEDLFSREDTTEIKYLMKRARRTGVAFRQLELRTDTR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHEEEECCCE
KIHLAVTVSALESKLTSGYVVVLEDTTELFRAQKAAAWHEVARRVAHEIKNPLTPIALSA
EEEEEEEHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECH
ERIGRQLDRLDLPPGAARIVYECAETISKSVESVKTLVDEFSQFARFPSAHPVRSDLNEV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VGEALAVFHGRLEGISMRTSFAPALPPVNLDREQFQRVVVNLVDNAAEAMQDALVKTLYI
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ATQPGPADTVELVVADSGCGVSSDDKEKLFLPYFSTKNRGTGLGLAIVSHIVAEHNAQIR
EECCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
VEDNQPVGARFTVELPAIVENEAAEPPLRAATRV
EECCCCCCCEEEEECCHHHCCCCCCCCHHHHCCC
>Mature Secondary Structure
MRKRLFYGSASVLLVLSVILVVWQGSFRLYYLFSPSNPQQTFIYWAISTLIFILMVTVGW
CCCEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ILAREFIKLYVARQARRLGSRIRTKLVVGAMLLSCVPVVFLVLWSWEVLNVNLKAWFTNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEEEEECCC
VDNQVEVYKDAAKALDQEIQRRLAVQGALLAAQPETSRLLNTGERTPEALGRFAQSQGLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHCCCC
SIAIFAADGHPLETFGPFPAHPVDGQISTVRVPLPNGAIELATRLPLDTGKRLMEIKAFS
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCHHCCHHHHHHHHH
DTWAEIVGNRQVYRNLYTMLMLLITMFVLFVATWLARLLANRISTPITAILEAADEVRKG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
NLQHRVTVRAEDELALLVNGFNQMTEALESSGLELDRRRRFTEAILESIPTGVMSIGSDG
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHEECCCCC
SIQHVNQALSKIFPGGAAARAIRLEDLFSREDTTEIKYLMKRARRTGVAFRQLELRTDTR
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHEEEECCCE
KIHLAVTVSALESKLTSGYVVVLEDTTELFRAQKAAAWHEVARRVAHEIKNPLTPIALSA
EEEEEEEHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECH
ERIGRQLDRLDLPPGAARIVYECAETISKSVESVKTLVDEFSQFARFPSAHPVRSDLNEV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VGEALAVFHGRLEGISMRTSFAPALPPVNLDREQFQRVVVNLVDNAAEAMQDALVKTLYI
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ATQPGPADTVELVVADSGCGVSSDDKEKLFLPYFSTKNRGTGLGLAIVSHIVAEHNAQIR
EECCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
VEDNQPVGARFTVELPAIVENEAAEPPLRAATRV
EECCCCCCCEEEEECCHHHCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]