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The map label for this gene is yccK [H]

Identifier: 116622410

GI number: 116622410

Start: 4183838

End: 4184833

Strand: Reverse

Name: yccK [H]

Synonym: Acid_3305

Alternate gene names: 116622410

Gene position: 4184833-4183838 (Counterclockwise)

Preceding gene: 116622411

Following gene: 116622409

Centisome position: 41.99

GC content: 59.04

Gene sequence:

>996_bases
ATGCAAAAACGTAAGCTGGGGCAAAGCACCCTTGAACTGTCTGCTCTCGGTCTCGGTTGCATGGGGATGAGTTGGTCCTA
CAGCCCGATTCCGGACCGGCACGCGATGATCTCGCTGCTGCGCTCCGCCGCGGAGCGGGGCGTCACGTTTTTCGATACGG
CCGAAGTTTACGGTCCATACACGAACGAGGAACTGGTCGGCGAGGCTCTCGCTCCCTTCCGGAGCCGAGTGGTGATCGCA
ACGAAGTTCGGTTGGGCGCCCGGTTCCGAGGACGAAACCAGGTGGAGCAGGCTGAATTCCCGACCGGAGCACATCAAGCA
GGCTGTCGAGGGCTCCCTCAAGCGACTGCGGGTTGACACCGTCGACTTGTATTACCAGCACCGGGTTGATCCCGCCGTTC
CGATTGAAGACGTGGCGGGCGCGGTTAAGGATCTGATCCAGGCGGGTAAGGTCAAACATTTCGGCCTGTCCGAAGCAGCG
GCAATCACGATTCGCCGTGCACACGCTGTTCAGCCGGTGGCGGCCGTGCAGAGCGAGTATTCACTGTGGTATCGCGAACC
GGAACGGGAAGTCCTACCGACCCTCGAAGAACTGGGGATCGGCTTCGTTCCATTCAGCCCGCTCGGGAAGGGTTTCCTTA
CGGGGAAGATCGACCAAAACACGACCTTTGACAGTTCCGACTTCCGCAATTCCGTGCCTCGCTTCAATGCCGAAAACCGG
AAGGCCAACTTCGCCTTGATCGGTCTGCTGGAGGGCGTCGCGAAGCGAAAGAACGCCACACCGGGCCAAATCGCGCTTGC
GTGGTTGTTGGCGCAGAAGCCTTGGATTGTGCCTATTCCCGGCACGACCAAACTGCATCGTCTGGAAGAGAACATCGGAG
CCGCGGCGGTGACGCTTACAACAAGTGAGCTGAGAGACATCGAAGAGGCCGCTGAACGGATACCAGTGCAAGGTGCTCGT
TACCCGGAGCAAATGGAAAAGTTGAGTAACCGATAA

Upstream 100 bases:

>100_bases
AGGACCTACCGCGTTCCTATGAGTTTTCGGGCAATCAACTGATCATCAAATCTACTCGTGCCGATGAGCATTGGCGTGTT
ACTTGGGAGCGATATTGAGT

Downstream 100 bases:

>100_bases
AGGAGAACTATGCGAGGAACAGTTTTGTACGGGCCCCGTGACATCCGGTTCGAAGATCGGGAAGATCCCAGGATCGAAAA
ACCGACTGACGCCGTGATCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQKRKLGQSTLELSALGLGCMGMSWSYSPIPDRHAMISLLRSAAERGVTFFDTAEVYGPYTNEELVGEALAPFRSRVVIA
TKFGWAPGSEDETRWSRLNSRPEHIKQAVEGSLKRLRVDTVDLYYQHRVDPAVPIEDVAGAVKDLIQAGKVKHFGLSEAA
AITIRRAHAVQPVAAVQSEYSLWYREPEREVLPTLEELGIGFVPFSPLGKGFLTGKIDQNTTFDSSDFRNSVPRFNAENR
KANFALIGLLEGVAKRKNATPGQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAAAVTLTTSELRDIEEAAERIPVQGAR
YPEQMEKLSNR

Sequences:

>Translated_331_residues
MQKRKLGQSTLELSALGLGCMGMSWSYSPIPDRHAMISLLRSAAERGVTFFDTAEVYGPYTNEELVGEALAPFRSRVVIA
TKFGWAPGSEDETRWSRLNSRPEHIKQAVEGSLKRLRVDTVDLYYQHRVDPAVPIEDVAGAVKDLIQAGKVKHFGLSEAA
AITIRRAHAVQPVAAVQSEYSLWYREPEREVLPTLEELGIGFVPFSPLGKGFLTGKIDQNTTFDSSDFRNSVPRFNAENR
KANFALIGLLEGVAKRKNATPGQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAAAVTLTTSELRDIEEAAERIPVQGAR
YPEQMEKLSNR
>Mature_331_residues
MQKRKLGQSTLELSALGLGCMGMSWSYSPIPDRHAMISLLRSAAERGVTFFDTAEVYGPYTNEELVGEALAPFRSRVVIA
TKFGWAPGSEDETRWSRLNSRPEHIKQAVEGSLKRLRVDTVDLYYQHRVDPAVPIEDVAGAVKDLIQAGKVKHFGLSEAA
AITIRRAHAVQPVAAVQSEYSLWYREPEREVLPTLEELGIGFVPFSPLGKGFLTGKIDQNTTFDSSDFRNSVPRFNAENR
KANFALIGLLEGVAKRKNATPGQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAAAVTLTTSELRDIEEAAERIPVQGAR
YPEQMEKLSNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=339, Percent_Identity=30.0884955752212, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI27436969, Length=339, Percent_Identity=29.7935103244838, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4504825, Length=336, Percent_Identity=29.7619047619048, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436966, Length=339, Percent_Identity=30.0884955752212, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436962, Length=339, Percent_Identity=30.0884955752212, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436971, Length=313, Percent_Identity=32.5878594249201, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=29.7202797202797, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41327764, Length=278, Percent_Identity=28.4172661870504, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI41152114, Length=291, Percent_Identity=29.553264604811, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI87081735, Length=340, Percent_Identity=33.2352941176471, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=30.7228915662651, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787674, Length=317, Percent_Identity=30.9148264984227, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=30.4878048780488, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=27.8592375366569, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994888, Length=296, Percent_Identity=29.3918918918919, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788081, Length=282, Percent_Identity=24.468085106383, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=31.0650887573964, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6325384, Length=340, Percent_Identity=29.1176470588235, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=310, Percent_Identity=26.1290322580645, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=24.1496598639456, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=292, Percent_Identity=24.6575342465753, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=24.5967741935484, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=351, Percent_Identity=24.7863247863248, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=351, Percent_Identity=24.7863247863248, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36692; Mature: 36692

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRKLGQSTLELSALGLGCMGMSWSYSPIPDRHAMISLLRSAAERGVTFFDTAEVYGPY
CCCHHHCCHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCC
TNEELVGEALAPFRSRVVIATKFGWAPGSEDETRWSRLNSRPEHIKQAVEGSLKRLRVDT
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VDLYYQHRVDPAVPIEDVAGAVKDLIQAGKVKHFGLSEAAAITIRRAHAVQPVAAVQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHH
SLWYREPEREVLPTLEELGIGFVPFSPLGKGFLTGKIDQNTTFDSSDFRNSVPRFNAENR
HHHHCCCHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCC
KANFALIGLLEGVAKRKNATPGQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAAAVTLT
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEE
TSELRDIEEAAERIPVQGARYPEQMEKLSNR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQKRKLGQSTLELSALGLGCMGMSWSYSPIPDRHAMISLLRSAAERGVTFFDTAEVYGPY
CCCHHHCCHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCC
TNEELVGEALAPFRSRVVIATKFGWAPGSEDETRWSRLNSRPEHIKQAVEGSLKRLRVDT
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VDLYYQHRVDPAVPIEDVAGAVKDLIQAGKVKHFGLSEAAAITIRRAHAVQPVAAVQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHH
SLWYREPEREVLPTLEELGIGFVPFSPLGKGFLTGKIDQNTTFDSSDFRNSVPRFNAENR
HHHHCCCHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCC
KANFALIGLLEGVAKRKNATPGQIALAWLLAQKPWIVPIPGTTKLHRLEENIGAAAVTLT
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEE
TSELRDIEEAAERIPVQGARYPEQMEKLSNR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]