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The map label for this gene is fimB [C]

Identifier: 116622415

GI number: 116622415

Start: 4189671

End: 4190615

Strand: Direct

Name: fimB [C]

Synonym: Acid_3311

Alternate gene names: 116622415

Gene position: 4189671-4190615 (Clockwise)

Preceding gene: 116622414

Following gene: 116622416

Centisome position: 42.04

GC content: 60.53

Gene sequence:

>945_bases
ATGAATCCGCTGGCCAAAGGTATCCGTGACTACCTGGCTTTGCGTCGTGGCCTGGGGTTCAAGCTGGTTCGGCATGAGGC
TGGGCTGAAGGAGTTCGCGTCCTTCCTGGCGCGAAAACGCAGTTCTCACATCACCGTTGCCTTGGCATTGGAGTGGGCGA
CCCAGCATGCCCAACAGCAGCCGGCTGAATGGACGGCGCGACTCTGCGTTGTGCGTGGCTTCGCCCGTTACTGGAGCGCC
ACGGATCCGTTGACCGAAGTTCCACCGCTGGGGCTGCTGCCCTATCGTCCCGCACGCGCTCAACCATATTTCTATTCCGA
TCACGAAATCCGGAAACTGCTGAGGGCTGCTAAAACGCGACCTTCTATCGACCCTCTGCGGCCCTGCACCTACCACTGCC
TTTTCGGCTTGCTGGCAGTCACAGGCCTGCGGTTGGGCGAGGCGCTCGGCCTTCGACTTGGGGATATGGATTGGTCGGAA
GGCATTCTCACGATTCGAGGGGCCAAGTTCGGAAAGTCCCGTCTGGTTCCGCTGCATACCTCGACTTGTAAAGTCCTGGC
CGACTACGCGAAGCGCCGGGATGAGCGCTTCGGCGCGCGAGCAGAGGGGTATTTCCTGGTCAACCTGAACGGTAACCGGC
TGGACAAAGGCGAGGTCCACCGGGCGTTTTACCTGCTGTCCCGACAGATTGGATTGCGTGCTGTGGACGCCAGCCGCGGC
CCGCGGCTGCACGATTTTCGACACCGATTTGCGGTCGAGACTCTGTTGCGCTGGTATCGCAACGGCGAAGACCCCAAGCG
GCGCTTACCCATCTTGTCCACCTATCTCGGGCATGCCCACGTAACCGATACCTATTGGTATCTGACCGGCACTCCCGAAC
TGTTGGGAGCGGCCAATAAGCGGCTGGAGAAACGGTGGGAGGCCTTGAATGCGGGATCCCGCTAA

Upstream 100 bases:

>100_bases
AACTGCTGCGGCACCAGAGCCCCAACACGACGGCGATCTACGCCAAAGTAGACGTCACCGCCTTGCACACCTTGGCGTTG
CCGTGGCCGGGAGGTGGCCG

Downstream 100 bases:

>100_bases
TCTTGCTGCCTTGCTGCAGTCTTTCTTCACCACGCGTTTGATGGCGCAGCGGAAAGTCAGCCCCCATACCATCGCCTCGT
ATCGCGATACGTTCCGCCTG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNPLAKGIRDYLALRRGLGFKLVRHEAGLKEFASFLARKRSSHITVALALEWATQHAQQQPAEWTARLCVVRGFARYWSA
TDPLTEVPPLGLLPYRPARAQPYFYSDHEIRKLLRAAKTRPSIDPLRPCTYHCLFGLLAVTGLRLGEALGLRLGDMDWSE
GILTIRGAKFGKSRLVPLHTSTCKVLADYAKRRDERFGARAEGYFLVNLNGNRLDKGEVHRAFYLLSRQIGLRAVDASRG
PRLHDFRHRFAVETLLRWYRNGEDPKRRLPILSTYLGHAHVTDTYWYLTGTPELLGAANKRLEKRWEALNAGSR

Sequences:

>Translated_314_residues
MNPLAKGIRDYLALRRGLGFKLVRHEAGLKEFASFLARKRSSHITVALALEWATQHAQQQPAEWTARLCVVRGFARYWSA
TDPLTEVPPLGLLPYRPARAQPYFYSDHEIRKLLRAAKTRPSIDPLRPCTYHCLFGLLAVTGLRLGEALGLRLGDMDWSE
GILTIRGAKFGKSRLVPLHTSTCKVLADYAKRRDERFGARAEGYFLVNLNGNRLDKGEVHRAFYLLSRQIGLRAVDASRG
PRLHDFRHRFAVETLLRWYRNGEDPKRRLPILSTYLGHAHVTDTYWYLTGTPELLGAANKRLEKRWEALNAGSR
>Mature_314_residues
MNPLAKGIRDYLALRRGLGFKLVRHEAGLKEFASFLARKRSSHITVALALEWATQHAQQQPAEWTARLCVVRGFARYWSA
TDPLTEVPPLGLLPYRPARAQPYFYSDHEIRKLLRAAKTRPSIDPLRPCTYHCLFGLLAVTGLRLGEALGLRLGDMDWSE
GILTIRGAKFGKSRLVPLHTSTCKVLADYAKRRDERFGARAEGYFLVNLNGNRLDKGEVHRAFYLLSRQIGLRAVDASRG
PRLHDFRHRFAVETLLRWYRNGEDPKRRLPILSTYLGHAHVTDTYWYLTGTPELLGAANKRLEKRWEALNAGSR

Specific function: Fimb Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fimb Switches

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35828; Mature: 35828

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLAKGIRDYLALRRGLGFKLVRHEAGLKEFASFLARKRSSHITVALALEWATQHAQQQ
CCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHCC
PAEWTARLCVVRGFARYWSATDPLTEVPPLGLLPYRPARAQPYFYSDHEIRKLLRAAKTR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCC
PSIDPLRPCTYHCLFGLLAVTGLRLGEALGLRLGDMDWSEGILTIRGAKFGKSRLVPLHT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEECCCCCCCCEEEECH
STCKVLADYAKRRDERFGARAEGYFLVNLNGNRLDKGEVHRAFYLLSRQIGLRAVDASRG
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEECCCCC
PRLHDFRHRFAVETLLRWYRNGEDPKRRLPILSTYLGHAHVTDTYWYLTGTPELLGAANK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHCCCEEECEEEEEECCHHHHHHHHH
RLEKRWEALNAGSR
HHHHHHHHHCCCCC
>Mature Secondary Structure
MNPLAKGIRDYLALRRGLGFKLVRHEAGLKEFASFLARKRSSHITVALALEWATQHAQQQ
CCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHCC
PAEWTARLCVVRGFARYWSATDPLTEVPPLGLLPYRPARAQPYFYSDHEIRKLLRAAKTR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHCC
PSIDPLRPCTYHCLFGLLAVTGLRLGEALGLRLGDMDWSEGILTIRGAKFGKSRLVPLHT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEECCCCCCCCEEEECH
STCKVLADYAKRRDERFGARAEGYFLVNLNGNRLDKGEVHRAFYLLSRQIGLRAVDASRG
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEECCCCC
PRLHDFRHRFAVETLLRWYRNGEDPKRRLPILSTYLGHAHVTDTYWYLTGTPELLGAANK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHCCCEEECEEEEEECCHHHHHHHHH
RLEKRWEALNAGSR
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]