Click here to switch to the map view.

The map label for this gene is rhmA [H]

Identifier: 116622387

GI number: 116622387

Start: 4153931

End: 4154716

Strand: Direct

Name: rhmA [H]

Synonym: Acid_3281

Alternate gene names: 116622387

Gene position: 4153931-4154716 (Clockwise)

Preceding gene: 116622385

Following gene: 116622388

Centisome position: 41.68

GC content: 62.72

Gene sequence:

>786_bases
ATGCGCATTAATACGACCAGGGAACGCCTTGCCAAGGGCGAGGTGGTTTACGGCTGCGGCCTGCAGGTATACCGCGCTCC
GGAGATTCCGCGTCTCTTCGCAGCGACGGGCTTTGATTATGTGTTCATCGACATGGAACACGGTTCGTTCAATCTGGAGA
CCGCCCACGATGTGATCATCTCGTGCCGGCTGGCCGGGATTACGCCGATCGTGCGCGTGGGTGAGCTGCAATATACGCTG
TGCGCGCGCCTGCTGGATCAGGGAGCGCAAGGAATCATTCTGCCGCGCGTGGAAGATCCGAAGGTCCTGGAGGAGGCGCT
GAGCTGGATGCGGTTCCCGCCGCTCGGCAAGCGCGGGTACGGCATCAATCCGACGATGTTGGATTACGAGGCGCGCAGCA
TCTCCGAGGTCATGGAACACCAGAATCGCGAGACCCTGACCGTGGTGCAGTTCGAGACCGTGGCCGCGGTGGAACGCGCC
GACGAGCTGCTCTCGCTCAAGGGCCTGGACGTGATGATGATCGGGCCTGCCGACCTTTCGATCGCGCTCGGGATCCCCGG
GCAGTTCGATCATCCACTGCTGGTGGAGACCATCGACAAGGTGATCGCCAAGTGCAACCAGCACGGAGTGGTGCCGGGCA
TTCAGACGCGCGGCGTGGCCATGGCGAAATTCTGGGCCGATCGCGGCATGCGTTTCGTGGGCGTGGCGGCGGAGCACGTC
TTCCTGATGGAGAAGTGCAAGGAAGCCATGGCGGCGCTGCGCCCGGCTAAGGCGGCGAAATCATGA

Upstream 100 bases:

>100_bases
CACATGGACTGTTCGCTCCAGGGATTGCGGTGGACGGGTTGTGGGCCGCGGCAAAACTAGCGGACAGTCATAGGCAGACG
ATTCAAGATAGCATAGCTTC

Downstream 100 bases:

>100_bases
TCGACCGTTTCCCGCTGGGCTACAACACGTACTCGATTCGCGCGCTGAAGTGGCACGACCTGCCCCTGATCGATTACGCG
GCGCAATTGAAACTGGACGC

Product: HpcH/HpaI aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRINTTRERLAKGEVVYGCGLQVYRAPEIPRLFAATGFDYVFIDMEHGSFNLETAHDVIISCRLAGITPIVRVGELQYTL
CARLLDQGAQGIILPRVEDPKVLEEALSWMRFPPLGKRGYGINPTMLDYEARSISEVMEHQNRETLTVVQFETVAAVERA
DELLSLKGLDVMMIGPADLSIALGIPGQFDHPLLVETIDKVIAKCNQHGVVPGIQTRGVAMAKFWADRGMRFVGVAAEHV
FLMEKCKEAMAALRPAKAAKS

Sequences:

>Translated_261_residues
MRINTTRERLAKGEVVYGCGLQVYRAPEIPRLFAATGFDYVFIDMEHGSFNLETAHDVIISCRLAGITPIVRVGELQYTL
CARLLDQGAQGIILPRVEDPKVLEEALSWMRFPPLGKRGYGINPTMLDYEARSISEVMEHQNRETLTVVQFETVAAVERA
DELLSLKGLDVMMIGPADLSIALGIPGQFDHPLLVETIDKVIAKCNQHGVVPGIQTRGVAMAKFWADRGMRFVGVAAEHV
FLMEKCKEAMAALRPAKAAKS
>Mature_261_residues
MRINTTRERLAKGEVVYGCGLQVYRAPEIPRLFAATGFDYVFIDMEHGSFNLETAHDVIISCRLAGITPIVRVGELQYTL
CARLLDQGAQGIILPRVEDPKVLEEALSWMRFPPLGKRGYGINPTMLDYEARSISEVMEHQNRETLTVVQFETVAAVERA
DELLSLKGLDVMMIGPADLSIALGIPGQFDHPLLVETIDKVIAKCNQHGVVPGIQTRGVAMAKFWADRGMRFVGVAAEHV
FLMEKCKEAMAALRPAKAAKS

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=254, Percent_Identity=29.1338582677165, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789514, Length=241, Percent_Identity=28.2157676348548, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: NA

Molecular weight: Translated: 28854; Mature: 28854

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINTTRERLAKGEVVYGCGLQVYRAPEIPRLFAATGFDYVFIDMEHGSFNLETAHDVII
CCCCCHHHHHHCCCEEEECCEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHE
SCRLAGITPIVRVGELQYTLCARLLDQGAQGIILPRVEDPKVLEEALSWMRFPPLGKRGY
EEECCCCCCHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
GINPTMLDYEARSISEVMEHQNRETLTVVQFETVAAVERADELLSLKGLDVMMIGPADLS
CCCCCEECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEE
IALGIPGQFDHPLLVETIDKVIAKCNQHGVVPGIQTRGVAMAKFWADRGMRFVGVAAEHV
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHH
FLMEKCKEAMAALRPAKAAKS
HHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MRINTTRERLAKGEVVYGCGLQVYRAPEIPRLFAATGFDYVFIDMEHGSFNLETAHDVII
CCCCCHHHHHHCCCEEEECCEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHE
SCRLAGITPIVRVGELQYTLCARLLDQGAQGIILPRVEDPKVLEEALSWMRFPPLGKRGY
EEECCCCCCHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
GINPTMLDYEARSISEVMEHQNRETLTVVQFETVAAVERADELLSLKGLDVMMIGPADLS
CCCCCEECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEE
IALGIPGQFDHPLLVETIDKVIAKCNQHGVVPGIQTRGVAMAKFWADRGMRFVGVAAEHV
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHH
FLMEKCKEAMAALRPAKAAKS
HHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA